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Royal Caribbean Cruises from San Diego

Start your journey from San Diego with 14 unique Royal Caribbean cruise itineraries to choose from. March is the most popular month to begin your cruise from San Diego and Royal Caribbean have 47 trips departing this season.
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8 Days
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14 Cruises (47 Cruise Departures)
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 March 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$472
Oceanview
$562
Balcony
$624
Suite
$774
From
US$472
Save 217
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Dec 2026
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$941
Oceanview
$1,091
Balcony
$1,444
Suite
$1,984
From
US$941
Save 533
Per Person
View Trip
8 Day Pacific Coastal Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to Vancouver
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 May 2027
Visit: USA, Canada
Bonus Onboard Credit
Exclusive Savings
Inside
$636
Oceanview
$665
Balcony
$848
Suite
$1,708
From
US$636
Save 322
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$443
Oceanview
$492
Balcony
$555
Suite
$703
From
US$443
Save 291
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 28 January 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$680
Oceanview
$881
Balcony
$1,013
Suite
$2,123
From
US$680
Save 378
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Dec 2026 to Apr 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$370
Oceanview
$418
Balcony
$494
Suite
$590
From
US$370
Save 233
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Feb 2027 to Mar 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$442
Oceanview
$512
Balcony
$584
Suite
$715
From
US$442
Save 221
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Mar 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$384
Oceanview
$445
Balcony
$537
Suite
$647
From
US$384
Save 242
Per Person
View Trip
8 Day Cabo Overnight, Catalina & Ensenada with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 13 December 2026
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$683
Oceanview
$853
Balcony
$1,115
Suite
$1,816
From
US$683
Save 370
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$650
Oceanview
$802
Balcony
$964
Suite
$1,462
From
US$650
Save 408
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Nov 2026
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$700
Oceanview
$819
Balcony
$1,102
Suite
$1,482
From
US$700
Save 382
Per Person
View Trip
3 Day Ensenada Cruise with Royal Caribbean
Cruise

3 Days (2 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 October 2026
Visit: USA, Mexico
Exclusive Savings
Inside
$306
Oceanview
$376
Balcony
$469
Suite
$746
From
US$306
Save 173
Per Person
View Trip
8 Day Ensenada, Cabo & Mazatlan with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Feb 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$653
Oceanview
$842
Balcony
$939
Suite
$1,485
From
US$653
Save 378
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 27 December 2026
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$1,150
Oceanview
$1,201
Balcony
$1,653
Suite
$2,683
From
US$1,150
Save 571
Per Person
View Trip
Results: 14 results

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