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Panama Cruises Starting In October 2026, 2027 and 2028

If you're looking at joining a cruise to Panama in October 2026, 2027 or 2028, we have 16 unique cruise itineraries and 63 departures available, operated by eight of the world's leading cruise lines departing in October.
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16 Cruises (63 Departures)
16 Cruises (63 Departures)
Departures
Duration
8 Days
24 Days
Countries Visited
Start & End Cities
Ship Size
Ship Features
Operators
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Price
$1,300pp
$47,840pp
Countries
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11 Day From Panama’s Wild Beauty to Peruvian Shores with Ponant
Cruise
 (1)

11 Days (10 Nights) Colon to Lima
Operator: Ponant
Ship: L'Austral
Departure: 20 October 2026
Visits: Panama, Peru
Exclusive Savings
Oceanview
$8,452
Balcony
$9,101
Suite
$16,939
From (Per Person)
A$8,452
Save 218
Per Person
View Trip
10 Day Panama and Costa Rica: Crossing the Canal with Aurora Expeditions
New ReleaseCruise

10 Days (9 Nights) Panama City to San Jose
Operator: Aurora Expeditions
Ship: Douglas Mawson
Departure: 04 October 2027
Visits: Panama, Costa Rica
Exclusive Savings
Oceanview
$16,724
Balcony
$17,717
Suite
-
From (Per Person)
A$17,717
Per Person
View Trip
11 Day Pristine islands of the Bahamas & the Panama Canal with Scenic
New ReleaseCruise

11 Days (10 Nights) Nassau to Panama City
Operator: Scenic
Ship: Scenic Eclipse I
Departure: 16 October 2026
Visits: Bahamas, Colombia, Panama
Exclusive Savings
Balcony
$12,497
Suite
$12,742
From (Per Person)
A$12,497
Save 3,698
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Oct 2026 to Apr 2028
Visits: Panama, Colombia, Aruba, Curacao
Exclusive Savings
Inside
$1,416
Oceanview
$1,430
Balcony
$2,091
Suite
$2,487
From (Per Person)
A$1,416
Save 1,836
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Operator: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Oct 2026 to Mar 2028
Visits: Colombia, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,486
Oceanview
$1,621
Balcony
$2,195
Suite
$2,603
From (Per Person)
A$1,486
Save 1,461
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Operator: Princess
Ship: Star Princess
Departure: 04 October 2026
Visits: USA, Mexico, Panama, Aruba
Sanctuary Collection
Exclusive Savings
Inside
$2,363
Oceanview
$3,333
Balcony
$3,610
Suite
$6,105
From (Per Person)
A$2,363
Per Person
View Trip
12 Day Voyage of the Tropics: Bahamas, Caribbean & Panama Canal with Scenic
New ReleaseCruise

12 Days (11 Nights) Miami to Panama City
Operator: Scenic
Ship: Scenic Eclipse I
Departure: 13 October 2028
Visits: USA, Bahamas, Colombia, Panama
Exclusive Savings
Balcony
$14,042
Suite
$24,484
From (Per Person)
A$14,042
Save 2,703
Per Person
View Trip
17 Day Panama Canal - Ocean To Ocean with Princess
Cruise

17 Days (16 Nights) Los Angeles to Orlando
Operator: Princess
Ship: Star Princess
Departure: 10 October 2027
Visits: USA, Mexico, Panama, Aruba
Sanctuary Collection
Exclusive Savings
Inside
$2,828
Oceanview
$3,115
Balcony
$3,392
Suite
$5,333
From (Per Person)
A$2,828
Per Person
View Trip
22 Day America's Historic Journey to Panama with Scenic
New ReleaseCruise

22 Days (21 Nights) New York to Panama City
Operator: Scenic
Ship: Scenic Eclipse I
Departure: 05 October 2026
Visits: USA, Bahamas, Colombia, Panama
Exclusive Savings
Balcony
-
Suite
$38,196
From (Per Person)
A$38,196
Save 9,644
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

15 Days (14 Nights) San Diego to Miami
Operator: MSC Cruises
Ship: MSC Poesia
Departure: 03 October 2026
Visits: USA, Mexico, Costa Rica, Panama, Colombia
Exclusive Savings
Inside
$2,013
Oceanview
$2,152
Balcony
$2,845
Suite
-
From (Per Person)
A$2,013
Per Person
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

16 Days (15 Nights) Los Angeles to Miami
Operator: MSC Cruises
Ship: MSC Poesia
Departure: 02 October 2026
Visits: USA, Mexico, Costa Rica, Panama, Colombia
Exclusive Savings
Inside
$2,156
Oceanview
$2,314
Balcony
$3,047
Suite
-
From (Per Person)
A$2,156
Per Person
View Trip
24 Day Panama Canal & Pacific COast with Princess
Cruise

24 Days (23 Nights) Vancouver to Orlando
Operator: Princess
Ship: Star Princess
Departure: 03 October 2027
Visits: Canada, USA, Mexico, Panama, Aruba
Sanctuary Collection
Exclusive Savings
Inside
$4,069
Oceanview
-
Balcony
-
Suite
$7,495
From (Per Person)
A$4,069
Per Person
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise

11 Days (10 Nights) Fort Lauderdale to Panama City
Operator: Viking
Ship: Viking Mars
Departures: Nov 2027 to Dec 2028
Visits: USA, Mexico, Belize, Costa Rica, Panama
Exclusive Savings
Balcony
$8,129
Suite
$11,461
From (Per Person)
A$8,129
Save 180
Per Person
View Trip
14 Day Ancient Kingdoms and Natural Treasures: Panama to Chile with Scenic
New ReleaseCruise

14 Days (13 Nights) Panama City to Santiago
Operator: Scenic
Ships: Scenic Eclipse I
Departures: Oct 2027 to Oct 2028
Visits: Panama, Colombia, Ecuador, Peru, Chile
Exclusive Savings
Balcony
$13,769
Suite
$18,649
From (Per Person)
A$13,769
Save 6,226
Per Person
View Trip
21 Day Ultimate Voyage: Caribbean Islands & the Panama Canal with Scenic
New ReleaseCruise

21 Days (20 Nights) Nassau to Panama City
Operator: Scenic
Ship: Scenic Eclipse I
Departure: 04 October 2028
Visits: Bahamas, Turks and Caicos Islands, USA, Colombia, Panama
Exclusive Savings
Balcony
$23,529
Suite
$36,558
From (Per Person)
A$23,529
Save 5,361
Per Person
View Trip
17 Day Panama Canal & Historic Coasts Of South America with Seabourn
Cruise

17 Days (16 Nights) Oranjestad to Valparaiso
Operator: Seabourn
Ship: Seabourn Pursuit
Departure: 02 October 2028
Visits: Aruba, Panama, Ecuador, Peru, Chile
Exclusive Savings
Balcony
$13,967
Suite
$18,995
From (Per Person)
A$13,967
Save 252
Per Person
View Trip
Results: 16 results

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