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Uruguay Cruises

Are you looking for a cruise to Uruguay? Choose from 60 unique cruise itineraries to Uruguay, departing from Amalfi, Barcelona, Buenos Aires, Genoa, Itajai and more. February is the most popular month to cruise to Uruguay and we have over 136 departures available from twelve of the world's leading cruise lines.
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60 Cruises (136 Cruise Departures)
10 Day South America with MSC Cruises
Cruise
 (2)

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 17 February 2026
Visit: Argentina, Brazil, Uruguay
Bonus Onboard Credit
Inside
$1,879
Oceanview
$2,148
Balcony
$2,468
Suite
$3,424
From
US$1,879
Per Person
View Trip
12 Day Rhythms of the Brazilian Coastline with Scenic
New ReleaseCruise

12 Days (11 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 03 November 2027
Visit: Brazil, Uruguay, Argentina
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,583
Suite
$11,505
From
US$10,583
Save 14,307
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise

9 Days (8 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departures: Dec 2026 to Mar 2027
Visit: Argentina, Brazil, Uruguay
Bonus Onboard Credit
Inside
$919
Oceanview
$1,129
Balcony
$1,269
Suite
$1,839
From
US$919
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise
 (2)

10 Days (9 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 16 February 2026
Visit: Uruguay, Argentina, Brazil
Bonus Onboard Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,949
Suite
$3,624
From
US$2,949
Save 82
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departures: Jan 2027 to Feb 2027
Visit: Argentina, Brazil, Uruguay
Bonus Onboard Credit
Inside
$1,219
Oceanview
$1,469
Balcony
$1,599
Suite
$2,209
From
US$1,219
Per Person
View Trip
18 Day Fjords & Glaciers of Southern Chile & Patagonia with Scenic
New ReleaseCruise

18 Days (17 Nights) Buenos Aires to Buenos Aires
Cruise Line: Scenic
Ships: Scenic Eclipse I
Departures: Feb 2027 to Mar 2028
Visit: Argentina, Chile, Uruguay
Early Booking Savings
Fly Free Business Class
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,851
Suite
$29,296
From
US$12,851
Save 19,761
Per Person
View Trip
13 Day Brazil Intensive Cruise: Sao Paulo, Poto Belo & Rio De Janeiro with Azamara Cruises
Cruise
 (4)

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 16 February 2028
Visit: Argentina, Uruguay, Brazil
Azamara Always Included
Exclusive Savings
Inside
$4,149
Oceanview
$4,886
Balcony
$5,847
Suite
$8,417
From
US$4,149
Save 90
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Jan 2027
Visit: Brazil, Uruguay, Argentina
Bonus Onboard Credit
Inside
$1,104
Oceanview
$1,144
Balcony
$1,224
Suite
-
From
US$1,104
Per Person
View Trip
11 Day Brazilian Rhythms with Oceania Cruises
Cruise

11 Days (10 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 24 January 2026
Visit: Brazil, Uruguay, Argentina
Black Friday Sale + Your World Included
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,492
Suite
-
From
US$4,492
Save 4,706
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (2)

9 Days (8 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Feb 2026 to Mar 2026
Visit: Uruguay, Argentina, Brazil
Bonus Onboard Credit
Inside
$1,678
Oceanview
$1,955
Balcony
$2,258
Suite
$3,406
From
US$1,678
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise
 (1)

10 Days (9 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 28 December 2026
Visit: Brazil, Uruguay, Argentina
Bonus Onboard Credit
Exclusive Savings
Inside
$2,014
Oceanview
$2,062
Balcony
$2,159
Suite
-
From
US$2,014
Save 53
Per Person
View Trip
17 Day Patagonia & the Chilean Fjords with Scenic
New ReleaseCruise

17 Days (16 Nights) Buenos Aires to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 14 November 2027
Visit: Argentina, Uruguay, Chile
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,532
Suite
$18,879
From
US$15,532
Save 19,458
Per Person
View Trip
9 Day Argentina, Brazil & Uruguay with Celebrity Cruises
Cruise
 (1)

9 Days (8 Nights) Buenos Aires to Santos
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 14 March 2026
Visit: Argentina, Uruguay, Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$9,664
From
US$11,583
Save 4,440
Per Person
View Trip
9 Day Rhythms of the Brazilian Coastline with Scenic
New ReleaseCruise

9 Days (8 Nights) Buenos Aires to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 18 March 2026
Visit: Argentina, Uruguay, Brazil
Early Booking Savings
Exclusive Savings
From
US$23,109
Save 30,481
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise
 (2)

