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Cruises From Panama City

Choose from 20 unique cruises starting in Panama City, and travelling to Bridgetown, Fort Lauderdale, Galveston, Los Angeles, Miami and more. December is the most popular month to join a cruise from Panama City and you can select from 23 departures available from eight leading cruise lines.
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Duration
10 Days
23 Days
End City
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$1,700pp
$25,170pp
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20 Cruises (23 Cruise Departures)
Cruise
 (6)

11 Days (10 Nights) Panama City to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Oct 2024 to Dec 2025
Countries Visited: Panama, Costa Rica, Honduras, Belize (+2 more), Mexico, USA
Companion Fly Free
INSIDE
-
OCEANVIEW
-
BALCONY
$5,589
SUITE
$9,795
Save (per person) 2,506
From (per person) 5,589
Cruise
 (1)

10 Days (9 Nights) Panama City to Miami
Cruise Line: Azamara Cruises
Departure: 13 December 2024
Countries Visited: Panama, Costa Rica, Honduras, Guatemala (+2 more), Mexico, USA
Circle Club Voyage
INSIDE
$1,923
OCEANVIEW
$2,012
BALCONY
$2,468
SUITE
-
From (per person) 1,923
Cruise
 (2)

12 Days (11 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Departure: 18 February 2025
Countries Visited: Panama, Colombia, Aruba, Curacao (+4 more), Bonaire, Jamaica, Bahamas, USA
Bonus SavingsExclusive Deal
INSIDE
$4,984
OCEANVIEW
$5,385
BALCONY
-
SUITE
$10,874
Save (per person) 2,586
From (per person) 4,984
Cruise
 (2)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Departure: 02 April 2025
Countries Visited: Panama, Colombia, Aruba, Curacao (+3 more), Bonaire, Jamaica, USA
Bonus SavingsExclusive Deal
INSIDE
$4,314
OCEANVIEW
$4,778
BALCONY
$6,854
SUITE
$9,135
Save (per person) 2,506
From (per person) 4,314
Cruise
 (1)

12 Days (11 Nights) Panama City to Miami
Cruise Line: Azamara Cruises
Departure: 15 March 2026
Countries Visited: Panama, Colombia, Aruba, Bonaire (+3 more), Curacao, Dominican Republic, USA
INSIDE
$4,853
OCEANVIEW
$6,070
BALCONY
$7,179
SUITE
$9,030
From (per person) 4,853
Cruise

14 Days (13 Nights) Panama City to New York
Cruise Line: Norwegian Cruise Line
Departure: 22 December 2025
Countries Visited: Panama, Colombia, Aruba, Curacao (+5 more), Saint Lucia, Saint Kitts and Nevis, Virgin Islands, Dominican Republic, USA
More At Sea Offer
INSIDE
$5,014
OCEANVIEW
$5,779
BALCONY
$7,691
SUITE
$8,838
From (per person) 5,014
Cruise

12 Days (11 Nights) Panama City to Galveston
Cruise Line: Norwegian Cruise Line
Departure: 26 January 2026
Countries Visited: Panama, Colombia, Jamaica, Cayman Islands (+4 more), Honduras, Belize, Mexico, USA
More At Sea Offer
INSIDE
$3,824
OCEANVIEW
$4,359
BALCONY
$5,736
SUITE
$6,241
From (per person) 3,824
Cruise

12 Days (11 Nights) Panama City to Miami
Cruise Line: Norwegian Cruise Line
Departure: 16 February 2026
Countries Visited: Panama, Colombia, Aruba, Saint Lucia (+4 more), Saint Kitts and Nevis, Virgin Islands, Dominican Republic, USA
More At Sea OfferExclusive Solo Offer
INSIDE
$3,788
OCEANVIEW
$4,324
BALCONY
$5,822
SUITE
$6,206
From (per person) 3,788
Cruise

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Departure: 24 April 2026
Countries Visited: Panama, Colombia, Costa Rica, Honduras (+2 more), Mexico, USA
Exclusive Deal
INSIDE
$4,483
OCEANVIEW
$4,938
BALCONY
$7,314
SUITE
$10,145
Save (per person) 2,027
From (per person) 4,483
Cruise

