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2 Week Panama Cruises

Looking to discover the best of Panama on a 2 week cruise? Then choose from our range of unique cruise itineraries with two leading cruise lines that explore Panama. March, October and January are the most popular months to travel to Panama and we have 4 cruise departures available.
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3 Cruises (4 Departures)
3 Cruises (4 Departures)
Departures
Start & End Cities
Operators
Price
$11,300pp
$20,390pp
Countries
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14 Day World Cruise: Panama Canal & South American Explorer with Seabourn
Cruise
 (1)

14 Days (13 Nights) Miami to Lima
Operator: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2029
Visits: USA, Colombia, Panama, Ecuador, Peru
Exclusive Savings
Oceanview
$11,394
Balcony
$13,844
Suite
$23,938
From (Per Person)
A$11,394
Save 205
Per Person
View Trip
14 Day Ancient Kingdoms and Natural Treasures: Chile to Panama with Scenic
New ReleaseCruise

14 Days (13 Nights) Santiago to Panama City
Operator: Scenic
Ship: Scenic Eclipse II
Departure: 21 March 2027
Visits: Chile, Peru, Ecuador, Colombia, Panama
Exclusive Savings
Balcony
$12,533
Suite
$17,712
From (Per Person)
A$12,533
Save 4,212
Per Person
View Trip
14 Day Ancient Kingdoms and Natural Treasures: Panama to Chile with Scenic
New ReleaseCruise

14 Days (13 Nights) Panama City to Santiago
Operator: Scenic
Ships: Scenic Eclipse I
Departures: Oct 2027 to Oct 2028
Visits: Panama, Colombia, Ecuador, Peru, Chile
Exclusive Savings
Balcony
$13,769
Suite
$18,649
From (Per Person)
A$13,769
Save 6,226
Per Person
View Trip
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South & Central America Cruises

Central America Cruises South America Cruises Mexico Cruises Galapagos Cruises Bermunda Cruises Bahamas Cruises Caribbean Cruises Amazon Cruises Patagonia Cruises Cape Horn Cruises Falkland Island Cruises Panama Cruises

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Trip Lengths

10 Day 2 Week 3 Week 7 Day

Departure Months

March October January

Cities

Colon Panama City

Routes

Colon to Colon Miami to Panama City Panama City to Miami

Country Routes

Panama to USA USA to Panama

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

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