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Royal Caribbean Cruises from Colon

Start your journey from Colon with 18 unique Royal Caribbean cruise itineraries to choose from. March, April and January are the most popular months to begin your cruise from Colon and Royal Caribbean have 77 trips departing this season.
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18 Cruises (77 Cruise Departures)
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Sep 2026 to Apr 2028
Visit: Panama, Colombia, Bonaire, Aruba, Curacao
Bonus Onboard Credit
Exclusive Savings
Inside
$973
Oceanview
$1,009
Balcony
$1,282
Suite
$1,567
From
US$973
Save 536
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 13 February 2027
Visit: Panama, Colombia, Aruba, Bonaire
Bonus Onboard Credit
Exclusive Savings
Inside
$773
Oceanview
$883
Balcony
$1,273
Suite
$1,288
From
US$773
Save 450
Per Person
View Trip
11 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

11 Days (10 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 14 November 2026
Visit: Panama, Bonaire, Aruba, Curacao, Trinidad and Tobago
Bonus Onboard Credit
Exclusive Savings
Inside
$986
Oceanview
$1,119
Balcony
$1,638
Suite
$1,811
From
US$986
Save 535
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ships: Grandeur of the Seas, Serenade of the Seas
Departures: Mar 2026 to Apr 2028
Visit: Panama, Colombia, Curacao, Aruba
Bonus Onboard Credit
Exclusive Savings
Inside
$797
Oceanview
$907
Balcony
$1,253
Suite
$1,316
From
US$797
Save 717
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: May 2026 to Apr 2028
Visit: Panama, Colombia, Aruba, Curacao
Bonus Onboard Credit
Exclusive Savings
Inside
$674
Oceanview
$739
Balcony
$1,014
Suite
$1,107
From
US$674
Save 703
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Mar 2027 to Mar 2027
Visit: Panama, Colombia, Curacao, Bonaire, Aruba
Bonus Onboard Credit
Exclusive Savings
Inside
$884
Oceanview
$1,005
Balcony
$1,434
Suite
$1,464
From
US$884
Save 531
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2028 to Apr 2028
Visit: Panama, Colombia, Curacao, Aruba
Bonus Onboard Credit
Exclusive Savings
Inside
$839
Oceanview
$949
Balcony
$1,329
Suite
$1,348
From
US$839
Save 542
Per Person
View Trip
8 Day Colon To San Juan Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to San Juan
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 24 April 2027
Visit: Panama, Saint Vincent, Saint Lucia, Antigua and Barbuda, Virgin Islands, Puerto Rico
Bonus Onboard Credit
Exclusive Savings
Inside
$618
Oceanview
$669
Balcony
$1,168
Suite
$1,268
From
US$618
Save 375
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 28 March 2026
Visit: Panama, Colombia, Aruba, Bonaire
Exclusive Savings
Inside
$1,258
Oceanview
$1,238
Balcony
$1,329
Suite
$1,728
From
US$1,238
Save 649
Per Person
View Trip
8 Day Southern Caribbean Holiday Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 19 December 2026
Visit: Panama, Colombia, Aruba, Bonaire
Bonus Onboard Credit
Exclusive Savings
Inside
$954
Oceanview
$984
Balcony
$1,537
Suite
$1,707
From
US$954
Save 528
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 18 March 2028
Visit: Panama, Colombia, Curacao, Aruba
Bonus Onboard Credit
Exclusive Savings
Inside
$919
Oceanview
$1,049
Balcony
$1,469
Suite
$1,499
From
US$919
Save 508
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 10 April 2027
Visit: Panama, Colombia, Aruba, Bonaire, Curacao
Bonus Onboard Credit
Exclusive Savings
Inside
$908
Oceanview
$1,037
Balcony
$1,477
Suite
$1,507
From
US$908
Save 501
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 30 January 2027
Visit: Panama, Colombia, Curacao, Aruba, Bonaire
Bonus Onboard Credit
Exclusive Savings
Inside
$828
Oceanview
$942
Balcony
$1,344
Suite
$1,328
From
US$828
Save 467
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ships: Grandeur of the Seas, Serenade of the Seas
Departures: Mar 2026 to Jan 2028
Visit: Panama, Colombia, Aruba, Curacao
Bonus Onboard Credit
Exclusive Savings
Inside
$861
Oceanview
$981
Balcony
$1,163
Suite
$1,390
From
US$861
Save 546
Per Person
View Trip
2 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

2 Days (1 Nights) Colon to Cartagena
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 18 April 2026
Visit: Panama, Colombia
Exclusive Savings
Inside
$101
Oceanview
$120
Balcony
$133
Suite
$183
From
US$101
Save 109
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Feb 2026 to Feb 2026
Visit: Panama, Colombia, Bonaire, Aruba
Exclusive Savings
Inside
$1,278
Oceanview
$1,278
Balcony
$1,328
Suite
$1,418
From
US$1,278
Save 666
Per Person
View Trip
11 Day Panama Canal Westward Cruise with Royal Caribbean
Cruise

11 Days (10 Nights) Colon to Los Angeles
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 25 April 2026
Visit: Panama, Costa Rica, Mexico, USA
Exclusive Savings
Inside
$783
Oceanview
$895
Balcony
$1,742
Suite
$3,617
From
US$783
Save 222
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 March 2026
Visit: Panama, Colombia, Aruba, Curacao
Exclusive Savings
Inside
$1,052
Oceanview
$1,052
Balcony
$1,152
Suite
$1,862
From
US$1,052
Save 567
Per Person
View Trip
Results: 18 results

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