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Cruises from Spain to USA

Are you looking for a cruise from Spain to USA? October is the most popular month to cruise between Spain and USA and there are 41 departures available from thirteen of the world's leading cruise lines.
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48 Days
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39 Cruises (41 Cruise Departures)
25 Day A Grand Journey of Vibrant Cultures, Mayan Marvels & Idyllic Beaches with Explora Journeys
Cruise

25 Days (24 Nights) Barcelona to Miami
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 01 November 2026
Visit: Spain, Portugal, Antigua and Barbuda, Anguilla (+6 more), Puerto Rico, USA, Mexico, Honduras, Belize, Bahamas
Inside
-
Oceanview
-
Balcony
-
Suite
$10,780
From
US$10,780
Per Person
View Trip
16 Day Fall Caribbean Passage with Oceania Cruises
Cruise
 (3)

16 Days (15 Nights) Barcelona to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 25 November 2026
Visit: Spain, Portugal, Puerto Rico, Dominican Republic, USA
Your World Inclusions
Exclusive Savings
Inside
$3,622
Oceanview
$4,544
Balcony
$4,980
Suite
$6,435
From
US$3,622
Save 3,776
Per Person
View Trip
48 Day Footsteps Of Columbus with Oceania Cruises
Cruise
 (1)

48 Days (47 Nights) Barcelona to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 02 November 2026
Visit: Spain, Portugal, Puerto Rico, Bahamas (+9 more), USA, Virgin Islands, Antigua and Barbuda, Saint Lucia, Trinidad and Tobago, Brazil, Barbados, Dominica, Saint Martin
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
$13,028
Balcony
$19,479
Suite
$25,978
From
US$13,028
Save 13,570
Per Person
View Trip
25 Day Transatlantic Cruise: Barcelona To Miami with Azamara Cruises
Cruise
 (8)

25 Days (24 Nights) Barcelona to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 06 November 2027
Visit: Spain, Gibraltar, Portugal, Morocco, USA
Azamara Always Included
Exclusive Savings
Inside
$13,543
Oceanview
$15,542
Balcony
$18,684
Suite
-
From
US$13,543
Save 376
Per Person
View Trip
15 Day Spanish Isles & Transatlantic Miles with Virgin Voyages
Cruise
 (1)

15 Days (14 Nights) Barcelona to Miami
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 11 October 2026
Visit: Spain, Morocco, USA
Limited Time Offer
Inside
$1,471
Oceanview
$1,526
Balcony
$1,806
Suite
$5,026
From
US$1,471
Per Person
View Trip
15 Day Cultural Crossing With Andalusia with Holland America
Cruise
 (3)

15 Days (14 Nights) Barcelona to Fort Lauderdale
Cruise Line: Holland America
Ship: Oosterdam
Departure: 04 November 2026
Visit: Spain, Gibraltar, Bermuda, USA
Fare Saver
Inside
$1,019
Oceanview
$1,119
Balcony
$1,469
Suite
$3,949
From
US$1,019
Per Person
View Trip
15 Day Cultural Crossing With Andalusia & Bermuda with Holland America
Cruise
 (3)

15 Days (14 Nights) Barcelona to Fort Lauderdale
Cruise Line: Holland America
Ship: Oosterdam
Departure: 02 November 2027
Visit: Spain, Gibraltar, Bermuda, USA
Book Early & Have It All Fare Option
Inside
$1,179
Oceanview
$1,379
Balcony
$1,609
Suite
$4,253
From
US$1,179
Per Person
View Trip
39 Day Barcelona To Miami Grand Voyage with Azamara Cruises
Cruise
 (8)

39 Days (38 Nights) Barcelona to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 06 November 2027
Visit: Spain, Gibraltar, Portugal, Morocco (+9 more), USA, Virgin Islands, Saint Martin, Martinique, Saint Lucia, Barbados, Dominica, Saint Kitts and Nevis, Puerto Rico
Azamara Always Included
Exclusive Savings
Inside
$19,027
Oceanview
$21,374
Balcony
$24,866
Suite
-
From
US$19,027
Save 512
Per Person
View Trip
33 Day Rivieras To The Caribbean with Oceania Cruises
Cruise

