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Cruises from San Diego

Choose from 62 unique cruises starting in San Diego, and traveling to Fort Lauderdale, London, Miami and Vancouver. December and January are the most popular months to join a cruise from San Diego and you can select from 130 departures available from five leading cruise lines.
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62 Cruises (130 Cruise Departures)
15 Day Mexican Riviera & Baja Peninsula with Holland America
Cruise
 (2)

15 Days (14 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 26 December 2026
Visit: USA, Mexico
Fare Saver
Inside
$1,934
Oceanview
$2,124
Balcony
$2,794
Suite
$4,282
From
US$1,934
Per Person
View Trip
8 Day Ensenada, Cabo & Mazatlan with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Feb 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$640
Oceanview
$800
Balcony
$939
Suite
$1,425
From
US$640
Save 378
Per Person
View Trip
36 Day San Diego To London Grand Voyage with Azamara Cruises
Cruise
 (4)

36 Days (35 Nights) San Diego to London
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 May 2027
Visit: USA, Mexico, Guatemala, El Salvador (+7 more), Costa Rica, Panama, Colombia, Canada, Ireland, England, France
Azamara Always Included
Exclusive Savings
Inside
-
Oceanview
$11,188
Balcony
$12,148
Suite
$22,042
From
US$11,188
Save 251
Per Person
View Trip
8 Day Classic California Coast with Holland America
Cruise
 (2)

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 14 November 2026
Visit: USA, Mexico
Fare Saver
Inside
$794
Oceanview
$994
Balcony
$1,244
Suite
$1,744
From
US$794
Per Person
View Trip
31 Day Circle Hawaii & Sea Of Cortez with Holland America
Cruise
 (3)

31 Days (30 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 19 November 2026
Visit: USA, Mexico
Fare Saver
Inside
$2,644
Oceanview
$2,844
Balcony
$7,267
Suite
-
From
US$2,644
Per Person
View Trip
15 Day Baja Peninsula, Wine Country And Pnw with Holland America
Cruise
 (3)

15 Days (14 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 28 March 2026
Visit: USA, Mexico, Canada
Have It All Fare Option
Inside
-
Oceanview
$2,034
Balcony
$2,754
Suite
-
From
US$2,034
Per Person
View Trip
11 Day Mexican Riviera & Sea Of Cortez with Holland America
Cruise
 (2)

11 Days (10 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departures: Nov 2026 to Nov 2027
Visit: USA, Mexico
Fare Saver
Book Early & Have It All Fare Option
Inside
$1,059
Oceanview
$1,259
Balcony
$1,659
Suite
$2,459
From
US$1,059
Per Person
View Trip
36 Day Hawaii, Tahiti & Marquesas Legendary Voyage with Holland America
Cruise
 (3)

36 Days (35 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 14 October 2027
Visit: USA, Kiribati, French Polynesia
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$4,267
Oceanview
$4,855
Balcony
$10,539
Suite
$19,065
From
US$4,267
Per Person
View Trip
19 Day Circle Hawaii with Holland America
Cruise
 (2)

19 Days (18 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 26 January 2027
Visit: USA, Mexico
Fare Saver
Inside
$1,929
Oceanview
$2,429
Balcony
$3,029
Suite
$4,552
From
US$1,929
Per Person
View Trip
8 Day Wine Country & Pacific Northwest with Holland America
Cruise
 (3)

8 Days (7 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Zaandam
Departure: 17 April 2027
Visit: USA, Canada
Fare Saver
Inside
$794
Oceanview
$829
Balcony
$2,244
Suite
$3,189
From
US$794
Per Person
View Trip
36 Day Hawaii, Tahiti & Marquesas Legendary Voyage with Holland America
Cruise
 (2)

36 Days (35 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 19 February 2028
Visit: USA, Kiribati, French Polynesia
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$4,460
Oceanview
$5,734
Balcony
$7,008
Suite
$8,968
From
US$4,460
Per Person
View Trip
16 Day Panama Canal with Holland America
Cruise

16 Days (15 Nights) San Diego to Miami
Cruise Line: Holland America
Ship: Zuiderdam
Departure: 30 January 2027
Visit: USA, Mexico, Guatemala, Panama, Colombia, Bahamas
Fare Saver
Inside
$2,124
Oceanview
$2,324
Balcony
$3,224
Suite
$4,750
From
US$2,124
Per Person
View Trip
18 Day Circle Hawaii with Holland America
Cruise
 (2)

