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Cruises from Puerto Rico to USA

Are you looking for a cruise from Puerto Rico to USA? March, November and December are the most popular months to cruise between Puerto Rico and USA and there are 71 departures available from nine of the world's leading cruise lines.
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69 Cruises (71 Cruise Departures)
8 Day A Journey From San Juan To Miami with Explora Journeys
Cruise

8 Days (7 Nights) San Juan to Miami
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 06 January 2026
Visit: Puerto Rico, Saint Barthelemy, Antigua and Barbuda, Virgin Islands, Anguilla, USA
Inside
-
Oceanview
-
Balcony
$4,100
Suite
$4,750
From
US$4,100
Per Person
View Trip
17 Day An Extended Journey of Caribbean Celebrations & Tropical Idylls with Explora Journeys
Cruise

17 Days (16 Nights) San Juan to San Juan
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 28 December 2026
Visit: Puerto Rico, Antigua and Barbuda, Guadeloupe, Virgin Islands (+4 more), Dominican Republic, USA, Saint Barthelemy, Saint Kitts and Nevis
Inside
-
Oceanview
-
Balcony
$10,310
Suite
$12,560
From
US$10,310
Per Person
View Trip
8 Day A Journey Of Caribbean Delicacies & Idyllic Islands with Explora Journeys
Cruise

8 Days (7 Nights) San Juan to Miami
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 04 January 2027
Visit: Puerto Rico, Saint Martin, Antigua and Barbuda, Montserrat, Virgin Islands, USA
Inside
-
Oceanview
-
Balcony
$4,050
Suite
$4,650
From
US$4,050
Per Person
View Trip
19 Day Eastern Caribbean Voyage with Azamara Cruises
Cruise
 (3)

19 Days (18 Nights) San Juan to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 19 December 2025
Visit: Puerto Rico, Virgin Islands, Antigua and Barbuda, Martinique (+8 more), Saint Vincent, Trinidad and Tobago, Barbados, Saint Lucia, Dominica, Saint Kitts and Nevis, Saint Martin, USA
Inside
$4,819
Oceanview
$5,039
Balcony
-
Suite
-
From
US$4,819
Per Person
View Trip
15 Day An Extended Journey Of Tropical Radiance And Sun-kissed Splendour with Explora Journeys
Cruise
 (1)

15 Days (14 Nights) San Juan to Miami
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 26 March 2026
Visit: Puerto Rico, Bonaire, Curacao, Aruba (+4 more), Saint Barthelemy, Antigua and Barbuda, Dominican Republic, USA
Inside
-
Oceanview
-
Balcony
$8,170
Suite
$8,550
From
US$8,170
Per Person
View Trip
8 Day A Journey Through Shimmering Island History & Mesmerisingly Cultures with Explora Journeys
Cruise

8 Days (7 Nights) San Juan to Miami
Cruise Line: Explora Journeys
Ship: Explora IV
Departure: 27 November 2027
Visit: Puerto Rico, Saint Barthelemy, Virgin Islands, Dominican Republic, Bahamas, USA
Inside
-
Oceanview
-
Balcony
$3,915
Suite
$4,770
From
US$3,915
Per Person
View Trip
8 Day A Journey Savy New Year's Celebrations & Caribbean Conviviality with Explora Journeys
Cruise
 (1)

8 Days (7 Nights) San Juan to Miami
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 29 December 2025
Visit: Puerto Rico, Anguilla, Virgin Islands, Dominican Republic, USA
Inside
-
Oceanview
-
Balcony
$5,320
Suite
$6,125
From
US$5,320
Per Person
View Trip
8 Day A Journey Into Tropical Marvels & Enchanting Coastal Discovery with Explora Journeys
Cruise

8 Days (7 Nights) San Juan to Miami
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 07 March 2027
Visit: Puerto Rico, Saint Martin, Saint Barthelemy, Saint Kitts and Nevis, Turks and Caicos Islands, USA
Inside
-
Oceanview
-
Balcony
$4,535
Suite
$5,285
From
US$4,535
Per Person
View Trip
15 Day San Juan to Fort Lauderdale with Silversea
Cruise

15 Days (14 Nights) San Juan to Fort Lauderdale
Cruise Line: Silversea
Ship: Silver Ray
Departure: 24 February 2026
Visit: Puerto Rico, Virgin Islands, Saint Barthelemy, Antigua and Barbuda (+7 more), Saint Vincent, Saint Lucia, Barbados, Martinique, Guadeloupe, Saint Kitts and Nevis, USA
Inside
-
Oceanview
-
Balcony
$9,300
Suite
$11,000
From
US$9,300
Per Person
View Trip
8 Day A Journey to Island Rhythms & Tranquil Bahamian Bliss with Explora Journeys
Cruise
 (1)

8 Days (7 Nights) San Juan to Miami
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jan 2028 to Jan 2028
Visit: Puerto Rico, Virgin Islands, Guadeloupe, Saint Barthelemy, Bahamas, USA
Inside
-
Oceanview
-
Balcony
$4,180
Suite
$4,785
From
US$4,180
Per Person
View Trip
28 Day Panama Canal and Caribbean Adventurer with Princess
Cruise
 (5)

