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Cruises from Spain to USA

Are you looking for a cruise from Spain to USA? October is the most popular month to cruise between Spain and USA and there are 45 departures available from thirteen of the world's leading cruise lines.
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43 Cruises (45 Cruise Departures)
17 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

17 Days (16 Nights) Barcelona to Orlando
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Escape
Departure: 28 October 2026
Visit: Spain, France, Morocco, USA
Inside
$1,249
Oceanview
$1,549
Balcony
$2,049
Suite
$2,049
From
US$1,249
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Barcelona to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 31 October 2026
Visit: Spain, Portugal, Puerto Rico, USA
Inside
$712
Oceanview
$880
Balcony
$1,132
Suite
$2,476
From
US$712
Per Person
View Trip
48 Day Footsteps Of Columbus with Oceania Cruises
Cruise
 (1)

48 Days (47 Nights) Barcelona to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 02 November 2026
Visit: Spain, Portugal, Puerto Rico, Bahamas (+9 more), USA, Virgin Islands, Antigua and Barbuda, Saint Lucia, Trinidad and Tobago, Brazil, Barbados, Dominica, Saint Martin
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$20,049
Suite
$48,299
From
US$20,049
Save 20,049
Per Person
View Trip
15 Day Spain to Miami Halloween Transatlantic with Virgin Voyages
Cruise
 (5)

15 Days (14 Nights) Barcelona to Miami
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departure: 24 October 2027
Visit: Spain, Portugal, USA
Inside
$1,386
Oceanview
$1,469
Balcony
$1,600
Suite
$5,950
From
US$1,386
Per Person
View Trip
15 Day Spain & Bermuda Transatlantic with Celebrity Cruises
Cruise
 (2)

15 Days (14 Nights) Barcelona to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Eclipse
Departure: 10 November 2026
Visit: Spain, Gibraltar, Bermuda, USA
Exclusive Savings
Inside
$1,413
Oceanview
$1,413
Balcony
$1,537
Suite
-
From
US$1,413
Save 832
Per Person
View Trip
14 Day Barcelona To Miami with Cunard
Cruise
 (13)

14 Days (13 Nights) Barcelona to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 29 October 2027
Visit: Spain, USA
Value Fare
Inside
$2,599
Oceanview
$2,899
Balcony
$3,299
Suite
$7,849
From
US$2,599
Per Person
View Trip
16 Day Spanish Passage with Princess
Cruise
 (7)

16 Days (15 Nights) Barcelona to Fort Lauderdale
Cruise Line: Princess
Ship: Sun Princess
Departure: 31 October 2026
Visit: Spain, Gibraltar, USA
Princess Standard
Sanctuary Collection
Inside
$1,205
Oceanview
$1,325
Balcony
$1,735
Suite
$2,145
From
US$1,205
Per Person
View Trip
14 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

14 Days (13 Nights) Barcelona to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Aura
Departure: 28 May 2027
Visit: Spain, Gibraltar, USA
Inside
-
Oceanview
$2,549
Balcony
$2,949
Suite
$4,049
From
US$2,549
Per Person
View Trip
16 Day Fall Caribbean Passage with Oceania Cruises
Cruise
 (3)

16 Days (15 Nights) Barcelona to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 25 November 2026
Visit: Spain, Portugal, Puerto Rico, Dominican Republic, USA
Your World Inclusions
Exclusive Savings
Inside
$3,150
Oceanview
$3,975
Balcony
$4,012
Suite
$5,250
From
US$3,150
Save 5,248
Per Person
View Trip
23 Day Flamenco To Flamingos with Oceania Cruises
Cruise
 (1)

23 Days (22 Nights) Barcelona to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 02 November 2026
Visit: Spain, Portugal, Puerto Rico, Bahamas, USA
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$5,949
Oceanview
$6,349
Balcony
$8,699
Suite
$11,899
From
US$5,949
Save 5,949
Per Person
View Trip
13 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

13 Days (12 Nights) Barcelona to Orlando
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 31 October 2027
Visit: Spain, Portugal, USA
Inside
$1,059
Oceanview
$1,659
Balcony
$1,709
Suite
$2,009
From
US$1,059
Per Person
View Trip
14 Day Transatlantic Cruise: Malaga, San Juan & Miami with Azamara Cruises
Cruise
 (5)

14 Days (13 Nights) Malaga to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 04 December 2026
Visit: Spain, Morocco, Puerto Rico, USA
Azamara Circle Member - Quarterly Saving
Azamara Always Included
Inside
-
Oceanview
-
Balcony
$2,779
Suite
$5,519
From
US$2,779
Per Person
View Trip
14 Day Transatlantic Cruise: Malaga To Miami with Azamara Cruises
Cruise
 (8)

14 Days (13 Nights) Malaga to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 09 December 2027
Visit: Spain, Morocco, Virgin Islands, USA
Azamara Always Included
Inside
$1,809
Oceanview
$2,219
Balcony
$3,419
Suite
$5,479
From
US$1,809
Per Person
View Trip
14 Day Atlantic Ocean Passage with Viking Cruises
Cruise
 (5)

14 Days (13 Nights) Barcelona to Fort Lauderdale
Cruise Line: Viking Cruises
Ships: Viking Sky, Viking Vesta
Departures: Dec 2026 to Dec 2027
Visit: Spain, Portugal, Sint Maarten, USA
Viking $799 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,099
Suite
$5,499
From
US$3,099
Save 450
Per Person
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

14 Days (13 Nights) Barcelona to Miami
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 31 October 2026
Visit: Spain, Portugal, Puerto Rico, USA
Inside
$747
Oceanview
$815
Balcony
$1,052
Suite
-
From
US$747
Per Person
View Trip
15 Day Western Europe Passage with Princess
Cruise
 (7)

