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Cruises from Santiago to Buenos Aires

Are you looking for a cruise from Santiago to Buenos Aires? February and November are the most popular months to cruise between Santiago and Buenos Aires and there are 30 departures available from eight of the world's leading cruise lines.
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13 Days
31 Days
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14 Cruises (30 Cruise Departures)
24 Day Antarctica & Falklands - From Punta Arenas To Buenos Aires with HX Expeditions
Cruise

24 Days (23 Nights) Santiago to Buenos Aires
Cruise Line: HX Expeditions
Ship: MS Fram
Departures: Mar 2026 to Mar 2027
Countries Visited: Chile, Antarctica, Falkland Islands, Argentina
Anniversary Offers
Inside
-
Oceanview
$17,926
Balcony
-
Suite
$21,277
Save
10,151
From
17,926
per person
View Trip
31 Day Chilean Fjords, Glaciers & Antarctic Wildlife Explorer with Scenic
Cruise

31 Days (30 Nights) Santiago to Buenos Aires
Cruise Line: Scenic
Ships: Scenic Eclipse I
Departure: 04 November 2026
Countries Visited: Chile, Argentina, Falkland Islands, South Georgia Island, Antarctica
Fly Free Premium EconomyFly Free Business Class
Inside
-
Oceanview
-
Balcony
$50,271
Suite
$65,271
Save
48,544
From
50,271
per person
View Trip
15 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (2)

15 Days (14 Nights) Santiago to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departure: 23 February 2027
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Deal
Inside
$2,314
Oceanview
$2,564
Balcony
$3,564
Suite
$4,664
From
2,314
per person
View Trip
22 Day Puerto Williams to Buenos Aires with Silversea
Cruise

22 Days (21 Nights) Santiago to Buenos Aires
Cruise Line: Silversea
Ship: Silver Endeavour
Departure: 04 March 2027
Countries Visited: Chile, Antarctica, South Georgia Island, Falkland Islands, Argentina
Port-to-PortDoor-to-Door Upgrade Option
Inside
-
Oceanview
-
Balcony
-
Suite
$28,100
From
28,100
per person
View Trip
13 Day Chilean Fjords & The Glaciers of The Beagle Channel with Scenic
Cruise

13 Days (12 Nights) Santiago to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 04 November 2026
Countries Visited: Chile, Argentina
Fly Free Premium EconomyFly Free Business Class
Inside
-
Oceanview
-
Balcony
$19,403
Suite
$25,403
Save
19,587
From
19,403
per person
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (2)

16 Days (15 Nights) Santiago to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departure: 04 December 2026
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Deal
Inside
$2,364
Oceanview
$2,614
Balcony
$3,564
Suite
$4,564
From
2,364
per person
View Trip
16 Day Cape Horn & Glaciers of Patagonia with Princess
Cruise
 (5)

16 Days (15 Nights) Santiago to Buenos Aires
Cruise Line: Princess
Ship: Majestic Princess
Departure: 22 December 2026
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Exclusive DealLove Boat Sale
Inside
$2,993
Oceanview
-
Balcony
$3,737
Suite
$4,843
From
2,993
per person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (4)

18 Days (17 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Jupiter
Departures: Dec 2025 to Feb 2028
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Viking $1,799 Air Deal
Inside
-
Oceanview
-
Balcony
$6,999
Suite
$12,499
From
6,999
per person
View Trip
23 Day Patagonian Adventure and the Weddell Sea - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

23 Days Santiago to Buenos Aires
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 26 November 2026
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Chile, Argentina, Antarctica
Fly Free Premium EconomyFly Free Business Class
Inside
-
Oceanview
-
Balcony
$42,423
Suite
$49,423
Save
24,832
From
42,423
per person
View Trip
18 Day Antarctic Voyage with Chile with APT
Tour + Cruise

18 Days Santiago to Buenos Aires
Operated By: APT
Ship: Seabourn Venture
Departure: 14 February 2026
Trip Styles: Cruise, Scenic
Countries Visited: Chile, Argentina, Antarctica
Inside
-
Oceanview
-
Balcony
$21,095
Suite
-
Save
500
From
21,095
per person
View Trip
17 Day Edge Of The World Expedition with Regent Seven Seas
Cruise

17 Days (16 Nights) Santiago to Buenos Aires
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 01 February 2026
Countries Visited: Chile, Argentina, Uruguay
Inside
-
Oceanview
-
Balcony
$12,899
Suite
$13,999
Save
19,099
From
12,899
per person
View Trip
20 Day Wonders of Patagonia and Antarctica - Cruise & Land Journey with Scenic
Tour + Cruise

20 Days Santiago to Buenos Aires
Operated By: Scenic
Ships: Scenic Eclipse I, Scenic Eclipse II
Departures: Feb 2026 to Feb 2027
Trip Styles: Coach, Cruise, Scenic
Countries Visited: Chile, Antarctica, Argentina
Fly Free Premium EconomyFly Free Business Class
Inside
-
Oceanview
-
Balcony
$38,460
Suite
$45,873
Save
22,507
From
38,460
per person
View Trip
13 Day Chilean Fjords & Scenic Shores with Viking Cruises
Cruise

13 Days (12 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Oct 2025 to Oct 2028
Countries Visited: Chile, Argentina
Viking $999 Air DealFlights Included
Inside
-
Oceanview
-
Balcony
$9,995
Suite
$12,995
Save
1,000
From
9,995
per person
View Trip
17 Day Cape Horn & Strait of Magellan with Princess
Cruise

17 Days (16 Nights) Santiago to Buenos Aires
Cruise Line: Princess
Ship: Sapphire Princess
Departure: 06 December 2025
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Exclusive DealLove Boat Sale
Inside
$2,619
Oceanview
$3,669
Balcony
$4,089
Suite
$5,419
From
2,619
per person
View Trip
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