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Cruises from Spain to USA

Are you looking for a cruise from Spain to USA? October is the most popular month to cruise between Spain and USA and there are 43 departures available from thirteen of the world's leading cruise lines.
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41 Cruises (43 Cruise Departures)
16 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

16 Days (15 Nights) Palma de Mallorca to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 30 October 2026
Visit: Spain, Portugal, Puerto Rico, USA
Inside
$802
Oceanview
$1,014
Balcony
$1,189
Suite
-
From
US$802
Per Person
View Trip
35 Day Cultural Crossing with Oceania Cruises
Cruise
 (1)

35 Days (34 Nights) Barcelona to New York
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 16 August 2027
Visit: Spain, Morocco, Gibraltar, Portugal (+8 more), France, Guernsey, England, Ireland, Northern Ireland, Iceland, Canada, USA
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$9,749
Oceanview
$10,199
Balcony
$14,749
Suite
$20,349
From
US$9,749
Save 9,749
Per Person
View Trip
15 Day Cultural Crossing With Andalusia with Holland America
Cruise
 (3)

15 Days (14 Nights) Barcelona to Fort Lauderdale
Cruise Line: Holland America
Ship: Oosterdam
Departure: 04 November 2026
Visit: Spain, Gibraltar, Bermuda, USA
Fare Saver
Inside
$869
Oceanview
$1,019
Balcony
$1,369
Suite
$3,119
From
US$869
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Barcelona to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 31 October 2026
Visit: Spain, Portugal, Puerto Rico, USA
Inside
$674
Oceanview
$834
Balcony
$1,053
Suite
$2,317
From
US$674
Per Person
View Trip
14 Day Transatlantic Cruise: Malaga, San Juan & Miami with Azamara Cruises
Cruise
 (5)

14 Days (13 Nights) Malaga to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 04 December 2026
Visit: Spain, Morocco, Puerto Rico, USA
Azamara Circle Member - Quarterly Saving
Azamara Always Included
Inside
-
Oceanview
-
Balcony
$2,759
Suite
$5,219
From
US$2,759
Per Person
View Trip
23 Day Flamenco To Flamingos with Oceania Cruises
Cruise
 (1)

23 Days (22 Nights) Barcelona to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 02 November 2026
Visit: Spain, Portugal, Puerto Rico, Bahamas, USA
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
$6,649
Balcony
$8,699
Suite
$21,049
From
US$6,649
Save 6,649
Per Person
View Trip
15 Day Spain & Bermuda Transatlantic with Celebrity Cruises
Cruise
 (2)

15 Days (14 Nights) Barcelona to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Eclipse
Departure: 10 November 2026
Visit: Spain, Gibraltar, Bermuda, USA
Exclusive Savings
Inside
$1,458
Oceanview
$1,413
Balcony
$1,766
Suite
-
From
US$1,413
Save 832
Per Person
View Trip
13 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

13 Days (12 Nights) Barcelona to Orlando
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 31 October 2027
Visit: Spain, Portugal, USA
Inside
$1,059
Oceanview
$1,659
Balcony
$1,709
Suite
$2,009
From
US$1,059
Per Person
View Trip
15 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

15 Days (14 Nights) Barcelona to Orlando
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 01 November 2026
Visit: Spain, Virgin Islands, Bahamas, USA
Inside
$929
Oceanview
-
Balcony
$1,229
Suite
$1,439
From
US$929
Per Person
View Trip
17 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

17 Days (16 Nights) Barcelona to Orlando
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Escape
Departure: 28 October 2026
Visit: Spain, France, Morocco, USA
Inside
$1,249
Oceanview
$1,549
Balcony
$1,959
Suite
$2,049
From
US$1,249
Per Person
View Trip
16 Day Fall Caribbean Passage with Oceania Cruises
Cruise
 (3)

