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Panama Cruises Starting In October 2026, 2027 and 2028

If you're looking at joining a cruise to Panama in October 2026, 2027 or 2028, we have 14 unique cruise itineraries and 76 departures available, operated by six of the world's leading cruise lines departing in October.
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14 Cruises (76 Departures)
14 Cruises (76 Departures)
Departures
Duration
8 Days
24 Days
Countries Visited
Start & End Cities
Ship Size
Ship Features
Operators
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Price
$1,100pp
$39,155pp
Countries
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11 Day From Panama’s Wild Beauty to Peruvian Shores with Ponant
Cruise

11 Days (10 Nights) Colon to Lima
Cruise Line: Ponant
Ship: L'Austral
Departure: 20 October 2026
Visits: Panama, Peru
Exclusive Savings
Inside
-
Oceanview
$7,802
Balcony
$8,451
Suite
$16,289
From (Per Person)
A$7,802
Save 218
Per Person
View Trip
10 Day Panama and Costa Rica: Crossing the Canal with Aurora Expeditions
New ReleaseCruise

10 Days (9 Nights) Panama City to San Jose
Cruise Line: Aurora Expeditions
Ship: Douglas Mawson
Departure: 20 October 2027
Visits: Panama, Costa Rica
Exclusive Savings
Inside
-
Oceanview
$17,815
Balcony
$18,805
Suite
$28,309
From (Per Person)
A$17,815
Per Person
View Trip
10 Day Wellness Retreat - Panama City to Valparaiso with Scenic
New ReleaseCruise

10 Days (9 Nights) Panama City to Santiago
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 26 October 2026
Visits: Panama, Chile
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,290
Suite
$10,701
From (Per Person)
A$8,290
Save 3,105
Per Person
View Trip
11 Day Pristine islands of the Bahamas & the Panama Canal with Scenic
New ReleaseCruise

11 Days (10 Nights) Nassau to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 16 October 2026
Visits: Bahamas, Colombia, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,526
Suite
$14,702
From (Per Person)
A$13,526
Save 2,219
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Aug 2026 to Mar 2028
Visits: Colombia, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,460
Oceanview
$1,508
Balcony
$1,821
Suite
$2,230
From (Per Person)
A$1,460
Save 2,067
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Aug 2026 to Apr 2028
Visits: Panama, Colombia, Aruba, Curacao
Exclusive Savings
Inside
$1,191
Oceanview
$1,254
Balcony
$1,640
Suite
$2,161
From (Per Person)
A$1,191
Save 1,644
Per Person
View Trip
17 Day Panama Canal - Ocean To Ocean with Princess
Cruise

17 Days (16 Nights) Los Angeles to Orlando
Cruise Line: Princess
Ship: Star Princess
Departure: 10 October 2027
Visits: USA, Mexico, Panama, Aruba
Sanctuary Collection
Exclusive Savings
Inside
$2,783
Oceanview
$3,199
Balcony
$3,754
Suite
$5,555
From (Per Person)
A$2,783
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Star Princess
Departure: 04 October 2026
Visits: USA, Mexico, Panama, Aruba
Sanctuary Collection
Exclusive Savings
Inside
$2,229
Oceanview
$3,421
Balcony
$3,615
Suite
$5,417
From (Per Person)
A$2,229
Per Person
View Trip
12 Day Voyage of the Tropics: Bahamas, Caribbean & Panama Canal with Scenic
New ReleaseCruise

12 Days (11 Nights) Miami to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 13 October 2028
Visits: USA, Bahamas, Colombia, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,042
Suite
$24,484
From (Per Person)
A$14,042
Save 2,703
Per Person
View Trip
22 Day America's Historic Journey to Panama with Scenic
New ReleaseCruise

22 Days (21 Nights) New York to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 October 2026
Visits: USA, Bahamas, Colombia, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$33,115
Suite
$73,388
From (Per Person)
A$33,115
Save 6,040
Per Person
View Trip
21 Day Ultimate Voyage: Caribbean Islands & the Panama Canal with Scenic
New ReleaseCruise

21 Days (20 Nights) Nassau to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 04 October 2028
Visits: Bahamas, Turks and Caicos Islands, USA, Colombia, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$23,529
Suite
$36,558
From (Per Person)
A$23,529
Save 5,361
Per Person
View Trip
17 Day Panama Canal & Historic Coasts Of South America with Seabourn
Cruise

17 Days (16 Nights) Oranjestad to Valparaiso
Cruise Line: Seabourn
Ship: Seabourn Pursuit
Departure: 02 October 2028
Visits: Aruba, Panama, Ecuador, Peru, Chile
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,300
Suite
$22,180
From (Per Person)
A$16,300
Save 299
Per Person
View Trip
14 Day Ancient Kingdoms and Natural Treasures: Panama to Chile with Scenic
New ReleaseCruise

14 Days (13 Nights) Panama City to Santiago
Cruise Line: Scenic
Ships: Scenic Eclipse I
Departures: Oct 2027 to Oct 2028
Visits: Panama, Colombia, Ecuador, Peru, Chile
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,406
Suite
$18,649
From (Per Person)
A$14,406
Save 6,239
Per Person
View Trip
24 Day Panama Canal & Pacific COast with Princess
Cruise

24 Days (23 Nights) Vancouver to Orlando
Cruise Line: Princess
Ship: Star Princess
Departure: 03 October 2027
Visits: Canada, USA, Mexico, Panama, Aruba
Sanctuary Collection
Exclusive Savings
Inside
$4,274
Oceanview
$5,293
Balcony
$5,838
Suite
$7,917
From (Per Person)
A$4,274
Per Person
View Trip
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