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Jan 2026 to Mar 2026
Visit: Argentina, Brazil, Uruguay
Bonus Onboard Credit
Drinks, WiFi & Onboard Credit
Exclusive Savings
Inside
$1,990
Oceanview
$2,362
Balcony
$2,565
Suite
$3,424
From
US$1,990
Save 163
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise
 (2)

10 Days (9 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Jan 2026 to Mar 2026
Visit: Uruguay, Argentina, Brazil
Bonus Onboard Credit
Exclusive Savings
Inside
-
Oceanview
$2,049
Balcony
$2,387
Suite
$3,624
From
US$2,049
Save 103
Per Person
View Trip
13 Day Buenos Aires to Rio De Janeiro with Silversea
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Silversea
Ship: Silver Ray
Departure: 17 February 2028
Visit: Argentina, Uruguay, Brazil
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,440
Suite
$14,470
From
US$11,440
Save 2,860
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (2)

9 Days (8 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Feb 2026 to Mar 2026
Visit: Argentina, Brazil, Uruguay
Bonus Onboard Credit
Exclusive Savings
Inside
$1,786
Oceanview
$1,958
Balcony
$2,258
Suite
$3,199
From
US$1,786
Save 52
Per Person
View Trip
13 Day Bossa Nova Reverie with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 07 March 2027
Visit: Argentina, Uruguay, Brazil
Your World Inclusions
Upgrade Your Experience
Exclusive Savings
Inside
$3,484
Oceanview
$3,727
Balcony
$5,133
Suite
$7,461
From
US$3,484
Save 3,614
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 05 January 2027
Visit: Argentina, Brazil, Uruguay
Bonus Onboard Credit
Inside
$1,309
Oceanview
$1,559
Balcony
$1,719
Suite
$2,296
From
US$1,309
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 27 December 2026
Visit: Argentina, Brazil, Uruguay
Bonus Onboard Credit
Inside
$1,699
Oceanview
$1,898
Balcony
$2,053
Suite
$2,674
From
US$1,699
Per Person
View Trip
13 Day Buenos Aires to Rio De Janeiro with Silversea
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 02 February 2026
Visit: Argentina, Uruguay, Brazil
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
$6,720
Balcony
$8,470
Suite
-
From
US$6,720
Save 2,880
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Itajai to Itajai
Cruise Line: MSC Cruises
Ship: MSC Divina
Departures: Feb 2027 to Mar 2027
Visit: Brazil, Uruguay, Argentina
Bonus Onboard Credit
Inside
$861
Oceanview
$931
Balcony
$1,061
Suite
-
From
US$861
Per Person
View Trip
12 Day Nights Of Samba & Tango with Regent Seven Seas
Cruise

12 Days (11 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 22 January 2027
Visit: Brazil, Uruguay, Argentina
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,347
Suite
$10,033
From
US$9,347
Save 15,051
Per Person
View Trip
29 Day Ultimate Antarctica & the Fjords of Southern Chile with Scenic
New ReleaseCruise

29 Days (28 Nights) Buenos Aires to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 17 February 2027
Visit: Argentina, Antarctica, Uruguay
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$70,995
Suite
$156,345
From
US$70,995
Save 2,080
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 22 February 2026
Visit: Brazil, Argentina, Uruguay
Bonus Onboard Credit
Inside
$1,034
Oceanview
$1,259
Balcony
$1,470
Suite
$2,061
From
US$1,034
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Preziosa
Departures: Jan 2026 to Mar 2027
Visit: Brazil, Uruguay, Argentina
Bonus Onboard Credit
Inside
$889
Oceanview
$959
Balcony
$1,089
Suite
$1,349
From
US$889
Per Person
View Trip
13 Day Rio De Janeiro to Buenos Aires with Silversea
Cruise

13 Days (12 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 14 February 2026
Visit: Brazil, Uruguay, Argentina
Last Minute Fare
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$6,800
Suite
$13,920
From
US$6,800
Per Person
View Trip
7 Day South America with MSC Cruises
Cruise

7 Days (6 Nights) Itajai to Santos
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 08 March 2027
Visit: Brazil, Uruguay, Argentina
Inside
$779
Oceanview
$969
Balcony
$1,069
Suite
-
From
US$779
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 10 February 2027
Visit: Argentina, Brazil, Uruguay
Bonus Onboard Credit
Inside
$1,209
Oceanview
$1,459
Balcony
$1,589
Suite
$2,199
From
US$1,209
Per Person
View Trip
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