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Cruises from San Diego

Choose from 75 unique cruises starting in San Diego, and traveling to Buenos Aires, Fort Lauderdale, London, Miami, Santiago and more. December and January are the most popular months to join a cruise from San Diego and you can select from 135 departures available from five leading cruise lines.
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75 Cruises (135 Cruise Departures)
15 Day Mexican Riviera & Baja Peninsula with Holland America
Cruise
 (2)

15 Days (14 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 26 December 2026
Visit: USA, Mexico
Fare Saver
Inside
$1,894
Oceanview
$2,114
Balcony
$2,704
Suite
$4,094
From
US$1,894
Per Person
View Trip
18 Day Circle Hawaii with Holland America
Cruise
 (2)

18 Days (17 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 15 January 2028
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$2,284
Oceanview
$3,034
Balcony
$3,484
Suite
$4,834
From
US$2,284
Per Person
View Trip
17 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

17 Days (16 Nights) San Diego to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Star
Departure: 13 February 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Inside
$2,109
Oceanview
$2,609
Balcony
$3,959
Suite
$4,359
From
US$2,109
Per Person
View Trip
17 Day Mexican Riviera Holiday with Holland America
Cruise
 (2)

17 Days (16 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 30 December 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$2,504
Oceanview
$3,124
Balcony
$3,554
Suite
$5,074
From
US$2,504
Per Person
View Trip
19 Day Circle Hawaii Holiday with Holland America
Cruise
 (3)

19 Days (18 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 19 November 2026
Visit: USA, Mexico
Fare Saver
Inside
$1,699
Oceanview
$1,799
Balcony
$4,299
Suite
-
From
US$1,699
Per Person
View Trip
36 Day Hawaii, Tahiti & Marquesas Legendary Voyage with Holland America
Cruise
 (2)

36 Days (35 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 19 February 2028
Visit: USA, Kiribati, French Polynesia
Book Early & Have It All Fare Option
Inside
$4,524
Oceanview
$5,824
Balcony
$7,124
Suite
$9,124
From
US$4,524
Per Person
View Trip
15 Day Mexican Riviera & Baja Peninsula with Holland America
Cruise
 (3)

15 Days (14 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departures: Dec 2026 to Mar 2027
Visit: USA, Mexico
Fare Saver
Inside
$1,749
Oceanview
$1,949
Balcony
$2,569
Suite
$3,689
From
US$1,749
Per Person
View Trip
5 Day Pacific Coastal Cruise with Holland America
Cruise

5 Days (4 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Eurodam
Departure: 20 April 2026
Visit: USA, Canada
Advantage Fare
Inside
$299
Oceanview
$319
Balcony
$369
Suite
-
From
US$299
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departure: 29 January 2027
Visit: USA, Mexico, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,567
Oceanview
$1,877
Balcony
$2,921
Suite
$3,777
From
US$1,567
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Dec 2026 to Apr 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$336
Oceanview
$389
Balcony
$488
Suite
$601
From
US$336
Save 196
Per Person
View Trip
16 Day Panama Canal with Holland America
Cruise
 (3)

16 Days (15 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Zaandam
Departure: 19 December 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Fare Saver
Inside
$1,899
Oceanview
$2,099
Balcony
$4,699
Suite
-
From
US$1,899
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 28 January 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$527
Oceanview
$642
Balcony
$802
Suite
$1,735
From
US$527
Save 349
Per Person
View Trip
7 Day Mexican Riviera From San Diego To San Diego with Norwegian Cruise Line
Cruise
 (1)

7 Days (6 Nights) San Diego to San Diego
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Star
Departure: 20 December 2026
Visit: USA, Mexico
Inside
$849
Oceanview
$999
Balcony
$1,199
Suite
$1,579
From
US$849
Per Person
View Trip
8 Day Classic California Coast with Holland America
Cruise
 (3)