28 Days (27 Nights) San Juan to Los Angeles
Cruise Line: Princess
Ship: Grand Princess
Departure: 05 April 2026
Visit: Puerto Rico, Virgin Islands, Saint Kitts and Nevis, Aruba (+8 more), Curacao, Bonaire, Dominican Republic, Turks and Caicos Islands, USA, Panama, Costa Rica, Mexico
Inside
$2,604
Oceanview
$2,864
Balcony
$4,789
Suite
$6,364
From
US$2,604
Per Person
View Trip
8 Day Southern Caribbean with ABC Islands with Princess
Cruise
 (6)

8 Days (7 Nights) San Juan to Fort Lauderdale
Cruise Line: Princess
Ship: Crown Princess
Departure: 28 March 2027
Visit: Puerto Rico, Saint Martin, Aruba, Curacao, USA
Inside
$604
Oceanview
$754
Balcony
$1,179
Suite
$1,404
From
US$604
Per Person
View Trip
8 Day A Journey Through the Caribbean's Elegant Charm & Vibrant Soul with Explora Journeys
Cruise

8 Days (7 Nights) San Juan to Miami
Cruise Line: Explora Journeys
Ship: Explora IV
Departure: 22 January 2028
Visit: Puerto Rico, Saint Barthelemy, Virgin Islands, Dominican Republic, Bahamas, USA
Inside
-
Oceanview
-
Balcony
$4,440
Suite
$5,410
From
US$4,440
Per Person
View Trip
12 Day Southern Caribbean Islander with Princess
Cruise
 (5)

12 Days (11 Nights) San Juan to Fort Lauderdale
Cruise Line: Princess
Ship: Grand Princess
Departure: 05 April 2026
Visit: Puerto Rico, Virgin Islands, Saint Kitts and Nevis, Aruba (+5 more), Curacao, Bonaire, Dominican Republic, Turks and Caicos Islands, USA
Inside
$865
Oceanview
$945
Balcony
$1,510
Suite
$1,975
From
US$865
Per Person
View Trip
8 Day Eastern Caribbean Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) San Juan to Fort Lauderdale
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 19 April 2026
Visit: Puerto Rico, Saint Martin, Virgin Islands, Saint Kitts and Nevis, Bahamas, USA
Latest Offer
Exclusive Savings
Inside
$559
Oceanview
$637
Balcony
$941
Suite
$1,622
From
US$559
Save 331
Per Person
View Trip
15 Day An Extended Journey Into Island Delights, Hidden Coves & Chic Coastlines with Explora Journeys
Cruise

15 Days (14 Nights) San Juan to San Juan
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 01 November 2026
Visit: Puerto Rico, Virgin Islands, Saint Kitts and Nevis, Saint Barthelemy (+4 more), Anguilla, USA, Turks and Caicos Islands, Dominican Republic
Inside
-
Oceanview
-
Balcony
$8,020
Suite
$9,370
From
US$8,020
Per Person
View Trip
17 Day An Extended Journey of Relaxing Waters & Blissful Shores with Explora Journeys
Cruise

17 Days (16 Nights) San Juan to Miami
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 12 February 2027
Visit: Puerto Rico, Virgin Islands, Antigua and Barbuda, Guadeloupe, Dominican Republic, USA, Anguilla
Inside
-
Oceanview
-
Balcony
$9,335
Suite
$11,395
From
US$9,335
Per Person
View Trip
29 Day San Juan to Lisbon with Silversea
Cruise

29 Days (28 Nights) San Juan to Lisbon
Cruise Line: Silversea
Ship: Silver Ray
Departure: 24 February 2026
Visit: Puerto Rico, Virgin Islands, Saint Barthelemy, Antigua and Barbuda (+9 more), Saint Vincent, Saint Lucia, Barbados, Martinique, Guadeloupe, Saint Kitts and Nevis, USA, Bermuda, Portugal
Inside
-
Oceanview
-
Balcony
$10,900
Suite
$20,100
From
US$10,900
Per Person
View Trip
16 Day An Extended Journey Through Caribbean Cinematic Paradise with Explora Journeys
Cruise

16 Days (15 Nights) San Juan to San Juan
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 06 January 2026
Visit: Puerto Rico, Saint Barthelemy, Antigua and Barbuda, Virgin Islands (+6 more), Anguilla, USA, Guadeloupe, Grenada, Barbados, Montserrat
Inside
-
Oceanview
-
Balcony
$8,460
Suite
$8,640
From
US$8,460
Per Person
View Trip
10 Day Southern Caribbean Cruise: St.barts, Antigua & Tortola with Azamara Cruises
Cruise
 (2)

