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Cruises from Colon

Choose from 20 unique cruises starting in Colon, and traveling to Fort-de-France, Lima, Puntarenas and San Juan. January and April are the most popular months to join a cruise from Colon and you can select from 68 departures available from two leading cruise lines.
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20 Cruises (68 Departures)
20 Cruises (68 Departures)
Departures
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Duration
8 Days
13 Days
Countries Visited
End City
Ship Features
Operators
Price
$500pp
$19,970pp
Countries
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8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Aug 2026 to Apr 2028
Visits: Panama, Colombia, Aruba, Curacao
Exclusive Savings
Inside
$728
Oceanview
$811
Balcony
$1,035
Suite
$1,351
From (Per Person)
US$728
Save 1,118
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 10 April 2027
Visits: Panama, Colombia, Aruba, Bonaire, Curacao
Exclusive Savings
Inside
$1,279
Oceanview
$1,543
Balcony
$2,182
Suite
$2,162
From (Per Person)
US$1,279
Save 661
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Apr 2028
Visits: Panama, Colombia, Curacao, Aruba
Exclusive Savings
Inside
$888
Oceanview
$997
Balcony
$1,396
Suite
$1,400
From (Per Person)
US$888
Save 819
Per Person
View Trip
11 Day Panama, Colombia & Caribbean Islands with Ponant
Cruise
 (1)

11 Days (10 Nights) Colon to Fort-de-France
Cruise Line: Ponant
Ship: Le Bellot
Departure: 08 April 2027
Visits: Panama, Colombia, Holland, Saint Lucia, Guadeloupe, Martinique
Balcony
$8,700
Suite
$12,340
From (Per Person)
US$8,700
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 18 March 2028
Visits: Panama, Colombia, Curacao, Aruba
Exclusive Savings
Inside
$966
Oceanview
$1,106
Balcony
$1,549
Suite
$1,549
From (Per Person)
US$966
Save 528
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2028 to Apr 2028
Visits: Panama, Colombia, Curacao, Aruba
Exclusive Savings
Inside
$886
Oceanview
$996
Balcony
$1,399
Suite
$1,398
From (Per Person)
US$886
Save 567
Per Person
View Trip
8 Day Colon To San Juan Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to San Juan
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 24 April 2027
Visits: Panama, Saint Vincent, Saint Lucia, Antigua and Barbuda, Virgin Islands, Puerto Rico
Exclusive Savings
Inside
$515
Oceanview
$566
Balcony
$1,058
Suite
$1,308
From (Per Person)
US$515
Save 331
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Sep 2026 to Apr 2028
Visits: Panama, Colombia, Bonaire, Aruba, Curacao
Exclusive Savings
Inside
$1,003
Oceanview
$1,003
Balcony
$1,623
Suite
$1,643
From (Per Person)
US$1,003
Save 613
Per Person
View Trip
11 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

11 Days (10 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 14 November 2026
Visits: Panama, Bonaire, Aruba, Curacao, Trinidad and Tobago
Exclusive Savings
Inside
$1,079
Oceanview
$981
Balcony
-
Suite
$2,860
From (Per Person)
US$981
Save 701
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (1)

8 Days (7 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Nov 2026 to Dec 2027
Visits: Panama, Costa Rica
Balcony
$5,700
Suite
$9,450
From (Per Person)
US$5,700
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 13 February 2027
Visits: Panama, Colombia, Aruba, Bonaire
Exclusive Savings
Inside
$835
Oceanview
$875
Balcony
$1,488
Suite
$2,296
From (Per Person)
US$835
Save 477
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (2)

8 Days (7 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 15 January 2027
Visits: Panama, Costa Rica
Balcony
$7,590
Suite
$11,000
From (Per Person)
US$7,590
Per Person
View Trip
13 Day Panama, Colombia & Caribbean Islands with Ponant
Cruise
 (1)

13 Days (12 Nights) Colon to Fort-de-France
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville
Departures: Mar 2028 to Apr 2028
Visits: Panama, Colombia, Holland, Saint Vincent, Saint Lucia, Guadeloupe, Martinique
Balcony
$8,260
Suite
$12,780
From (Per Person)
US$8,260
Per Person
View Trip
11 Day Panama, Colombia & Caribbean Islands with Ponant
Cruise
 (2)

11 Days (10 Nights) Colon to Fort-de-France
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 12 March 2027
Visits: Panama, Colombia, Bonaire, Saint Vincent, Saint Lucia, Guadeloupe, Martinique
Balcony
$9,150
Suite
$13,000
From (Per Person)
US$9,150
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Mar 2027
Visits: Panama, Colombia, Curacao, Bonaire, Aruba
Exclusive Savings
Inside
$896
Oceanview
$1,010
Balcony
$1,829
Suite
$1,849
From (Per Person)
US$896
Save 636
Per Person
View Trip
8 Day Southern Caribbean Holiday Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 19 December 2026
Visits: Panama, Colombia, Aruba, Bonaire
Exclusive Savings
Inside
$1,132
Oceanview
$1,232
Balcony
-
Suite
$2,047
From (Per Person)
US$1,132
Save 640
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 30 January 2027
Visits: Panama, Colombia, Curacao, Aruba, Bonaire
Exclusive Savings
Inside
$1,110
Oceanview
$1,161
Balcony
$1,743
Suite
$1,943
From (Per Person)
US$1,110
Save 588
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 08 January 2028
Visits: Panama, Colombia, Aruba, Curacao
Exclusive Savings
Inside
$908
Oceanview
$1,038
Balcony
$1,441
Suite
$1,440
From (Per Person)
US$908
Save 503
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Nov 2026 to Dec 2027
Visits: Panama, Costa Rica
Balcony
$8,140
Suite
$13,490
From (Per Person)
US$8,140
Per Person
View Trip
11 Day From Panama’s Wild Beauty to Peruvian Shores with Ponant
Cruise

11 Days (10 Nights) Colon to Lima
Cruise Line: Ponant
Ship: L'Austral
Departure: 20 October 2026
Visits: Panama, Peru
Oceanview
$6,600
Balcony
$7,110
Suite
$13,160
From (Per Person)
US$6,600
Per Person
View Trip
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