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Cruises from USA to Chile

Are you looking for a cruise from USA to Chile? November and October are the most popular months to cruise between USA and Chile and there are 15 departures available from six of the world's leading cruise lines.
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17 Days
127 Days
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9 Cruises (15 Cruise Departures)
20 Day Panama Canal & the Americas with Viking Cruises
Cruise
 (1)

20 Days (19 Nights) New York to Santiago
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Oct 2026 to Oct 2029
Visit: USA, Bahamas, Jamaica, Panama, Peru, Chile
Flights Included
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,995
Suite
$14,995
From
US$8,995
Save 2,000
Per Person
View Trip
22 Day Inca Coast Discovery Segment with Holland America
Cruise
 (3)

22 Days (21 Nights) San Diego to Santiago
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 12 October 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Ecuador, Peru, Chile
Book Early & Have It All Fare Option
Inside
$2,884
Oceanview
$3,164
Balcony
$4,434
Suite
$7,164
From
US$2,884
Per Person
View Trip
20 Day Panama, Peru & Chile Cruise: Panama Canal, Lima & Coquimbo with Azamara Cruises
Cruise
 (5)

20 Days (19 Nights) Miami to Valparaiso
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+5 more), Costa Rica, Panama, Ecuador, Peru, Chile
Azamara Always Included
Inside
$6,249
Oceanview
$7,069
Balcony
$8,579
Suite
$12,279
From
US$6,249
Per Person
View Trip
127 Day World Cruise: Australia & South Pacific Panorama with Seabourn
Cruise
 (1)

127 Days (126 Nights) Miami to Los Angeles
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 January 2027
Visit: USA, Panama, Ecuador, Peru (+11 more), Chile, French Polynesia, Cook Islands, Tonga, New Zealand, Australia, Papua New Guinea, New Caledonia, Vanuatu, Fiji, Samoa
Inside
-
Oceanview
$75,399
Balcony
$90,099
Suite
$185,409
From
US$75,399
Per Person
View Trip
34 Day Brazilian & Cape Horn Grand Adventure with Princess
Cruise
 (8)

34 Days (33 Nights) Fort Lauderdale to Santiago
Cruise Line: Princess
Ship: Majestic Princess
Departure: 19 November 2026
Visit: USA, Saint Martin, Saint Lucia, Barbados (+5 more), Brazil, Uruguay, Argentina, Falkland Islands, Chile
Princess Standard
Inside
$4,153
Oceanview
-
Balcony
$4,294
Suite
$14,025
From
US$4,153
Per Person
View Trip
17 Day Inca & Panama Canal Discovery: Lima Overnight with Holland America
Cruise
 (3)

17 Days (16 Nights) Fort Lauderdale to Santiago
Cruise Line: Holland America
Ship: Oosterdam
Departure: 18 November 2026
Visit: USA, Cayman Islands, Panama, Ecuador, Peru, Chile
Fare Saver
Inside
$2,099
Oceanview
$2,199
Balcony
$3,199
Suite
$4,299
From
US$2,099
Per Person
View Trip
27 Day Inca Coast: Mexico & Latin America Legendary Voyage with Holland America
Cruise
 (3)

27 Days (26 Nights) Vancouver to Santiago
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 07 October 2027
Visit: Canada, USA, Mexico, Guatemala (+4 more), Costa Rica, Ecuador, Peru, Chile
Book Early & Have It All Fare Option
Inside
$3,309
Oceanview
$3,609
Balcony
$5,009
Suite
$7,909
From
US$3,309
Per Person
View Trip
38 Day Fort Lauderdale To San Antonio with Cunard
Cruise

38 Days (37 Nights) Fort Lauderdale to Santiago
Cruise Line: Cunard
Ship: Queen Anne
Departure: 22 January 2027
Visit: USA, Turks and Caicos Islands, Barbados, Brazil, Uruguay, Argentina, Chile
Bonus Onboard Credit
Inside
$6,799
Oceanview
$9,429
Balcony
$10,423
Suite
$21,539
From
US$6,799
Per Person
View Trip
18 Day Panama & Scenic South America with Viking Cruises
Cruise

18 Days (17 Nights) Fort Lauderdale to Santiago
Cruise Line: Viking Cruises
Ship: Viking Octantis
Departure: 06 November 2026
Visit: USA, Mexico, Panama, Ecuador, Peru, Chile
Viking $999 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,995
Suite
$14,995
From
US$8,995
Save 1,000
Per Person
View Trip
Results: 9 results

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Country Routes

Cruises from Canada to USA Cruises from USA to Chile Cruises from USA to Panama Cruises from USA to Peru

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