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Central America & Panama Cruises with Royal Caribbean

Central America & Panama Cruises with Royal Caribbean

Join Royal Caribbean on one of 12 cruises navigating the coastline of Central America including Columbia, Guatemala, Belize, Panama and Honduras this season. January is the most popular month to begin your cruise and Royal Caribbean have 200 cruises departing between May 2025 and April 2027.
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12 Cruises (200 Cruise Departures)
17 Day Panama Canal Cruise with Royal Caribbean
Cruise

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Royal Caribbean
Ship: Radiance of the Seas
Departure: 04 October 2025
Countries Visited: USA, Mexico, Guatemala, Costa Rica (+3 more), Panama, Colombia, Cayman Islands
Latest Offer
INSIDE
$3,445
OCEANVIEW
-
BALCONY
-
SUITE
-
Save (per person) 1,359
From (per person) 3,445
View Trip
7 Day Western Caribbean Cruise with Royal Caribbean
Cruise

7 Days (6 Nights) Galveston to Galveston
Cruise Line: Royal Caribbean
Ships: Harmony of the Seas, Symphony of the Seas
Departures: Jun 2025 to Sep 2026
Countries Visited: USA, Mexico, Honduras
Flash DealLatest Offer
INSIDE
$758
OCEANVIEW
$901
BALCONY
$780
SUITE
$1,918
Save (per person) 657
From (per person) 758
View Trip
8 Day Western Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Tampa to Tampa
Cruise Line: Royal Caribbean
Ships: Enchantment of the Seas, Grandeur of the Seas
Departures: Nov 2025 to Oct 2026
Countries Visited: USA, Mexico, Belize, Honduras
Latest Offer
INSIDE
$513
OCEANVIEW
$564
BALCONY
$1,128
SUITE
$1,467
Save (per person) 483
From (per person) 513
View Trip
8 Day Western Caribbean Holiday Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Tampa to Tampa
Cruise Line: Royal Caribbean
Ships: Enchantment of the Seas, Grandeur of the Seas, Rhapsody of the Seas
Departures: Jun 2025 to Apr 2027
Countries Visited: USA, Mexico, Honduras, Belize
Latest Offer
INSIDE
$532
OCEANVIEW
$582
BALCONY
$1,238
SUITE
$1,427
Save (per person) 593
From (per person) 532
View Trip
8 Day Western Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Galveston to Galveston
Cruise Line: Royal Caribbean
Ship: Symphony of the Seas
Departures: Nov 2026 to Apr 2027
Countries Visited: USA, Mexico, Honduras
Latest Offer
INSIDE
$820
OCEANVIEW
$902
BALCONY
$1,085
SUITE
$2,009
Save (per person) 648
From (per person) 820
View Trip
8 Day Western Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Tampa to Tampa
Cruise Line: Royal Caribbean
Ship: Enchantment of the Seas
Departure: 17 January 2027
Countries Visited: USA, Honduras, Belize, Mexico
Latest Offer
INSIDE
$684
OCEANVIEW
$801
BALCONY
$1,397
SUITE
$1,572
Save (per person) 358
From (per person) 684
View Trip
8 Day Western Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Tampa to Tampa
Cruise Line: Royal Caribbean
Ships: Enchantment of the Seas, Grandeur of the Seas, Rhapsody of the Seas
Departures: Oct 2025 to Feb 2027
Countries Visited: USA, Mexico, Belize, Honduras
Latest Offer
INSIDE
$535
OCEANVIEW
$622
BALCONY
$1,253
SUITE
$1,428
Save (per person) 533
From (per person) 535
View Trip
8 Day Western Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Galveston to Galveston
Cruise Line: Royal Caribbean
Ships: Allure of the Seas, Harmony of the Seas, Symphony of the Seas
Departures: Jun 2025 to Mar 2027
Countries Visited: USA, Honduras, Mexico
Latest Offer
INSIDE
$668
OCEANVIEW
$788
BALCONY
$771
SUITE
$2,039
Save (per person) 663
From (per person) 668
View Trip
14 Day Panama Canal Eastward Cruise with Royal Caribbean
Cruise

14 Days (13 Nights) San Diego to Miami
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 19 September 2025
Countries Visited: USA, Mexico, Costa Rica, Panama (+1 more), Colombia
Latest OfferExclusive Solo Offer
INSIDE
$1,630
OCEANVIEW
$2,177
BALCONY
$6,101
SUITE
-
Save (per person) 602
From (per person) 1,630
View Trip
11 Day Panama Canal Westward Cruise with Royal Caribbean
Cruise

11 Days (10 Nights) Colon to Los Angeles
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 25 April 2026
Countries Visited: Panama, Costa Rica, Mexico, USA
Latest OfferExclusive Solo Offer
INSIDE
$1,186
OCEANVIEW
$1,485
BALCONY
$1,888
SUITE
$2,803
Save (per person) 464
From (per person) 1,186
View Trip
8 Day Western Caribbean & Perfect Day with Royal Caribbean
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Royal Caribbean
Ship: Icon Of The Seas
Departures: May 2025 to Apr 2027
Countries Visited: USA, Mexico, Honduras, Bahamas
Flash DealLatest Offer
INSIDE
$1,388
OCEANVIEW
$1,598
BALCONY
$1,668
SUITE
$2,588
Save (per person) 1,334
From (per person) 1,388
View Trip
8 Day Southern Caribbean Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 20 December 2025
Countries Visited: Panama, Colombia, Curacao, Aruba
Latest Offer
INSIDE
$1,213
OCEANVIEW
$1,254
BALCONY
$1,383
SUITE
$1,633
Save (per person) 609
From (per person) 1,213
View Trip
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