18 Days (17 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 09 January 2027
Visit: USA, Mexico
Fare Saver
Inside
$1,894
Oceanview
$2,394
Balcony
$2,994
Suite
$4,518
From
US$1,894
Per Person
View Trip
3 Day Ensenada Cruise with Royal Caribbean
Cruise

3 Days (2 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 October 2026
Visit: USA, Mexico
Exclusive Savings
Inside
$316
Oceanview
$376
Balcony
$488
Suite
$746
From
US$316
Save 177
Per Person
View Trip
8 Day Mexican Riviera with Holland America
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zuiderdam
Departure: 16 January 2027
Visit: USA, Mexico
Fare Saver
Inside
$849
Oceanview
$949
Balcony
$1,249
Suite
$2,449
From
US$849
Per Person
View Trip
12 Day Mexican Riviera & Pacific Coast with Holland America
Cruise
 (3)

12 Days (11 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ships: Koningsdam, Zaandam
Departures: Apr 2026 to Apr 2028
Visit: USA, Mexico, Canada
Have It All Fare Option
Fare Saver
Book Early & Have It All Fare Option
Inside
$1,054
Oceanview
$1,154
Balcony
$1,904
Suite
$2,704
From
US$1,054
Per Person
View Trip
14 Day Historical Baja Peninsula with Holland America
Cruise
 (3)

14 Days (13 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 04 April 2027
Visit: USA, Mexico
Fare Saver
Inside
$1,554
Oceanview
$1,619
Balcony
$3,400
Suite
$6,242
From
US$1,554
Per Person
View Trip
8 Day Baja Peninsula & Sea Of Cortez with Holland America
Cruise
 (3)

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ships: Koningsdam, Nieuw Amsterdam (+2 more), Zaandam, Zuiderdam
Departures: Mar 2026 to Mar 2028
Visit: USA, Mexico
Have It All Fare Option
Fare Saver
Book Early & Have It All Fare Option
Inside
$649
Oceanview
$679
Balcony
$1,244
Suite
$1,839
From
US$649
Per Person
View Trip
19 Day Circle Hawaii with Holland America
Cruise
 (3)

19 Days (18 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 18 November 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$2,334
Oceanview
$2,634
Balcony
$4,951
Suite
$9,557
From
US$2,334
Per Person
View Trip
8 Day Mexican Riviera with Holland America
Cruise
 (3)

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ships: Koningsdam, Zaandam
Departures: Apr 2026 to Apr 2028
Visit: USA, Mexico
Have It All Fare Option
Fare Saver
Book Early & Have It All Fare Option
Inside
$799
Oceanview
$929
Balcony
$1,249
Suite
$1,749
From
US$799
Per Person
View Trip
8 Day Mexican Riviera with Holland America
Cruise
 (2)

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ships: Koningsdam, Zaandam
Departures: Dec 2026 to Dec 2027
Visit: USA, Mexico
Fare Saver
Book Early & Have It All Fare Option
Inside
$944
Oceanview
$979
Balcony
$1,704
Suite
$2,554
From
US$944
Per Person
View Trip
15 Day Baja Peninsula & Classic California Coast with Holland America
Cruise
 (3)

15 Days (14 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 06 November 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$1,914
Oceanview
$2,394
Balcony
$2,694
Suite
$3,501
From
US$1,914
Per Person
View Trip
8 Day Pacific Coastal Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to Vancouver
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 May 2027
Visit: USA, Canada
Bonus Onboard Credit
Exclusive Savings
Inside
$665
Oceanview
$685
Balcony
$858
Suite
$1,693
From
US$665
Save 335
Per Person
View Trip
15 Day Mexican Riviera with Holland America
Cruise
 (3)

15 Days (14 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 13 November 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$1,954
Oceanview
$2,414
Balcony
$2,734
Suite
$3,579
From
US$1,954
Per Person
View Trip
13 Day Historical Baja Peninsula with Holland America
Cruise
 (3)

13 Days (12 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departures: Dec 2026 to Dec 2027
Visit: USA, Mexico
Fare Saver
Book Early & Have It All Fare Option
Inside
$1,134
Oceanview
$1,194
Balcony
$3,134
Suite
$5,761
From
US$1,134
Per Person
View Trip
16 Day Panama Canal with Holland America
Cruise
 (3)

