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Royal Caribbean Cruises from San Diego

Start your journey from San Diego with 14 unique Royal Caribbean cruise itineraries to choose from. March is the most popular month to begin your cruise from San Diego and Royal Caribbean have 47 trips departing this season.
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8 Days
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14 Cruises (47 Cruise Departures)
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 March 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$482
Oceanview
$582
Balcony
$645
Suite
$785
From
US$482
Save 221
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Mar 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$394
Oceanview
$464
Balcony
$557
Suite
$657
From
US$394
Save 254
Per Person
View Trip
8 Day Pacific Coastal Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to Vancouver
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 May 2027
Visit: USA, Canada
Bonus Onboard Credit
Exclusive Savings
Inside
$658
Oceanview
$676
Balcony
$838
Suite
$1,638
From
US$658
Save 331
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 27 December 2026
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$1,100
Oceanview
$1,170
Balcony
$1,562
Suite
$2,633
From
US$1,100
Save 549
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Dec 2026
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$901
Oceanview
$1,101
Balcony
$1,363
Suite
$1,934
From
US$901
Save 520
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$447
Oceanview
$504
Balcony
$575
Suite
$695
From
US$447
Save 246
Per Person
View Trip
8 Day Cabo Overnight, Catalina & Ensenada with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 13 December 2026
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$733
Oceanview
$853
Balcony
$1,115
Suite
$1,795
From
US$733
Save 391
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Dec 2026 to Apr 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$404
Oceanview
$458
Balcony
$551
Suite
$651
From
US$404
Save 226
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 28 January 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$698
Oceanview
$908
Balcony
$1,050
Suite
$2,123
From
US$698
Save 385
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Nov 2026
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$690
Oceanview
$840
Balcony
$1,082
Suite
$1,472
From
US$690
Save 382
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$669
Oceanview
$831
Balcony
$1,004
Suite
$1,562
From
US$669
Save 416
Per Person
View Trip
8 Day Ensenada, Cabo & Mazatlan with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Feb 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$652
Oceanview
$842
Balcony
$969
Suite
$1,495
From
US$652
Save 400
Per Person
View Trip
3 Day Ensenada Cruise with Royal Caribbean
Cruise

3 Days (2 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 October 2026
Visit: USA, Mexico
Exclusive Savings
Inside
$309
Oceanview
$388
Balcony
$451
Suite
$751
From
US$309
Save 156
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Feb 2027 to Mar 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$452
Oceanview
$542
Balcony
$615
Suite
$704
From
US$452
Save 225
Per Person
View Trip
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