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Cruises from Santiago to Buenos Aires

Are you looking for a cruise from Santiago to Buenos Aires? November and February are the most popular months to cruise between Santiago and Buenos Aires and there are 27 departures available from seven of the world's leading cruise lines.
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14 Cruises (27 Cruise Departures)
18 Day Antarctic Voyage with Chile with APT
Tour + Cruise

18 Days Santiago to Buenos Aires
Operated By: APT
Ship: Seabourn Venture
Departure: 06 February 2027
Trip Styles: Cruise, Scenic
Visit: Chile, Argentina, Antarctica
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$19,045
Suite
$21,593
From
US$19,045
Save 350
Per Person
View Trip
24 Day Antarctica & Falklands - From Punta Arenas To Buenos Aires with HX Expeditions
Cruise

24 Days (23 Nights) Santiago to Buenos Aires
Cruise Line: HX Expeditions
Ship: MS Fram
Departure: 20 March 2026
Visit: Chile, Antarctica, Falkland Islands, Argentina
Bonus Onboard Credit
Exclusive Savings
Inside
-
Oceanview
$14,837
Balcony
-
Suite
$19,775
From
US$14,837
Save 6,485
Per Person
View Trip
22 Day Puerto Williams to Buenos Aires with Silversea
Cruise

22 Days (21 Nights) Santiago to Buenos Aires
Cruise Line: Silversea
Ship: Silver Endeavour
Departure: 04 March 2027
Visit: Chile, Antarctica, South Georgia Island, Saint Helena, Argentina
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$23,220
Suite
-
From
US$23,220
Save 2,580
Per Person
View Trip
15 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (2)

15 Days (14 Nights) Santiago to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departures: Feb 2027 to Feb 2028
Visit: Chile, Argentina, Falkland Islands, Uruguay
Fare Saver
Book Early & Have It All Fare Option
Inside
$2,089
Oceanview
$2,289
Balcony
$3,189
Suite
$4,221
From
US$2,089
Per Person
View Trip
24 Day Ultimate Chilean Fjords & Antarctica’s Weddell Sea with Scenic
New ReleaseCruise

24 Days (23 Nights) Santiago to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 13 November 2027
Visit: Chile, Argentina, Antarctica
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$84,842
Suite
$112,390
From
US$84,842
Save 2,438
Per Person
View Trip
16 Day Cape Horn & Glaciers of Patagonia with Princess
Cruise
 (7)

16 Days (15 Nights) Santiago to Buenos Aires
Cruise Line: Princess
Ship: Majestic Princess
Departure: 22 December 2026
Visit: Chile, Argentina, Falkland Islands, Uruguay
Princess Standard
Inside
$2,182
Oceanview
-
Balcony
$2,796
Suite
$3,452
From
US$2,182
Per Person
View Trip
13 Day Chilean Fjords & The Glaciers of The Beagle Channel with Scenic
Cruise

13 Days (12 Nights) Santiago to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 04 November 2026
Visit: Chile, Argentina
Wave Offer
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,686
Suite
$19,857
From
US$15,686
Save 22,704
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (6)

18 Days (17 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Jupiter
Departures: Dec 2026 to Feb 2028
Visit: Chile, Argentina, Falkland Islands, Uruguay
Viking $1,799 Air Deal
Inside
-
Oceanview
-
Balcony
$7,599
Suite
$12,999
From
US$7,599
Per Person
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (2)

16 Days (15 Nights) Santiago to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departures: Dec 2026 to Dec 2027
Visit: Chile, Argentina, Falkland Islands, Uruguay
Fare Saver
Book Early & Have It All Fare Option
Inside
$2,224
Oceanview
$2,324
Balcony
$3,224
Suite
$4,452
From
US$2,224
Per Person
View Trip
31 Day Chilean Fjords, Glaciers & Antarctic Wildlife Explorer with Scenic
Cruise

31 Days (30 Nights) Santiago to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 04 November 2026
Visit: Chile, Argentina, Falkland Islands, South Georgia Island, Antarctica
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$94,501
Suite
$125,056
From
US$94,501
Save 2,814
Per Person
View Trip
13 Day Chilean Fjords & Scenic Shores with Viking Cruises
Cruise
 (1)

13 Days (12 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Nov 2026 to Oct 2028
Visit: Chile, Argentina
Flights Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,995
Suite
$14,995
From
US$9,995
Save 500
Per Person
View Trip
23 Day Patagonian Adventure and the Weddell Sea - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

23 Days Santiago to Buenos Aires
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 26 November 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Antarctica
Fly Free Business Class
Fly Free Premium Economy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$42,053
Suite
$48,029
From
US$42,053
Save 26,882
Per Person
View Trip
20 Day Wonders of Patagonia and Antarctica - Cruise & Land Journey with Scenic
Tour + Cruise

20 Days Santiago to Buenos Aires
Operated By: Scenic
Ships: Scenic Eclipse I, Scenic Eclipse II
Departures: Feb 2026 to Feb 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Antarctica, Argentina
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$35,103
Suite
$39,735
From
US$35,103
Save 27,502
Per Person
View Trip
13 Day Chairman’s Voyage: Chilean Fjords & The Glaciers of The Beagle Channel with Scenic
Cruise

13 Days (12 Nights) Santiago to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 13 November 2027
Visit: Chile, Argentina
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$20,355
Suite
$25,998
From
US$20,355
Save 20,635
Per Person
View Trip
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