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Royal Caribbean Cruises from San Diego

Start your journey from San Diego with 14 unique Royal Caribbean cruise itineraries to choose from. March is the most popular month to begin your cruise from San Diego and Royal Caribbean have 46 trips departing this season.
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14 Cruises (46 Departures)
14 Cruises (46 Departures)
Departures
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Duration
4 Days
16 Days
Price
$300pp
$4,915pp
Countries
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5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$370
Oceanview
$384
Balcony
$537
Suite
$1,119
From (Per Person)
A$370
Save 334
Per Person
View Trip
8 Day Pacific Coastal Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to Vancouver
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 May 2027
Visits: USA, Canada
Exclusive Savings
Inside
$1,043
Oceanview
-
Balcony
-
Suite
$5,774
From (Per Person)
A$1,204
Save 390
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Dec 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$1,000
Oceanview
$1,014
Balcony
$1,169
Suite
$2,787
From (Per Person)
A$1,000
Save 798
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 28 January 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$986
Oceanview
$989
Balcony
$1,394
Suite
$2,844
From (Per Person)
A$1,044
Save 383
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 March 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$639
Oceanview
$713
Balcony
$753
Suite
$1,158
From (Per Person)
A$639
Save 207
Per Person
View Trip
16 Day Panama Canal Eastward Cruise with Royal Caribbean
Cruise

16 Days (15 Nights) San Diego to Tampa
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 October 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Exclusive Savings
Inside
$3,422
Oceanview
-
Balcony
-
Suite
-
From (Per Person)
A$4,094
Save 821
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$1,008
Oceanview
$1,084
Balcony
$1,102
Suite
$2,720
From (Per Person)
A$1,008
Save 407
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Nov 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$429
Oceanview
$1,039
Balcony
$819
Suite
-
From (Per Person)
A$429
Save 178
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 27 December 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$1,486
Oceanview
$1,600
Balcony
$2,141
Suite
$3,327
From (Per Person)
A$2,099
Save 188
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Mar 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$524
Oceanview
$538
Balcony
$559
Suite
$972
From (Per Person)
A$524
Save 292
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Dec 2026 to Apr 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$324
Oceanview
$339
Balcony
$451
Suite
$996
From (Per Person)
A$324
Save 331
Per Person
View Trip
8 Day Ensenada, Cabo & Mazatlan with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Feb 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$399
Oceanview
$1,031
Balcony
$556
Suite
$2,652
From (Per Person)
A$399
Save 374
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Feb 2027 to Mar 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$604
Oceanview
$683
Balcony
$625
Suite
$1,177
From (Per Person)
A$604
Save 320
Per Person
View Trip
8 Day Cabo Overnight, Catalina & Ensenada with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 13 December 2026
Visits: USA, Mexico
Inside
$569
Oceanview
$788
Balcony
$930
Suite
$3,763
From (Per Person)
A$569
Per Person
View Trip
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