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Cruises from San Diego

Choose from 79 unique cruises starting in San Diego, and traveling to Buenos Aires, Fort Lauderdale, London, Miami, Santiago and more. January is the most popular month to join a cruise from San Diego and you can select from 142 departures available from five leading cruise lines.
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79 Cruises (142 Cruise Departures)
15 Day Mexican Riviera & Baja Peninsula with Holland America
Cruise
 (2)

15 Days (14 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 26 December 2026
Visit: USA, Mexico
Fare Saver
Inside
$1,894
Oceanview
$2,114
Balcony
$2,704
Suite
$4,027
From
US$1,894
Per Person
View Trip
36 Day Hawaii, Tahiti & Marquesas Legendary Voyage with Holland America
Cruise
 (3)

36 Days (35 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 14 October 2027
Visit: USA, Kiribati, French Polynesia
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$4,267
Oceanview
$4,855
Balcony
$10,539
Suite
$19,065
From
US$4,267
Per Person
View Trip
31 Day Circle Hawaii & Sea Of Cortez with Holland America
Cruise
 (3)

31 Days (30 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 18 November 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$3,694
Oceanview
$4,111
Balcony
$7,786
Suite
$14,539
From
US$3,694
Per Person
View Trip
15 Day Baja Peninsula & Classic California Coast with Holland America
Cruise
 (3)

15 Days (14 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 06 November 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$1,914
Oceanview
$2,394
Balcony
$2,694
Suite
$3,501
From
US$1,914
Per Person
View Trip
36 Day Hawaii, Tahiti & Marquesas Legendary Voyage with Holland America
Cruise
 (2)

36 Days (35 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 19 February 2028
Visit: USA, Kiribati, French Polynesia
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$4,460
Oceanview
$5,734
Balcony
$7,008
Suite
$8,968
From
US$4,460
Per Person
View Trip
14 Day Historical Baja Peninsula with Holland America
Cruise
 (3)

14 Days (13 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 04 April 2027
Visit: USA, Mexico
Fare Saver
Inside
$1,399
Oceanview
$1,599
Balcony
$3,248
Suite
$6,090
From
US$1,399
Per Person
View Trip
29 Day Mexico Riviera, Pacific Coastal & Circle Hawaii with Holland America
Cruise
 (2)

29 Days (28 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Koningsdam
Departure: 01 April 2028
Visit: USA, Mexico, Canada
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$3,719
Oceanview
$4,885
Balcony
$5,493
Suite
$7,443
From
US$3,719
Per Person
View Trip
11 Day Mexican Riviera & Sea Of Cortez with Holland America
Cruise
 (2)

11 Days (10 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departures: Nov 2026 to Nov 2027
Visit: USA, Mexico
Fare Saver
Book Early & Have It All Fare Option
Inside
$899
Oceanview
$1,049
Balcony
$1,349
Suite
$2,299
From
US$899
Per Person
View Trip
25 Day Mexican Riviera & Circle Hawaii with Holland America
Cruise
 (2)

25 Days (24 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 08 January 2028
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$3,174
Oceanview
$4,064
Balcony
$4,622
Suite
$6,435
From
US$3,174
Per Person
View Trip
8 Day Mexican Riviera with Holland America
Cruise
 (2)

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ships: Koningsdam, Zaandam
Departures: Dec 2026 to Dec 2027
Visit: USA, Mexico
Fare Saver
Book Early & Have It All Fare Option
Inside
$899
Oceanview
$999
Balcony
$1,699
Suite
$2,549
From
US$899
Per Person
View Trip
8 Day Mexican Riviera with Holland America
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zuiderdam
Departure: 16 January 2027
Visit: USA, Mexico
Fare Saver
Inside
$849
Oceanview
$949
Balcony
$1,249
Suite
$2,399
From
US$849
Per Person
View Trip
8 Day Pacific Coastal Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to Vancouver
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 May 2027
Visit: USA, Canada
Bonus Onboard Credit
Exclusive Savings
Inside
$646
Oceanview
$665
Balcony
$918
Suite
$1,968
From
US$646
Save 326
Per Person
View Trip
13 Day Mexican Riviera Holiday with Holland America
Cruise
 (2)

