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Panama Cruises Starting In January 2027 and 2028

If you're looking at joining a cruise to Panama in January 2027 or 2028, we have 26 unique cruise itineraries and 148 departures available, operated by ten of the world's leading cruise lines departing in January.
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26 Cruises (148 Cruise Departures)
8 Day Coastal Adventures: Panama & Costa Rica with Emerald Cruises
Cruise
 (3)

8 Days (7 Nights) Panama City to San Jose
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 24 January 2028
Visit: Panama, Costa Rica
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$6,051
Balcony
-
Suite
$7,748
From
US$6,051
Save 8,439
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (2)

8 Days (7 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 15 January 2027
Visit: Panama, Costa Rica
Inside
-
Oceanview
-
Balcony
$5,980
Suite
$10,150
From
US$5,980
Per Person
View Trip
12 Day The Panama Canal & Costa Rica - Eastbound with Tauck
Tour + Cruise

12 Days Puntarenas to Panama City or San Jose to Panama City
Operated By: Tauck
Ships: Le Lapérouse, Le Champlain
Departures: Feb 2026 to Feb 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Costa Rica, Panama
From
US$9,290
Per Person
View Trip
12 Day The Panama Canal & Costa Rica - Westbound with Tauck
Tour + Cruise

12 Days Panama City to San Jose
Operated By: Tauck
Ships: Le Lapérouse, Le Champlain
Departures: Feb 2026 to Feb 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Panama, Costa Rica
From
US$9,290
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2028 to Apr 2028
Visit: Panama, Colombia, Curacao, Aruba
Bonus Onboard Credit
Exclusive Savings
Inside
$839
Oceanview
$949
Balcony
$1,329
Suite
$1,348
From
US$839
Save 542
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2028 to Apr 2028
Visit: Colombia, Curacao, Aruba, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$866
Oceanview
$997
Balcony
$1,406
Suite
$1,436
From
US$866
Save 572
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ships: Grandeur of the Seas, Serenade of the Seas
Departures: Mar 2026 to Apr 2028
Visit: Colombia, Curacao, Aruba, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$838
Oceanview
$958
Balcony
$1,260
Suite
$1,408
From
US$838
Save 645
Per Person
View Trip
11 Day Panama, Ecuadaor & Peru Cruise: Panama City, Manta & Lima (Callao) with Azamara Cruises
Cruise
 (4)

11 Days (10 Nights) Panama City to Valparaiso
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 14 January 2028
Visit: Panama, Ecuador, Peru, Chile
Azamara Always Included
Exclusive Savings
Inside
$3,165
Oceanview
$3,708
Balcony
$4,552
Suite
$6,657
From
US$3,165
Save 74
Per Person
View Trip
13 Day World Cruise: Panama Canal To Callao with Seabourn
Cruise
 (1)

13 Days (12 Nights) Miami to Lima
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 January 2027
Visit: USA, Panama, Ecuador, Peru
Explore More
Exclusive Savings
Inside
-
Oceanview
$5,284
Balcony
$6,778
Suite
-
From
US$5,284
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ships: Grandeur of the Seas, Serenade of the Seas
Departures: Feb 2026 to Jan 2028
Visit: Colombia, Aruba, Curacao, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$898
Oceanview
$1,028
Balcony
$1,140
Suite
$1,488
From
US$898
Save 709
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ships: Grandeur of the Seas, Serenade of the Seas
Departures: Mar 2026 to Apr 2028
Visit: Panama, Colombia, Curacao, Aruba
Bonus Onboard Credit
Exclusive Savings
Inside
$797
Oceanview
$907
Balcony
$1,253
Suite
$1,316
From
US$797
Save 593
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: May 2026 to Mar 2028
Visit: Colombia, Aruba, Curacao, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$781
Oceanview
$827
Balcony
$1,177
Suite
$1,221
From
US$781
Save 763
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: May 2026 to Apr 2028
Visit: Panama, Colombia, Aruba, Curacao
Bonus Onboard Credit
Exclusive Savings
Inside
$671
Oceanview
$688
Balcony
$1,029
Suite
$1,102
From
US$671
Save 649
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ships: Grandeur of the Seas, Serenade of the Seas
Departures: Feb 2026 to Jan 2028
Visit: Panama, Colombia, Aruba, Curacao
Bonus Onboard Credit
Exclusive Savings
Inside
$861
Oceanview
$981
Balcony
$1,213
Suite
$1,390
From
US$861
Save 610
Per Person
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise
 (8)

