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Central America Luxury Cruises

Explore the best luxury cruises to Central America. Choose from 104 unique cruise itineraries with 264 past traveler reviews from 10 leading cruise lines. January is the most popular month to join a luxury cruise to Central America with 115 departures starting between April 2026 and April 2028.
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104 Cruises (115 Cruise Departures)
15 Day Tropical Treasures with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 12 January 2027
Visit: USA, Mexico, Belize, Honduras (+5 more), Cayman Islands, Jamaica, Costa Rica, Colombia, Panama
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,299
Suite
$17,999
From
US$17,299
Save 17,299
Per Person
View Trip
26 Day Ultimate Island Holiday with Regent Seven Seas
Cruise

26 Days (25 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 19 December 2027
Visit: USA, Virgin Islands, Saint Martin, Saint Barthelemy (+14 more), Saint Kitts and Nevis, Antigua and Barbuda, Dominica, Saint Lucia, Barbados, Grenada, Aruba, Bonaire, Curacao, Colombia, Panama, Costa Rica, Jamaica, Cayman Islands
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$20,349
Suite
$21,549
From
US$20,349
Save 20,349
Per Person
View Trip
15 Day Los Angeles To Miami with Cunard
Cruise

15 Days (14 Nights) Los Angeles to Miami
Cruise Line: Cunard
Ship: Queen Anne
Departure: 05 April 2026
Visit: USA, Guatemala, Panama, Curacao, Aruba
Inside
$1,689
Oceanview
-
Balcony
$2,909
Suite
$6,119
From
US$1,689
Per Person
View Trip
45 Day Sun, Sand & Seas Of Stars with Oceania Cruises
Cruise

45 Days (44 Nights) Los Angeles to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 06 January 2028
Visit: USA, Mexico, Guatemala, Costa Rica (+14 more), Panama, Colombia, Cayman Islands, Saint Martin, Martinique, Saint Lucia, Grenada, Aruba, Puerto Rico, Virgin Islands, Saint Kitts and Nevis, Guadeloupe, Honduras, Belize
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$21,899
Suite
$30,399
From
US$21,899
Save 21,899
Per Person
View Trip
22 Day An Extended Journey from Majestic Horizons to Mayan Gems with Explora Journeys
Cruise

22 Days (21 Nights) Miami to Los Angeles
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 12 April 2027
Visit: USA, Jamaica, Curacao, Aruba (+5 more), Colombia, Panama, El Salvador, Guatemala, Mexico
Inside
-
Oceanview
-
Balcony
-
Suite
$12,840
From
US$12,840
Per Person
View Trip
12 Day Panama Canal & the Alluring Islands of the Caribbean with Scenic
New ReleaseCruise

12 Days (11 Nights) Panama City to Bridgetown
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 13 April 2026
Visit: Panama, Colombia, Aruba, Curacao, Saint Vincent, Barbados
Inside
-
Oceanview
-
Balcony
$12,485
Suite
$29,150
From
US$12,485
Per Person
View Trip
15 Day A Festive Passage with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 22 December 2027
Visit: USA, Mexico, Guatemala, Belize (+5 more), Honduras, Costa Rica, Panama, Jamaica, Cayman Islands
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,399
Suite
$13,449
From
US$12,399
Save 12,399
Per Person
View Trip
12 Day Pristine Islands of the Caribbean & the Panama Canal with Scenic
New ReleaseCruise

12 Days (11 Nights) Bridgetown to Panama City
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 20 October 2027
Visit: Barbados, Saint Lucia, Saint Vincent, Curacao, Colombia, Panama
Select Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,363
Suite
$13,590
From
US$11,363
Save 1,067
Per Person
View Trip
20 Day Southern America & Panama Canal Cruise: Lima, Panama City & Cozumel with Azamara Cruises
Cruise
 (3)

20 Days (19 Nights) Santiago to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 10 March 2027
Visit: Chile, Peru, Panama, Costa Rica, Colombia, Mexico, USA
Azamara Always Included
Inside
$6,529
Oceanview
$7,339
Balcony
$7,879
Suite
$13,089
From
US$6,529
Per Person
View Trip
19 Day Valparaiso to Miami with Silversea
Cruise
 (1)

19 Days (18 Nights) Valparaiso to Miami
Cruise Line: Silversea
Ship: Silver Nova
Departure: 05 March 2027
Visit: Chile, Peru, Ecuador, Panama, Mexico, USA
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$16,500
Suite
$22,000
From
US$16,500
Per Person
View Trip
13 Day Miami, Fl to Lima (Callao) with Silversea
Cruise