13 Days (12 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 18 December 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$1,954
Oceanview
$2,384
Balcony
$2,814
Suite
$3,840
From
US$1,954
Per Person
View Trip
12 Day Mexican Riviera & Sea Of Cortez with Holland America
Cruise
 (3)

12 Days (11 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 07 April 2026
Visit: USA, Mexico
Have It All Fare Option
Inside
$1,254
Oceanview
$1,354
Balcony
$3,103
Suite
-
From
US$1,254
Per Person
View Trip
17 Day Panama Canal with Holland America
Cruise
 (3)

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 02 October 2026
Visit: USA, Mexico, Guatemala, El Salvador, Panama, Colombia, Bahamas
Fare Saver
Inside
$1,729
Oceanview
$1,789
Balcony
$2,859
Suite
$4,862
From
US$1,729
Per Person
View Trip
19 Day Circle Hawaii with Holland America
Cruise
 (3)

19 Days (18 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 18 November 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$2,334
Oceanview
$2,634
Balcony
$4,951
Suite
$9,557
From
US$2,334
Per Person
View Trip
12 Day Mexican Riviera & Sea Of Cortez with Holland America
Cruise
 (2)

12 Days (11 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departures: Oct 2026 to Dec 2026
Visit: USA, Mexico
Fare Saver
Inside
$949
Oceanview
$1,099
Balcony
$1,449
Suite
$2,449
From
US$949
Per Person
View Trip
12 Day Mexican Riviera & Pacific Coast with Holland America
Cruise
 (3)

12 Days (11 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ships: Koningsdam, Zaandam
Departures: Apr 2026 to Apr 2028
Visit: USA, Mexico, Canada
Multiple Deals Available
Inside
$954
Oceanview
$1,004
Balcony
$1,899
Suite
$2,599
From
US$954
Per Person
View Trip
16 Day Panama Canal with Holland America
Cruise
 (3)

16 Days (15 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Zaandam
Departure: 19 December 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Fare Saver
Inside
$1,999
Oceanview
$2,099
Balcony
$4,627
Suite
-
From
US$1,999
Per Person
View Trip
19 Day Circle Hawaii Holiday with Holland America
Cruise
 (3)

19 Days (18 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 19 November 2026
Visit: USA, Mexico
Fare Saver
Inside
$1,699
Oceanview
$1,799
Balcony
$4,329
Suite
-
From
US$1,699
Per Person
View Trip
10 Day Mexican Riviera Holiday with Holland America
Cruise
 (2)

10 Days (9 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 30 December 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$1,584
Oceanview
$1,984
Balcony
$2,284
Suite
$3,228
From
US$1,584
Per Person
View Trip
8 Day Wine Country & Pacific Northwest with Holland America
Cruise
 (3)

8 Days (7 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Zaandam
Departure: 17 April 2027
Visit: USA, Canada
Fare Saver
Inside
$799
Oceanview
$899
Balcony
$2,249
Suite
$3,194
From
US$799
Per Person
View Trip
8 Day Mexican Riviera with Holland America
Cruise
 (3)

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ships: Koningsdam, Zaandam
Departures: Apr 2026 to Apr 2028
Visit: USA, Mexico
Have It All Fare Option
Fare Saver
Book Early & Have It All Fare Option
Inside
$769
Oceanview
$799
Balcony
$1,389
Suite
$1,839
From
US$769
Per Person
View Trip
17 Day Mexican Riviera Holiday with Holland America
Cruise
 (2)

17 Days (16 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 23 December 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$2,729
Oceanview
$3,387
Balcony
$3,906
Suite
$5,533
From
US$2,729
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$411
Oceanview
$453
Balcony
$501
Suite
$714
From
US$411
Save 245
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Dec 2026 to Apr 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$348
Oceanview
$395
Balcony
$469
Suite
$618
From
US$348
Save 226
Per Person
View Trip
36 Day San Diego To London Grand Voyage with Azamara Cruises
Cruise
 (5)

