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Cruises from Spain to USA

Are you looking for a cruise from Spain to USA? October is the most popular month to cruise between Spain and USA and there are 45 departures available from thirteen of the world's leading cruise lines.
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43 Cruises (45 Cruise Departures)
23 Day MSC Grand Voyages with MSC Cruises
Cruise

23 Days (22 Nights) Barcelona to Miami
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 20 October 2026
Visit: Spain, Gibraltar, Morocco, Portugal, USA
Inside
$1,481
Oceanview
$1,890
Balcony
$2,172
Suite
$6,015
From
US$1,481
Per Person
View Trip
15 Day Atlantic Ocean Zephyr with Regent Seven Seas
Cruise

15 Days (14 Nights) Barcelona to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 05 December 2027
Visit: Spain, Morocco, Portugal, Bermuda, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,399
Suite
$10,599
From
US$9,399
Save 9,399
Per Person
View Trip
17 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

17 Days (16 Nights) Barcelona to Orlando
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Escape
Departure: 28 October 2026
Visit: Spain, France, Morocco, USA
Inside
$1,399
Oceanview
$1,749
Balcony
$1,999
Suite
$2,299
From
US$1,399
Per Person
View Trip
16 Day Spain & Bermuda Transatlantic with Celebrity Cruises
Cruise
 (2)

16 Days (15 Nights) Barcelona to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Eclipse
Departure: 08 November 2027
Visit: Spain, Morocco, Bermuda, USA
Exclusive Savings
Inside
$1,073
Oceanview
$1,524
Balcony
$1,506
Suite
$6,025
From
US$1,073
Save 600
Per Person
View Trip
15 Day Spain & Bermuda Transatlantic with Royal Caribbean
Cruise

15 Days (14 Nights) Barcelona to New Orleans
Cruise Line: Royal Caribbean
Ship: Mariner of the Seas
Departure: 21 October 2027
Visit: Spain, Gibraltar, Bermuda, USA
Bonus Onboard Credit
Exclusive Savings
Inside
$949
Oceanview
$998
Balcony
$1,443
Suite
$2,435
From
US$949
Save 473
Per Person
View Trip
33 Day Rivieras To The Caribbean with Oceania Cruises
Cruise

33 Days (32 Nights) Barcelona to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 31 October 2026
Visit: Spain, France, Italy, Sicily (+6 more), Malta, Tunisia, Sardinia, Morocco, Puerto Rico, USA
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,649
Suite
-
From
US$14,649
Save 14,649
Per Person
View Trip
15 Day The Magnificent Atlantic with Regent Seven Seas
Cruise

15 Days (14 Nights) Barcelona to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 06 December 2027
Visit: Spain, Puerto Rico, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$11,199
From
US$11,199
Save 11,199
Per Person
View Trip
15 Day Western Europe Passage with Princess
Cruise
 (7)

15 Days (14 Nights) Barcelona to Fort Lauderdale
Cruise Line: Princess
Ship: Sun Princess
Departure: 07 November 2027
Visit: Spain, Gibraltar, Portugal, USA
Princess Standard
Sanctuary Collection
Inside
$1,049
Oceanview
$1,489
Balcony
$2,119
Suite
$2,639
From
US$1,049
Per Person
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

14 Days (13 Nights) Barcelona to Miami
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 31 October 2026
Visit: Spain, Portugal, Puerto Rico, USA
Inside
$708
Oceanview
$894
Balcony
$1,100
Suite
-
From
US$708
Per Person
View Trip
15 Day Spain & Morocco Transatlantic with Royal Caribbean
Cruise

15 Days (14 Nights) Barcelona to Fort Lauderdale
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 01 November 2027
Visit: Spain, Morocco, USA
Bonus Onboard Credit
Exclusive Savings
Inside
$848
Oceanview
$1,078
Balcony
$1,540
Suite
$2,595
From
US$848
Save 438
Per Person
View Trip
48 Day Footsteps Of Columbus with Oceania Cruises
Cruise
 (1)

