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Royal Caribbean Cruises from San Diego

Start your journey from San Diego with 15 unique Royal Caribbean cruise itineraries to choose from. March is the most popular month to begin your cruise from San Diego and Royal Caribbean have 48 trips departing this season.
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15 Cruises (48 Departures)
15 Cruises (48 Departures)
Departures
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Duration
3 Days
16 Days
Price
$500pp
$4,519pp
Countries
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8 Day Pacific Coastal Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to Vancouver
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 May 2027
Visits: USA, Canada
Exclusive Savings
Inside
$1,036
Oceanview
$1,018
Balcony
$1,335
Suite
-
From (Per Person)
A$1,018
Save 540
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$548
Oceanview
$620
Balcony
$593
Suite
$1,163
From (Per Person)
A$548
Save 367
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$833
Oceanview
$833
Balcony
$1,049
Suite
$2,465
From (Per Person)
A$833
Save 634
Per Person
View Trip
16 Day Panama Canal Eastward Cruise with Royal Caribbean
Cruise

16 Days (15 Nights) San Diego to Tampa
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 October 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Exclusive Savings
Inside
$3,152
Oceanview
$3,502
Balcony
$6,337
Suite
-
From (Per Person)
A$3,152
Save 1,367
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Mar 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$521
Oceanview
$549
Balcony
$549
Suite
$991
From (Per Person)
A$521
Save 325
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Nov 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$888
Oceanview
$888
Balcony
$1,071
Suite
$3,894
From (Per Person)
A$888
Save 705
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 27 December 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$1,569
Oceanview
$1,723
Balcony
$2,012
Suite
$3,562
From (Per Person)
A$1,569
Save 839
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Dec 2026 to Apr 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$521
Oceanview
$554
Balcony
$563
Suite
$951
From (Per Person)
A$521
Save 341
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 28 January 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$974
Oceanview
$987
Balcony
$1,347
Suite
$2,780
From (Per Person)
A$974
Save 577
Per Person
View Trip
3 Day Ensenada Cruise with Royal Caribbean
Cruise

3 Days (2 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 October 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$390
Oceanview
$417
Balcony
$417
Suite
$1,596
From (Per Person)
A$673
Save 103
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Dec 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$1,152
Oceanview
$1,319
Balcony
$1,384
Suite
$2,675
From (Per Person)
A$1,152
Save 646
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Feb 2027 to Mar 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$578
Oceanview
$681
Balcony
$619
Suite
$1,137
From (Per Person)
A$578
Save 225
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 March 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$647
Oceanview
$711
Balcony
$817
Suite
$1,119
From (Per Person)
A$647
Save 242
Per Person
View Trip
8 Day Ensenada, Cabo & Mazatlan with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Feb 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$858
Oceanview
$1,051
Balcony
$1,040
Suite
$2,464
From (Per Person)
A$858
Save 448
Per Person
View Trip
8 Day Cabo Overnight, Catalina & Ensenada with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 13 December 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$939
Oceanview
$1,095
Balcony
$1,133
Suite
-
From (Per Person)
A$939
Save 391
Per Person
View Trip
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