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Central America Luxury Cruises

Explore the best luxury cruises to Central America. Choose from 97 unique cruise itineraries with 262 past traveler reviews from 10 leading cruise lines. January is the most popular month to join a luxury cruise to Central America with 123 departures starting between September 2026 and March 2029.
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177 Days
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97 Cruises (123 Cruise Departures)
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Nov 2026 to Dec 2027
Visit: Panama, Costa Rica
Inside
-
Oceanview
-
Balcony
$7,790
Suite
$13,140
From
US$7,790
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Puntarenas to Colon
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 23 February 2028
Visit: Costa Rica, Panama
Inside
-
Oceanview
-
Balcony
$8,290
Suite
$14,020
From
US$8,290
Per Person
View Trip
8 Day Pacific Coast of Costa Rica with Ponant
Cruise
 (1)

8 Days (7 Nights) Puntarenas to Puntarenas
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Dec 2026 to Jan 2028
Visit: Costa Rica
Inside
-
Oceanview
-
Balcony
$5,290
Suite
$8,940
From
US$5,290
Per Person
View Trip
8 Day Panama and Costa Rica by Sea: The Natural Wonders of Central America – with Smithsonian Journeys with Ponant
Cruise
 (2)

8 Days (7 Nights) Puntarenas to Colon
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 19 February 2027
Visit: Costa Rica, Panama
Inside
-
Oceanview
-
Balcony
$7,440
Suite
$12,530
From
US$7,440
Per Person
View Trip
15 Day Los Angeles To Miami with Cunard
Cruise
 (13)

15 Days (14 Nights) Los Angeles to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 13 April 2028
Visit: USA, Mexico, Costa Rica, Panama, Aruba
Value Fare
Inside
$3,119
Oceanview
$3,619
Balcony
$4,309
Suite
-
From
US$3,119
Per Person
View Trip
13 Day World Cruise: Panama Canal To Callao with Seabourn
Cruise
 (1)

13 Days (12 Nights) Miami to Lima
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 January 2027
Visit: USA, Panama, Ecuador, Peru
Inside
-
Oceanview
$6,298
Balcony
$7,598
Suite
$16,298
From
US$6,298
Per Person
View Trip
8 Day Coastal Adventures: Panama & Costa Rica with Emerald Cruises
Cruise
 (3)

8 Days (7 Nights) Panama City to San Jose
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 24 January 2028
Visit: Panama, Costa Rica
Inside
-
Oceanview
$7,095
Balcony
-
Suite
$8,845
From
US$7,095
Per Person
View Trip
11 Day Central American Seas with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 06 January 2028
Visit: USA, Mexico, Belize, Honduras, Costa Rica, Panama
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$3,099
Oceanview
$4,099
Balcony
$4,899
Suite
$7,049
From
US$3,099
Save 3,099
Per Person
View Trip
19 Day Panama Canal Cruise: Colombia, Costa Rica & Mexico with Azamara Cruises
Cruise
 (5)

19 Days (18 Nights) Miami to San Francisco
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 18 December 2026
Visit: USA, Dominican Republic, Colombia, Panama, Costa Rica, Guatemala, Mexico
Azamara Always Included
Inside
$4,229
Oceanview
$4,859
Balcony
$5,299
Suite
$8,219
From
US$4,229
Per Person
View Trip
15 Day Aruba, Colombia & Panama Cruise: Oranjestad, Cartagena & Panama City with Azamara Cruises
Cruise
 (8)

15 Days (14 Nights) Miami to Lima
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 05 January 2028
Visit: USA, Aruba, Curacao, Colombia, Panama, Ecuador, Peru
Azamara Always Included
Inside
$4,369
Oceanview
$4,869
Balcony
$5,639
Suite
$8,709
From
US$4,369
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (1)

8 Days (7 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Nov 2026 to Dec 2027
Visit: Panama, Costa Rica
Inside
-
Oceanview
-
Balcony
$5,450
Suite
$9,200
From
US$5,450
Per Person
View Trip
11 Day Secrets of Central America with Ponant
Cruise
 (1)

11 Days (10 Nights) Puntarenas to Colon
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Dec 2026 to Apr 2028
Visit: Costa Rica, Panama
Inside
-
Oceanview
-
Balcony
$7,790
Suite
$13,140
From
US$7,790
Per Person
View Trip
11 Day Spanish Lullaby with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 March 2028
Visit: Panama, Costa Rica, Honduras, Guatemala, Mexico, USA
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,999
Oceanview
$3,999
Balcony
$4,799
Suite
$6,899
From
US$2,999
Save 2,999
Per Person
View Trip
13 Day Costa Rica, Panama from the Pacific to the Atlantic via the Panama Canal with Emerald Cruises
New ReleaseCruise
 (3)

13 Days (12 Nights) San Jose to San Jose
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 10 February 2028
Visit: Costa Rica, Panama
Inside
-
Oceanview
$12,525
Balcony
-
Suite
$15,275
From
US$12,525
Per Person
View Trip
8 Day Coastal Adventures: Costa Rica & Panama with Emerald Cruises
Cruise
 (3)