16 Days (15 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Zaandam
Departure: 19 December 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Fare Saver
Inside
$2,324
Oceanview
$2,374
Balcony
$4,652
Suite
-
From
US$2,324
Per Person
View Trip
15 Day Mexican Riviera & Baja Peninsula with Holland America
Cruise
 (3)

15 Days (14 Nights) San Diego to San Diego
Cruise Line: Holland America
Ships: Koningsdam, Zaandam
Departures: Apr 2026 to Mar 2027
Visit: USA, Mexico
Have It All Fare Option
Fare Saver
Inside
$1,649
Oceanview
$1,919
Balcony
$2,459
Suite
$3,631
From
US$1,649
Per Person
View Trip
36 Day Hawaii, Tahiti & Marquesas with Holland America
Cruise
 (2)

36 Days (35 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 13 February 2027
Visit: USA, Kiribati, French Polynesia
Fare Saver
Exclusive Savings
Inside
$4,077
Oceanview
$5,155
Balcony
$6,233
Suite
$22,501
From
US$4,077
Per Person
View Trip
7 Day Mexican Riviera - San Diego with Norwegian Cruise Line
Cruise
 (1)

7 Days (6 Nights) San Diego to San Diego
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Star
Departure: 20 December 2026
Visit: USA, Mexico
Inside
$1,029
Oceanview
$1,309
Balcony
$1,509
Suite
$1,906
From
US$1,029
Per Person
View Trip
18 Day Panama Canal & Latin America Cruise: Mexico, Costa Rica & Colombia with Azamara Cruises
Cruise
 (4)

18 Days (17 Nights) San Diego to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 May 2027
Visit: USA, Mexico, Guatemala, El Salvador, Costa Rica, Panama, Colombia
Azamara Always Included
Exclusive Savings
Inside
$5,994
Oceanview
$6,459
Balcony
$7,323
Suite
$12,017
From
US$5,994
Save 135
Per Person
View Trip
Results: 1-30 of 62

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Departure Months

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Cities

Amsterdam Anchorage Baltimore Boston Cape Liberty Fort Lauderdale Galveston Honolulu Jacksonville Los Angeles Miami New Orleans New York Orlando Philadelphia San Diego San Francisco San Juan Seattle Seward Tampa Vancouver

Routes

Anchorage to Vancouver Baltimore to Baltimore Barcelona to Fort Lauderdale Barcelona to Miami Boston to Montreal Boston to Quebec City Boston to Boston Bridgetown to Miami Cape Liberty to Cape Liberty Fort Lauderdale to Los Angeles Fort Lauderdale to Barcelona Fort Lauderdale to Fort Lauderdale Fort Lauderdale to San Diego Fort Lauderdale to Vancouver Galveston to Galveston Honolulu to Tahiti Honolulu to Vancouver Jacksonville to Jacksonville London to Fort Lauderdale London to New York Los Angeles to Vancouver Los Angeles to Los Angeles Miami to San Juan Miami to Lisbon Miami to Los Angeles Miami to Rome Miami to Bridgetown Miami to Panama City Miami to Barcelona Miami to Miami Miami to London Montreal to Boston Montreal to Miami Montreal to New York New Orleans to New Orleans New York to Montreal New York to New York New York to London Orlando to Orlando Philadelphia to Philadelphia Quebec City to Boston Rome to Miami Rome to Fort Lauderdale Rotterdam to Fort Lauderdale San Diego to Fort Lauderdale San Diego to Vancouver San Diego to San Diego San Francisco to San Francisco San Juan to Miami Seattle to Vancouver Seattle to Seattle Seward to Vancouver Sydney to Honolulu Tahiti to Honolulu Tampa to Tampa Vancouver to Los Angeles Vancouver to Honolulu Vancouver to Seward Vancouver to Seattle Vancouver to Anchorage Vancouver to San Diego

Country Routes

Argentina to USA Australia to USA Barbados to USA Canada to USA Chile to USA Dominican Republic to USA England to USA French Polynesia to USA Greece to USA Holland to USA Iceland to USA Italy to USA Japan to USA New Zealand to USA Panama to USA Peru to USA Portugal to USA Puerto Rico to USA Spain to USA USA to Portugal USA to Iceland USA to Puerto Rico USA to Brazil USA to Dominican Republic USA to Australia USA to Barbados USA to Canada USA to Chile USA to England USA to French Polynesia USA to Holland USA to Italy USA to Japan USA to Panama USA to Peru USA to Spain

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