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USA Luxury Cruises

Explore the best luxury cruises up and down the east and west coasts of the US. Choose from 45 unique cruise itineraries from 7 leading cruise lines. September is the most popular month to join a luxury cruise up and down the east and west coasts of the US with 58 departures starting between April 2023 and May 2025.
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45 Cruises (58 Cruise Departures)
6 Day Pacific Coastal with Cunard
Cruise
 (1)

6 Days (5 Nights) Vancouver to Los Angeles
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 17 August 2023
Countries Visited: Canada, USA
Inside
$1,436
Oceanview
$1,585
Balcony
$1,832
Suite
$5,644
From 1,436
View Trip
8 Day West Coast Vines with Oceania Cruises
Cruise

8 Days (7 Nights) Los Angeles to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Regatta
Departures: May 2023 to May 2023
Countries Visited: USA, Mexico
Mutiple Deals Available
Inside
$2,814
Oceanview
$3,339
Balcony
$4,319
Suite
$9,329
From 2,814
View Trip
12 Day Cruising the Great Lakes: Chicago to Toronto with Tauck
Cruise

12 Days (11 Nights) Chicago to Toronto
Operated By: Tauck
Departures: Sep 2023 to Sep 2023
Trip Style: Cruise
Countries Visited: USA, Canada
Exclusive Savings
Save 267
From 13,103
View Trip
8 Day Great Lakes of North America with Ponant
Cruise

8 Days (7 Nights) Milwaukee to Toronto
Cruise Line: Ponant
Ship: Le Champlain
Departure: 11 October 2024
Countries Visited: USA, Canada
Early Booking Bonus
Inside
-
Oceanview
-
Balcony
$9,054
Suite
$14,459
From 9,054
View Trip
4 Day Pacific Coastal with Cunard
Cruise
 (1)

4 Days (3 Nights) Vancouver to San Francisco
Cruise Line: Cunard
Ship: Queen Elizabeth
Departures: Aug 2023 to Sep 2024
Countries Visited: Canada, USA
Inside
$891
Oceanview
$990
Balcony
$1,139
Suite
$3,515
From 891
View Trip
7 Day Vancouver to San Francisco with Silversea
Cruise

7 Days (6 Nights) Vancouver to San Francisco
Cruise Line: Silversea
Ship: Silver Wind
Departure: 02 October 2023
Countries Visited: Canada, USA
Inside
-
Oceanview
$5,841
Balcony
$6,831
Suite
-
From 5,841
View Trip
9 Day Pacific Gold Coast with Seabourn
Cruise
 (1)

9 Days (8 Nights) Vancouver to Los Angeles
Cruise Line: Seabourn
Ship: Odyssey
Departure: 13 October 2023
Countries Visited: Canada, USA
Earlybird Saving
Inside
-
Oceanview
$5,659
Balcony
$6,451
Suite
$10,906
From 5,659
View Trip
8 Day West Coast Vines with Oceania Cruises
Cruise

8 Days (7 Nights) Los Angeles to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Regatta
Departure: 26 September 2024
Countries Visited: USA, Mexico
Early Booking Savings
Inside
$2,815
Oceanview
$3,339
Balcony
$4,468
Suite
$5,577
From 2,815
View Trip
11 Day Expedition in the Heart of the American Great Lakes with Ponant
Cruise

11 Days (10 Nights) Milwaukee to Toronto
Cruise Line: Ponant
Ship: Le Champlain
Departure: 24 September 2024
Countries Visited: USA, Canada
Early Booking Bonus
Inside
-
Oceanview
-
Balcony
$11,788
Suite
$20,193
From 11,788
View Trip
10 Day Iconic West Coast Experience with Scenic
Cruise

