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South America Cruises with Regent Seven Seas

Join Regent Seven Seas on one of 16 cruises circumnavigating South America or venturing to the heart of the Amazon this season. January is the most popular month to begin your cruise and Regent Seven Seas have 16 cruises departing between December 2026 and March 2029.
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Departures
Duration
13 Days
128 Days
Start & End Cities
Ship Name
Price
$10,100pp
$176,390pp
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16 Cruises (16 Cruise Departures)
15 Day A Festive Passage with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 22 December 2027
Visit: USA, Mexico, Guatemala, Belize (+5 more), Honduras, Costa Rica, Panama, Jamaica, Cayman Islands
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$18,163
Suite
$19,457
From
A$18,163
Save 2,317
Per Person
View Trip
128 Day Navigate The World with Regent Seven Seas
Cruise

128 Days (127 Nights) Miami to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 11 January 2027
Visit: USA, Mexico, Belize, Honduras (+32 more), Cayman Islands, Jamaica, Costa Rica, Colombia, Panama, El Salvador, Guatemala, French Polynesia, American Samoa, Samoa, Fiji, Vanuatu, New Caledonia, Australia, Indonesia, Singapore, Malaysia, Thailand, Sri Lanka, Maldives, India, Oman, United Arab Emirates, Qatar, Saudi Arabia, Egypt, Jordan, Israel, Cyprus, Greece, Turkey, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$171,222
Suite
$181,179
From
A$171,222
Save 5,168
Per Person
View Trip
17 Day Machu Picchu & Mayan Ruins with Regent Seven Seas
Cruise

17 Days (16 Nights) Lima to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 10 March 2027
Visit: Peru, Ecuador, Costa Rica, Panama (+4 more), Honduras, Belize, Mexico, USA
Exquisite Escapes
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,139
Suite
$14,141
From
A$13,139
Save 10,251
Per Person
View Trip
29 Day Canal To Coral Reefs with Regent Seven Seas
Cruise

29 Days (28 Nights) Panama City to Tahiti
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 26 January 2027
Visit: Panama, Costa Rica, El Salvador, Guatemala, Mexico, USA, French Polynesia
Exquisite Escapes
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$19,212
Suite
$19,974
From
A$19,212
Save 17,268
Per Person
View Trip
13 Day Sapphire Sojourn with Regent Seven Seas
Cruise

13 Days (12 Nights) Los Angeles to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 10 February 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,959
Suite
$15,429
From
A$14,959
Save 2,271
Per Person
View Trip
15 Day Tropical Treasures with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 12 January 2027
Visit: USA, Mexico, Belize, Honduras (+5 more), Cayman Islands, Jamaica, Costa Rica, Colombia, Panama
Exquisite Escapes
Single Supplement Special
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,476
Suite
$16,244
From
A$15,476
Save 11,174
Per Person
View Trip
43 Day Tides To Tahiti with Regent Seven Seas
Cruise

43 Days (42 Nights) Miami to Tahiti
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 12 January 2027
Visit: USA, Mexico, Belize, Honduras (+8 more), Cayman Islands, Jamaica, Costa Rica, Colombia, Panama, El Salvador, Guatemala, French Polynesia
Exquisite Escapes
Single Supplement Special
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$31,327
Suite
$32,617
From
A$31,327
Save 28,013
Per Person
View Trip
17 Day Tropical Transit with Regent Seven Seas
Cruise

17 Days (16 Nights) Miami to Los Angeles
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 07 February 2029
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,054
Suite
$15,813
From
A$15,054
Save 8,946
Per Person
View Trip
17 Day Ultimate Panama Canal Transit with Regent Seven Seas
Cruise

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 24 January 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$23,563
Suite
$24,729
From
A$23,563
Save 2,427
Per Person
View Trip
17 Day Pearls, Palapas & Panama with Regent Seven Seas
Cruise

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 05 March 2029
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,930
Suite
$15,688
From
A$14,930
Save 8,930
Per Person
View Trip
15 Day Exotic Coasts & Casco Viejo with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 23 February 2027
Visit: USA, Mexico, Belize, Honduras (+5 more), Cayman Islands, Jamaica, Costa Rica, Colombia, Panama
Single Supplement Special
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,583
Suite
$18,474
From
A$17,583
Save 2,307
Per Person
View Trip
15 Day Blue Seas & Pastel Towns with Regent Seven Seas
Cruise

15 Days (14 Nights) Galveston to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 28 December 2026
Visit: USA, Mexico, Belize, Guatemala (+5 more), Honduras, Jamaica, Curacao, Aruba, Bonaire
Exquisite Escapes
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,163
Suite
$11,288
From
A$10,163
Save 10,467
Per Person
View Trip
17 Day Holiday In Panama with Regent Seven Seas
Cruise

17 Days (16 Nights) Miami to San Francisco
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 20 December 2027
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$20,605
From
A$20,605
Save 2,355
Per Person
View Trip
17 Day Panama Canal & Pacific Gems with Regent Seven Seas
Cruise

17 Days (16 Nights) Miami to Los Angeles
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 29 December 2026
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$24,505
Suite
$25,406
From
A$24,505
Save 2,445
Per Person
View Trip
15 Day Holidays On The Canal with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 13 December 2028
Visit: USA, Mexico, Belize, Honduras (+5 more), Costa Rica, Panama, Jamaica, Dominican Republic, Bahamas
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$18,394
Suite
$20,354
From
A$18,394
Save 2,326
Per Person
View Trip
26 Day Ultimate Island Holiday with Regent Seven Seas
Cruise

26 Days (25 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 19 December 2027
Visit: USA, Virgin Islands, Saint Martin, Saint Barthelemy (+14 more), Saint Kitts and Nevis, Antigua and Barbuda, Dominica, Saint Lucia, Barbados, Grenada, Aruba, Bonaire, Curacao, Colombia, Panama, Costa Rica, Jamaica, Cayman Islands
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$26,169
Suite
$26,786
From
A$26,169
Save 2,461
Per Person
View Trip
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