13 Days (12 Nights) Miami to Lima
Cruise Line: Silversea
Ship: Silver Ray
Departure: 15 January 2028
Visit: USA, Mexico, Costa Rica, Panama, Ecuador, Peru
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$11,100
Suite
$16,900
From
US$11,100
Per Person
View Trip
37 Day New York To Sydney with Cunard
Cruise
 (1)

37 Days (36 Nights) New York to Sydney
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 19 January 2027
Visit: USA, Aruba, Panama, El Salvador (+4 more), Mexico, Fiji, New Caledonia, Australia
Bonus Onboard Credit
Inside
$6,419
Oceanview
$6,659
Balcony
$8,749
Suite
-
From
US$6,419
Per Person
View Trip
20 Day Panama, Peru & Chile Cruise: Panama Canal, Lima & Coquimbo with Azamara Cruises
Cruise
 (5)

20 Days (19 Nights) Miami to Valparaiso
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+5 more), Costa Rica, Panama, Ecuador, Peru, Chile
Azamara Always Included
Inside
$6,249
Oceanview
$7,069
Balcony
$8,579
Suite
$12,279
From
US$6,249
Per Person
View Trip
17 Day Machu Picchu & Mayan Ruins with Regent Seven Seas
Cruise

17 Days (16 Nights) Lima to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 10 March 2027
Visit: Peru, Ecuador, Costa Rica, Panama (+4 more), Honduras, Belize, Mexico, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,899
Suite
$16,899
From
US$15,899
Save 15,899
Per Person
View Trip
29 Day Seattle To Miami with Cunard
Cruise
 (13)

29 Days (28 Nights) Seattle to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 17 September 2026
Visit: USA, Canada, Mexico, Guatemala, Panama, Curacao, Aruba
Bonus Onboard Credit
Inside
$2,681
Oceanview
$3,024
Balcony
$4,621
Suite
$14,163
From
US$2,681
Per Person
View Trip
41 Day Seattle To Miami with Cunard
Cruise
 (13)

41 Days (40 Nights) Seattle to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 17 September 2026
Visit: USA, Canada, Mexico, Guatemala (+9 more), Panama, Curacao, Aruba, Puerto Rico, Antigua and Barbuda, Saint Lucia, Barbados, Saint Martin, Virgin Islands
Bonus Onboard Credit
Inside
$3,620
Oceanview
$4,169
Balcony
$6,090
Suite
$14,641
From
US$3,620
Per Person
View Trip
26 Day Los Angeles To Southampton with Cunard
Cruise

26 Days (25 Nights) Los Angeles to London
Cruise Line: Cunard
Ship: Queen Anne
Departure: 05 April 2026
Visit: USA, Guatemala, Panama, Curacao, Aruba, Portugal, England
Inside
-
Oceanview
-
Balcony
$6,699
Suite
-
From
US$6,699
Per Person
View Trip
34 Day Sydney To Miami with Cunard
Cruise
 (13)

34 Days (33 Nights) Sydney to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 25 March 2028
Visit: Australia, Tonga, USA, Mexico, Costa Rica, Panama, Aruba
Inside
$6,979
Oceanview
$8,179
Balcony
$10,179
Suite
$24,079
From
US$6,979
Per Person
View Trip
50 Day Yokohama To Miami with Cunard
Cruise
 (13)

50 Days (49 Nights) Tokyo to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 09 March 2028
Visit: Japan, Papua New Guinea, Australia, Tonga (+5 more), USA, Mexico, Costa Rica, Panama, Aruba
Inside
$9,919
Oceanview
$11,819
Balcony
$14,819
Suite
$34,419
From
US$9,919
Per Person
View Trip
46 Day World Cruise: South Pacific & Panama Canal with Seabourn
Cruise
 (1)

46 Days (45 Nights) Brisbane to Miami
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 15 April 2027
Visit: Australia, New Caledonia, Vanuatu, Fiji (+7 more), Samoa, USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Yours to Explore
Inside
-
Oceanview
$22,749
Balcony
$25,099
Suite
$52,099
From
US$22,749
Per Person
View Trip
35 Day Hamburg To Rio De Janeiro with Cunard
Cruise