10 Days (9 Nights) San Diego to Vancouver
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 03 May 2023
Countries Visited: USA, Canada
Earlybird Saving + Early Payment Discount
Inside
-
Oceanview
-
Balcony
$14,244
Suite
$19,011
Save 1,376
From 14,244
View Trip
8 Day A Voyage along the Great Lakes - With Smithsonian Journeys with Ponant
Cruise

8 Days (7 Nights) Toronto to Milwaukee
Cruise Line: Ponant
Ships: Le Bellot, Le Champlain (+1 more), Le Dumont d’Urville
Departures: Aug 2023 to Aug 2024
Countries Visited: Canada, USA
Early Booking Bonus
Inside
-
Oceanview
-
Balcony
$9,588
Suite
$14,231
From 9,588
View Trip
12 Day Cruising the Great Lakes: Toronto to Chicago with Tauck
Cruise

12 Days (11 Nights) Toronto to Chicago
Operated By: Tauck
Departures: Sep 2023 to Sep 2023
Trip Style: Cruise
Countries Visited: Canada, USA
Exclusive Savings
Save 267
From 13,103
View Trip
8 Day Great Lakes of North America with Ponant
Cruise

8 Days (7 Nights) Milwaukee to Toronto
Cruise Line: Ponant
Ships: Le Bellot, Le Dumont d’Urville
Departures: Sep 2023 to Oct 2024
Countries Visited: USA, Canada
Early Booking Bonus
Inside
-
Oceanview
-
Balcony
$7,598
Suite
$12,063
From 7,598
View Trip
21 Day Alaska & California Treasures with Oceania Cruises
Cruise

21 Days (20 Nights) Vancouver to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Regatta
Departure: 07 September 2023
Countries Visited: Canada, USA, Mexico
Early Booking Savings
Inside
$7,317
Oceanview
$7,921
Balcony
$11,366
Suite
$16,504
From 7,317
View Trip
17 Day Vancouver to Puerto Vallarta with Silversea
Cruise

17 Days (16 Nights) Vancouver to Puerto Vallarta
Cruise Line: Silversea
Ship: Silver Wind
Departure: 02 October 2023
Countries Visited: Mexico, USA
Door-to-Door Economy Class IncludedPort-to-Port Only
Inside
-
Oceanview
$8,068
Balcony
$9,256
Suite
$18,612
From 8,068
View Trip
8 Day California Reflections with Oceania Cruises
Cruise

8 Days (7 Nights) Los Angeles to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Regatta
Departure: 20 September 2023
Countries Visited: USA, Mexico
Early Booking SavingsPast Guest Special
Inside
$2,735
Oceanview
$3,042
Balcony
$4,012
Suite
$5,428
From 2,735
View Trip
13 Day Glitz To Glaciers with Oceania Cruises
Cruise

13 Days (12 Nights) Los Angeles to Vancouver
Cruise Line: Oceania Cruises
Ship: Oceania Regatta
Departure: 18 May 2023
Countries Visited: USA, Canada
Mutiple Deals Available
Inside
$4,948
Oceanview
$5,769
Balcony
$7,947
Suite
-
From 4,948
View Trip
13 Day Gold Rush Trails with Oceania Cruises
Cruise

13 Days (12 Nights) Los Angeles to Vancouver
Cruise Line: Oceania Cruises
Ship: Oceania Regatta
Departure: 01 May 2024
Countries Visited: USA, Canada
Early Booking Savings
Inside
$5,236
Oceanview
$5,988
Balcony
$8,087
Suite
$11,047
From 5,236
View Trip
14 Day Alaska To California Medley with Oceania Cruises
Cruise

14 Days (13 Nights) Vancouver to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Regatta
Departure: 07 September 2023
Countries Visited: Canada, USA
Early Booking SavingsOLife Ultimate Offer
Inside
$4,978
Oceanview
$5,503
Balcony
$8,285
Suite
$11,849
From 4,978
View Trip
20 Day Glaciers To Sunny Shores with Oceania Cruises
Cruise

