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3 Week USA Cruises

Looking to discover the best of USA on a 3 week cruise? Then choose from our range of unique cruise itineraries with seven leading cruise lines that explore USA. September is the most popular month to travel to USA and we have 23 cruise departures available.
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12 Cruises (23 Cruise Departures)
21 Day Great Canadian Rail Journey with Alaska Cruise with Globus
Tour + Cruise
 (14)

21 Days Toronto to Vancouver
Operated By: Globus
Departures: May 2026 to Aug 2027
Trip Styles: Coach, Cruise, Rail, Scenic
Visit: Canada, USA
Exclusive Savings
From
US$9,499
Save 909
Per Person
View Trip
21 Day Hawaii & Japan Pacific Crossing with Princess
Cruise

21 Days (20 Nights) Los Angeles to Tokyo
Cruise Line: Princess
Ship: Sapphire Princess
Departure: 22 November 2026
Visit: USA, Japan
Princess Standard
Inside
$1,799
Oceanview
$1,629
Balcony
$2,459
Suite
$2,719
From
US$1,629
Per Person
View Trip
21 Day Pacific Passage Adventure with Regent Seven Seas
Cruise

21 Days (20 Nights) Seattle to Tokyo
Cruise Line: Regent Seven Seas
Ship: Seven Seas Explorer
Departure: 30 September 2026
Visit: USA, Japan
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,106
Suite
$16,694
From
US$16,106
Save 16,692
Per Person
View Trip
21 Day Western Canada with Inside Passage & Alaska Cruise with Cosmos
Tour + Cruise

21 Days Calgary to Vancouver
Operated By: Cosmos
Departures: Jul 2026 to Sep 2026
Trip Styles: Coach, Cruise, Rail, Scenic
Visit: Canada, USA
Exclusive Savings
From
US$4,858
Save 325
Per Person
View Trip
21 Day Ultimate Alaska Solstice with Glacier Bay National Park with Princess
Cruise

21 Days (20 Nights) San Francisco to San Francisco
Cruise Line: Princess
Ship: Ruby Princess
Departure: 12 June 2026
Visit: USA, Canada
Princess Standard
Inside
$1,849
Oceanview
$1,963
Balcony
$3,099
Suite
$6,493
From
US$1,849
Per Person
View Trip
21 Day Pacific Frontier Escape with Regent Seven Seas
Cruise

21 Days (20 Nights) Tokyo to San Francisco
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 27 April 2028
Visit: Japan, USA, Canada
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$22,082
From
US$22,082
Save 22,916
Per Person
View Trip
21 Day Hawaii, Tahiti & South Pacific Crossing with Princess
Cruise
 (5)

21 Days (20 Nights) Auckland to Los Angeles
Cruise Line: Princess
Ship: Discovery Princess
Departure: 12 April 2026
Visit: New Zealand, French Polynesia, USA
Princess Standard
Inside
$1,472
Oceanview
-
Balcony
$1,930
Suite
-
From
US$1,472
Per Person
View Trip
21 Day Tahiti, Hawaii & South Pacific Crossing with Princess
Cruise
 (12)

21 Days (20 Nights) Auckland to Los Angeles
Cruise Line: Princess
Ship: Royal Princess
Departure: 02 April 2027
Visit: New Zealand, French Polynesia, USA
Princess Standard
Inside
$2,645
Oceanview
-
Balcony
$3,036
Suite
$4,404
From
US$2,645
Per Person
View Trip
21 Day Japan, Alaska & Pacific Crossing with Seabourn
Cruise

21 Days (20 Nights) Tokyo to Vancouver
Cruise Line: Seabourn
Ship: Seabourn Encore
Departure: 24 April 2027
Visit: Japan, USA, Canada
Weekend Sail
Yours to Explore
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,843
Suite
$19,643
From
US$9,843
Save 156
Per Person
View Trip
21 Day Los Angeles To Sydney with Cunard
Cruise

