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South America Cruises with Regent Seven Seas

Join Regent Seven Seas on one of 15 cruises circumnavigating South America or venturing to the heart of the Amazon this season. January is the most popular month to begin your cruise and Regent Seven Seas have 15 cruises departing between December 2026 and March 2029.
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15 Cruises (15 Departures)
15 Cruises (15 Departures)
Departures
Duration
13 Days
43 Days
Start & End Cities
Ship Name
Price
$8,600pp
$62,860pp
Countries
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26 Day Ultimate Island Holiday with Regent Seven Seas
Cruise

26 Days (25 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 19 December 2027
Visits: USA, Virgin Islands, Saint Martin, Saint Barthelemy +14 more, Saint Kitts and Nevis, Antigua and Barbuda, Dominica, Saint Lucia, Barbados, Grenada, Aruba, Bonaire, Curacao, Colombia, Panama, Costa Rica, Jamaica, Cayman Islands
Exclusive Savings
Balcony
$24,405
Suite
$25,110
From (Per Person)
A$24,405
Save 2,425
Per Person
View Trip
17 Day Pearls, Palapas & Panama with Regent Seven Seas
Cruise

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 05 March 2029
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,930
Suite
$15,688
From (Per Person)
A$14,930
Save 8,930
Per Person
View Trip
29 Day Canal To Coral Reefs with Regent Seven Seas
Cruise

29 Days (28 Nights) Panama City to Tahiti
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 26 January 2027
Visits: Panama, Costa Rica, El Salvador, Guatemala, Mexico, USA, French Polynesia
Exclusive Savings
Balcony
-
Suite
$41,344
From (Per Person)
A$41,344
Save 2,756
Per Person
View Trip
43 Day Tides To Tahiti with Regent Seven Seas
Cruise

43 Days (42 Nights) Miami to Tahiti
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 12 January 2027
Visits: USA, Mexico, Belize, Honduras +8 more, Cayman Islands, Jamaica, Costa Rica, Colombia, Panama, El Salvador, Guatemala, French Polynesia
Exclusive Savings
Balcony
$26,545
Suite
$72,636
From (Per Person)
A$26,545
Save 36,315
Per Person
View Trip
13 Day Sapphire Sojourn with Regent Seven Seas
Cruise

13 Days (12 Nights) Los Angeles to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 10 February 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,555
Suite
$9,671
From (Per Person)
A$9,555
Save 8,575
Per Person
View Trip
17 Day Machu Picchu & Mayan Ruins with Regent Seven Seas
Cruise

17 Days (16 Nights) Lima to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 10 March 2027
Visits: Peru, Ecuador, Costa Rica, Panama +4 more, Honduras, Belize, Mexico, USA
Exclusive Savings
Balcony
$13,396
Suite
$13,954
From (Per Person)
A$13,396
Save 11,454
Per Person
View Trip
15 Day Exotic Coasts & Casco Viejo with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 23 February 2027
Visits: USA, Mexico, Belize, Honduras +5 more, Cayman Islands, Jamaica, Costa Rica, Colombia, Panama
Exclusive Savings
Balcony
$8,600
Suite
$9,377
From (Per Person)
A$8,600
Save 11,670
Per Person
View Trip
17 Day Panama Canal & Pacific Gems with Regent Seven Seas
Cruise

17 Days (16 Nights) Miami to Los Angeles
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 29 December 2026
Visits: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Balcony
$24,505
Suite
$25,406
From (Per Person)
A$24,505
Save 2,445
Per Person
View Trip
17 Day Tropical Transit with Regent Seven Seas
Cruise

17 Days (16 Nights) Miami to Los Angeles
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 07 February 2029
Visits: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,054
Suite
$15,813
From (Per Person)
A$15,054
Save 8,946
Per Person
View Trip
15 Day A Festive Passage with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 22 December 2027
Visits: USA, Mexico, Guatemala, Belize +5 more, Honduras, Costa Rica, Panama, Jamaica, Cayman Islands
Exclusive Savings
Balcony
$19,231
Suite
$20,211
From (Per Person)
A$19,231
Save 2,339
Per Person
View Trip
15 Day Holidays On The Canal with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 13 December 2028
Visits: USA, Mexico, Belize, Honduras +5 more, Costa Rica, Panama, Jamaica, Dominican Republic, Bahamas
Exclusive Savings
Balcony
$18,394
Suite
$20,354
From (Per Person)
A$18,394
Save 2,326
Per Person
View Trip
17 Day Holiday In Panama with Regent Seven Seas
Cruise

17 Days (16 Nights) Miami to San Francisco
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 20 December 2027
Visits: USA, Jamaica, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Balcony
-
Suite
$13,817
From (Per Person)
A$13,817
Save 10,193
Per Person
View Trip
15 Day Blue Seas & Pastel Towns with Regent Seven Seas
Cruise

15 Days (14 Nights) Galveston to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 28 December 2026
Visits: USA, Mexico, Belize, Guatemala +5 more, Honduras, Jamaica, Curacao, Aruba, Bonaire
Exclusive Savings
Balcony
$9,316
Suite
$10,227
From (Per Person)
A$9,316
Save 12,104
Per Person
View Trip
17 Day Ultimate Panama Canal Transit with Regent Seven Seas
Cruise

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 24 January 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Exclusive Savings
Balcony
$23,789
Suite
$25,279
From (Per Person)
A$23,789
Save 2,431
Per Person
View Trip
15 Day Tropical Treasures with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 12 January 2027
Visits: USA, Mexico, Belize, Honduras +5 more, Cayman Islands, Jamaica, Costa Rica, Colombia, Panama
Exclusive Savings
Balcony
$12,107
Suite
$12,612
From (Per Person)
A$12,107
Save 15,363
Per Person
View Trip
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