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Cruises from Fort Lauderdale to San Diego

Are you looking for a cruise from Fort Lauderdale to San Diego? April is the most popular month to cruise between Fort Lauderdale and San Diego and there are 7 departures available from two of the world's leading cruise lines.
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7 Cruises (7 Cruise Departures)
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) Fort Lauderdale to San Diego
Cruise Line: Princess
Ship: Island Princess
Departure: 13 January 2027
Visit: USA, Aruba, Panama, Costa Rica, Mexico
Princess Standard
Inside
$1,989
Oceanview
$2,089
Balcony
$2,889
Suite
$3,589
From
US$1,989
Per Person
View Trip
18 Day Panama Canal with Holland America
Cruise
 (3)

18 Days (17 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 11 April 2027
Visit: USA, Aruba, Panama, Costa Rica, El Salvador, Guatemala, Mexico
Fare Saver
Inside
$2,484
Oceanview
$2,684
Balcony
$3,916
Suite
$6,532
From
US$2,484
Per Person
View Trip
18 Day Panama Canal with Holland America
Cruise
 (2)

18 Days (17 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 10 April 2026
Visit: USA, Colombia, Panama, Costa Rica, El Salvador, Guatemala, Mexico
Fare Saver
Inside
$2,199
Oceanview
$2,709
Balcony
$3,549
Suite
$4,725
From
US$2,199
Per Person
View Trip
15 Day Panama Canal with Holland America
Cruise
 (3)

15 Days (14 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 14 March 2027
Visit: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Fare Saver
Inside
$2,189
Oceanview
$2,239
Balcony
$4,028
Suite
$8,144
From
US$2,189
Per Person
View Trip
30 Day Panama Canal & Eastern Caribbean with Holland America
Cruise
 (2)

30 Days (29 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 29 March 2026
Visit: USA, Puerto Rico, Virgin Islands, Antigua and Barbuda (+10 more), Dominica, Saint Lucia, Saint Kitts and Nevis, Bahamas, Colombia, Panama, Costa Rica, El Salvador, Guatemala, Mexico
Have It All Fare Option
Inside
$3,654
Oceanview
$4,553
Balcony
$5,895
Suite
$7,846
From
US$3,654
Per Person
View Trip
16 Day Panama Canal with Holland America
Cruise

16 Days (15 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Eurodam
Departure: 05 April 2026
Visit: USA, Colombia, Costa Rica, El Salvador, Guatemala, Mexico
Fare Saver
Inside
-
Oceanview
-
Balcony
$3,404
Suite
-
From
US$3,404
Per Person
View Trip
15 Day Panama Canal with Holland America
Cruise

15 Days (14 Nights) Fort Lauderdale to San Diego
Cruise Line: Holland America
Ship: Eurodam
Departure: 03 April 2027
Visit: USA, Colombia, Costa Rica, Guatemala, Mexico
Fare Saver
Inside
$2,209
Oceanview
$2,409
Balcony
$3,536
Suite
$6,133
From
US$2,209
Per Person
View Trip
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