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Cruises from Miami to Panama City

Are you looking for a cruise from Miami to Panama City? January is the most popular month to cruise between Miami and Panama City and there are 8 departures available from four of the world's leading cruise lines.
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15 Days
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$2,900pp
$32,598pp
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7 Cruises (8 Cruise Departures)
11 Day Caribbean & Panama Canal Passage with Seabourn
Cruise

11 Days (10 Nights) Miami to Panama City
Cruise Line: Seabourn
Ship: Seabourn Encore
Departure: 02 December 2025
Countries Visited: USA, Bonaire, Curacao, Colombia (+1 more), Panama
Exclusive DealBonus Onboard Credit
INSIDE
-
OCEANVIEW
-
BALCONY
$6,709
SUITE
$10,899
From (per person) 6,709
View Trip
11 Day Vivid Western Caribbean with Oceania Cruises
Cruise

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 14 April 2026
Countries Visited: USA, Mexico, Belize, Honduras (+2 more), Costa Rica, Panama
Fleetwide SaleExclusive Deal
INSIDE
$2,970
OCEANVIEW
$3,240
BALCONY
$4,680
SUITE
$6,480
Save (per person) 3,628
From (per person) 2,970
View Trip
11 Day Passage To Panama with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 17 January 2026
Countries Visited: USA, Mexico, Belize, Guatemala (+3 more), Honduras, Costa Rica, Panama
Fleetwide SaleExclusive Deal
INSIDE
$2,970
OCEANVIEW
$3,240
BALCONY
$4,680
SUITE
$6,570
Save (per person) 3,628
From (per person) 2,970
View Trip
11 Day A Journey Through Enchanting Nature & The Marvels Of The Panama Canal with Explora Journeys
Cruise

11 Days (10 Nights) Miami to Panama City
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 12 April 2027
Countries Visited: USA, Jamaica, Curacao, Aruba (+2 more), Colombia, Panama
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$6,160
SUITE
$7,160
From (per person) 6,160
View Trip
15 Day Exotic Coasts & Casco Viejo with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 23 February 2027
Countries Visited: USA, Mexico, Belize, Honduras (+5 more), Cayman Islands, Jamaica, Costa Rica, Colombia, Panama
Early Booking Saving
INSIDE
-
OCEANVIEW
-
BALCONY
$9,199
SUITE
$9,849
Save (per person) 15,399
From (per person) 9,199
View Trip
11 Day Panama Potpourri with Oceania Cruises
Cruise

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departures: Jan 2027 to Mar 2027
Countries Visited: USA, Mexico, Belize, Guatemala (+3 more), Honduras, Costa Rica, Panama
Exclusive Deal
INSIDE
$3,199
OCEANVIEW
$3,999
BALCONY
$4,699
SUITE
$6,899
Save (per person) 3,199
From (per person) 3,199
View Trip
15 Day Tropical Treasures with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 12 January 2027
Countries Visited: USA, Mexico, Belize, Honduras (+5 more), Cayman Islands, Jamaica, Costa Rica, Colombia, Panama
Early Booking Saving
INSIDE
-
OCEANVIEW
-
BALCONY
$13,099
SUITE
$13,849
Save (per person) 19,499
From (per person) 13,099
View Trip
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Cruises from Miami to Panama City Cruises from Miami to San Juan

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Cruises from USA to Panama

Cruise Lines Exploring The Caribbean & Bahamas

Azamara Caribbean Cruises Celebrity Caribbean Cruises Cunard Caribbean Cruises Emerald Caribbean Cruises Holland America Caribbean Cruises MSC Caribbean Cruises NCL Caribbean Cruises Oceania Caribbean Cruises Ponant Caribbean Cruises Princess Caribbean Cruises Regent Seven Seas Caribbean Cruises Royal Caribbean Caribbean Cruises Scenic Caribbean Cruises Seabourn Caribbean Cruises Silversea Caribbean Cruises Viking Caribbean Cruises Virgin Voyages Caribbean Cruises

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