Crescent Beaches & Colorful Towns

12 Days Panama City to Miami
Crescent Beaches & Colorful Towns
Crescent Beaches & Colorful Towns
Crescent Beaches & Colorful Towns
Cruising At Sea
Cruising At Sea
Cozumel
Cozumel
Isla De Roatan
Isla De Roatan
Santo Tomas De Castilla
Santo Tomas De Castilla
Miami
Miami
Panama City
Panama City
Harvest Caye
Harvest Caye
Montego Bay
Montego Bay
Puerto Limon
Puerto Limon
Montego Bay
Montego Bay
Regent Seven Seas
Cruise Operated By:
Regent Seven Seas
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Begin your journey in Panama City and cruise through to Miami onboard Seven Seas Prestige and enjoy exclusive savings and cruise inclusions with Regent Seven Seas and Global Journeys.
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Our Price From
A$15,626 per person
Price shown based on twin share
Save up to $7,674 per person
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Cruise Length
12 Days
Cruise Starts
Panama City
Cruise Ends
Miami
Departures
Cruise Ship
All-Inclusive Level
Passengers
822
Crew
630
Launched
2026
Cruise Code
CBCTPCMPR11.2

Itinerary

Departs: 17:00

Panama is a cosmopolitan, dynamic city, where the modern and the traditional come together to create a cheerful and relaxed atmosphere. Three main sections make up the city, the historical ruins of the 16th century called Panama Viejo, the 17th century Spanish Colonial Casco Viejo and the modern skyscraper city.

Top Things to Do in Panama City:

  • explore Portobelo National Park
  • watch ships pass through the Panama Canal
  • shop until you drop at the Duty-Free Zone
  • ride a vintage train on the Panama Railway

Arrives: 06:00 Departs: 18:00

The Panama Canal, a marvel of engineering, links the Atlantic and Pacific Oceans, facilitating global maritime trade. Stretching approximately 80km/50mi, this intricate waterway features three locks - Miraflores, Pedro Miguel, and Gatun - that elevate and lower vessels to overcome the variation in sea levels.

The Miraflores Locks' visitor center offers an insightful experience, allowing observers to witness massive ships navigating the locks. The Gatun Locks, a crucial part of the canal, showcase the impressive process of raising and lowering water levels to enable the passage of ships.

Traversing the Panama Canal provides a firsthand glimpse into the intricate operations that have shaped international shipping for over a century.

Arrives: 08:00 Departs: 18:00

This bustling city is home to extravagant open-air markets that buzz with commerce, fascinating architecture and historical museums. Beyond the city lies a land that features thick rainforests, meandering rivers, and a variety of exotic wildlife. Ships will dock at the cruise terminal.

Top Things to Do in Puerto Limon:

  • ride an aerial tram through the canopy of the Braulio Carrillo National Park
  • cruise the waters of the Tortuguero Canals
  • spot native animals in Cahuita National Park
  • visit the wildlife rescue centre

Evenings on board are filled with music and fun. Enjoy a rousing cabaret show, test your luck at the Casino, step onto the stage for karaoke or simply find a quiet place on deck to revel in the symphony of stars.

Arrives: 11:00 Departs: 18:00

Roatan, the largest of the Bay Islands of Honduras, is noted for its pristine coral reefs, beautiful beaches, lush tropical foliage, and friendly people. A diving paradise, there is easy access to the underwater marvel of the Caribbean’s largest coral reef. Ships will dock or anchor offshore in the town of Coxen Hole.

Top Things to Do on Roatan:

  • look for monkeys in Gumbalimba Park Nature Reserve
  • snorkel or scuba dive the reef
  • go deep sea fishing
  • go horseback riding on the beach

Arrives: 08:00 Departs: 17:00

Featuring an enchanting range of environments such as tropical rainforests, marshes and coral reefs, Harvest Caye offers both relaxation and adventure amid lush landscapes. This pristine mangrove-covered 75-acre private island is a gem in the crown of Belize’s natural resources. Ships will dock at this port.

Top Things to Do on Harvest Caye:

  • cruise the Monkey River
  • zip line across the island
  • snorkel the barrier reef
  • parasail the waters of the Caribbean Sea
  • discover the Mayan temple of Nim Li Punit

Arrives: 07:00 Departs: 13:00

Santo Tomas de Castilla is the Caribbeans gateway to Guatemala. It was originally settled in the 19th century by Belgian pioneers, today the streets are scattered with colonial buildings, a lasting clue to its European background. Ships will dock at this port.

Top Things to Do in Santo Tomas:

  • hike to the Las Escobas waterfalls
  • explore San Felipe Castle
  • visit the indigenous Q’eqchi village
  • travel by air to Tikal National Park, an ancient Mayan city site
  • explore Quirigua National Park

Arrives: 10:00 Departs: 16:00

Cozumel is the largest island in the Mexican Caribbean. Rich in history, Mayan vestiges and natural wonders, it is a true paradise in the middle of the sea with white beaches, beautiful sunsets and world famous for its coral reefs.