48 Days (47 Nights) Barcelona to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 02 November 2026
Visit: Spain, Portugal, Puerto Rico, Bahamas (+9 more), USA, Virgin Islands, Antigua and Barbuda, Saint Lucia, Trinidad and Tobago, Brazil, Barbados, Dominica, Saint Martin
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
$14,699
Balcony
$20,049
Suite
$48,299
From
US$14,699
Save 14,699
Per Person
View Trip
14 Day Atlantic Ocean Passage with Viking Cruises
Cruise
 (5)

14 Days (13 Nights) Barcelona to Fort Lauderdale
Cruise Line: Viking Cruises
Ships: Viking Sky, Viking Vesta
Departures: Dec 2026 to Dec 2027
Visit: Spain, Portugal, Sint Maarten, USA
Viking $799 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,099
Suite
$5,499
From
US$3,099
Save 450
Per Person
View Trip
16 Day Fall Caribbean Passage with Oceania Cruises
Cruise
 (3)

16 Days (15 Nights) Barcelona to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 25 November 2026
Visit: Spain, Portugal, Puerto Rico, Dominican Republic, USA
Your World Inclusions
Exclusive Savings
Inside
$4,199
Oceanview
$5,299
Balcony
$4,012
Suite
$5,175
From
US$4,012
Save 6,686
Per Person
View Trip
14 Day Transatlantic Cruise: Malaga, San Juan & Miami with Azamara Cruises
Cruise
 (5)

14 Days (13 Nights) Malaga to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 04 December 2026
Visit: Spain, Morocco, Puerto Rico, USA
Azamara Circle Member - Quarterly Saving
Azamara Always Included
Inside
-
Oceanview
$1,749
Balcony
$2,779
Suite
$5,519
From
US$1,749
Per Person
View Trip
17 Day Spain & Bermuda Transatlantic with Celebrity Cruises
Cruise

17 Days (16 Nights) Barcelona to Miami
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departure: 23 October 2026
Visit: Spain, Gibraltar, Portugal, Bermuda, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,609
Suite
-
From
US$3,609
Save 2,240
Per Person
View Trip
15 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

15 Days (14 Nights) Barcelona to Orlando
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 01 November 2026
Visit: Spain, Virgin Islands, Bahamas, USA
Inside
$1,009
Oceanview
-
Balcony
$1,489
Suite
$1,609
From
US$1,009
Per Person
View Trip
15 Day Cultural Crossing With Andalusia with Holland America
Cruise
 (3)

15 Days (14 Nights) Barcelona to Fort Lauderdale
Cruise Line: Holland America
Ship: Oosterdam
Departure: 04 November 2026
Visit: Spain, Gibraltar, Bermuda, USA
Fare Saver
Inside
$969
Oceanview
$1,119
Balcony
$1,589
Suite
$4,019
From
US$969
Per Person
View Trip
15 Day Rose-hued Palaces & Playas with Oceania Cruises
Cruise

15 Days (14 Nights) Barcelona to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 18 November 2027
Visit: Spain, Portugal, Bermuda, USA
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,549
Suite
$7,699
From
US$5,549
Save 5,549
Per Person
View Trip
28 Day Spain And Eastern Caribbean with Cunard
Cruise
 (13)

28 Days (27 Nights) Barcelona to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 29 October 2027
Visit: Spain, USA, Virgin Islands, Saint Kitts and Nevis (+4 more), Grenada, Barbados, Saint Lucia, Saint Martin
Inside
$4,139
Oceanview
$4,939
Balcony
$5,989
Suite
$14,989
From
US$4,139
Per Person
View Trip
14 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

14 Days (13 Nights) Barcelona to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Aura
Departure: 28 May 2027
Visit: Spain, Gibraltar, USA
Inside
-
Oceanview
$2,449
Balcony
$2,849
Suite
$3,849
From
US$2,449
Per Person
View Trip
16 Day Spanish Passage with Princess
Cruise
 (7)

