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Guatemala Cruises

Are you looking for a cruise to Guatemala? Choose from 9 unique cruise itineraries to Guatemala, departing from Fort Lauderdale, Los Angeles, Miami and Panama City. April and January are the most popular months to cruise to Guatemala and we have over 9 departures available from four of the world's leading cruise lines.
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9 Cruises (9 Cruise Departures)
8 Day Sea, Sun & Salsa with Regent Seven Seas
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 20 November 2027
Visit: USA, Belize, Guatemala, Mexico
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,063
Suite
$5,259
From
US$5,063
Save 10,235
Per Person
View Trip
10 Day A Journey Through Sacred Cenotes & Hidden Mayan Pyramids with Explora Journeys
Cruise

10 Days (9 Nights) Miami to Miami
Cruise Line: Explora Journeys
Ship: Explora IV
Departure: 06 January 2028
Visit: USA, Mexico, Guatemala, Belize, Bahamas
A Suite Invitation
Inside
-
Oceanview
-
Balcony
$5,355
Suite
$6,230
From
US$5,355
Per Person
View Trip
9 Day A Journey Into Tropical Idylls & Mayan Mystery with Explora Journeys
Cruise

9 Days (8 Nights) Miami to Miami
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 05 December 2026
Visit: USA, Mexico, Guatemala, Belize, Honduras
A Suite Invitation
Inside
-
Oceanview
-
Balcony
$4,375
Suite
$4,970
From
US$4,375
Per Person
View Trip
12 Day A Journey Of Mayan Discovery & Mexican Exploration with Explora Journeys
Cruise

12 Days (11 Nights) Panama City to Los Angeles
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 22 April 2027
Visit: Panama, El Salvador, Guatemala, Mexico, USA
A Suite Invitation
Inside
-
Oceanview
-
Balcony
$6,940
Suite
$8,075
From
US$6,940
Per Person
View Trip
13 Day Sapphire Sojourn with Regent Seven Seas
Cruise

13 Days (12 Nights) Los Angeles to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 10 February 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,938
Suite
$9,281
From
US$8,938
Save 15,260
Per Person
View Trip
10 Day A Journey Of Enchanting Ancient History & Coastal Splendour with Explora Journeys
Cruise

10 Days (9 Nights) Miami to Miami
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 20 January 2027
Visit: USA, Jamaica, Guatemala, Honduras, Belize
A Suite Invitation
Inside
-
Oceanview
-
Balcony
$4,935
Suite
$5,565
From
US$4,935
Per Person
View Trip
15 Day Los Angeles To Miami with Cunard
Cruise

15 Days (14 Nights) Los Angeles to Miami
Cruise Line: Cunard
Ship: Queen Anne
Departure: 05 April 2026
Visit: USA, Guatemala, Panama, Curacao, Aruba
Inside
$1,689
Oceanview
-
Balcony
$3,559
Suite
$6,067
From
US$1,689
Per Person
View Trip
15 Day Panama Canal with Holland America
Cruise

15 Days (14 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Eurodam
Departure: 03 April 2027
Visit: USA, Colombia, Costa Rica, Guatemala, Mexico
Fare Saver
Inside
$2,209
Oceanview
$2,409
Balcony
$3,536
Suite
$6,133
From
US$2,209
Per Person
View Trip
16 Day Miami To Los Angeles with Cunard
Cruise

16 Days (15 Nights) Miami to Los Angeles
Cruise Line: Cunard
Ship: Queen Anne
Departure: 23 January 2028
Visit: USA, Colombia, Panama, Guatemala, Mexico
Inside
$3,729
Oceanview
$4,579
Balcony
$5,579
Suite
$10,434
From
US$3,729
Per Person
View Trip
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