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Royal Caribbean Cruises from San Diego

Start your journey from San Diego with 15 unique Royal Caribbean cruise itineraries to choose from. March is the most popular month to begin your cruise from San Diego and Royal Caribbean have 48 trips departing this season.
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15 Cruises (48 Departures)
15 Cruises (48 Departures)
Departures
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Duration
3 Days
16 Days
Price
$400pp
$4,352pp
Countries
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5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Tour Operator: Royal Caribbean
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Feb 2027 to Mar 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$611
Oceanview
$670
Balcony
$788
Suite
$1,159
From (Per Person)
A$611
Save 228
Per Person
View Trip
8 Day Ensenada, Cabo & Mazatlan with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Tour Operator: Royal Caribbean
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Feb 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$924
Oceanview
$986
Balcony
$1,164
Suite
$2,675
From (Per Person)
A$924
Save 443
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Tour Operator: Royal Caribbean
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$554
Oceanview
$643
Balcony
$692
Suite
$1,078
From (Per Person)
A$554
Save 346
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Tour Operator: Royal Caribbean
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 28 January 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$996
Oceanview
$1,028
Balcony
$1,353
Suite
$3,001
From (Per Person)
A$996
Save 587
Per Person
View Trip
8 Day Pacific Coastal Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to Vancouver
Tour Operator: Royal Caribbean
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 May 2027
Visits: USA, Canada
Exclusive Savings
Inside
$1,011
Oceanview
$1,004
Balcony
$1,307
Suite
-
From (Per Person)
A$1,004
Save 534
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Tour Operator: Royal Caribbean
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Mar 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$552
Oceanview
$571
Balcony
$672
Suite
$1,007
From (Per Person)
A$552
Save 339
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Tour Operator: Royal Caribbean
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Nov 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$904
Oceanview
$933
Balcony
$1,195
Suite
$3,380
From (Per Person)
A$904
Save 623
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Tour Operator: Royal Caribbean
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$861
Oceanview
$918
Balcony
$1,200
Suite
$2,296
From (Per Person)
A$861
Save 624
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Tour Operator: Royal Caribbean
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 March 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$628
Oceanview
$711
Balcony
$824
Suite
$1,119
From (Per Person)
A$628
Save 254
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Tour Operator: Royal Caribbean
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Dec 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$1,109
Oceanview
$1,245
Balcony
$1,531
Suite
$2,727
From (Per Person)
A$1,109
Save 720
Per Person
View Trip
8 Day Cabo Overnight, Catalina & Ensenada with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Tour Operator: Royal Caribbean
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 13 December 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$907
Oceanview
$971
Balcony
$1,206
Suite
$5,333
From (Per Person)
A$907
Save 411
Per Person
View Trip
16 Day Panama Canal Eastward Cruise with Royal Caribbean
Cruise

16 Days (15 Nights) San Diego to Tampa
Tour Operator: Royal Caribbean
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 October 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Exclusive Savings
Inside
$3,038
Oceanview
$3,431
Balcony
$6,298
Suite
-
From (Per Person)
A$3,038
Save 1,314
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Tour Operator: Royal Caribbean
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 27 December 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$1,595
Oceanview
$1,767
Balcony
$2,044
Suite
$3,620
From (Per Person)
A$1,595
Save 965
Per Person
View Trip
3 Day Ensenada Cruise with Royal Caribbean
Cruise

3 Days (2 Nights) San Diego to San Diego
Tour Operator: Royal Caribbean
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 October 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$461
Oceanview
$489
Balcony
$560
Suite
$913
From (Per Person)
A$461
Save 267
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Tour Operator: Royal Caribbean
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Dec 2026 to Apr 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$528
Oceanview
$553
Balcony
$646
Suite
$1,013
From (Per Person)
A$528
Save 331
Per Person
View Trip
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