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Uruguay Cruises Starting In December 2026 and 2027

If you're looking at joining a cruise to Uruguay in December 2026 or 2027, we have 19 unique cruise itineraries and 53 departures available, operated by six of the world's leading cruise lines departing in December.
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23 Days
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19 Cruises (53 Cruise Departures)
10 Day South America with MSC Cruises
Cruise
 (1)

10 Days (9 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 28 December 2026
Visit: Brazil, Uruguay, Argentina
Inside
$2,217
Oceanview
$2,407
Balcony
$2,627
Suite
-
From
US$2,217
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Jan 2027
Visit: Brazil, Uruguay, Argentina
Inside
$1,214
Oceanview
$1,344
Balcony
$1,654
Suite
-
From
US$1,214
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise

9 Days (8 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 31 December 2026
Visit: Brazil, Uruguay, Argentina
Inside
-
Oceanview
-
Balcony
$2,461
Suite
$3,217
From
US$2,461
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise

9 Days (8 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departures: Dec 2026 to Mar 2027
Visit: Argentina, Brazil, Uruguay
Inside
$1,249
Oceanview
$1,557
Balcony
$1,689
Suite
$2,338
From
US$1,249
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise

9 Days (8 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departures: Dec 2026 to Mar 2027
Visit: Brazil, Uruguay, Argentina
Inside
-
Oceanview
-
Balcony
$1,592
Suite
$2,240
From
US$1,592
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 27 December 2026
Visit: Argentina, Brazil, Uruguay
Inside
$2,068
Oceanview
$2,420
Balcony
$2,563
Suite
$3,300
From
US$2,068
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 22 December 2026
Visit: Brazil, Uruguay, Argentina
Inside
-
Oceanview
-
Balcony
$2,061
Suite
$2,844
From
US$2,061
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (7)

18 Days (17 Nights) Buenos Aires to Santiago
Cruise Line: Viking Cruises
Ship: Viking Jupiter
Departures: Dec 2026 to Feb 2028
Visit: Argentina, Uruguay, Falkland Islands, Chile
Viking $1,799 Air Deal
Inside
-
Oceanview
-
Balcony
$8,299
Suite
$12,999
From
US$8,299
Per Person
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (7)

18 Days (17 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Jupiter
Departures: Dec 2026 to Feb 2028
Visit: Chile, Argentina, Falkland Islands, Uruguay
Viking $1,799 Air Deal
Inside
-
Oceanview
-
Balcony
$8,299
Suite
$12,999
From
US$8,299
Per Person
View Trip
15 Day Patagonia & Argentina Cruise with Celebrity Cruises
Cruise
 (1)

15 Days (14 Nights) Buenos Aires to Buenos Aires
Cruise Line: Celebrity Cruises
Ships: Celebrity Equinox
Departures: Dec 2026 to Feb 2028
Visit: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Inside
$2,283
Oceanview
$2,520
Balcony
$2,599
Suite
$6,713
From
US$2,283
Save 2,177
Per Person
View Trip
16 Day Cape Horn & Glaciers of Patagonia with Princess
Cruise
 (8)

16 Days (15 Nights) Buenos Aires to Santiago
Cruise Line: Princess
Ship: Majestic Princess
Departures: Dec 2026 to Nov 2027
Visit: Argentina, Uruguay, Falkland Islands, Chile
Princess Standard
Inside
$2,172
Oceanview
-
Balcony
$2,301
Suite
$2,772
From
US$2,172
Per Person
View Trip
15 Day Patagonia & Argentina Holiday with Celebrity Cruises
Cruise
 (1)

15 Days (14 Nights) Buenos Aires to Buenos Aires
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 19 December 2027
Visit: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
Inside
$2,565
Oceanview
$2,899
Balcony
$3,300
Suite
$11,016
From
US$2,565
Save 1,332
Per Person
View Trip
16 Day South America Pathways: Chilean Fjords & Glaciers with Holland America
Cruise
 (3)

16 Days (15 Nights) Santiago to Buenos Aires
Cruise Line: Holland America
Ships: Nieuw Amsterdam, Oosterdam
Departures: Dec 2026 to Dec 2027
Visit: Chile, Argentina, Falkland Islands, Uruguay
Fare Saver
Book Early & Have It All Fare Option
Inside
$2,124
Oceanview
$2,324
Balcony
$3,224
Suite
$4,599
From
US$2,124
Per Person
View Trip
16 Day Cape Horn & Glaciers of Patagonia with Princess
Cruise
 (8)

16 Days (15 Nights) Santiago to Buenos Aires
Cruise Line: Princess
Ship: Majestic Princess
Departures: Dec 2026 to Dec 2027
Visit: Chile, Argentina, Falkland Islands, Uruguay
Princess Standard
Inside
$2,102
Oceanview
-
Balcony
$2,370
Suite
$3,002
From
US$2,102
Per Person
View Trip
23 Day South America & Antarctica Holiday with Holland America
Cruise
 (3)

23 Days (22 Nights) Buenos Aires to San Antonio
Cruise Line: Holland America
Ship: Oosterdam
Departure: 19 December 2026
Visit: Argentina, Uruguay, Falkland Islands, Antarctica, Chile
Fare Saver
Inside
$5,099
Oceanview
$5,199
Balcony
$6,899
Suite
$8,799
From
US$5,099
Per Person
View Trip
16 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

16 Days (15 Nights) Lisbon to Buenos Aires
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Star
Departure: 02 December 2027
Visit: Portugal, Cape Verde, Brazil, Uruguay, Argentina
Inside
$1,629
Oceanview
$1,799
Balcony
$2,579
Suite
$2,899
From
US$1,629
Per Person
View Trip
17 Day South America & Antarctica From Buenos Aires To Santiago with Norwegian Cruise Line
Cruise
 (1)

17 Days (16 Nights) Buenos Aires to Santiago
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Star
Departure: 17 December 2027
Visit: Argentina, Uruguay, Falkland Islands, Antarctica, Chile
Inside
$3,789
Oceanview
$4,289
Balcony
$6,079
Suite
$6,519
From
US$3,789
Per Person
View Trip
23 Day South America & Antarctica with Holland America
Cruise
 (3)

23 Days (22 Nights) Buenos Aires to Santiago
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departures: Dec 2027 to Jan 2028
Visit: Argentina, Uruguay, Falkland Islands, Antarctica, Chile
Book Early & Have It All Fare Option
Inside
$4,569
Oceanview
$4,969
Balcony
$6,569
Suite
$8,769
From
US$4,569
Per Person
View Trip
18 Day Antarctica & South America with Princess
Cruise
 (8)

18 Days (17 Nights) Buenos Aires to Buenos Aires
Cruise Line: Princess
Ship: Majestic Princess
Departures: Dec 2027 to Jan 2028
Visit: Argentina, Chile, Antarctica, Falkland Islands, Uruguay
Princess Standard
Inside
$2,949
Oceanview
-
Balcony
$3,796
Suite
$4,849
From
US$2,949
Per Person
View Trip
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