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 13 November 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$1,069
Oceanview
$1,319
Balcony
$1,469
Suite
$1,919
From
US$1,069
Per Person
View Trip
15 Day Mexican Riviera & Baja Peninsula with Holland America
Cruise

15 Days (14 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zuiderdam
Departure: 16 January 2027
Visit: USA, Mexico
Fare Saver
Inside
$1,529
Oceanview
$1,709
Balcony
$2,249
Suite
$4,139
From
US$1,529
Per Person
View Trip
8 Day Pacific Coastal Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to Vancouver
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 May 2027
Visit: USA, Canada
Bonus Onboard Credit
Exclusive Savings
Inside
$611
Oceanview
$620
Balcony
$970
Suite
$1,734
From
US$611
Save 347
Per Person
View Trip
8 Day Wine Country & Pacific Northwest with Holland America
Cruise
 (3)

8 Days (7 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Zaandam
Departure: 17 April 2027
Visit: USA, Canada
Fare Saver
Inside
$799
Oceanview
$899
Balcony
$2,249
Suite
$3,249
From
US$799
Per Person
View Trip
36 Day Hawaii, Tahiti & Marquesas with Holland America
Cruise
 (2)

36 Days (35 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 13 February 2027
Visit: USA, Kiribati, French Polynesia
Fare Saver
Inside
$4,009
Oceanview
$5,009
Balcony
$6,809
Suite
$10,609
From
US$4,009
Per Person
View Trip
31 Day Circle Hawaii & Sea Of Cortez with Holland America
Cruise
 (3)

31 Days (30 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 19 November 2026
Visit: USA, Mexico
Fare Saver
Inside
$2,744
Oceanview
$2,934
Balcony
$6,724
Suite
-
From
US$2,744
Per Person
View Trip
13 Day Historical Baja Peninsula with Holland America
Cruise
 (3)

13 Days (12 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departures: Dec 2026 to Dec 2027
Visit: USA, Mexico
Fare Saver
Book Early & Have It All Fare Option
Inside
$999
Oceanview
$1,099
Balcony
$2,799
Suite
$5,864
From
US$999
Per Person
View Trip
5 Day Pacific Coastal Cruise with Holland America
Cruise
 (3)

5 Days (4 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ships: Koningsdam, Nieuw Amsterdam, Zaandam
Departures: May 2026 to Apr 2028
Visit: USA, Canada
Advantage Fare
Fare Saver
Book Early & Have It All Fare Option
Inside
$239
Oceanview
$259
Balcony
$674
Suite
$934
From
US$239
Per Person
View Trip
37 Day Inca Coast Discovery Collectors' Voyage with Holland America
Cruise
 (3)

37 Days (36 Nights) San Diego to Buenos Aires
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 12 October 2027
Visit: USA, Mexico, Guatemala, Costa Rica (+6 more), Ecuador, Peru, Chile, Argentina, Falkland Islands, Uruguay
Book Early & Have It All Fare Option
Inside
$4,719
Oceanview
$5,179
Balcony
$7,429
Suite
$11,259
From
US$4,719
Per Person
View Trip
19 Day Circle Hawaii with Holland America
Cruise
 (2)

19 Days (18 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 01 February 2028
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$2,379
Oceanview
$3,129
Balcony
$3,579
Suite
$4,929
From
US$2,379
Per Person
View Trip
31 Day Circle Hawaii & Sea Of Cortez with Holland America
Cruise
 (3)

31 Days (30 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 18 November 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$3,694
Oceanview
$4,164
Balcony
$7,914
Suite
$14,804
From
US$3,694
Per Person
View Trip
29 Day Mexico Riviera, Pacific Coastal & Circle Hawaii with Holland America
Cruise
 (2)

29 Days (28 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Koningsdam
Departure: 27 March 2027
Visit: USA, Mexico, Canada
Fare Saver
Inside
$2,984
Oceanview
$3,794
Balcony
$4,694
Suite
$7,164
From
US$2,984
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Mar 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$347
Oceanview
$407
Balcony
$459
Suite
$627
From
US$347
Save 200
Per Person
View Trip
16 Day Panama Canal with Holland America
Cruise

