Panama Cruises

Are you looking for a cruise to Panama? Choose from 43 unique cruise itineraries to Panama, departing from Cartagena, Colon, Fort Lauderdale, Fuerte Amador, Lima and more. March is the most popular month to cruise to Panama and we have over 53 departures available from eleven of the world's leading cruise lines.
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7 Days
20 Days
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$1,300pp
$20,670pp
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43 Cruises (53 Cruise Departures)
Cruise

12 Days (11 Nights) Panama City to San Jose
Operated By: Tauck
Departure: 18 January 2025
Trip Styles: Group, Cruise
Countries Visited: Panama, Costa Rica
From 14,250
Cruise

12 Days (11 Nights) San Jose to Panama City
Operated By: Tauck
Departures: Jan 2025 to Jan 2025
Trip Styles: Group, Cruise
Countries Visited: Costa Rica, Panama
From 13,640
Cruise

8 Days (7 Nights) Lima to Panama City
Cruise Line: Silversea
Ship: Silver Ray
Departure: 04 January 2025
Countries Visited: Ecuador, Panama, Peru
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$6,435
From 6,435
Cruise

13 Days (12 Nights) Colon to Lima
Cruise Line: Hurtigruten
Departure: 07 October 2024
Countries Visited: Panama, Ecuador, Peru
INSIDE
-
OCEANVIEW
$10,325
BALCONY
$11,121
SUITE
$12,293
From 10,325
Tour + Cruise

14 Days Colon to Lima
Operated By: Hurtigruten
Ship: MS Fram
Departure: 06 October 2024
Countries Visited: Panama, Ecuador, Peru
INSIDE
$10,084
OCEANVIEW
$10,812
BALCONY
-
SUITE
$12,377
From 10,084
Cruise

8 Days (7 Nights) Fuerte Amador to Lima
Cruise Line: Silversea
Ship: Silver Nova
Departure: 24 March 2024
Countries Visited: Ecuador, Panama, Peru
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$11,187
From 11,187
Cruise

8 Days (7 Nights) Panama City to Miami
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 24 May 2024
Countries Visited: Panama, Colombia, USA
Exclusive DealThe Total Luxury Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$5,341
SUITE
$6,519
From 5,341
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Departure: 10 March 2024
Countries Visited: Colombia, Aruba, Curacao, Panama
Exclusive Deal
INSIDE
$1,646
OCEANVIEW
$1,789
BALCONY
$2,484
SUITE
$2,442
Save 669
From 1,588
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Departure: 16 March 2024
Countries Visited: Panama, Colombia, Curacao, Aruba
Exclusive Deal
INSIDE
$1,853
OCEANVIEW
$1,956
BALCONY
$2,473
SUITE
$2,396
Save 1,187
From 1,853
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Departure: 17 March 2024
Countries Visited: Colombia, Curacao, Aruba, Panama
Exclusive Deal
INSIDE
$1,755
OCEANVIEW
$1,865
BALCONY
$2,013
SUITE
$2,510
Save 684
From 1,615
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Departure: 09 March 2024
Countries Visited: Panama, Colombia, Aruba, Curacao
Exclusive Deal
INSIDE
$1,540
OCEANVIEW
$1,663
BALCONY
$2,351
SUITE
$2,499
Save 620
From 1,509
Cruise

10 Days (9 Nights) Lima to Cartagena
Cruise Line: Silversea
Ship: Silver Nova
Departure: 31 March 2024
Countries Visited: Colombia, Ecuador, Panama, Peru
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$8,316
From 8,316
Cruise

10 Days (9 Nights) Panama City to Fort Lauderdale
Cruise Line: Silversea
Ship: Silver Ray
Departure: 11 January 2025
Countries Visited: Aruba, Colombia, Panama, USA
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$7,920
From 7,920
Cruise

9 Days (8 Nights) Cartagena to Lima
Cruise Line: Silversea
Ship: Silver Ray
Departure: 27 December 2024
Countries Visited: Colombia, Ecuador, Panama, Peru
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$11,385
From 11,385
Cruise

15 Days (14 Nights) Colon to Valparaiso
Cruise Line: Hurtigruten
Departures: Oct 2024 to Oct 2024
Countries Visited: Panama, Ecuador, Peru, Chile
INSIDE
$6,508
OCEANVIEW
$7,422
BALCONY
$8,832
SUITE
$10,609
From 6,508
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Departure: 24 March 2024
Countries Visited: Colombia, Curacao, Bonaire, Aruba (+1 more), Panama
Exclusive Deal
INSIDE
$2,653
OCEANVIEW
$2,667
BALCONY
$4,181
SUITE
$3,845
Save 1,131
From 2,622
Cruise
 (1)

