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Royal Caribbean Cruises from San Diego

Start your journey from San Diego with 13 unique Royal Caribbean cruise itineraries to choose from. March is the most popular month to begin your cruise from San Diego and Royal Caribbean have 43 trips departing this season.
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13 Cruises (43 Departures)
13 Cruises (43 Departures)
Departures
Duration
4 Days
16 Days
Price
$200pp
$3,136pp
Countries
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5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Feb 2027 to Mar 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$308
Oceanview
$350
Balcony
$362
Suite
$684
From (Per Person)
US$308
Save 164
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Jan 2027 to Mar 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$282
Oceanview
$312
Balcony
$344
Suite
$547
From (Per Person)
US$332
Save 186
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$499
Oceanview
$529
Balcony
$691
Suite
$1,739
From (Per Person)
US$499
Save 343
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Dec 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$549
Oceanview
$559
Balcony
$1,049
Suite
$1,748
From (Per Person)
US$549
Save 495
Per Person
View Trip
16 Day Panama Canal Eastward Cruise with Royal Caribbean
Cruise

16 Days (15 Nights) San Diego to Tampa
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 October 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Exclusive Savings
Inside
$2,227
Oceanview
-
Balcony
-
Suite
-
From (Per Person)
US$3,086
Save 50
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 28 January 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$498
Oceanview
$558
Balcony
$901
Suite
$1,828
From (Per Person)
US$765
Save 50
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Apr 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$290
Oceanview
$297
Balcony
$307
Suite
$685
From (Per Person)
US$291
Save 207
Per Person
View Trip
8 Day Ensenada, Cabo & Mazatlan with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Feb 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$457
Oceanview
$499
Balcony
$637
Suite
$1,649
From (Per Person)
US$457
Save 299
Per Person
View Trip
8 Day Cabo Overnight, Catalina & Ensenada with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 13 December 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$426
Oceanview
$436
Balcony
$517
Suite
$2,454
From (Per Person)
US$426
Save 277
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Nov 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$507
Oceanview
$607
Balcony
$657
Suite
-
From (Per Person)
US$507
Save 304
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 27 December 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$949
Oceanview
$1,269
Balcony
$1,630
Suite
$2,149
From (Per Person)
US$949
Save 502
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Dec 2026 to Apr 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$259
Oceanview
$257
Balcony
$266
Suite
$549
From (Per Person)
US$257
Save 210
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 March 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$329
Oceanview
$439
Balcony
$472
Suite
$696
From (Per Person)
US$478
Save 25
Per Person
View Trip
Results: 13 results

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