Home > Cruises > Central America Cruises > Panama > December

Panama Cruises Starting In December 2026, 2027 and 2028

If you're looking at joining a cruise to Panama in December 2026, 2027 or 2028, we have 16 unique cruise itineraries and 102 departures available, operated by six of the world's leading cruise lines departing in December.
Filter Results
16 Cruises (102 Departures)
16 Cruises (102 Departures)
Departures
Duration
8 Days
18 Days
Countries Visited
Start & End Cities
Ship Size
Ship Features
Operators
Show More...
Price
$1,200pp
$88,740pp
Countries
Show More...
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Puntarenas to Colon
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Dec 2026 to Apr 2028
Visits: Costa Rica, Panama
Exclusive Savings
Balcony
$10,440
Suite
$17,366
From (Per Person)
A$10,440
Save 460
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Nov 2026 to Dec 2027
Visits: Panama, Costa Rica
Exclusive Savings
Balcony
$10,440
Suite
$17,366
From (Per Person)
A$10,440
Save 1,140
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (1)

8 Days (7 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Nov 2026 to Dec 2027
Visits: Panama, Costa Rica
Exclusive Savings
Balcony
$7,304
Suite
$12,154
From (Per Person)
A$7,304
Save 258
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Aug 2026 to Mar 2028
Visits: Colombia, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,633
Oceanview
$1,789
Balcony
$2,217
Suite
$4,082
From (Per Person)
A$1,633
Save 1,352
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Apr 2028
Visits: Colombia, Curacao, Aruba, Panama
Exclusive Savings
Inside
$1,635
Oceanview
$1,791
Balcony
$2,445
Suite
$4,148
From (Per Person)
A$1,635
Save 922
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Apr 2028
Visits: Panama, Colombia, Curacao, Aruba
Exclusive Savings
Inside
$1,559
Oceanview
$1,716
Balcony
$2,328
Suite
$3,903
From (Per Person)
A$1,559
Save 1,008
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Aug 2026 to Apr 2028
Visits: Panama, Colombia, Aruba, Curacao
Exclusive Savings
Inside
$1,262
Oceanview
$1,303
Balcony
$1,898
Suite
$3,652
From (Per Person)
A$1,262
Save 1,152
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Island Princess
Departure: 13 December 2027
Visits: USA, Aruba, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$2,091
Oceanview
$2,368
Balcony
$3,352
Suite
$5,556
From (Per Person)
A$2,091
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departure: 28 December 2026
Visits: USA, Mexico, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$2,833
Oceanview
$3,463
Balcony
$3,574
Suite
$5,556
From (Per Person)
A$2,833
Per Person
View Trip
16 Day Panama Canal Holiday with Holland America
Cruise
 (5)

16 Days (15 Nights) San Diego to Miami
Cruise Line: Holland America
Ship: Zaandam
Departure: 18 December 2027
Visits: USA, Mexico, Costa Rica, Panama, Colombia
Fare Saver
Exclusive Savings
Inside
$4,153
Oceanview
$4,608
Balcony
$7,677
Suite
$14,736
From (Per Person)
A$4,153
Per Person
View Trip
11 Day A Journey Through Caribbean Havens & the Tropical Gems of Seaside Cities with Explora Journeys
Cruise
 (1)

11 Days (10 Nights) Miami to Miami
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 02 December 2027
Visits: USA, Jamaica, Panama, Costa Rica, Colombia
Exclusive Savings
Suite
$8,060
From (Per Person)
A$8,060
Save 165
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (12)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Crown Princess
Departure: 03 December 2026
Visits: USA, Mexico, Costa Rica, Panama, Curacao
Exclusive Savings
Inside
$1,766
Oceanview
$1,760
Balcony
$3,201
Suite
$5,201
From (Per Person)
A$1,760
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Island Princess
Departure: 12 December 2026
Visits: USA, Aruba, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$2,052
Oceanview
$2,050
Balcony
$2,923
Suite
$4,230
From (Per Person)
A$2,050
Per Person
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise

11 Days (10 Nights) Fort Lauderdale to Panama City
Cruise Line: Viking
Ship: Viking Mars
Departures: Nov 2027 to Dec 2028
Visits: USA, Mexico, Belize, Costa Rica, Panama
Exclusive Savings
Balcony
$5,434
Suite
$8,815
From (Per Person)
A$5,434
Save 1,377
Per Person
View Trip
18 Day Panama Canal & the Pacific Coast with Viking Cruises
Cruise

18 Days (17 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Viking
Ships: Viking Sky, Viking Vesta
Departures: Dec 2026 to Dec 2028
Visits: USA, Mexico, Colombia, Panama, Costa Rica
Exclusive Savings
Balcony
$9,354
Suite
$17,684
From (Per Person)
A$9,354
Save 1,447
Per Person
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise

11 Days (10 Nights) Panama City to Fort Lauderdale
Cruise Line: Viking
Ship: Viking Mars
Departures: Nov 2027 to Dec 2028
Visits: Panama, Costa Rica, Belize, Mexico, USA
Exclusive Savings
Balcony
$5,434
Suite
$8,815
From (Per Person)
A$5,434
Save 1,387
Per Person
View Trip
Results: 16 results

No trips found. Try adjusting the search filters.




Cruises found! Scroll up to view.

South & Central America Cruises

Central America Cruises South America Cruises Mexico Cruises Galapagos Cruises Bermunda Cruises Bahamas Cruises Caribbean Cruises Amazon Cruises Patagonia Cruises Cape Horn Cruises Falkland Island Cruises Panama Cruises

Travel Styles

Luxury Cruises

Trip Lengths

10 Day 2 Week 3 Week 7 Day

Departure Months

August September October November December January February March April

Cities

Colon Panama City Santiago

Routes

Colon to Colon Miami to Panama City Panama City to Miami

Country Routes

Panama to USA USA to Panama

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

Central America Tours

All Central America Tours Belize Tours Costa Rica Tours Guatemala Tours Mexico Tours Panama Tours

© 2010-2026. Global Journeys. You're viewing our site in Australian dollars.

    

Global Journeys | Terms & Conditions

Global Journeys Pty Ltd. Accredited Member of The Australian Travel Industry Association (ATIA). No. A11351.

Travel Industry Associations