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Royal Caribbean Cruises from San Diego

Start your journey from San Diego with 14 unique Royal Caribbean cruise itineraries to choose from. March is the most popular month to begin your cruise from San Diego and Royal Caribbean have 47 trips departing this season.
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8 Days
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$1,764pp
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14 Cruises (47 Cruise Departures)
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Feb 2027 to Mar 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$452
Oceanview
$542
Balcony
$615
Suite
$704
From
US$452
Save 225
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Nov 2026
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$749
Oceanview
$899
Balcony
$1,112
Suite
$1,702
From
US$749
Save 391
Per Person
View Trip
3 Day Ensenada Cruise with Royal Caribbean
Cruise

3 Days (2 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 October 2026
Visit: USA, Mexico
Exclusive Savings
Inside
$358
Oceanview
$409
Balcony
$521
Suite
$761
From
US$358
Save 178
Per Person
View Trip
8 Day Ensenada, Cabo & Mazatlan with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Feb 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$713
Oceanview
$877
Balcony
$969
Suite
$1,935
From
US$713
Save 391
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 March 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$482
Oceanview
$582
Balcony
$645
Suite
$785
From
US$482
Save 221
Per Person
View Trip
8 Day Cabo Overnight, Catalina & Ensenada with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 13 December 2026
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$743
Oceanview
$903
Balcony
$1,155
Suite
$1,836
From
US$743
Save 395
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Mar 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$394
Oceanview
$464
Balcony
$557
Suite
$657
From
US$394
Save 246
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 27 December 2026
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$1,181
Oceanview
$1,319
Balcony
$1,713
Suite
$2,882
From
US$1,181
Save 583
Per Person
View Trip
8 Day Pacific Coastal Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to Vancouver
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 May 2027
Visit: USA, Canada
Bonus Onboard Credit
Latest Offer
Exclusive Savings
Inside
$658
Oceanview
$688
Balcony
$838
Suite
$1,638
From
US$658
Save 331
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Dec 2026
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$971
Oceanview
$1,131
Balcony
$1,384
Suite
$2,163
From
US$971
Save 537
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Dec 2026 to Apr 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$404
Oceanview
$479
Balcony
$554
Suite
$657
From
US$404
Save 226
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$452
Oceanview
$513
Balcony
$575
Suite
$695
From
US$452
Save 255
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 28 January 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$698
Oceanview
$908
Balcony
$1,050
Suite
$2,123
From
US$698
Save 385
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$692
Oceanview
$852
Balcony
$1,004
Suite
$1,592
From
US$692
Save 416
Per Person
View Trip
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