35 Days (34 Nights) Hamburg to Rio de Janeiro
Cruise Line: Cunard
Ship: Queen Anne
Departure: 05 January 2027
Visit: Germany, Holland, Belgium, England (+5 more), Bermuda, USA, Turks and Caicos Islands, Barbados, Brazil
Bonus Onboard Credit
Inside
$5,369
Oceanview
$7,749
Balcony
$8,769
Suite
$18,599
From
US$5,369
Per Person
View Trip
29 Day Caribbean, Central America & Peru Cruise: Aruba, Miami & Panama Canal with Azamara Cruises
Cruise
 (5)

29 Days (28 Nights) Bridgetown to Valparaiso
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 27 December 2027
Visit: Barbados, Bonaire, Curacao, Aruba (+11 more), Dominican Republic, Bahamas, USA, Mexico, Belize, Honduras, Costa Rica, Panama, Ecuador, Peru, Chile
Azamara Always Included
Inside
$8,779
Oceanview
$10,339
Balcony
$12,599
Suite
$18,419
From
US$8,779
Per Person
View Trip
37 Day Caribbean To Cape Horn with Oceania Cruises
Cruise
 (1)

37 Days (36 Nights) Miami to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 19 December 2026
Visit: USA, Curacao, Aruba, Colombia (+7 more), Panama, Ecuador, Peru, Chile, Argentina, Falkland Islands, Uruguay
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$10,349
Oceanview
$10,999
Balcony
$15,649
Suite
-
From
US$10,349
Save 10,349
Per Person
View Trip
69 Day Miami To Bridgetown Grand Voyage with Azamara Cruises
Cruise
 (5)

69 Days (68 Nights) Miami to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+13 more), Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Inside
$23,309
Oceanview
$27,149
Balcony
$32,749
Suite
$47,269
From
US$23,309
Per Person
View Trip
41 Day Buenos Aires To Miami Grand Voyage with Azamara Cruises
Cruise
 (3)

41 Days (40 Nights) Buenos Aires to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 17 February 2027
Visit: Argentina, Uruguay, Falkland Islands, Antarctica (+7 more), Chile, Peru, Panama, Costa Rica, Colombia, Mexico, USA
Azamara Always Included
Inside
$16,979
Oceanview
$16,979
Balcony
$20,529
Suite
$32,239
From
US$16,979
Per Person
View Trip
43 Day Miami To Buenos Aires Grand Voyage with Azamara Cruises
Cruise
 (5)

43 Days (42 Nights) Miami to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+9 more), Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Azamara Always Included
Inside
$14,709
Oceanview
$16,609
Balcony
$20,709
Suite
$29,119
From
US$14,709
Per Person
View Trip
29 Day Canal To Coral Reefs with Regent Seven Seas
Cruise

29 Days (28 Nights) Panama City to Tahiti
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 26 January 2027
Visit: Panama, Costa Rica, El Salvador, Guatemala, Mexico, USA, French Polynesia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$26,099
Suite
$26,599
From
US$26,099
Save 26,099
Per Person
View Trip
42 Day Miami To Auckland Grand Voyage with Azamara Cruises
Cruise
 (8)

42 Days (41 Nights) Miami to Auckland
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 05 January 2028
Visit: USA, Aruba, Curacao, Colombia (+7 more), Panama, Ecuador, Peru, Chile, Pitcairn Islands, French Polynesia, New Zealand
Azamara Always Included
Inside
-
Oceanview
$19,399
Balcony
$21,999
Suite
$34,499
From
US$19,399
Per Person
View Trip
36 Day San Diego To London Grand Voyage with Azamara Cruises
Cruise
 (5)

36 Days (35 Nights) San Diego to London
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 May 2027
Visit: USA, Mexico, Guatemala, El Salvador (+7 more), Costa Rica, Panama, Colombia, Canada, Ireland, England, France
Azamara Always Included
Inside
-
Oceanview
$11,439
Balcony
$12,429
Suite
$22,629
From
US$11,439
Per Person
View Trip
78 Day Circle South America Grand Voyage with Azamara Cruises
Cruise
 (5)

78 Days (77 Nights) Miami to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+19 more), Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados, Grenada, Saint Lucia, Martinique, Dominica, Saint Martin, Virgin Islands
Azamara Always Included
Inside
$25,989
Oceanview
$30,329
Balcony
$36,729
Suite
$53,229
From
US$25,989
Per Person
View Trip
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