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Cruises from Panama City to Miami

Are you looking for a cruise from Panama City to Miami? April and March are the most popular months to cruise between Panama City and Miami and there are 11 departures available from three of the world's leading cruise lines.
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15 Days
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$2,600pp
$24,898pp
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11 Cruises (11 Cruise Departures)
11 Day Panama & Pristine Isles with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 March 2027
Visit: Panama, Colombia, Aruba, Curacao, Jamaica, Bahamas, USA
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
$2,999
Oceanview
$3,725
Balcony
$4,404
Suite
$6,344
From
US$2,999
Save 2,999
Per Person
View Trip
11 Day Canal & Caribbean Discovery with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 27 January 2026
Visit: Panama, Colombia, Bonaire, Curacao, Aruba, Jamaica, USA
Your World Inclusions
Exclusive Savings
Inside
$3,239
Oceanview
$3,530
Balcony
-
Suite
-
From
US$3,239
Save 3,359
Per Person
View Trip
12 Day Panama Canal & Southern Caribbean Cruise: Cartagena, Aruba & Curacao with Azamara Cruises
Cruise
 (4)

12 Days (11 Nights) Panama City to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 15 March 2026
Visit: Panama, Colombia, Aruba, Curacao, Bonaire, Dominican Republic, USA
Azamara Always Included
Exclusive Savings
Inside
$2,644
Oceanview
-
Balcony
$5,234
Suite
-
From
US$2,644
Save 55
Per Person
View Trip
11 Day Canal & Coral Isles with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 24 April 2026
Visit: Panama, Colombia, Costa Rica, Honduras, Mexico, USA
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
$3,256
Balcony
-
Suite
$12,455
From
US$3,256
Save 4,542
Per Person
View Trip
11 Day Panama To Caribbean Joy with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 January 2027
Visit: Panama, Colombia, Aruba, Curacao, Jamaica, Cayman Islands, USA
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
$2,948
Oceanview
$3,724
Balcony
$4,403
Suite
$6,343
From
US$2,948
Save 3,050
Per Person
View Trip
15 Day Carnival Of Caribbean Colors with Regent Seven Seas
Cruise

15 Days (14 Nights) Panama City to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 31 March 2027
Visit: Panama, Colombia, Aruba, Curacao (+6 more), Bonaire, Grenada, Saint Lucia, Saint Barthelemy, Virgin Islands, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,807
Suite
$9,297
From
US$8,807
Save 16,091
Per Person
View Trip
11 Day Classic Canal & Tropics with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 04 April 2026
Visit: Panama, Colombia, Curacao, Aruba, Jamaica, Cayman Islands, USA
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$3,239
Oceanview
$3,627
Balcony
$5,082
Suite
$7,313
From
US$3,239
Save 3,359
Per Person
View Trip
11 Day Classic Canal & Tropics with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 16 January 2028
Visit: Panama, Colombia, Curacao, Aruba, Jamaica, Cayman Islands, USA
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$3,043
Oceanview
$4,013
Balcony
$4,789
Suite
$6,729
From
US$3,043
Save 3,155
Per Person
View Trip
11 Day Spanish Lullaby with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 March 2028
Visit: Panama, Costa Rica, Honduras, Guatemala, Mexico, USA
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$2,946
Oceanview
$3,916
Balcony
$4,692
Suite
$6,729
From
US$2,946
Save 3,052
Per Person
View Trip
13 Day Bon Bini Aruba with Regent Seven Seas
Cruise

13 Days (12 Nights) Panama City to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 14 March 2028
Visit: Panama, Colombia, Aruba, Curacao (+4 more), Grenada, Dominica, Virgin Islands, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,968
Suite
$8,360
From
US$7,968
Save 14,230
Per Person
View Trip
12 Day Crescent Beaches & Colorful Towns with Regent Seven Seas
Cruise

12 Days (11 Nights) Panama City to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 22 February 2027
Visit: Panama, Costa Rica, Honduras, Belize (+5 more), Guatemala, Mexico, Cayman Islands, Jamaica, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$7,772
From
US$7,772
Save 14,026
Per Person
View Trip
Results: 11 results

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