Cruises From Santiago

Choose from 40 unique expeditions and cruises starting in Santiago, and travelling to Buenos Aires, Cape Town, Fort Lauderdale, Guayaquil, Lima and more. February is the most popular month to join a cruise from Santiago and you can select from 106 departures available from thirteen leading cruise lines.
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7 Days
33 Days
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40 Cruises (106 Cruise Departures)
33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
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Tour + Cruise
 (1)

33 Days Santiago to Lima
Operated By: Travelmarvel
Departures: Feb 2025 to Feb 2026
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay (+2 more), Brazil, Peru
Exclusive Deal
Save 1,546
From 16,955
18 Day South America & the Chilean Fjords with Viking Cruises
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Cruise
 (3)

18 Days (17 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Departures: Nov 2024 to Feb 2026
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$9,400
SUITE
$18,805
Save 1,120
From 9,400
16 Day Cape Horn & Strait of Magellan with Princess
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Cruise
 (3)

16 Days (15 Nights) Santiago to Buenos Aires
Cruise Line: Princess
Departure: 19 December 2024
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Deal
INSIDE
$5,148
OCEANVIEW
-
BALCONY
$6,989
SUITE
$7,296
From 5,148
31 Day Chilean Fjords, Glaciers & Antarctic Wildlife Explorer with Scenic
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Cruise

31 Days (30 Nights) Santiago to Buenos Aires
Cruise Line: Scenic
Departure: 04 November 2026
Countries Visited: Chile, Argentina, Falkland Islands, South Georgia Island (+1 more), Antarctica
Earlybird Saving
INSIDE
-
OCEANVIEW
-
BALCONY
$47,335
SUITE
$69,836
Save 22,445
From 47,335
20 Day Panama Canal & the Americas with Viking Cruises
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Cruise

20 Days (19 Nights) Santiago to New York
Cruise Line: Viking Cruises
Departures: Mar 2026 to Mar 2026
Countries Visited: Chile, Peru, Panama, Jamaica (+1 more), Bahamas
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$17,815
SUITE
$25,735
Save 1,180
From 17,815
14 Day The Emperor Penguins of Weddell Sea with Ponant
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Cruise

14 Days (13 Nights) Santiago to Santiago
Cruise Line: Ponant
Departures: Oct 2025 to Nov 2025
Countries Visited: Chile, Argentina, Antarctica
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$37,945
SUITE
$40,288
Save 796
From 37,945
13 Day Puerto Williams to Puerto Williams with Silversea
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Cruise

13 Days (12 Nights) Santiago to Santiago
Cruise Line: Silversea
Departures: Feb 2025 to Jan 2026
Countries Visited: Chile, Antarctica
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$24,799
Save 1,021
From 24,799
16 Day King George Island to Puerto Williams with Silversea
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Cruise

16 Days (15 Nights) Santiago to Santiago
Cruise Line: Silversea
Departure: 06 January 2025
Countries Visited: Chile, Antarctica, South Georgia Island, Falkland Islands
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$47,569
Save 1,231
From 47,569
22 Day Puerto Williams to Cape Town with Silversea
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Cruise

22 Days (21 Nights) Santiago to Cape Town
Cruise Line: Silversea
Ship: Silver Wind
Departure: 16 March 2026
Countries Visited: Chile, Falkland Islands, South Georgia Island, South Africa
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$15,790
BALCONY
$16,384
SUITE
$24,601
Save 910
From 15,790
16 Day Puerto Williams to Puerto Williams with Silversea
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Cruise

16 Days (15 Nights) Santiago to Santiago
Cruise Line: Silversea
Ship: Silver Wind
Departure: 07 February 2026
Countries Visited: Chile, South Georgia Island, Antarctica
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$26,878
BALCONY
$29,848
SUITE
$46,480
Save 1,022
From 26,878
22 Day Puerto Williams to Buenos Aires with Silversea
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Cruise

22 Days (21 Nights) Santiago to Buenos Aires
Cruise Line: Silversea
Departure: 10 March 2025
Countries Visited: Chile, Argentina, Falkland Islands, Antarctica
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$32,719
Save 1,081
From 32,719
23 Day Puerto Williams to Valparaiso with Silversea
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Cruise

23 Days (22 Nights) Santiago to Valparaiso
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 06 March 2026
Countries Visited: Chile, Argentina, Antarctica
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$24,898
BALCONY
$29,254
SUITE
$49,450
Save 1,002
From 24,898
19 Day Puerto Williams to Puerto Williams with Silversea
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Cruise

19 Days (18 Nights) Santiago to Santiago
Cruise Line: Silversea
Ship: Silver Wind
Departures: Dec 2024 to Dec 2025
Countries Visited: Chile, Falkland Islands, South Georgia Island, Antarctica
Mutiple Deals Available
INSIDE
-
OCEANVIEW
$30,343
BALCONY
$33,115
SUITE
$51,727
Save 1,103
From 30,343
32 Day San Antonio To Southampton with Cunard
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Cruise

32 Days (31 Nights) Santiago to London
Cruise Line: Cunard
Departure: 25 February 2025
Countries Visited: Chile, Peru, Ecuador, Panama (+6 more), Aruba, Bahamas, USA, Bermuda, Portugal, England
Exclusive Deal
INSIDE
$7,237
OCEANVIEW
$8,524
BALCONY
$11,098
SUITE
$25,552
From 7,237
23 Day In-depth Antarctica & Patagonia Expedition (Northbound) with Hurtigruten
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Cruise

