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Panama Cruises Starting In February 2026, 2027 and 2028

If you're looking at joining a cruise to Panama in February 2026, 2027 or 2028, we have 17 unique cruise itineraries and 116 departures available, operated by six of the world's leading cruise lines departing in February.
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17 Cruises (116 Cruise Departures)
13 Day Costa Rica, Panama from the Pacific to the Atlantic via the Panama Canal with Emerald Cruises
New ReleaseCruise
 (3)

13 Days (12 Nights) San Jose to San Jose
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 10 February 2028
Visit: Costa Rica, Panama
Black Friday Sale
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$10,031
Balcony
-
Suite
$12,699
From
US$10,031
Save 12,959
Per Person
View Trip
8 Day Panama and Costa Rica by Sea: The Natural Wonders of Central America – with Smithsonian Journeys with Ponant
Cruise

8 Days (7 Nights) Puntarenas to Colon
Cruise Line: Ponant
Ships: Le Champlain, Le Laperouse
Departures: Feb 2026 to Feb 2027
Visit: Costa Rica, Panama
Inside
-
Oceanview
-
Balcony
$6,610
Suite
$11,060
From
US$6,610
Per Person
View Trip
8 Day Coastal Adventures: Costa Rica & Panama with Emerald Cruises
Cruise
 (3)

8 Days (7 Nights) San Jose to Panama City
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 22 February 2028
Visit: Costa Rica, Panama
Black Friday Sale
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$5,876
Balcony
-
Suite
$7,574
From
US$5,876
Save 8,614
Per Person
View Trip
8 Day Panama and Costa Rica by Sea: The Natural Wonders of Central America - with Smithsonian Journeys with Ponant
Cruise

8 Days (7 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ship: Le Champlain
Departure: 19 February 2026
Visit: Panama, Costa Rica
Inside
-
Oceanview
-
Balcony
$6,790
Suite
-
From
US$6,790
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise

8 Days (7 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ships: Le Bellot, Le Dumont d’Urville, Le Laperouse
Departures: Dec 2025 to Feb 2027
Visit: Panama, Costa Rica
Inside
-
Oceanview
-
Balcony
$5,630
Suite
$9,540
From
US$5,630
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Jan 2026 to Feb 2026
Visit: Panama, Colombia, Bonaire, Aruba
Exclusive Savings
Inside
$823
Oceanview
$853
Balcony
$1,023
Suite
$1,413
From
US$823
Save 729
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: May 2026 to Apr 2027
Visit: Panama, Colombia, Aruba, Curacao
Bonus Onboard Credit
Exclusive Savings
Inside
$678
Oceanview
$746
Balcony
$1,108
Suite
$1,256
From
US$678
Save 565
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Feb 2026 to Apr 2026
Visit: Colombia, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,095
Oceanview
$1,015
Balcony
$1,159
Suite
$1,695
From
US$1,015
Save 694
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Jan 2026 to Mar 2026
Visit: Colombia, Bonaire, Aruba, Panama
Exclusive Savings
Inside
$1,079
Oceanview
$1,060
Balcony
$1,150
Suite
$1,439
From
US$1,060
Save 966
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: May 2026 to Apr 2027
Visit: Colombia, Aruba, Curacao, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$770
Oceanview
$880
Balcony
$1,240
Suite
$1,326
From
US$770
Save 631
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Feb 2026 to Apr 2026
Visit: Panama, Colombia, Aruba, Curacao
Exclusive Savings
Inside
$827
Oceanview
$878
Balcony
$998
Suite
$1,928
From
US$827
Save 626
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ships: Grandeur of the Seas, Serenade of the Seas
Departures: Jan 2026 to Feb 2027
Visit: Panama, Colombia, Aruba, Bonaire
Bonus Onboard Credit
Exclusive Savings
Inside
$773
Oceanview
$883
Balcony
$1,006
Suite
$1,358
From
US$773
Save 649
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ships: Grandeur of the Seas, Serenade of the Seas
Departures: Jan 2026 to Feb 2027
Visit: Colombia, Aruba, Bonaire, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$814
Oceanview
$934
Balcony
$1,162
Suite
$1,431
From
US$814
Save 705
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ships: Crown Princess, Emerald Princess (+3 more), Grand Princess, Island Princess, Sapphire Princess
Departures: Feb 2026 to Apr 2028
Visit: USA, Aruba, Panama, Costa Rica, Mexico
Black Friday Sale
Princess Standard
Inside
$1,249
Oceanview
$1,559
Balcony
$2,199
Suite
$3,274
From
US$1,249
Per Person
View Trip
13 Day Sapphire Sojourn with Regent Seven Seas
Cruise

13 Days (12 Nights) Los Angeles to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 10 February 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,958
Suite
$8,448
From
US$7,958
Save 14,240
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ships: Coral Princess, Island Princess
Departures: Jan 2026 to Apr 2027
Visit: USA, Mexico, Costa Rica, Panama, Aruba
Black Friday Sale
Princess Standard
Inside
$1,049
Oceanview
$1,049
Balcony
$2,079
Suite
$2,874
From
US$1,049
Per Person
View Trip
12 Day Panama Canal & Southern Caribbean with Celebrity Cruises
Cruise

12 Days (11 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 14 February 2028
Visit: USA, Aruba, Curacao, Panama, Cayman Islands
Exclusive Savings
Inside
$2,162
Oceanview
$2,362
Balcony
$2,712
Suite
$7,177
From
US$2,162
Save 1,070
Per Person
View Trip
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