33 Days (32 Nights) Barcelona to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 31 October 2026
Visit: Spain, France, Italy, Sicily (+6 more), Malta, Tunisia, Sardinia, Morocco, Puerto Rico, USA
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,145
Suite
$19,577
From
US$14,145
Save 14,853
Per Person
View Trip
14 Day Transatlantic Cruise: Malaga, San Juan & Miami with Azamara Cruises
Cruise
 (4)

14 Days (13 Nights) Malaga to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 04 December 2026
Visit: Spain, Morocco, Puerto Rico, USA
Azamara Always Included
Inside
-
Oceanview
$1,919
Balcony
$3,140
Suite
$6,235
From
US$1,919
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Barcelona to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 31 October 2026
Visit: Spain, Portugal, Puerto Rico, USA
Inside
$973
Oceanview
$1,165
Balcony
$1,394
Suite
$2,736
From
US$973
Per Person
View Trip
14 Day Barcelona To Miami with Cunard
Cruise
 (13)

14 Days (13 Nights) Barcelona to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 29 October 2027
Visit: Spain, USA
Inside
$2,599
Oceanview
$2,899
Balcony
$3,299
Suite
$7,776
From
US$2,599
Per Person
View Trip
35 Day Cultural Crossing with Oceania Cruises
Cruise
 (1)

35 Days (34 Nights) Barcelona to New York
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 16 August 2027
Visit: Spain, Morocco, Gibraltar, Portugal (+8 more), France, Guernsey, England, Ireland, Northern Ireland, Iceland, Canada, USA
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$9,549
Oceanview
$9,985
Balcony
$14,399
Suite
$19,831
From
US$9,549
Save 9,949
Per Person
View Trip
15 Day Spain & Morocco Transatlantic with Royal Caribbean
Cruise

15 Days (14 Nights) Barcelona to Fort Lauderdale
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 01 November 2027
Visit: Spain, Morocco, USA
Bonus Onboard Credit
Exclusive Savings
Inside
$978
Oceanview
$1,268
Balcony
$1,690
Suite
$2,516
From
US$978
Save 494
Per Person
View Trip
15 Day Rose-hued Palaces & Playas with Oceania Cruises
Cruise

15 Days (14 Nights) Barcelona to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 18 November 2027
Visit: Spain, Portugal, Bermuda, USA
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,930
Suite
$6,337
From
US$4,930
Save 5,168
Per Person
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

16 Days (15 Nights) Palma de Mallorca to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 30 October 2026
Visit: Spain, Portugal, Puerto Rico, USA
Inside
$1,052
Oceanview
$1,256
Balcony
$1,480
Suite
$2,915
From
US$1,052
Per Person
View Trip
28 Day Spain And Eastern Caribbean with Cunard
Cruise
 (13)

28 Days (27 Nights) Barcelona to Miami
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 29 October 2027
Visit: Spain, USA, Virgin Islands, Saint Kitts and Nevis (+4 more), Grenada, Barbados, Saint Lucia, Saint Martin
Inside
$4,139
Oceanview
$4,939
Balcony
$5,989
Suite
$14,850
From
US$4,139
Per Person
View Trip
15 Day Spain & Bermuda Transatlantic with Royal Caribbean
Cruise
 (2)

15 Days (14 Nights) Barcelona to Fort Lauderdale
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 02 November 2026
Visit: Spain, Portugal, Bermuda, USA
Exclusive Savings
Inside
$1,405
Oceanview
-
Balcony
-
Suite
-
From
US$2,002
Save 50
Per Person
View Trip
16 Day Pathway To Sunshine with Oceania Cruises
Cruise

16 Days (15 Nights) Barcelona to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 17 November 2026
Visit: Spain, Morocco, Puerto Rico, USA
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,369
Suite
-
From
US$5,369
Save 5,629
Per Person
View Trip
15 Day Spain & Bermuda Transatlantic with Celebrity Cruises
Cruise
 (2)

