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3 Week USA Cruises

Looking to discover the best of USA on a 3 week cruise? Then choose from our range of unique cruise itineraries with eight leading cruise lines that explore USA. April and September are the most popular months to travel to USA and we have 22 cruise departures available.
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14 Cruises (22 Cruise Departures)
21 Day Great Canadian Rail Journey with Alaska Cruise with Globus
Tour + Cruise
 (14)

21 Days Toronto to Vancouver
Operated By: Globus
Departures: May 2026 to Aug 2026
Trip Styles: Coach, Cruise, Rail, Scenic
Visit: Canada, USA
Black Friday Sale
Exclusive Savings
From
US$9,363
Save 859
Per Person
View Trip
21 Day Ultimate Alaska Solstice with Glacier Bay National Park with Princess
Cruise

21 Days (20 Nights) San Francisco to San Francisco
Cruise Line: Princess
Ship: Ruby Princess
Departure: 12 June 2026
Visit: USA, Canada
Princess Standard
Inside
$2,424
Oceanview
$2,980
Balcony
$4,807
Suite
$8,458
From
US$2,424
Per Person
View Trip
21 Day Hawaii & Japan Pacific Crossing with Princess
Cruise

21 Days (20 Nights) Los Angeles to Tokyo
Cruise Line: Princess
Ship: Sapphire Princess
Departure: 22 November 2026
Visit: USA, Japan
Princess Standard
Inside
$1,470
Oceanview
$1,818
Balcony
$2,446
Suite
$2,509
From
US$1,470
Per Person
View Trip
21 Day Pacific Passage Adventure with Regent Seven Seas
Cruise

21 Days (20 Nights) Seattle to Tokyo
Cruise Line: Regent Seven Seas
Ship: Seven Seas Explorer
Departure: 30 September 2026
Visit: USA, Japan
Black Friday Bonus
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,794
Suite
$11,892
From
US$11,794
Save 20,604
Per Person
View Trip
21 Day Western Canada with Inside Passage & Alaska Cruise with Cosmos
Tour + Cruise

21 Days Calgary to Vancouver
Operated By: Cosmos
Departures: Jun 2026 to Sep 2026
Trip Styles: Coach, Cruise, Rail, Scenic
Visit: Canada, USA
Black Friday Sale
Exclusive Savings
From
US$4,906
Save 277
Per Person
View Trip
21 Day Hawaii, Tahiti & South Pacific Crossing with Princess
Cruise
 (1)

21 Days (20 Nights) Auckland to Los Angeles
Cruise Line: Princess
Ship: Discovery Princess
Departure: 12 April 2026
Visit: New Zealand, French Polynesia, USA
Princess Standard
Inside
$3,097
Oceanview
$3,344
Balcony
$3,248
Suite
$3,810
From
US$3,097
Per Person
View Trip
21 Day Tahiti, Hawaii & South Pacific Crossing with Princess
Cruise
 (12)

21 Days (20 Nights) Auckland to Los Angeles
Cruise Line: Princess
Ship: Royal Princess
Departure: 02 April 2027
Visit: New Zealand, French Polynesia, USA
Princess Standard
Inside
$2,425
Oceanview
-
Balcony
$3,251
Suite
$4,587
From
US$2,425
Per Person
View Trip
21 Day Los Angeles To Sydney with Cunard
Cruise

21 Days (20 Nights) Los Angeles to Sydney
Cruise Line: Cunard
Ship: Queen Anne
Departure: 07 February 2028
Visit: USA, Fiji, Australia
Inside
$3,859
Oceanview
$4,959
Balcony
$6,056
Suite
$12,343
From
US$3,859
Per Person
View Trip
21 Day Japan, Alaska & Pacific Crossing with Seabourn
Cruise

21 Days (20 Nights) Tokyo to Vancouver
Cruise Line: Seabourn
Ship: Seabourn Encore
Departure: 24 April 2027
Visit: Japan, USA, Canada
Explore More
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,373
Suite
$15,037
From
US$8,373
Save 126
Per Person
View Trip
21 Day Pacific Frontier Escape with Regent Seven Seas
Cruise

21 Days (20 Nights) Tokyo to San Francisco
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 27 April 2028
Visit: Japan, USA, Canada
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,104
Suite
$17,133
From
US$16,104
Save 25,694
Per Person
View Trip
21 Day A Grand Journey Through Icelandic Fjords, Greenlandic Traditions & North American Gems with Explora Journeys
Cruise

