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Royal Caribbean Cruises from San Diego

Start your journey from San Diego with 15 unique Royal Caribbean cruise itineraries to choose from. March is the most popular month to begin your cruise from San Diego and Royal Caribbean have 48 trips departing this season.
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15 Cruises (48 Departures)
15 Cruises (48 Departures)
Departures
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Duration
3 Days
16 Days
Price
$500pp
$4,414pp
Countries
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5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$596
Oceanview
$641
Balcony
$707
Suite
$1,132
From (Per Person)
A$596
Save 277
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$935
Oceanview
$1,005
Balcony
$1,210
Suite
$2,405
From (Per Person)
A$935
Save 451
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Mar 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$539
Oceanview
$594
Balcony
$670
Suite
$1,049
From (Per Person)
A$601
Save 230
Per Person
View Trip
8 Day Cabo Overnight, Catalina & Ensenada with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 13 December 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$927
Oceanview
$991
Balcony
$1,168
Suite
$2,534
From (Per Person)
A$927
Save 424
Per Person
View Trip
8 Day Pacific Coastal Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to Vancouver
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 May 2027
Visits: USA, Canada
Exclusive Savings
Inside
$1,003
Oceanview
$1,025
Balcony
$1,335
Suite
$2,961
From (Per Person)
A$1,003
Save 385
Per Person
View Trip
8 Day Ensenada, Cabo & Mazatlan with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Feb 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$924
Oceanview
$986
Balcony
$1,164
Suite
$2,220
From (Per Person)
A$924
Save 443
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 27 December 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$1,742
Oceanview
$1,925
Balcony
$2,225
Suite
$3,876
From (Per Person)
A$2,030
Save 632
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Dec 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$1,136
Oceanview
$1,272
Balcony
$1,565
Suite
$2,712
From (Per Person)
A$1,304
Save 486
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Feb 2027 to Mar 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$627
Oceanview
$670
Balcony
$788
Suite
$1,173
From (Per Person)
A$627
Save 228
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Dec 2026 to Apr 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$534
Oceanview
$539
Balcony
$646
Suite
$1,032
From (Per Person)
A$534
Save 251
Per Person
View Trip
16 Day Panama Canal Eastward Cruise with Royal Caribbean
Cruise

16 Days (15 Nights) San Diego to Tampa
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 October 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Exclusive Savings
Inside
$3,080
Oceanview
$3,431
Balcony
$6,070
Suite
-
From (Per Person)
A$3,550
Save 864
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Nov 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$963
Oceanview
$1,042
Balcony
$1,195
Suite
$2,876
From (Per Person)
A$963
Save 477
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 March 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$654
Oceanview
$741
Balcony
$862
Suite
$1,174
From (Per Person)
A$654
Save 228
Per Person
View Trip
3 Day Ensenada Cruise with Royal Caribbean
Cruise

3 Days (2 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 October 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$458
Oceanview
$514
Balcony
$629
Suite
$1,102
From (Per Person)
A$504
Save 204
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 28 January 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$975
Oceanview
$1,028
Balcony
$1,305
Suite
$2,909
From (Per Person)
A$1,031
Save 418
Per Person
View Trip
Results: 15 results

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