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Royal Caribbean Cruises from San Diego

Start your journey from San Diego with 14 unique Royal Caribbean cruise itineraries to choose from. March is the most popular month to begin your cruise from San Diego and Royal Caribbean have 45 trips departing this season.
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3 Days
14 Days
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$2,235pp
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14 Cruises (45 Cruise Departures)
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 March 2027
Countries Visited: USA, Mexico
Latest Offer + Bonus Onboard CreditLatest OfferExclusive Savings
Inside
$502
Oceanview
$602
Balcony
$672
Suite
$797
Save
229
From
502
per person
View Trip
8 Day Cabo, Mazatlan & La Paz with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 28 January 2027
Countries Visited: USA, Mexico
Latest OfferExclusive Savings
Inside
$698
Oceanview
$908
Balcony
$1,029
Suite
$2,223
Save
385
From
698
per person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Nov 2026
Countries Visited: USA, Mexico
Latest OfferExclusive Savings
Inside
$710
Oceanview
$880
Balcony
$1,133
Suite
$1,782
Save
386
From
710
per person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 27 December 2026
Countries Visited: USA, Mexico
Latest OfferExclusive Savings
Inside
$1,148
Oceanview
$1,288
Balcony
$1,608
Suite
$2,943
Save
569
From
1,148
per person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Dec 2026 to Apr 2027
Countries Visited: USA, Mexico
Latest Offer + Bonus Onboard CreditLatest OfferExclusive Savings
Inside
$414
Oceanview
$498
Balcony
$574
Suite
$679
Save
217
From
414
per person
View Trip
3 Day Ensenada Cruise with Royal Caribbean
Cruise

3 Days (2 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 October 2026
Countries Visited: USA, Mexico
Latest Offer + Bonus Onboard CreditLatest OfferExclusive Savings
Inside
$339
Oceanview
$388
Balcony
$491
Suite
$711
Save
169
From
339
per person
View Trip
8 Day Cabo Overnight, Catalina & Ensenada with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 13 December 2026
Countries Visited: USA, Mexico
Latest OfferExclusive Savings
Inside
$733
Oceanview
$883
Balcony
$1,115
Suite
$1,936
Save
391
From
733
per person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Feb 2027 to Mar 2027
Countries Visited: USA, Mexico
Latest Offer + Bonus Onboard CreditLatest OfferExclusive Savings
Inside
$462
Oceanview
$562
Balcony
$642
Suite
$727
Save
229
From
462
per person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Mar 2027
Countries Visited: USA, Mexico
Latest Offer + Bonus Onboard CreditLatest OfferExclusive Savings
Inside
$405
Oceanview
$485
Balcony
$577
Suite
$680
Save
225
From
405
per person
View Trip
8 Day Ensenada, Cabo & Mazatlan with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Feb 2027
Countries Visited: USA, Mexico
Latest OfferExclusive Savings
Inside
$693
Oceanview
$882
Balcony
$1,000
Suite
$2,035
Save
395
From
693
per person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Countries Visited: USA, Mexico
Latest Offer + Bonus Onboard CreditLatest OfferExclusive Savings
Inside
$452
Oceanview
$533
Balcony
$605
Suite
$695
Save
251
From
452
per person
View Trip
14 Day Panama Canal Eastward Cruise with Royal Caribbean
Cruise

14 Days (13 Nights) San Diego to Miami
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 19 September 2025
Countries Visited: USA, Mexico, Costa Rica, Panama, Colombia
Latest OfferExclusive Savings
Inside
$1,608
Oceanview
$2,200
Balcony
$3,779
Suite
-
From
2,210
per person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Mar 2027
Countries Visited: USA, Mexico
Latest OfferExclusive Savings
Inside
$710
Oceanview
$871
Balcony
$1,035
Suite
$1,724
Save
428
From
710
per person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Dec 2026
Countries Visited: USA, Mexico
Latest OfferExclusive Savings
Inside
$921
Oceanview
$1,141
Balcony
$1,314
Suite
$2,263
Save
528
From
921
per person
View Trip
Results: 14 results

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