16 Days (15 Nights) Barcelona to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 25 November 2026
Visit: Spain, Portugal, Puerto Rico, Dominican Republic, USA
Your World Inclusions
Exclusive Savings
Inside
$3,150
Oceanview
$4,087
Balcony
$4,125
Suite
$5,475
From
US$3,150
Save 5,248
Per Person
View Trip
48 Day Footsteps Of Columbus with Oceania Cruises
Cruise
 (1)

48 Days (47 Nights) Barcelona to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 02 November 2026
Visit: Spain, Portugal, Puerto Rico, Bahamas (+9 more), USA, Virgin Islands, Antigua and Barbuda, Saint Lucia, Trinidad and Tobago, Brazil, Barbados, Dominica, Saint Martin
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
$15,199
Balcony
$20,699
Suite
$48,299
From
US$15,199
Save 15,199
Per Person
View Trip
15 Day Spanish Isles & Transatlantic Miles with Virgin Voyages
Cruise
 (1)

15 Days (14 Nights) Barcelona to Miami
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 11 October 2026
Visit: Spain, Morocco, USA
Inside
$1,469
Oceanview
$1,666
Balcony
$1,806
Suite
$5,320
From
US$1,469
Per Person
View Trip
15 Day Spain to Miami Halloween Transatlantic with Virgin Voyages
Cruise
 (5)

15 Days (14 Nights) Barcelona to Miami
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departure: 24 October 2027
Visit: Spain, Portugal, USA
Inside
$1,386
Oceanview
$1,526
Balcony
$1,666
Suite
$6,050
From
US$1,386
Per Person
View Trip
15 Day Western Europe Passage with Princess
Cruise
 (7)

15 Days (14 Nights) Barcelona to Fort Lauderdale
Cruise Line: Princess
Ship: Sun Princess
Departure: 07 November 2027
Visit: Spain, Gibraltar, Portugal, USA
Princess Standard
Sanctuary Collection
Inside
$1,040
Oceanview
$1,389
Balcony
$1,919
Suite
$2,389
From
US$1,040
Per Person
View Trip
14 Day Transatlantic Cruise: Malaga To Miami with Azamara Cruises
Cruise
 (8)

14 Days (13 Nights) Malaga to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 09 December 2027
Visit: Spain, Morocco, Virgin Islands, USA
Azamara Always Included
Inside
$1,809
Oceanview
$2,219
Balcony
$3,419
Suite
$5,479
From
US$1,809
Per Person
View Trip
14 Day Barcelona To Miami with Cunard
Cruise
 (13)

14 Days (13 Nights) Barcelona to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 29 October 2027
Visit: Spain, USA
Value Fare
Inside
$2,109
Oceanview
$2,349
Balcony
$2,669
Suite
$6,389
From
US$2,109
Per Person
View Trip
18 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

18 Days (17 Nights) Barcelona to Galveston
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 14 October 2026
Visit: Spain, Portugal, Saint Martin, Dominican Republic, Jamaica, USA
Inside
$1,479
Oceanview
$1,799
Balcony
$2,049
Suite
$3,579
From
US$1,479
Per Person
View Trip
16 Day Spain & Bermuda Transatlantic with Celebrity Cruises
Cruise
 (2)

16 Days (15 Nights) Barcelona to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Eclipse
Departure: 08 November 2027
Visit: Spain, Morocco, Bermuda, USA
Exclusive Savings
Inside
$1,111
Oceanview
$1,524
Balcony
$1,506
Suite
$6,025
From
US$1,111
Save 623
Per Person
View Trip
16 Day Spanish Passage with Princess
Cruise
 (7)

16 Days (15 Nights) Barcelona to Fort Lauderdale
Cruise Line: Princess
Ship: Sun Princess
Departure: 31 October 2026
Visit: Spain, Gibraltar, USA
Princess Standard
Sanctuary Collection
Inside
$1,180
Oceanview
$1,300
Balcony
$1,660
Suite
$2,070
From
US$1,180
Per Person
View Trip
28 Day Spain And Eastern Caribbean with Cunard
Cruise
 (13)