10 Days (9 Nights) San Juan to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 05 January 2027
Visit: Puerto Rico, Virgin Islands, Saint Barthelemy, Saint Martin, Antigua and Barbuda, Saint Kitts and Nevis, USA
Inside
$2,689
Oceanview
$3,319
Balcony
$3,969
Suite
$6,119
From
US$2,689
Per Person
View Trip
18 Day An Extended Journey Into Tropical Utopia, Coral Wonders & Blissful Beaches with Explora Journeys
Cruise

18 Days (17 Nights) San Juan to Miami
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 20 February 2026
Visit: Puerto Rico, Aruba, Curacao, Bonaire (+7 more), Barbados, Guadeloupe, Saint Martin, Virgin Islands, Antigua and Barbuda, Anguilla, USA
Inside
-
Oceanview
-
Balcony
$9,800
Suite
$10,760
From
US$9,800
Per Person
View Trip
9 Day A Journey Of Spectacular Festivities & Caribbean Wonders with Explora Journeys
Cruise

9 Days (8 Nights) San Juan to Miami
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 28 December 2026
Visit: Puerto Rico, Antigua and Barbuda, Guadeloupe, Virgin Islands, Dominican Republic, USA
Inside
-
Oceanview
-
Balcony
$6,320
Suite
$7,720
From
US$6,320
Per Person
View Trip
9 Day San Juan to Miami with Silversea
Cruise

9 Days (8 Nights) San Juan to Miami
Cruise Line: Silversea
Ship: Silver Nova
Departure: 29 December 2026
Visit: Puerto Rico, Virgin Islands, Dominica, Antigua and Barbuda, USA
Inside
-
Oceanview
-
Balcony
$7,500
Suite
$8,600
From
US$7,500
Per Person
View Trip
16 Day An Extended Journey Of Paradise Beauty And Colourful Shores with Explora Journeys
Cruise
 (1)

16 Days (15 Nights) San Juan to San Juan
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 11 March 2026
Visit: Puerto Rico, Anguilla, Antigua and Barbuda, Saint Martin (+6 more), Virgin Islands, USA, Guadeloupe, Barbados, Martinique, Saint Kitts and Nevis
Inside
-
Oceanview
-
Balcony
$7,265
Suite
$8,115
From
US$7,265
Per Person
View Trip
8 Day A Journey From San Juan To Miami with Explora Journeys
Cruise
 (1)

8 Days (7 Nights) San Juan to Miami
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 11 March 2026
Visit: Puerto Rico, Anguilla, Antigua and Barbuda, Saint Martin, Virgin Islands, USA
Inside
-
Oceanview
-
Balcony
$3,915
Suite
$4,455
From
US$3,915
Per Person
View Trip
11 Day Caribbean Mystique with Regent Seven Seas
Cruise

11 Days (10 Nights) San Juan to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 30 March 2027
Visit: Puerto Rico, Virgin Islands, Saint Kitts and Nevis, Antigua and Barbuda (+5 more), Saint Barthelemy, Saint Martin, Dominican Republic, Bahamas, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,799
Suite
$7,199
From
US$6,799
Save 12,799
Per Person
View Trip
21 Day Sju To Mia with Oceania Cruises
Cruise

21 Days (20 Nights) San Juan to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 19 February 2027
Visit: Puerto Rico, Saint Barthelemy, Saint Martin, Saint Kitts and Nevis (+10 more), Antigua and Barbuda, Virgin Islands, USA, Cayman Islands, Jamaica, Aruba, Curacao, Bonaire, Dominican Republic, Bahamas
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,099
Suite
$12,299
From
US$8,099
Save 8,099
Per Person
View Trip
8 Day A Journey Across Turquoise Seas and Timeless Streets with Explora Journeys
Cruise

8 Days (7 Nights) San Juan to Miami
Cruise Line: Explora Journeys
Ship: Explora IV
Departure: 19 February 2028
Visit: Puerto Rico, Saint Martin, Guadeloupe, Anguilla, Bahamas, USA
Inside
-
Oceanview
-
Balcony
$4,440
Suite
$5,410
From
US$4,440
Per Person
View Trip
8 Day A Journey Into Caribbean Exploration & Island Delights with Explora Journeys
Cruise

8 Days (7 Nights) San Juan to Miami
Cruise Line: Explora Journeys
Ship: Explora III
Departure: 01 November 2026
Visit: Puerto Rico, Virgin Islands, Saint Kitts and Nevis, Saint Barthelemy, Anguilla, USA
Inside
-
Oceanview
-
Balcony
$4,235
Suite
$4,950
From
US$4,235
Per Person
View Trip
16 Day An Extended Journey Through Spectacular Nature And Historic Wonders with Explora Journeys
Cruise
 (1)

16 Days (15 Nights) San Juan to Miami
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 03 March 2026
Visit: Puerto Rico, Grenada, Saint Vincent, Barbados (+8 more), Martinique, Saint Barthelemy, Saint Kitts and Nevis, Anguilla, Antigua and Barbuda, Saint Martin, Virgin Islands, USA
Inside
-
Oceanview
-
Balcony
$7,470
Suite
$8,820
From
US$7,470
Per Person
View Trip
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