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Royal Caribbean Cruises from San Diego

Start your journey from San Diego with 15 unique Royal Caribbean cruise itineraries to choose from. March is the most popular month to begin your cruise from San Diego and Royal Caribbean have 48 trips departing this season.
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15 Cruises (48 Departures)
15 Cruises (48 Departures)
Departures
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Duration
3 Days
16 Days
Price
$400pp
$4,497pp
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8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 27 December 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$1,829
Oceanview
$2,025
Balcony
$2,323
Suite
$4,133
From (Per Person)
A$1,829
Save 960
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Nov 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$926
Oceanview
$1,010
Balcony
$1,171
Suite
$2,641
From (Per Person)
A$926
Save 478
Per Person
View Trip
8 Day Cabo Overnight, Catalina & Ensenada with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 13 December 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$963
Oceanview
$995
Balcony
$1,172
Suite
$2,223
From (Per Person)
A$963
Save 453
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 28 January 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$984
Oceanview
$1,028
Balcony
$1,305
Suite
$2,983
From (Per Person)
A$984
Save 582
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Dec 2026 to Apr 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$510
Oceanview
$543
Balcony
$675
Suite
$1,042
From (Per Person)
A$510
Save 331
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 March 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$628
Oceanview
$741
Balcony
$862
Suite
$1,202
From (Per Person)
A$628
Save 254
Per Person
View Trip
16 Day Panama Canal Eastward Cruise with Royal Caribbean
Cruise

16 Days (15 Nights) San Diego to Tampa
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 October 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Exclusive Savings
Inside
$3,137
Oceanview
$3,514
Balcony
$5,973
Suite
-
From (Per Person)
A$3,137
Save 1,360
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Dec 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$1,224
Oceanview
$1,360
Balcony
$1,549
Suite
$2,871
From (Per Person)
A$1,224
Save 738
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Mar 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$539
Oceanview
$594
Balcony
$688
Suite
$1,059
From (Per Person)
A$539
Save 301
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$960
Oceanview
$1,010
Balcony
$1,228
Suite
$2,535
From (Per Person)
A$960
Save 616
Per Person
View Trip
8 Day Pacific Coastal Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to Vancouver
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 May 2027
Visits: USA, Canada
Exclusive Savings
Inside
$1,020
Oceanview
$1,043
Balcony
$1,388
Suite
$3,007
From (Per Person)
A$1,020
Save 389
Per Person
View Trip
8 Day Ensenada, Cabo & Mazatlan with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Feb 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$898
Oceanview
$1,006
Balcony
$1,167
Suite
$2,153
From (Per Person)
A$898
Save 446
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$588
Oceanview
$641
Balcony
$740
Suite
$1,161
From (Per Person)
A$588
Save 346
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Feb 2027 to Mar 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$601
Oceanview
$670
Balcony
$788
Suite
$1,186
From (Per Person)
A$601
Save 249
Per Person
View Trip
3 Day Ensenada Cruise with Royal Caribbean
Cruise

3 Days (2 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 October 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$475
Oceanview
$518
Balcony
$660
Suite
$1,148
From (Per Person)
A$475
Save 258
Per Person
View Trip
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