21 Days (20 Nights) Los Angeles to Sydney
Cruise Line: Cunard
Ship: Queen Anne
Departure: 07 February 2028
Visit: USA, Fiji, Australia
Inside
$3,859
Oceanview
$4,959
Balcony
$6,056
Suite
$12,342
From
US$3,859
Per Person
View Trip
21 Day Panama Canal - Ocean to Ocean with Princess
Cruise

21 Days (20 Nights) Fort Lauderdale to Seattle
Cruise Line: Princess
Ship: Star Princess
Departure: 13 April 2026
Visit: USA, Aruba, Panama, Mexico
Princess Standard
Princess Premier
Inside
$1,799
Oceanview
$2,259
Balcony
$2,299
Suite
$2,399
From
US$1,799
Per Person
View Trip
21 Day A Grand Journey Through Icelandic Fjords, Greenlandic Traditions & North American Gems with Explora Journeys
Cruise

21 Days (20 Nights) Reykjavik to New York
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 17 September 2026
Visit: Iceland, Greenland, Canada, USA
Inside
-
Oceanview
-
Balcony
-
Suite
$14,435
From
US$14,435
Per Person
View Trip
Results: 12 results

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North American Cruises

USA Cruises Canada & New England Cruises Alaska Cruises Hawaii Cruises

Travel Styles

Festivals & Events Cruises Luxury Cruises Music Themed Cruises Rail Cruises Short Break Cruises

Trip Lengths

1 Month 10 Day 2 Week 3 Day 3 Week 4 Week 7 Day

Departure Months

April May June July August September November February

Cities

Amsterdam Anchorage Baltimore Boston Cape Liberty Fort Lauderdale Galveston Honolulu Jacksonville Los Angeles Miami New Orleans New York Orlando Philadelphia San Diego San Francisco San Juan Seattle Seward Tampa Vancouver

Routes

Anchorage to Vancouver Baltimore to Baltimore Barcelona to Fort Lauderdale Barcelona to Miami Boston to Montreal Boston to Quebec City Boston to Boston Bridgetown to Miami Cape Liberty to Cape Liberty Fort Lauderdale to Los Angeles Fort Lauderdale to London Fort Lauderdale to Barcelona Fort Lauderdale to Fort Lauderdale Fort Lauderdale to San Diego Fort Lauderdale to Vancouver Galveston to Galveston Honolulu to Tahiti Honolulu to Vancouver Jacksonville to Jacksonville London to Fort Lauderdale London to New York Los Angeles to Miami Los Angeles to Vancouver Los Angeles to Los Angeles Miami to San Juan Miami to Lisbon Miami to Los Angeles Miami to Rome Miami to Bridgetown Miami to Panama City Miami to Barcelona Miami to Miami Miami to London Montreal to Boston Montreal to Miami Montreal to New York New Orleans to New Orleans New York to Montreal New York to New York New York to London Orlando to Orlando Panama City to Miami Philadelphia to Philadelphia Quebec City to Boston Rome to Fort Lauderdale Rotterdam to Fort Lauderdale San Diego to Fort Lauderdale San Diego to Vancouver San Diego to San Diego San Francisco to San Francisco San Juan to Miami Seattle to Vancouver Seattle to Seattle Seward to Vancouver Sydney to Honolulu Tahiti to Honolulu Tampa to Tampa Toronto to Boston Vancouver to Los Angeles Vancouver to Honolulu Vancouver to Seward Vancouver to Seattle Vancouver to Anchorage Vancouver to San Diego

Country Routes

Argentina to USA Australia to USA Barbados to USA Canada to USA Chile to USA Dominican Republic to USA England to USA French Polynesia to USA Greece to USA Holland to USA Iceland to USA Italy to USA Japan to USA New Zealand to USA Panama to USA Peru to USA Portugal to USA Puerto Rico to USA Spain to USA USA to Portugal USA to Germany USA to Iceland USA to Puerto Rico USA to Brazil USA to Dominican Republic USA to Argentina USA to Australia USA to Barbados USA to Canada USA to Chile USA to England USA to French Polynesia USA to Holland USA to Italy USA to Japan USA to Panama USA to Peru USA to Spain

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