8 Days (7 Nights) San Jose to Panama City
Cruise Line: Emerald Cruises
Ship: Emerald Azzurra
Departure: 22 February 2028
Visit: Costa Rica, Panama
Inside
-
Oceanview
$6,945
Balcony
-
Suite
$8,695
From
US$6,945
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (1)

8 Days (7 Nights) Puntarenas to Colon
Cruise Line: Ponant
Ships: Le Bellot, Le Bougainville, Le Laperouse
Departures: Nov 2026 to Jan 2028
Visit: Costa Rica, Panama
Inside
-
Oceanview
-
Balcony
$5,450
Suite
$9,200
From
US$5,450
Per Person
View Trip
8 Day Central America Jewels & Panama Canal with Ponant
Cruise
 (2)

8 Days (7 Nights) Colon to Puntarenas
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 15 January 2027
Visit: Panama, Costa Rica
Inside
-
Oceanview
-
Balcony
$6,990
Suite
$10,750
From
US$6,990
Per Person
View Trip
8 Day Ocean Voyage: Puntarenas - Cabo San Lucas with Ponant
Cruise
 (1)

8 Days (7 Nights) Puntarenas to Cabo San Lucas
Cruise Line: Ponant
Ship: Le Bellot
Departure: 18 January 2028
Visit: Costa Rica, Mexico
Inside
-
Oceanview
-
Balcony
$2,420
Suite
$3,530
From
US$2,420
Per Person
View Trip
16 Day Miami To Los Angeles with Cunard
Cruise

16 Days (15 Nights) Miami to Los Angeles
Cruise Line: Cunard
Ship: Queen Anne
Departure: 23 January 2028
Visit: USA, Colombia, Panama, Guatemala, Mexico
Value Fare
Inside
$3,419
Oceanview
$4,269
Balcony
$4,839
Suite
$9,099
From
US$3,419
Per Person
View Trip
17 Day Tropical Transit with Regent Seven Seas
Cruise

17 Days (16 Nights) Miami to Los Angeles
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 07 February 2029
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,399
Suite
$15,999
From
US$15,399
Save 15,399
Per Person
View Trip
11 Day Pristine islands of the Bahamas & the Panama Canal with Scenic
New ReleaseCruise

11 Days (10 Nights) Nassau to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 16 October 2026
Visit: Bahamas, Colombia, Panama
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,121
Suite
$12,011
From
US$10,121
Save 2,574
Per Person
View Trip
17 Day Halcyon Holidays with Oceania Cruises
Cruise

17 Days (16 Nights) Miami to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 19 December 2027
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,299
Suite
$11,899
From
US$8,299
Save 8,299
Per Person
View Trip
17 Day Panama Canal Coastlines with Oceania Cruises
Cruise

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 06 January 2028
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,599
Suite
$11,799
From
US$8,599
Save 8,599
Per Person
View Trip
19 Day Miami to Los Angeles with Silversea
Cruise

19 Days (18 Nights) Miami to Los Angeles
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 21 December 2026
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
$9,200
Balcony
$11,100
Suite
$20,500
From
US$9,200
Save 3,000
Per Person
View Trip
17 Day Pearls, Palapas & Panama with Regent Seven Seas
Cruise

17 Days (16 Nights) Los Angeles to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 05 March 2029
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,299
Suite
$15,899
From
US$15,299
Save 15,299
Per Person
View Trip
17 Day Holiday In Panama with Regent Seven Seas
Cruise

17 Days (16 Nights) Miami to San Francisco
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 20 December 2027
Visit: USA, Jamaica, Colombia, Panama, Costa Rica, Guatemala, Mexico
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$14,649
From
US$14,649
Save 14,649
Per Person
View Trip
19 Day Transamerican Treasures with Oceania Cruises
Cruise

19 Days (18 Nights) Miami to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 24 October 2027
Visit: USA, Cayman Islands, Colombia, Panama, Costa Rica, Guatemala, Mexico
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,099
Suite
$11,499
From
US$7,099
Save 7,099
Per Person
View Trip
22 Day America's Historic Journey to Panama with Scenic
New ReleaseCruise

22 Days (21 Nights) New York to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 October 2026
Visit: USA, Bahamas, Colombia, Panama
Inside
-
Oceanview
-
Balcony
-
Suite
$56,695
From
US$56,695
Per Person
View Trip
19 Day An Extended Journey of Ancient Mysteries & Pacific Coastal Wonders with Explora Journeys
Cruise

19 Days (18 Nights) Panama City to Vancouver
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 22 April 2027
Visit: Panama, El Salvador, Guatemala, Mexico, USA, Canada
Inside
-
Oceanview
-
Balcony
-
Suite
$11,840
From
US$11,840
Per Person
View Trip
20 Day Panama Canal Passage with Seabourn
Cruise
 (1)

20 Days (19 Nights) Los Angeles to Miami
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 11 May 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Inside
-
Oceanview
$8,998
Balcony
$12,898
Suite
$22,498
From
US$8,998
Per Person
View Trip
Results: 1-30 of 97

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