15 Days (14 Nights) Barcelona to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Eclipse
Departure: 10 November 2026
Visit: Spain, Gibraltar, Bermuda, USA
Bonus Onboard Credit
Exclusive Savings
Inside
$1,413
Oceanview
$1,404
Balcony
$1,417
Suite
-
From
US$1,404
Save 746
Per Person
View Trip
16 Day Spanish Passage with Princess
Cruise
 (6)

16 Days (15 Nights) Barcelona to Fort Lauderdale
Cruise Line: Princess
Ship: Sun Princess
Departure: 31 October 2026
Visit: Spain, Gibraltar, USA
Princess Standard
Sanctuary Collection
Inside
$1,141
Oceanview
$1,319
Balcony
$1,860
Suite
$2,165
From
US$1,141
Per Person
View Trip
16 Day Spain & Bermuda Transatlantic with Celebrity Cruises
Cruise
 (2)

16 Days (15 Nights) Barcelona to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Eclipse
Departure: 08 November 2027
Visit: Spain, Morocco, Bermuda, USA
Exclusive Savings
Inside
$1,066
Oceanview
$1,589
Balcony
$1,650
Suite
$5,891
From
US$1,066
Save 595
Per Person
View Trip
15 Day Western Europe Passage with Princess
Cruise
 (6)

15 Days (14 Nights) Barcelona to Fort Lauderdale
Cruise Line: Princess
Ship: Sun Princess
Departure: 07 November 2027
Visit: Spain, Gibraltar, Portugal, USA
Princess Standard
Sanctuary Collection
Inside
$1,190
Oceanview
$1,539
Balcony
$2,119
Suite
$2,589
From
US$1,190
Per Person
View Trip
23 Day Flamenco To Flamingos with Oceania Cruises
Cruise
 (1)

23 Days (22 Nights) Barcelona to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 02 November 2026
Visit: Spain, Portugal, Puerto Rico, Bahamas, USA
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$5,439
Oceanview
$5,973
Balcony
$8,398
Suite
$11,211
From
US$5,439
Save 5,659
Per Person
View Trip
14 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

14 Days (13 Nights) Barcelona to Miami
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Aura
Departure: 28 May 2027
Visit: Spain, Gibraltar, USA
Exclusive Savings
Inside
$1,847
Oceanview
$2,089
Balcony
$2,477
Suite
$3,496
From
US$1,847
Save 52
Per Person
View Trip
15 Day The Magnificent Atlantic with Regent Seven Seas
Cruise

15 Days (14 Nights) Barcelona to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 06 December 2027
Visit: Spain, Puerto Rico, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,420
Suite
$11,302
From
US$10,420
Save 10,778
Per Person
View Trip
15 Day Moonlight Over Bermuda with Regent Seven Seas
Cruise

15 Days (14 Nights) Barcelona to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 26 October 2026
Visit: Spain, Portugal, Bermuda, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,310
Suite
$11,192
From
US$10,310
Save 10,688
Per Person
View Trip
17 Day Spain & Bermuda Transatlantic with Celebrity Cruises
Cruise

17 Days (16 Nights) Barcelona to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departure: 29 October 2027
Visit: Spain, France, Morocco, Bermuda, USA
Exclusive Savings
Inside
$1,932
Oceanview
$1,974
Balcony
$2,277
Suite
$13,480
From
US$1,932
Save 1,101
Per Person
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

14 Days (13 Nights) Barcelona to Miami
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 31 October 2026
Visit: Spain, Portugal, Puerto Rico, USA
Inside
$912
Oceanview
$1,094
Balcony
$1,323
Suite
-
From
US$912
Per Person
View Trip
17 Day Spain & Bermuda Transatlantic with Celebrity Cruises
Cruise

17 Days (16 Nights) Barcelona to Miami
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departure: 23 October 2026
Visit: Spain, Gibraltar, Portugal, Bermuda, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,727
Suite
-
From
US$3,727
Save 2,406
Per Person
View Trip
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