15 Days (14 Nights) Barcelona to Fort Lauderdale
Cruise Line: Princess
Ship: Sun Princess
Departure: 07 November 2027
Visit: Spain, Gibraltar, Portugal, USA
Princess Standard
Sanctuary Collection
Inside
$974
Oceanview
$1,414
Balcony
$1,994
Suite
$2,464
From
US$974
Per Person
View Trip
15 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

15 Days (14 Nights) Barcelona to Orlando
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 01 November 2026
Visit: Spain, Virgin Islands, Bahamas, USA
Inside
$959
Oceanview
-
Balcony
$1,309
Suite
$1,509
From
US$959
Per Person
View Trip
28 Day Spain And Eastern Caribbean with Cunard
Cruise
 (13)

28 Days (27 Nights) Barcelona to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 29 October 2027
Visit: Spain, USA, Virgin Islands, Saint Kitts and Nevis (+4 more), Grenada, Barbados, Saint Lucia, Saint Martin
Value Fare
Inside
$4,139
Oceanview
$4,939
Balcony
$5,989
Suite
$14,989
From
US$4,139
Per Person
View Trip
35 Day Cultural Crossing with Oceania Cruises
Cruise
 (1)

35 Days (34 Nights) Barcelona to New York
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 16 August 2027
Visit: Spain, Morocco, Gibraltar, Portugal (+8 more), France, Guernsey, England, Ireland, Northern Ireland, Iceland, Canada, USA
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$9,749
Oceanview
$10,199
Balcony
$14,749
Suite
$20,349
From
US$9,749
Save 9,749
Per Person
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

16 Days (15 Nights) Palma de Mallorca to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 30 October 2026
Visit: Spain, Portugal, Puerto Rico, USA
Inside
$836
Oceanview
$1,065
Balcony
$1,265
Suite
-
From
US$836
Per Person
View Trip
15 Day Spanish Isles & Transatlantic Miles with Virgin Voyages
Cruise
 (1)

15 Days (14 Nights) Barcelona to Miami
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 11 October 2026
Visit: Spain, Morocco, USA
Inside
$1,469
Oceanview
$1,537
Balcony
$1,806
Suite
$4,746
From
US$1,469
Per Person
View Trip
15 Day Cultural Crossing With Andalusia with Holland America
Cruise
 (3)

15 Days (14 Nights) Barcelona to Fort Lauderdale
Cruise Line: Holland America
Ship: Oosterdam
Departure: 04 November 2026
Visit: Spain, Gibraltar, Bermuda, USA
Fare Saver
Inside
$869
Oceanview
$1,019
Balcony
$1,369
Suite
$3,519
From
US$869
Per Person
View Trip
18 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

18 Days (17 Nights) Barcelona to Galveston
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 14 October 2026
Visit: Spain, Portugal, Saint Martin, Dominican Republic, Jamaica, USA
Inside
$1,629
Oceanview
$1,849
Balcony
$2,049
Suite
$3,749
From
US$1,629
Per Person
View Trip
16 Day Spain & Bermuda Transatlantic with Celebrity Cruises
Cruise
 (2)

16 Days (15 Nights) Barcelona to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Eclipse
Departure: 08 November 2027
Visit: Spain, Morocco, Bermuda, USA
Exclusive Savings
Inside
$1,073
Oceanview
$1,524
Balcony
$1,506
Suite
$6,025
From
US$1,073
Save 600
Per Person
View Trip
15 Day Atlantic Ocean Zephyr with Regent Seven Seas
Cruise

15 Days (14 Nights) Barcelona to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 05 December 2027
Visit: Spain, Morocco, Portugal, Bermuda, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,399
Suite
$10,599
From
US$9,399
Save 9,399
Per Person
View Trip
17 Day Maritime Magic To Miami with Regent Seven Seas
Cruise

17 Days (16 Nights) Barcelona to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 04 November 2027
Visit: Spain, Morocco, Puerto Rico, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,949
Suite
$14,199
From
US$13,949
Save 13,949
Per Person
View Trip
15 Day Moonlight Over Bermuda with Regent Seven Seas
Cruise

15 Days (14 Nights) Barcelona to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 26 October 2026
Visit: Spain, Portugal, Bermuda, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$11,599
From
US$11,599
Save 11,599
Per Person
View Trip
15 Day Spain & Morocco Transatlantic with Royal Caribbean
Cruise

15 Days (14 Nights) Barcelona to Fort Lauderdale
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 01 November 2027
Visit: Spain, Morocco, USA
Bonus Onboard Credit
Exclusive Savings
Inside
$981
Oceanview
$1,200
Balcony
$1,641
Suite
$3,041
From
US$981
Save 334
Per Person
View Trip
14 Day Spain Transatlantic with Royal Caribbean
Cruise

14 Days (13 Nights) Barcelona to Orlando
Cruise Line: Royal Caribbean
Ship: Harmony of the Seas
Departure: 26 July 2026
Visit: Spain, USA
Exclusive Savings
Inside
$1,545
Oceanview
$1,696
Balcony
$1,708
Suite
-
From
US$1,545
Save 780
Per Person
View Trip
17 Day A Grand Journey Of Lively Culture & Stunning Beaches with Explora Journeys
Cruise

17 Days (16 Nights) Barcelona to Miami
Cruise Line: Explora Journeys
Ships: Explora II, Explora I
Departures: Nov 2026 to Nov 2027
Visit: Spain, Portugal, Antigua and Barbuda, Anguilla, Puerto Rico, USA
Inside
-
Oceanview
-
Balcony
-
Suite
$7,280
From
US$7,280
Per Person
View Trip
Results: 1-30 of 43

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