Top Things to Do in Cozumel:

  • visit the San Gervasio Mayan site
  • explore the Chankanaab National Park
  • visit the Museo de Cozumel
  • cross to the mainland and explore Tulum, Playa Del Carmen or Chichén Itza
  • spend the day at Xcaret Eco Park
  • snorkel one of Cozumel's famous reefs

Arrives: 11:00 Departs: 16:00

Georgetown, the capital of the Cayman Islands, serves as a vibrant hub of activity and culture. Located on Grand Cayman, it is known for its excellent duty-free shopping, ranging from luxury boutiques to local crafts. The city also boasts a rich maritime history, which can be explored in depth at the Cayman Islands National Museum.

Visitors arriving by cruise are welcomed by the picturesque harbour and its crystal-clear waters, ideal for snorkelling and diving. Just offshore, the famous Stingray City offers a unique opportunity to swim alongside and feed the friendly southern stingrays in their natural habitat.

Arrives: 07:00 Departs: 13:00

Montego Bay offers travellers a kaleidoscope of Jamaica's charms, from pristine beaches and tropical scenery to historic plantation houses. Stunning natural beauty and a unique society make Jamaica an unforgettable Caribbean port of call. Ships will dock at this port.

Top Things to Do in Montego Bay:

  • climb to the top of Dunn's River Falls
  • cruise Martha Brae River on a bamboo raft
  • visit Rose Hall Great House
  • relax on Doctor's Cave Beach
  • visit Mystic Mountain, Rainforest Adventures
  • go horseback riding in Sandy Bay

Arrives: 07:00

Known as the 'cruise capital of the world', Port Miami is is considered to be the world’s busiest cruise ship port. Whether arriving or departing, aboard your cruise liner you can take in the superb view of the Miami skyline.

This multicultural city where the sun rules supreme is more than just a cruise port. Palm-lined causeways stretch across luminous Biscayne Bay as Miami rises in a gleam of glass towers, Art Deco curves, and tropical colour. Along Ocean Drive in South Beach, pastel facades from the 1930s glow beneath the Florida sun, while nearby Little Havana hums with domino parks, cigar shops, and the aroma of Cuban coffee. Beyond the shoreline, calm waters, yacht marinas, and breezy promenades frame a city shaped by Caribbean rhythms and sunlit coastal glamour.

Note: Ship ports may not be located in the starting & ending cities listed. Port and transfer details will be provided in your travel documentation. The provided itinerary is for informational purposes only. Activities and sightseeing attractions listed may not be available or achievable within the time in port.

Life On Board

Seven Seas Prestige
Seven Seas Prestige

Unwind in all-balcony suites and beautifully designed social spaces that redefine comfort and luxury onboard the Seven Seas Prestige. Read more

Free Unlimited Shore Excursions
Free Unlimited Shore Excursions

Discover the world in depth with over 2,000 included shore excursions across iconic and off-the-beaten-track destinations. Read more

Culinary Arts Kitchen
Culinary Arts Kitchen

Dive into the flavours of each region with hands-on culinary experiences led by masterful onboard chefs. Read more

Relax on the Pool Deck
Relax on the Pool Deck

Soak up the sun by the pool or sip a handcrafted cocktail as you drift into relaxation. Read more

Experience the Regent Suite
Experience the Regent Suite

Step into a world of unrivalled elegance with Regent’s most spacious and luxurious suite — your private sanctuary at sea. Read more

Complimentary Speciality Restaurants
Complimentary Speciality Restaurants

Savour exquisite cuisine at a variety of complimentary speciality restaurants, crafted to delight every palate. Read more

Download Brochure

Regent Seven Seas Cruises (2025-27) Brochure

Regent Seven Seas Cruises (2025-27)

Step into an all-inclusive, ultra luxury experience that is Unrivaled at Sea. Explore more than 550 destinations around the world while enjoying the unrivaled space, elegance and comfort of the World’s Most Luxurious Fleet. We’ll tend to every detail of your journey from start to finish, so you can be pampered by the warm Heartfelt Hospitality delivered more by our incredible crew who not only care for you, but about you. Nobody Does It Better than Regent Seven Seas Cruises.

Dates & Pricing

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Sold Out
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From $15,626
From $15,952
Monday 22 Feb 2027 22 Feb 27 Panama City
Friday 05 Mar 2027 05 Mar 27 Miami
Details
Seven Seas Prestige
Exclusive Savings
Balcony
A$15,626
Save $7,674
Twin Share (Per Personpp)
Note
Tour & cruises prices are per person. Prices shown have savings applied, are subject to availability and may be withdrawn at any time without notice. Pricing and trip details are correct at this point in time, however are subject to confirmation at the time of booking and are subject to change by Regent Seven Seas. For cruise itineraries, cabin images are sourced from the cruise-line and should be treated as indicative only. Cabin inclusions, upholsteries and room layout may differ to the image(s) shown depending on the ship selected and your sailing dates.

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