11 Days (10 Nights) Panama City to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Nov 2027 to Jan 2028
Visit: Panama, Costa Rica, Belize, Mexico, USA
Viking $999 Air Deal
Inside
-
Oceanview
-
Balcony
$3,799
Suite
$6,499
From
US$3,799
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departure: 29 January 2027
Visit: USA, Mexico, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,749
Oceanview
$1,829
Balcony
$2,999
Suite
$3,793
From
US$1,749
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 30 January 2027
Visit: Panama, Colombia, Curacao, Aruba, Bonaire
Bonus Onboard Credit
Exclusive Savings
Inside
$809
Oceanview
$919
Balcony
$1,308
Suite
$1,328
From
US$809
Save 458
Per Person
View Trip
16 Day Miami To Los Angeles with Cunard
Cruise

16 Days (15 Nights) Miami to Los Angeles
Cruise Line: Cunard
Ship: Queen Anne
Departure: 23 January 2028
Visit: USA, Colombia, Panama, Guatemala, Mexico
Inside
$3,729
Oceanview
$4,579
Balcony
$5,579
Suite
$10,434
From
US$3,729
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ships: Crown Princess, Emerald Princess (+3 more), Grand Princess, Island Princess, Sapphire Princess
Departures: Apr 2026 to Apr 2028
Visit: USA, Aruba, Panama, Costa Rica, Mexico
Princess Standard
Exclusive Savings
Inside
$1,449
Oceanview
$1,569
Balcony
$2,119
Suite
$3,149
From
US$1,449
Save 51
Per Person
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise
 (8)

11 Days (10 Nights) Fort Lauderdale to Panama City
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Nov 2027 to Jan 2028
Visit: USA, Mexico, Belize, Costa Rica, Panama
Viking $999 Air Deal
Inside
-
Oceanview
-
Balcony
$3,799
Suite
$6,499
From
US$3,799
Per Person
View Trip
18 Day New York To Los Angeles with Cunard
Cruise
 (1)

18 Days (17 Nights) New York to Los Angeles
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 19 January 2027
Visit: USA, Aruba, Panama, El Salvador, Mexico
Inside
$3,529
Oceanview
$3,569
Balcony
$3,789
Suite
-
From
US$3,529
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to San Diego
Cruise Line: Princess
Ship: Island Princess
Departure: 13 January 2027
Visit: USA, Aruba, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,749
Oceanview
$1,779
Balcony
$2,979
Suite
$3,694
From
US$1,749
Per Person
View Trip
24 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

24 Days (23 Nights) Fort Lauderdale to Honolulu
Cruise Line: Princess
Ship: Coral Princess
Departure: 06 January 2027
Visit: USA, Colombia, Panama, Costa Rica, Mexico
Princess Standard
Inside
$3,121
Oceanview
$3,359
Balcony
$4,528
Suite
$7,174
From
US$3,121
Per Person
View Trip
16 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (4)

16 Days (15 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Coral Princess
Departure: 06 January 2027
Visit: USA, Colombia, Panama, Costa Rica, Mexico
Princess Standard
Inside
$2,102
Oceanview
$2,328
Balcony
$3,052
Suite
$3,337
From
US$2,102
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 31 January 2027
Visit: Colombia, Curacao, Aruba, Bonaire, Panama
Bonus Onboard Credit
Exclusive Savings
Inside
$942
Oceanview
$970
Balcony
$1,390
Suite
$1,420
From
US$942
Save 524
Per Person
View Trip
15 Day Cartagena to Valparaiso with Silversea
Cruise

15 Days (14 Nights) Cartagena to Valparaiso
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 15 January 2028
Visit: Colombia, Panama, Ecuador, Peru, Chile
All-Inclusive Fare
Inside
-
Oceanview
$8,000
Balcony
$9,600
Suite
-
From
US$8,000
Per Person
View Trip
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