21 Days (20 Nights) Reykjavik to New York
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 17 September 2026
Visit: Iceland, Greenland, Canada, USA
The Exclusive Invitation Offer
Inside
-
Oceanview
-
Balcony
$18,185
Suite
$21,160
From
US$18,185
Per Person
View Trip
21 Day Panama Canal - Ocean to Ocean with Princess
Cruise

21 Days (20 Nights) Fort Lauderdale to Seattle
Cruise Line: Princess
Ship: Star Princess
Departure: 13 April 2026
Visit: USA, Aruba, Panama, Mexico
Princess Standard
Sanctuary Collection
Inside
$1,524
Oceanview
$2,124
Balcony
$2,574
Suite
$4,042
From
US$1,524
Per Person
View Trip
21 Day Miami To Seattle with Cunard
Cruise
 (13)

21 Days (20 Nights) Miami to Seattle
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 14 April 2026
Visit: USA, Colombia, Panama, Costa Rica, Mexico
Inside
$1,589
Oceanview
$1,699
Balcony
$1,999
Suite
$6,535
From
US$1,589
Per Person
View Trip
21 Day Seattle to Miami with Silversea
Cruise
 (1)

21 Days (20 Nights) Seattle to Miami
Cruise Line: Silversea
Ship: Silver Nova
Departure: 11 May 2026
Visit: USA, Mexico, Costa Rica, Panama, Colombia
Last Minute Fare
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$7,800
Suite
$19,400
From
US$7,800
Per Person
View Trip
Results: 14 results

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North American Cruises

USA Cruises Canada & New England Cruises Alaska Cruises Hawaii Cruises

Travel Styles

Festivals & Events Cruises Luxury Cruises Music Themed Cruises Rail Cruises Short Break Cruises

Trip Lengths

1 Month 10 Day 2 Week 3 Day 3 Week 7 Day

Departure Months

April May June July August September November February

Cities

Amsterdam Anchorage Baltimore Boston Cape Liberty Fort Lauderdale Galveston Honolulu Jacksonville Los Angeles Miami New Orleans New York Orlando Philadelphia San Diego San Francisco Seattle Seward Tampa Vancouver

Routes

Anchorage to Vancouver Baltimore to Baltimore Barcelona to Fort Lauderdale Barcelona to Miami Boston to Montreal Boston to Quebec City Boston to Boston Bridgetown to Miami Cape Liberty to Cape Liberty Fort Lauderdale to Los Angeles Fort Lauderdale to Barcelona Fort Lauderdale to Fort Lauderdale Fort Lauderdale to San Diego Fort Lauderdale to Vancouver Galveston to Galveston Honolulu to Tahiti Honolulu to Vancouver Jacksonville to Jacksonville London to Fort Lauderdale London to New York Los Angeles to Miami Los Angeles to Vancouver Los Angeles to Los Angeles Miami to San Juan Miami to Lisbon Miami to Los Angeles Miami to Rome Miami to Bridgetown Miami to Panama City Miami to Barcelona Miami to Miami Miami to London Montreal to Boston Montreal to Miami Montreal to New York New Orleans to New Orleans New York to Montreal New York to New York New York to London Orlando to Orlando Panama City to Miami Philadelphia to Philadelphia Quebec City to Boston Rome to Miami Rome to Fort Lauderdale Rotterdam to Fort Lauderdale San Diego to Fort Lauderdale San Diego to Vancouver San Diego to San Diego San Francisco to San Francisco San Juan to Miami Seattle to Vancouver Seattle to Seattle Seward to Vancouver Sydney to Honolulu Tahiti to Honolulu Tampa to Tampa Vancouver to Los Angeles Vancouver to Honolulu Vancouver to Seward Vancouver to Seattle Vancouver to Anchorage Vancouver to San Diego

Country Routes

Argentina to USA Australia to USA Barbados to USA Canada to USA Chile to USA Dominican Republic to USA England to USA France to USA French Polynesia to USA Greece to USA Holland to USA Iceland to USA Italy to USA Japan to USA New Zealand to USA Panama to USA Peru to USA Portugal to USA Puerto Rico to USA Spain to USA USA to Portugal USA to Germany USA to Iceland USA to Puerto Rico USA to Brazil USA to Dominican Republic USA to Australia USA to Barbados USA to Canada USA to Chile USA to England USA to French Polynesia USA to Holland USA to Italy USA to Japan USA to Panama USA to Peru USA to Spain

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