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Panama Cruises Starting In December 2026 and 2027

If you're looking at joining a cruise to Panama in December 2026 or 2027, we have 16 unique cruise itineraries and 99 departures available, operated by six of the world's leading cruise lines departing in December.
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16 Cruises (99 Departures)
16 Cruises (99 Departures)
Departures
Duration
8 Days
18 Days
Countries Visited
Start & End Cities
Ship Size
Ship Features
Operators
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Price
$1,000pp
$88,740pp
Countries
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11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Nov 2026 to Dec 2027
Visits: Panama, Costa Rica
Exclusive Savings
Balcony
$9,790
Suite
$16,716
From (Per Person)
A$9,790
Save 1,140
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (1)

8 Days (7 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Nov 2026 to Dec 2027
Visits: Panama, Costa Rica
Exclusive Savings
Balcony
$6,854
Suite
$11,704
From (Per Person)
A$6,854
Save 258
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Puntarenas to Colon
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Dec 2026 to Apr 2028
Visits: Costa Rica, Panama
Exclusive Savings
Balcony
$9,790
Suite
$16,716
From (Per Person)
A$9,790
Save 435
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Apr 2028
Visits: Panama, Colombia, Curacao, Aruba
Exclusive Savings
Inside
$1,386
Oceanview
$1,543
Balcony
$2,032
Suite
$2,251
From (Per Person)
A$1,628
Save 935
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Aug 2026 to Mar 2028
Visits: Colombia, Aruba, Curacao, Panama
Exclusive Savings
Inside
$1,460
Oceanview
$1,516
Balcony
$1,839
Suite
$1,907
From (Per Person)
A$1,614
Save 1,939
Per Person
View Trip
8 Day Southern Caribbean Holiday with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 20 December 2026
Visits: Colombia, Aruba, Bonaire, Panama
Exclusive Savings
Inside
$1,870
Oceanview
$1,877
Balcony
$2,476
Suite
$2,897
From (Per Person)
A$2,189
Save 913
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Aug 2026 to Apr 2028
Visits: Panama, Colombia, Aruba, Curacao
Exclusive Savings
Inside
$1,032
Oceanview
$1,068
Balcony
$1,467
Suite
$1,835
From (Per Person)
A$1,032
Save 1,210
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Cartagena to Cartagena
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departures: Jan 2027 to Apr 2028
Visits: Colombia, Curacao, Aruba, Panama
Exclusive Savings
Inside
$1,462
Oceanview
$1,618
Balcony
$2,197
Suite
$2,410
From (Per Person)
A$1,726
Save 661
Per Person
View Trip
8 Day Southern Caribbean Holiday Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) Colon to Colon
Cruise Line: Royal Caribbean
Ship: Grandeur of the Seas
Departure: 19 December 2026
Visits: Panama, Colombia, Aruba, Bonaire
Exclusive Savings
Inside
$1,442
Oceanview
$1,583
Balcony
$2,546
Suite
$2,557
From (Per Person)
A$1,701
Save 782
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departure: 28 December 2026
Visits: USA, Mexico, Costa Rica, Panama, Aruba
Exclusive Savings
Inside
$2,833
Oceanview
$3,311
Balcony
$3,380
Suite
$5,417
From (Per Person)
A$2,833
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Island Princess
Departure: 12 December 2026
Visits: USA, Aruba, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$2,161
Oceanview
$2,258
Balcony
$3,186
Suite
$3,745
From (Per Person)
A$2,161
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (12)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ship: Crown Princess
Departure: 03 December 2026
Visits: USA, Mexico, Costa Rica, Panama, Curacao
Exclusive Savings
Inside
$1,875
Oceanview
$1,968
Balcony
$2,983
Suite
$4,508
From (Per Person)
A$1,875
Per Person
View Trip
16 Day Panama Canal Holiday with Holland America
Cruise
 (5)

16 Days (15 Nights) San Diego to Miami
Cruise Line: Holland America
Ship: Zaandam
Departure: 18 December 2027
Visits: USA, Mexico, Costa Rica, Panama, Colombia
Fare Saver
Exclusive Savings
Inside
$4,153
Oceanview
$4,608
Balcony
$7,677
Suite
$14,736
From (Per Person)
A$4,153
Per Person
View Trip
11 Day A Journey Through Caribbean Havens & the Tropical Gems of Seaside Cities with Explora Journeys
Cruise
 (1)

11 Days (10 Nights) Miami to Miami
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 02 December 2027
Visits: USA, Jamaica, Panama, Costa Rica, Colombia
Exclusive Savings
Suite
$8,060
From (Per Person)
A$8,060
Save 165
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean Holiday with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Princess
Ship: Island Princess
Departure: 13 December 2027
Visits: USA, Aruba, Panama, Costa Rica, Mexico
Exclusive Savings
Inside
$2,091
Oceanview
$2,368
Balcony
$3,338
Suite
$5,556
From (Per Person)
A$2,091
Per Person
View Trip
18 Day Panama Canal & the Pacific Coast with Viking Cruises
Cruise

18 Days (17 Nights) Fort Lauderdale to Los Angeles
Cruise Line: Viking
Ships: Viking Sky, Viking Vesta
Departures: Dec 2026 to Dec 2027
Visits: USA, Mexico, Colombia, Panama, Costa Rica
Exclusive Savings
Balcony
$9,452
Suite
$17,684
From (Per Person)
A$9,452
Save 1,443
Per Person
View Trip
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