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South America Cruises with Regent Seven Seas

Join Regent Seven Seas on one of 12 cruises circumnavigating South America or venturing to the heart of the Amazon this season. January is the most popular month to begin your cruise and Regent Seven Seas have 12 cruises departing between December 2026 and January 2028.
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Departures
Duration
13 Days
66 Days
Start & End Cities
Ship Name
Price
$8,900pp
$135,098pp
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12 Cruises (12 Cruise Departures)
17 Day Ultimate Panama Canal Transit with Regent Seven Seas
Cruise

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 24 January 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,970
Suite
$13,950
From
US$12,970
Save 19,628
Per Person
View Trip
17 Day Panama Canal & Pacific Gems with Regent Seven Seas
Cruise

17 Days (16 Nights) Miami to Los Angeles
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 29 December 2026
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,069
Suite
$13,657
From
US$13,069
Save 18,729
Per Person
View Trip
26 Day Ultimate Island Holiday with Regent Seven Seas
Cruise

26 Days (25 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 19 December 2027
Visit: USA, Virgin Islands, Saint Martin, Saint Barthelemy (+14 more), Saint Kitts and Nevis, Antigua and Barbuda, Dominica, Saint Lucia, Barbados, Grenada, Aruba, Bonaire, Curacao, Colombia, Panama, Costa Rica, Jamaica, Cayman Islands
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,313
Suite
$17,489
From
US$16,313
Save 25,885
Per Person
View Trip
15 Day Tropical Treasures with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 12 January 2027
Visit: USA, Mexico, Belize, Honduras (+5 more), Cayman Islands, Jamaica, Costa Rica, Colombia, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,774
Suite
$14,215
From
US$13,774
Save 20,624
Per Person
View Trip
29 Day Canal To Coral Reefs with Regent Seven Seas
Cruise

29 Days (28 Nights) Panama City to Tahiti
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 26 January 2027
Visit: Panama, Costa Rica, El Salvador, Guatemala, Mexico, USA, French Polynesia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$21,043
Suite
$22,219
From
US$21,043
Save 30,155
Per Person
View Trip
13 Day Sapphire Sojourn with Regent Seven Seas
Cruise

13 Days (12 Nights) Los Angeles to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 10 February 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,938
Suite
$9,281
From
US$8,938
Save 15,260
Per Person
View Trip
43 Day Tides To Tahiti with Regent Seven Seas
Cruise

43 Days (42 Nights) Miami to Tahiti
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 12 January 2027
Visit: USA, Mexico, Belize, Honduras (+8 more), Cayman Islands, Jamaica, Costa Rica, Colombia, Panama, El Salvador, Guatemala, French Polynesia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$33,739
Suite
$34,621
From
US$33,739
Save 50,059
Per Person
View Trip
17 Day Holiday In Panama with Regent Seven Seas
Cruise

17 Days (16 Nights) Miami to San Francisco
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 20 December 2027
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,036
Suite
$10,771
From
US$10,036
Save 17,362
Per Person
View Trip
15 Day A Festive Passage with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 22 December 2027
Visit: USA, Mexico, Guatemala, Belize (+5 more), Honduras, Costa Rica, Panama, Jamaica, Cayman Islands
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,245
Suite
$10,176
From
US$9,245
Save 16,553
Per Person
View Trip
66 Day Grand South America Mosaic with Regent Seven Seas
Cruise

66 Days (65 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 13 January 2028
Visit: USA, Cayman Islands, Jamaica, Colombia (+12 more), Costa Rica, Panama, Ecuador, Peru, Chile, Antarctica, Falkland Islands, Argentina, Uruguay, Brazil, Saint Lucia, Saint Kitts and Nevis
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$51,646
Suite
$53,214
From
US$51,646
Save 83,452
Per Person
View Trip
17 Day Machu Picchu & Mayan Ruins with Regent Seven Seas
Cruise

17 Days (16 Nights) Lima to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 10 March 2027
Visit: Peru, Ecuador, Costa Rica, Panama (+4 more), Honduras, Belize, Mexico, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,677
Suite
$13,755
From
US$12,677
Save 19,121
Per Person
View Trip
15 Day Exotic Coasts & Casco Viejo with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 23 February 2027
Visit: USA, Mexico, Belize, Honduras (+5 more), Cayman Islands, Jamaica, Costa Rica, Colombia, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,833
Suite
$10,274
From
US$9,833
Save 16,365
Per Person
View Trip
Results: 12 results

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