8 Days (7 Nights) Colon to Fort Lauderdale
Cruise Line: Royal Caribbean
Departure: 13 April 2024
Countries Visited: Panama, Colombia, Aruba, Curacao (+1 more), USA
Exclusive Deal
INSIDE
$1,372
OCEANVIEW
$1,506
BALCONY
-
SUITE
$3,790
Save 496
From 1,355
Cruise
 (1)

7 Days (6 Nights) Cartagena to Colon
Cruise Line: Royal Caribbean
Departure: 07 April 2024
Countries Visited: Colombia, Curacao, Bonaire, Aruba (+1 more), Panama
Exclusive Deal
INSIDE
$1,785
OCEANVIEW
$1,833
BALCONY
$3,259
SUITE
$3,257
Save 771
From 1,775
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Departure: 30 March 2024
Countries Visited: Panama, Colombia, Aruba, Bonaire (+1 more), Curacao
Exclusive Deal
INSIDE
$2,118
OCEANVIEW
$2,692
BALCONY
$2,820
SUITE
$3,105
Save 1,354
From 2,118
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Departures: Mar 2024 to Apr 2024
Countries Visited: Panama, Colombia, Curacao, Bonaire (+1 more), Aruba
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$4,266
SUITE
$4,121
Save 3,017
From 4,121
Cruise
 (3)

19 Days (18 Nights) Los Angeles to Santiago
Cruise Line: Princess
Departure: 01 December 2024
Countries Visited: USA, Mexico, Panama, Peru (+1 more), Chile
INSIDE
$2,522
OCEANVIEW
-
BALCONY
$3,098
SUITE
$4,562
From 2,522
Cruise
 (2)

16 Days (15 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Departure: 09 May 2024
Countries Visited: USA, Mexico, Costa Rica, Panama (+1 more), Colombia
INSIDE
$2,647
OCEANVIEW
$2,747
BALCONY
$4,092
SUITE
$4,147
From 2,647
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Departure: 31 March 2024
Countries Visited: Colombia, Aruba, Bonaire, Curacao (+1 more), Panama
Exclusive Deal
INSIDE
$2,478
OCEANVIEW
$2,553
BALCONY
$3,822
SUITE
$3,868
Save 1,022
From 2,399
Cruise

11 Days (10 Nights) Panama City to Los Angeles
Cruise Line: Regent Seven Seas
Departure: 15 January 2026
Countries Visited: Panama, Costa Rica, Nicaragua, Mexico (+1 more), USA
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$9,480
SUITE
$9,995
Save 6,280
From 9,480
Cruise

16 Days (15 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Departures: Mar 2024 to Mar 2024
Countries Visited: USA, Colombia, Panama, Costa Rica (+1 more), Mexico
INSIDE
$2,787
OCEANVIEW
$3,054
BALCONY
$5,904
SUITE
$6,825
From 2,787
Cruise

10 Days (9 Nights) Miami to Panama City
Departure: 02 December 2024
Countries Visited: USA, Dominican Republic, Curacao, Aruba (+1 more), Panama
INSIDE
$2,082
OCEANVIEW
$2,417
BALCONY
$3,636
SUITE
$3,788
From 2,082
CruiseFlights Included

19 Days (18 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Silversea
Departure: 09 May 2025
Countries Visited: USA, Mexico, Costa Rica, Panama (+1 more), Colombia
Door-to-Door Upgrade OptionDoor-to-Door Economy Class Included
INSIDE
-
OCEANVIEW
$9,157
BALCONY
$11,632
SUITE
$23,463
Save 1,593
From 9,157
Cruise

18 Days (17 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Viking Cruises
Departures: Oct 2024 to Dec 2024
Countries Visited: USA, Mexico, Colombia, Panama (+1 more), Costa Rica
Explorer Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$11,083
SUITE
$20,785
Save 1,112
From 11,083
Cruise

18 Days (17 Nights) New York to San Francisco
Cruise Line: Cunard
Ship: Queen Anne
Departure: 18 January 2025
Countries Visited: USA, Aruba, Panama, Guatemala (+1 more), Mexico
INSIDE
$4,678
OCEANVIEW
$6,321
BALCONY
$7,836
SUITE
$15,696
From 4,678
Cruise

20 Days (19 Nights) Santiago to New York
Cruise Line: Viking Cruises
Departures: Mar 2026 to Mar 2026
Countries Visited: Chile, Peru, Panama, Jamaica (+1 more), Bahamas
Explorer Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$17,815
SUITE
$25,735
Save 1,180
From 17,815
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