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Central America Luxury Cruises

Explore the best luxury cruises to Central America. Choose from 106 unique cruise itineraries from 10 leading cruise lines. January is the most popular month to join a luxury cruise to Central America with 113 departures starting between February 2026 and April 2028.
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181 Days
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106 Cruises (113 Cruise Departures)
8 Day Panama and Costa Rica by Sea: The Natural Wonders of Central America – with Smithsonian Journeys with Ponant
Cruise

8 Days (7 Nights) Puntarenas to Colon
Cruise Line: Ponant
Ships: Le Champlain, Le Laperouse
Departures: Feb 2026 to Feb 2027
Visit: Costa Rica, Panama
Inside
-
Oceanview
-
Balcony
$6,600
Suite
$11,050
From
US$6,600
Per Person
View Trip
17 Day Panama Canal Coastlines with Oceania Cruises
Cruise

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 06 January 2028
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,389
Suite
$11,493
From
US$8,389
Save 8,809
Per Person
View Trip
17 Day Holiday In Panama with Regent Seven Seas
Cruise

17 Days (16 Nights) Miami to San Francisco
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 20 December 2027
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,036
Suite
$10,771
From
US$10,036
Save 17,362
Per Person
View Trip
19 Day Panama Canal Cruise: Colombia, Costa Rica & Mexico with Azamara Cruises
Cruise
 (4)

19 Days (18 Nights) Miami to San Francisco
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 18 December 2026
Visit: USA, Dominican Republic, Colombia, Panama, Costa Rica, Guatemala, Mexico
Azamara Always Included
Exclusive Savings
Inside
$4,514
Oceanview
$5,193
Balcony
$5,659
Suite
$9,189
From
US$4,514
Save 85
Per Person
View Trip
21 Day Seattle to Miami with Silversea
Cruise
 (1)

21 Days (20 Nights) Seattle to Miami
Cruise Line: Silversea
Ship: Silver Nova
Departure: 11 May 2026
Visit: USA, Mexico, Costa Rica, Panama, Colombia
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$16,870
From
US$16,870
Save 3,030
Per Person
View Trip
11 Day Central American Seas with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 06 January 2028
Visit: USA, Mexico, Belize, Honduras, Costa Rica, Panama
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
$3,047
Oceanview
$4,017
Balcony
$4,793
Suite
$6,733
From
US$3,047
Save 3,151
Per Person
View Trip
11 Day Pristine islands of the Bahamas & the Panama Canal with Scenic
New ReleaseCruise

11 Days (10 Nights) Nassau to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 16 October 2026
Visit: Bahamas, Colombia, Panama
Wave Offer
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,244
Suite
$11,475
From
US$9,244
Save 13,746
Per Person
View Trip
8 Day Pacific Coast of Costa Rica with Ponant
Cruise
 (1)

8 Days (7 Nights) Puntarenas to Puntarenas
Cruise Line: Ponant
Ships: Le Bellot, Le Laperouse
Departures: Dec 2026 to Dec 2026
Visit: Costa Rica
Inside
-
Oceanview
-
Balcony
$6,550
Suite
$11,120
From
US$6,550
Per Person
View Trip
13 Day Costa Rica, Panama from the Pacific to the Atlantic via the Panama Canal with Emerald Cruises
New ReleaseCruise
 (3)

13 Days (12 Nights) San Jose to San Jose
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 10 February 2028
Visit: Costa Rica, Panama
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$10,230
Balcony
-
Suite
$12,898
From
US$10,230
Save 12,760
Per Person
View Trip
17 Day Halcyon Holidays with Oceania Cruises
Cruise

17 Days (16 Nights) Miami to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 19 December 2027
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,485
Suite
$11,589
From
US$8,485
Save 8,913
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (1)

8 Days (7 Nights) Puntarenas to Colon
Cruise Line: Ponant
Ships: Le Bellot, Le Laperouse
Departures: Nov 2026 to Mar 2027
Visit: Costa Rica, Panama
Inside
-
Oceanview
-
Balcony
$5,300
Suite
$8,950
From
US$5,300
Per Person
View Trip
16 Day Miami To Los Angeles with Cunard
Cruise

16 Days (15 Nights) Miami to Los Angeles
Cruise Line: Cunard
Ship: Queen Anne
Departure: 23 January 2028
Visit: USA, Colombia, Panama, Guatemala, Mexico
Inside
$3,729
Oceanview
$4,579
Balcony
$5,579
Suite
$10,434
From
US$3,729
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (1)

8 Days (7 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ships: Le Bellot, Le Laperouse
Departures: Nov 2026 to Feb 2027
Visit: Panama, Costa Rica
Inside
-
Oceanview
-
Balcony
$5,970
Suite
$10,140
From
US$5,970
Per Person
View Trip
13 Day World Cruise: Panama Canal To Callao with Seabourn
Cruise
 (1)

13 Days (12 Nights) Miami to Lima
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 January 2027
Visit: USA, Panama, Ecuador, Peru
Explore More
Exclusive Savings
Inside
-
Oceanview
$5,284
Balcony
$6,778
Suite
-
From
US$5,284
Per Person
View Trip
11 Day Spanish Lullaby with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 March 2028
Visit: Panama, Costa Rica, Honduras, Guatemala, Mexico, USA
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$2,946
Oceanview
$3,916
Balcony
$4,692
Suite
$6,729
From
US$2,946
Save 3,052
Per Person
View Trip
8 Day Coastal Adventures: Costa Rica & Panama with Emerald Cruises
Cruise
 (3)