16 Days (15 Nights) Barcelona to Fort Lauderdale
Cruise Line: Princess
Ship: Sun Princess
Departure: 31 October 2026
Visit: Spain, Gibraltar, USA
Princess Standard
Sanctuary Collection
Inside
$1,280
Oceanview
$1,400
Balcony
$1,710
Suite
$8,185
From
US$1,280
Per Person
View Trip
15 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise

15 Days (14 Nights) Barcelona to Jacksonville
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Dawn
Departure: 05 November 2027
Visit: Spain, Morocco, Bahamas, USA
Inside
$1,159
Oceanview
$1,409
Balcony
$2,059
Suite
$2,509
From
US$1,159
Per Person
View Trip
13 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

13 Days (12 Nights) Barcelona to Orlando
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 31 October 2027
Visit: Spain, Portugal, USA
Inside
$1,059
Oceanview
$1,659
Balcony
$1,709
Suite
$2,009
From
US$1,059
Per Person
View Trip
15 Day Spain to Miami Halloween Transatlantic with Virgin Voyages
Cruise
 (5)

15 Days (14 Nights) Barcelona to Miami
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departure: 24 October 2027
Visit: Spain, Portugal, USA
Inside
$1,386
Oceanview
$1,469
Balcony
$1,600
Suite
$6,050
From
US$1,386
Per Person
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

16 Days (15 Nights) Palma de Mallorca to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 30 October 2026
Visit: Spain, Portugal, Puerto Rico, USA
Inside
$836
Oceanview
$1,065
Balcony
$1,265
Suite
$2,698
From
US$836
Per Person
View Trip
15 Day Spanish Isles & Transatlantic Miles with Virgin Voyages
Cruise
 (1)

15 Days (14 Nights) Barcelona to Miami
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 11 October 2026
Visit: Spain, Morocco, USA
Inside
$1,386
Oceanview
$1,526
Balcony
$1,666
Suite
$4,746
From
US$1,386
Per Person
View Trip
17 Day A Grand Journey Of Lively Culture & Stunning Beaches with Explora Journeys
Cruise

17 Days (16 Nights) Barcelona to Miami
Cruise Line: Explora Journeys
Ships: Explora II, Explora I
Departures: Nov 2026 to Nov 2027
Visit: Spain, Portugal, Antigua and Barbuda, Anguilla, Puerto Rico, USA
Inside
-
Oceanview
-
Balcony
-
Suite
$6,825
From
US$6,825
Per Person
View Trip
28 Day A Grand Journey Of Colourful Moroccan Shores & Idyllic Caribbean Scenery with Explora Journeys
Cruise

28 Days (27 Nights) Barcelona to Miami
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 21 October 2026
Visit: Spain, Portugal, Morocco, Antigua and Barbuda, Anguilla, Puerto Rico, USA
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$14,660
From
US$14,660
Per Person
View Trip
23 Day Flamenco To Flamingos with Oceania Cruises
Cruise
 (1)

23 Days (22 Nights) Barcelona to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 02 November 2026
Visit: Spain, Portugal, Puerto Rico, Bahamas, USA
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$5,749
Oceanview
$6,299
Balcony
$8,549
Suite
$11,799
From
US$5,749
Save 5,749
Per Person
View Trip
15 Day Cultural Crossing With Andalusia & Bermuda with Holland America
Cruise
 (3)

15 Days (14 Nights) Barcelona to Fort Lauderdale
Cruise Line: Holland America
Ship: Oosterdam
Departure: 02 November 2027
Visit: Spain, Gibraltar, Bermuda, USA
Book Early & Have It All Fare Option
Inside
$1,179
Oceanview
$1,379
Balcony
$1,609
Suite
$4,329
From
US$1,179
Per Person
View Trip
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