16 Days (15 Nights) San Diego to Miami
Cruise Line: Holland America
Ship: Zuiderdam
Departure: 30 January 2027
Visit: USA, Mexico, Guatemala, Panama, Colombia, Bahamas
Fare Saver
Inside
$1,899
Oceanview
$1,999
Balcony
$2,999
Suite
$4,599
From
US$1,899
Per Person
View Trip
16 Day Panama Canal Holiday with Holland America
Cruise
 (3)

16 Days (15 Nights) San Diego to Miami
Cruise Line: Holland America
Ship: Zaandam
Departure: 18 December 2027
Visit: USA, Mexico, Costa Rica, Panama, Colombia
Book Early & Have It All Fare Option
Inside
$2,674
Oceanview
$2,974
Balcony
$4,974
Suite
$9,574
From
US$2,674
Per Person
View Trip
25 Day Mexican Riviera & Circle Hawaii with Holland America
Cruise
 (2)

25 Days (24 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 08 January 2028
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$3,174
Oceanview
$4,124
Balcony
$4,694
Suite
$6,544
From
US$3,174
Per Person
View Trip
10 Day Mexican Riviera Holiday with Holland America
Cruise
 (2)

10 Days (9 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 30 December 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$1,584
Oceanview
$1,984
Balcony
$2,284
Suite
$3,284
From
US$1,584
Per Person
View Trip
Results: 1-30 of 75

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Trip Lengths

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Departure Months

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Cities

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Routes

Anchorage to Vancouver Baltimore to Baltimore Barcelona to Fort Lauderdale Barcelona to Miami Boston to Montreal Boston to Quebec City Boston to Boston Bridgetown to Miami Cape Liberty to Cape Liberty Fort Lauderdale to London Fort Lauderdale to Barcelona Fort Lauderdale to Fort Lauderdale Fort Lauderdale to San Diego Fort Lauderdale to Vancouver Galveston to Galveston Honolulu to Tahiti Honolulu to Vancouver Jacksonville to Jacksonville London to Fort Lauderdale London to New York Los Angeles to Miami Los Angeles to Vancouver Los Angeles to Los Angeles Miami to San Juan Miami to Lisbon Miami to Los Angeles Miami to Rome Miami to Bridgetown Miami to Panama City Miami to Barcelona Miami to Miami Miami to London Montreal to Boston Montreal to Miami Montreal to New York New Orleans to New Orleans New York to Montreal New York to New York New York to London Orlando to Orlando Panama City to Miami Philadelphia to Philadelphia Quebec City to Boston Rome to Fort Lauderdale Rotterdam to Fort Lauderdale San Diego to Fort Lauderdale San Diego to Vancouver San Diego to San Diego San Francisco to San Francisco San Juan to Miami Seattle to Vancouver Seattle to Seattle Seward to Vancouver Sydney to Honolulu Tahiti to Honolulu Tampa to Tampa Toronto to Boston Vancouver to Los Angeles Vancouver to Honolulu Vancouver to Seward Vancouver to Seattle Vancouver to Anchorage Vancouver to San Diego

Country Routes

Argentina to USA Australia to USA Barbados to USA Canada to USA Chile to USA Dominican Republic to USA England to USA France to USA French Polynesia to USA Greece to USA Holland to USA Iceland to USA Italy to USA Japan to USA New Zealand to USA Panama to USA Peru to USA Portugal to USA Puerto Rico to USA Spain to USA USA to Portugal USA to Germany USA to Iceland USA to Puerto Rico USA to Brazil USA to Dominican Republic USA to Argentina USA to Australia USA to Barbados USA to Canada USA to Chile USA to England USA to French Polynesia USA to Holland USA to Italy USA to Japan USA to Panama USA to Peru USA to Spain

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