8 Days (7 Nights) San Jose to Panama City
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 22 February 2028
Visit: Costa Rica, Panama
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$6,070
Balcony
-
Suite
$7,768
From
US$6,070
Save 8,420
Per Person
View Trip
8 Day Coastal Adventures: Panama & Costa Rica with Emerald Cruises
Cruise
 (3)

8 Days (7 Nights) Panama City to San Jose
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 24 January 2028
Visit: Panama, Costa Rica
Early Payment Discount
Exclusive Savings
Inside
-
Oceanview
$6,051
Balcony
-
Suite
$7,748
From
US$6,051
Save 8,439
Per Person
View Trip
15 Day Los Angeles To Miami with Cunard
Cruise
 (13)

15 Days (14 Nights) Los Angeles to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 13 April 2028
Visit: USA, Mexico, Costa Rica, Panama, Aruba
Inside
$3,129
Oceanview
$3,629
Balcony
$4,529
Suite
-
From
US$3,129
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (2)

8 Days (7 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 15 January 2027
Visit: Panama, Costa Rica
Inside
-
Oceanview
-
Balcony
$5,980
Suite
$10,150
From
US$5,980
Per Person
View Trip
19 Day Transamerican Treasures with Oceania Cruises
Cruise

19 Days (18 Nights) Miami to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 24 October 2027
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,746
Suite
$11,790
From
US$6,746
Save 7,052
Per Person
View Trip
19 Day Miami to Los Angeles with Silversea
Cruise

19 Days (18 Nights) Miami to Los Angeles
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 21 December 2026
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$8,240
Balcony
$10,240
Suite
$20,060
From
US$8,240
Save 2,060
Per Person
View Trip
8 Day Panama and Costa Rica by Sea: The Natural Wonders of Central America - with Smithsonian Journeys with Ponant
Cruise

8 Days (7 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ship: Le Champlain
Departure: 19 February 2026
Visit: Panama, Costa Rica
Inside
-
Oceanview
-
Balcony
$8,280
Suite
$16,170
From
US$8,280
Per Person
View Trip
19 Day An Extended Journey of Ancient Mysteries & Pacific Coastal Wonders with Explora Journeys
Cruise

19 Days (18 Nights) Panama City to Vancouver
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 22 April 2027
Visit: Panama, El Salvador, Guatemala, Mexico, USA, Canada
A Suite Invitation
Inside
-
Oceanview
-
Balcony
$10,795
Suite
$12,495
From
US$10,795
Per Person
View Trip
22 Day America's Historic Journey to Panama with Scenic
New ReleaseCruise

22 Days (21 Nights) New York to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 October 2026
Visit: USA, Bahamas, Colombia, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$47,076
Suite
$107,982
From
US$47,076
Save 1,314
Per Person
View Trip
18 Day Panama Canal & Latin America Cruise: Mexico, Costa Rica & Colombia with Azamara Cruises
Cruise
 (4)

18 Days (17 Nights) San Diego to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 May 2027
Visit: USA, Mexico, Guatemala, El Salvador, Costa Rica, Panama, Colombia
Azamara Always Included
Exclusive Savings
Inside
$5,994
Oceanview
$6,459
Balcony
$7,323
Suite
$12,017
From
US$5,994
Save 135
Per Person
View Trip
18 Day New York To Los Angeles with Cunard
Cruise
 (1)

18 Days (17 Nights) New York to Los Angeles
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 19 January 2027
Visit: USA, Aruba, Panama, El Salvador, Mexico
Inside
$3,529
Oceanview
$3,569
Balcony
$3,789
Suite
-
From
US$3,529
Per Person
View Trip
20 Day Panama Canal Passage with Seabourn
Cruise
 (1)

20 Days (19 Nights) Los Angeles to Miami
Cruise Line: Seabourn
Ship: Seabourn Quest
Departures: Apr 2026 to May 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Explore More
Exclusive Savings
Inside
-
Oceanview
$6,943
Balcony
$9,213
Suite
$18,793
From
US$6,943
Per Person
View Trip
13 Day Sapphire Sojourn with Regent Seven Seas
Cruise

13 Days (12 Nights) Los Angeles to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 10 February 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,595
Suite
$9,281
From
US$8,595
Save 14,903
Per Person
View Trip
21 Day Miami To Seattle with Cunard
Cruise
 (13)

21 Days (20 Nights) Miami to Seattle
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 14 April 2026
Visit: USA, Colombia, Panama, Costa Rica, Mexico
Inside
$1,499
Oceanview
$1,699
Balcony
$1,999
Suite
$5,699
From
US$1,499
Per Person
View Trip
36 Day Miami To Sydney with Cunard
Cruise

36 Days (35 Nights) Miami to Sydney
Cruise Line: Cunard
Ship: Queen Anne
Departure: 23 January 2028
Visit: USA, Colombia, Panama, Guatemala, Mexico, Fiji, Australia
Exclusive Savings
Inside
$6,749
Oceanview
$8,432
Balcony
$10,412
Suite
$20,411
From
US$6,749
Per Person
View Trip
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