36 Days (35 Nights) San Diego to London
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 May 2027
Visit: USA, Mexico, Guatemala, El Salvador (+7 more), Costa Rica, Panama, Colombia, Canada, Ireland, England, France
Azamara Always Included
Exclusive Savings
Inside
-
Oceanview
$11,188
Balcony
$12,148
Suite
$22,042
From
US$11,188
Save 251
Per Person
View Trip
17 Day Panama Canal with Holland America
Cruise

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Eurodam
Departures: Oct 2026 to Oct 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Fare Saver
Book Early & Have It All Fare Option
Inside
$1,809
Oceanview
$1,859
Balcony
$2,919
Suite
$5,155
From
US$1,809
Per Person
View Trip
18 Day Circle Hawaii with Holland America
Cruise
 (2)

18 Days (17 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 15 January 2028
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$2,284
Oceanview
$3,034
Balcony
$3,429
Suite
$4,752
From
US$2,284
Per Person
View Trip
12 Day Mexican Riviera & Sea Of Cortez with Holland America
Cruise
 (2)

12 Days (11 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 07 December 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$1,354
Oceanview
$1,704
Balcony
$2,004
Suite
$2,604
From
US$1,354
Per Person
View Trip
Results: 1-30 of 79

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Trip Lengths

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Departure Months

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Cities

Amsterdam Anchorage Baltimore Boston Cape Liberty Fort Lauderdale Galveston Honolulu Jacksonville Los Angeles Miami New Orleans New York Orlando Philadelphia San Diego San Francisco San Juan Seattle Seward Tampa Vancouver

Routes

Anchorage to Vancouver Baltimore to Baltimore Barcelona to Fort Lauderdale Barcelona to Miami Boston to Montreal Boston to Quebec City Boston to Boston Bridgetown to Miami Cape Liberty to Cape Liberty Fort Lauderdale to Los Angeles Fort Lauderdale to London Fort Lauderdale to Barcelona Fort Lauderdale to Fort Lauderdale Fort Lauderdale to San Diego Fort Lauderdale to Vancouver Galveston to Galveston Honolulu to Tahiti Honolulu to Vancouver Jacksonville to Jacksonville London to Fort Lauderdale London to New York Los Angeles to Miami Los Angeles to Vancouver Los Angeles to Los Angeles Miami to San Juan Miami to Lisbon Miami to Los Angeles Miami to Rome Miami to Bridgetown Miami to Panama City Miami to Barcelona Miami to Miami Miami to London Montreal to Boston Montreal to Miami Montreal to New York New Orleans to New Orleans New York to Montreal New York to New York New York to London Orlando to Orlando Panama City to Miami Philadelphia to Philadelphia Quebec City to Boston Rome to Fort Lauderdale Rotterdam to Fort Lauderdale San Diego to Fort Lauderdale San Diego to Vancouver San Diego to San Diego San Francisco to San Francisco San Juan to Miami Seattle to Vancouver Seattle to Seattle Seward to Vancouver Sydney to Honolulu Tahiti to Honolulu Tampa to Tampa Toronto to Boston Vancouver to Los Angeles Vancouver to Honolulu Vancouver to Seward Vancouver to Seattle Vancouver to Anchorage Vancouver to San Diego

Country Routes

Argentina to USA Australia to USA Barbados to USA Canada to USA Chile to USA Dominican Republic to USA England to USA French Polynesia to USA Greece to USA Holland to USA Iceland to USA Italy to USA Japan to USA New Zealand to USA Panama to USA Peru to USA Portugal to USA Puerto Rico to USA Spain to USA USA to Portugal USA to Germany USA to Iceland USA to Puerto Rico USA to Brazil USA to Dominican Republic USA to Argentina USA to Australia USA to Barbados USA to Canada USA to Chile USA to England USA to French Polynesia USA to Holland USA to Italy USA to Japan USA to Panama USA to Peru USA to Spain

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