11 Days (10 Nights) Panama City to Tampa
Cruise Line: Norwegian Cruise Line
Departure: 19 January 2025
Countries Visited: Panama, Colombia, Jamaica, Cayman Islands (+4 more), Honduras, Belize, Mexico, USA
More At Sea Offer
INSIDE
$2,230
OCEANVIEW
$2,306
BALCONY
$4,064
SUITE
$4,187
From (per person) 2,230
Cruise

10 Days (9 Nights) Panama City to Miami
Cruise Line: Norwegian Cruise Line
Departure: 11 December 2024
Countries Visited: Panama, Costa Rica, Jamaica, Cayman Islands (+3 more), Mexico, Bahamas, USA
More At Sea OfferExclusive Solo Offer
INSIDE
$1,752
OCEANVIEW
$1,782
BALCONY
$1,874
SUITE
$1,981
From (per person) 1,752
Cruise

11 Days (10 Nights) Panama City to Los Angeles
Cruise Line: Regent Seven Seas
Departure: 15 January 2026
Countries Visited: Panama, Costa Rica, Nicaragua, Mexico (+1 more), USA
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,064
SUITE
$10,658
Save (per person) 6,286
From (per person) 10,064
New ReleaseCruise

10 Days (9 Nights) Panama City to Santiago
Cruise Line: Scenic
Departure: 26 October 2026
Countries Visited: Panama, Chile
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$8,311
SUITE
$10,746
Save (per person) 3,084
From (per person) 8,311
Cruise

12 Days (11 Nights) Panama City to Miami
Cruise Line: Norwegian Cruise Line
Departure: 09 February 2025
Countries Visited: Panama, Colombia, Aruba, Curacao (+4 more), Saint Kitts and Nevis, Virgin Islands, Dominican Republic, USA
More At Sea Offer
INSIDE
$2,729
OCEANVIEW
$2,805
BALCONY
$5,299
SUITE
$5,374
From (per person) 2,729
Cruise

23 Days (22 Nights) Panama City to Panama City
Cruise Line: Regent Seven Seas
Departure: 09 March 2027
Countries Visited: Panama, Aruba, Trinidad and Tobago, Brazil (+2 more), Grenada, Curacao
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$16,299
SUITE
$18,517
Save (per person) 8,871
From (per person) 16,299
Cruise

12 Days (11 Nights) Panama City to Los Angeles
Cruise Line: Silversea
Departure: 24 December 2024
Countries Visited: Panama, Costa Rica, Mexico, USA
Port-to-Port
INSIDE
-
OCEANVIEW
$7,623
BALCONY
$10,791
SUITE
$22,572
From (per person) 7,623
Cruise

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Departure: 04 April 2026
Countries Visited: Panama, Colombia, Curacao, Aruba (+3 more), Jamaica, Cayman Islands, USA
Exclusive Deal
INSIDE
$4,641
OCEANVIEW
$5,086
BALCONY
$7,462
SUITE
$10,293
Save (per person) 2,029
From (per person) 4,641
Cruise

11 Days (10 Nights) Panama City to Miami
Cruise Line: Norwegian Cruise Line
Departure: 10 November 2025
Countries Visited: Panama, Colombia, Jamaica, Cayman Islands (+4 more), Honduras, Belize, Mexico, USA
More At Sea OfferExclusive Solo Offer
INSIDE
$3,609
OCEANVIEW
$4,069
BALCONY
$5,291
SUITE
$5,675
From (per person) 3,609
Cruise

12 Days (11 Nights) Panama City to San Jose
Operated By: Tauck
Departure: 18 January 2025
Countries Visited: Panama, Costa Rica
From (per person) 14,250
New ReleaseCruise

12 Days (11 Nights) Panama City to Bridgetown
Cruise Line: Scenic
Departure: 13 April 2026
Countries Visited: Panama, Colombia, Aruba, Curacao (+2 more), Saint Vincent, Barbados
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$11,727
SUITE
$14,538
Save (per person) 3,618
From (per person) 11,727
Results: 20 results

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