23 Days (22 Nights) Santiago to Valparaiso
Cruise Line: Hurtigruten
Ship: MS Fram
Departure: 15 March 2025
Countries Visited: Chile, Antarctica
Exclusive Deal
INSIDE
$21,609
OCEANVIEW
$25,574
BALCONY
-
SUITE
$64,968
Save 3,752
From 21,609
7 Day King George Island to King George Island with Silversea
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Cruise

7 Days (6 Nights) Santiago to Santiago
Cruise Line: Silversea
Ship: Silver Wind
Departures: Jan 2026 to Jan 2026
Countries Visited: Chile, Antarctica
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$24,106
BALCONY
$28,066
SUITE
$48,856
Save 994
From 24,106
17 Day Edge Of The World Expedition with Regent Seven Seas
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Cruise

17 Days (16 Nights) Santiago to Buenos Aires
Cruise Line: Regent Seven Seas
Departure: 01 February 2026
Countries Visited: Chile, Argentina, Uruguay
Land Package Credit
INSIDE
-
OCEANVIEW
-
BALCONY
$18,481
SUITE
$20,115
Save 8,169
From 18,481
29 Day Ultimate South America with Santiago Stopover & Galapagos Cruise with Cosmos
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Tour + Cruise

29 Days Santiago to Guayaquil
Operated By: Cosmos
Departures: Sep 2024 to Nov 2024
Countries Visited: Chile, Brazil, Argentina, Peru (+2 more), Ecuador, Galapagos
Exclusive Savings
From 15,361
14 Day Patagonian Shores & Chilean Fjords with Viking Cruises
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Cruise

14 Days (13 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Departure: 11 November 2024
Countries Visited: Chile, Argentina
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$9,895
SUITE
$16,825
Save 6,100
From 9,895
19 Day Puerto Williams to Puerto Williams with Silversea
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Cruise

19 Days (18 Nights) Santiago to Santiago
Cruise Line: Silversea
Departures: Oct 2024 to Feb 2026
Countries Visited: Chile, Falkland Islands, South Georgia Island, Antarctica
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$36,283
Save 1,278
From 36,283
13 Day Chilean Fjords & Scenic Shores with Viking Cruises
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Cruise

13 Days (12 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Departures: Nov 2024 to Oct 2025
Countries Visited: Chile, Argentina
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$8,905
SUITE
$15,340
Save 6,090
From 8,905
16 Day In the Wake of Jean-Baptiste Charcot with Ponant
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Cruise

16 Days (15 Nights) Santiago to Santiago
Cruise Line: Ponant
Departures: Dec 2025 to Jan 2026
Countries Visited: Chile, Argentina, Antarctica
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$35,273
SUITE
$37,449
Save 697
From 35,273
13 Day Puerto Williams to Puerto Williams with Silversea
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Cruise

13 Days (12 Nights) Santiago to Santiago
Cruise Line: Silversea
Ship: Silver Wind
Departure: 04 March 2026
Countries Visited: Chile, Antarctica
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$20,245
BALCONY
$21,928
SUITE
$35,986
Save 955
From 20,245
18 Day San Antonio To Fort Lauderdale with Cunard
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Cruise

18 Days (17 Nights) Santiago to Fort Lauderdale
Cruise Line: Cunard
Departure: 25 February 2025
Countries Visited: Chile, Peru, Ecuador, Panama (+3 more), Aruba, Bahamas, USA
Exclusive Deal
INSIDE
$4,509
OCEANVIEW
$5,351
BALCONY
$6,935
SUITE
$16,340
From 4,509
19 Day Puerto Williams to Puerto Williams with Silversea
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Cruise

19 Days (18 Nights) Santiago to Santiago
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 08 November 2025
Countries Visited: Chile, Falkland Islands, South Georgia Island, Antarctica
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$31,630
BALCONY
$34,402
SUITE
$56,083
Save 1,070
From 31,630
11 Day Puerto Williams to Ushuaia with Silversea
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Cruise

11 Days (10 Nights) Santiago to Ushuaia
Cruise Line: Silversea
Ship: Silver Cloud
Departures: Mar 2025 to Mar 2026
Countries Visited: Chile, Antarctica, Argentina
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
$17,919
BALCONY
$19,998
SUITE
$29,799
From 17,919
23 Day In-depth Antarctica, Falklands & South Georgia Expedition with Hurtigruten
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Cruise

23 Days (22 Nights) Santiago to Santiago
Cruise Line: Hurtigruten
Ship: MS Fram
Departures: Nov 2024 to Feb 2026
Countries Visited: Chile, Falkland Islands, South Georgia Island, Antarctica
Exclusive Deal
INSIDE
-
OCEANVIEW
$27,699
BALCONY
-
SUITE
$36,827
Save 11,863
From 27,699
13 Day Journey to Antarctica: The White Continent with Collette
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Tour + Cruise

13 Days Santiago to Santiago
Operated By: Collette
Departure: 18 February 2025
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Chile, Argentina, Antarctica
Exclusive Savings
Save 468
From 25,591
11 Day Puerto Williams to Puerto Williams with Silversea
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Cruise

11 Days (10 Nights) Santiago to Santiago
Cruise Line: Silversea
Ship: Silver Wind
Departures: Dec 2024 to Feb 2026
Countries Visited: Chile, Antarctica
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$18,958
BALCONY
$21,334
SUITE
$28,660
Save 974
From 18,958
19 Day Isles Of Wonder with Regent Seven Seas
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Cruise

19 Days (18 Nights) Santiago to Papeete
Cruise Line: Regent Seven Seas
Departure: 16 February 2025
Countries Visited: Chile, Easter Island, French Polynesia
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$19,231
SUITE
$22,181
Save 4,279
From 19,231
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