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2 Week Panama Cruises

Looking to discover the best of Panama on a 2 week cruise? Then choose from our range of unique cruise itineraries with two leading cruise lines that explore Panama. March and October are the most popular months to travel to Panama and we have 3 cruise departures available.
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3 Cruises (3 Cruise Departures)
14 Day Chile, Peru & Panama Voyage with Azamara Cruises
Cruise
 (4)

14 Days (13 Nights) San Antonio to Panama City
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 02 March 2026
Visit: Chile, Peru, Panama
Azamara Always Included
Inside
-
Oceanview
-
Balcony
$2,359
Suite
-
From
US$2,359
Per Person
View Trip
14 Day Ancient Kingdoms and Natural Treasures: Chile to Panama with Scenic
New ReleaseCruise

14 Days (13 Nights) Santiago to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 21 March 2027
Visit: Chile, Peru, Ecuador, Colombia, Panama
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,233
Suite
$12,640
From
US$11,233
Save 14,957
Per Person
View Trip
14 Day Ancient Kingdoms and Natural Treasures: Panama to Chile with Scenic
New ReleaseCruise

14 Days (13 Nights) Panama City to Santiago
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 31 October 2027
Visit: Panama, Colombia, Ecuador, Peru, Chile
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,521
Suite
$16,995
From
US$14,521
Save 18,469
Per Person
View Trip
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South & Central America Cruises

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March October

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Cruise Lines Exploring South & Central America

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