20 Days (19 Nights) Vancouver to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Regatta
Departure: 14 September 2024
Countries Visited: Canada, USA, Mexico
Early Booking Savings
Inside
$7,129
Oceanview
$8,178
Balcony
$11,782
Suite
$16,158
From 7,129
View Trip
19 Day Ultimate Majestic Coastlines of Baja California & West Coast with Scenic
Cruise

19 Days (18 Nights) Los Angeles to Vancouver
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 24 April 2023
Countries Visited: USA, Mexico, Canada
Earlybird Saving + Early Payment Discount
Inside
-
Oceanview
-
Balcony
$28,275
Suite
$37,809
Save 2,840
From 28,275
View Trip
8 Day West Coast Wonders with Oceania Cruises
Cruise

8 Days (7 Nights) Los Angeles to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Regatta
Departure: 27 September 2023
Countries Visited: USA, Mexico
Early Booking SavingsPast Guest Special
Inside
$2,517
Oceanview
$3,042
Balcony
$4,012
Suite
-
From 2,517
View Trip
25 Day Jewels Of The Atlantic with Oceania Cruises
Cruise

25 Days (24 Nights) Miami to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 19 April 2025
Countries Visited: USA, Bahamas, Bermuda, Portugal
Early Booking Savings
Inside
-
Oceanview
-
Balcony
$10,901
Suite
$16,970
From 10,901
View Trip
24 Day Across The North Pacific with Regent Seven Seas
Cruise

24 Days (23 Nights) Tokyo to San Francisco
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 14 May 2025
Countries Visited: Japan, USA, Canada
Early Booking Savings
Inside
-
Oceanview
-
Balcony
$28,102
Suite
$30,468
From 28,102
View Trip
24 Day Aleutian Bridgeway with Oceania Cruises
Cruise

24 Days (23 Nights) Tokyo to San Francisco
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 20 June 2023
Countries Visited: Japan, USA, Canada
Early Booking Savings
Inside
$9,291
Oceanview
-
Balcony
-
Suite
-
From 9,291
View Trip
27 Day North Pacific Panorama with Oceania Cruises
Cruise

27 Days (26 Nights) Los Angeles to Tokyo
Cruise Line: Oceania Cruises
Ship: Oceania Regatta
Departure: 03 October 2024
Countries Visited: USA, Canada, Japan
Early Booking Savings
Inside
$9,121
Oceanview
$10,250
Balcony
$13,626
Suite
$20,447
From 9,121
View Trip
24 Day West Coast Wilderness with Oceania Cruises
Cruise

24 Days (23 Nights) Los Angeles to Vancouver
Cruise Line: Oceania Cruises
Ship: Oceania Regatta
Departure: 20 April 2024
Countries Visited: USA, Mexico, Canada
Early Booking Savings
Inside
$8,952
Oceanview
$9,853
Balcony
$13,298
Suite
$18,159
From 8,952
View Trip
12 Day Colonial America & Bermuda with Oceania Cruises
Cruise

12 Days (11 Nights) Miami to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 16 March 2024
Countries Visited: USA, Bahamas, Bermuda
Early Booking Savings
Inside
-
Oceanview
-
Balcony
$5,805
Suite
$9,211
From 5,805
View Trip
12 Day Beacons Of Light with Regent Seven Seas
Cruise

12 Days (11 Nights) Montreal to New York
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 20 October 2023
Countries Visited: Canada, USA
Upgrade Your HorizonEarly Booking Savings
Inside
-
Oceanview
-
Balcony
$15,774
Suite
$16,329
From 15,774
View Trip
16 Day Spring In Nova Scotia with Regent Seven Seas
Cruise

16 Days (15 Nights) Miami to Montreal
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 05 May 2023
Countries Visited: USA, Bahamas, Bermuda, Canada
Early Booking Savings
Inside
-
Oceanview
$11,889
Balcony
$13,701
Suite
$15,374
From 11,889
View Trip
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