28 Days (27 Nights) Barcelona to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 29 October 2027
Visit: Spain, USA, Virgin Islands, Saint Kitts and Nevis (+4 more), Grenada, Barbados, Saint Lucia, Saint Martin
Value Fare
Inside
$3,369
Oceanview
$4,009
Balcony
$4,849
Suite
$12,149
From
US$3,369
Per Person
View Trip
14 Day Atlantic Ocean Passage with Viking Cruises
Cruise
 (5)

14 Days (13 Nights) Barcelona to Fort Lauderdale
Cruise Line: Viking Cruises
Ships: Viking Sky, Viking Vesta
Departures: Dec 2026 to Dec 2027
Visit: Spain, Portugal, Sint Maarten, USA
Viking $799 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,099
Suite
$5,499
From
US$3,099
Save 100
Per Person
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

14 Days (13 Nights) Barcelona to Miami
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 31 October 2026
Visit: Spain, Portugal, Puerto Rico, USA
Inside
$615
Oceanview
$761
Balcony
$936
Suite
-
From
US$615
Per Person
View Trip
25 Day A Grand Journey of Vibrant Cultures, Mayan Marvels & Idyllic Beaches with Explora Journeys
Cruise

25 Days (24 Nights) Barcelona to Miami
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 01 November 2026
Visit: Spain, Portugal, Antigua and Barbuda, Anguilla (+6 more), Puerto Rico, USA, Mexico, Honduras, Belize, Bahamas
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$10,170
From
US$10,170
Per Person
View Trip
17 Day A Grand Journey Of Lively Culture & Stunning Beaches with Explora Journeys
Cruise

17 Days (16 Nights) Barcelona to Miami
Cruise Line: Explora Journeys
Ships: Explora II, Explora I
Departures: Nov 2026 to Nov 2027
Visit: Spain, Portugal, Antigua and Barbuda, Anguilla, Puerto Rico, USA
Inside
-
Oceanview
-
Balcony
-
Suite
$6,610
From
US$6,610
Per Person
View Trip
17 Day Maritime Magic To Miami with Regent Seven Seas
Cruise

17 Days (16 Nights) Barcelona to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 04 November 2027
Visit: Spain, Morocco, Puerto Rico, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,949
Suite
$14,199
From
US$13,949
Save 13,949
Per Person
View Trip
15 Day Moonlight Over Bermuda with Regent Seven Seas
Cruise

15 Days (14 Nights) Barcelona to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 26 October 2026
Visit: Spain, Portugal, Bermuda, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$11,799
From
US$11,799
Save 11,799
Per Person
View Trip
17 Day Spain & Bermuda Transatlantic with Celebrity Cruises
Cruise

17 Days (16 Nights) Barcelona to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departure: 29 October 2027
Visit: Spain, France, Morocco, Bermuda, USA
Exclusive Savings
Inside
$1,907
Oceanview
$2,014
Balcony
$2,583
Suite
$17,162
From
US$1,907
Save 1,086
Per Person
View Trip
15 Day Spain & Morocco Transatlantic with Royal Caribbean
Cruise

15 Days (14 Nights) Barcelona to Fort Lauderdale
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 01 November 2027
Visit: Spain, Morocco, USA
Bonus Onboard Credit
Exclusive Savings
Inside
$868
Oceanview
$1,088
Balcony
$1,470
Suite
$2,616
From
US$868
Save 447
Per Person
View Trip
16 Day Pathway To Sunshine with Oceania Cruises
Cruise

16 Days (15 Nights) Barcelona to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 17 November 2026
Visit: Spain, Morocco, Puerto Rico, USA
Memorial Day Sale
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,950
Suite
-
From
US$4,950
Save 6,048
Per Person
View Trip
Results: 1-30 of 41

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