Home > Cruises > USA Cruises > Cruises from USA to Italy

Cruises from USA to Italy

Are you looking for a cruise from USA to Italy? April is the most popular month to cruise between USA and Italy and there are 21 departures available from nine of the world's leading cruise lines.
Filter Results
Departures
Duration
15 Days
28 Days
Start & End Cities
Ship Size
Ship Features
Operators
Show More...
Price
$1,500pp
$22,180pp
Countries
Show More...
Filter Results
20 Cruises (21 Cruise Departures)
Cruise
 (3)

22 Days (21 Nights) Fort Lauderdale to Rome
Cruise Line: Princess
Departure: 18 February 2025
Countries Visited: USA, Portugal, Spain, Gibraltar (+2 more), Corsica, Italy
Exclusive Deal
INSIDE
$2,978
OCEANVIEW
-
BALCONY
$3,695
SUITE
$4,320
From (per person) 2,978
Cruise
 (6)

21 Days (20 Nights) Fort Lauderdale to Rome
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Mar 2025 to Feb 2026
Countries Visited: USA, Sint Maarten, Portugal, Spain (+3 more), France, Monaco, Italy
Companion Fly Free
INSIDE
-
OCEANVIEW
-
BALCONY
$11,875
SUITE
$19,300
Save (per person) 963
From (per person) 11,875
Cruise
 (1)

20 Days (19 Nights) Fort Lauderdale to Rome
Cruise Line: Princess
Departure: 27 March 2026
Countries Visited: USA, Portugal, Gibraltar, Corsica (+3 more), Italy, Montenegro, Greece
Exclusive Deal
INSIDE
$2,741
OCEANVIEW
-
BALCONY
$3,368
SUITE
$5,226
From (per person) 2,741
Cruise
 (2)

21 Days (20 Nights) Fort Lauderdale to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 05 March 2026
Countries Visited: USA, Spain, Gibraltar, France (+1 more), Italy
Exclusive Deal
INSIDE
$3,103
OCEANVIEW
$3,665
BALCONY
$4,406
SUITE
$5,902
From (per person) 3,103
Cruise
 (1)

16 Days (15 Nights) New York to Rome
Cruise Line: Norwegian Cruise Line
Departure: 31 March 2025
Countries Visited: USA, Bermuda, Portugal, Spain (+2 more), France, Italy
More At Sea Offer
INSIDE
$2,627
OCEANVIEW
-
BALCONY
$3,774
SUITE
$4,386
From (per person) 2,627
Cruise
 (2)

22 Days (21 Nights) Fort Lauderdale to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 22 March 2025
Countries Visited: USA, Spain, Gibraltar, France (+1 more), Italy
Exclusive Deal
INSIDE
$3,571
OCEANVIEW
$3,613
BALCONY
$4,504
SUITE
$5,097
From (per person) 3,571
Cruise
 (1)

15 Days (14 Nights) Fort Lauderdale to Rome
Cruise Line: Princess
Departure: 27 March 2026
Countries Visited: USA, Portugal, Gibraltar, Corsica (+1 more), Italy
Exclusive Deal
INSIDE
$1,772
OCEANVIEW
$2,613
BALCONY
$1,934
SUITE
$3,494
From (per person) 1,772
Cruise

17 Days (16 Nights) Miami to Rome
Cruise Line: Oceania Cruises
Departure: 14 April 2026
Countries Visited: USA, Bahamas, Bermuda, Portugal (+2 more), Spain, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$6,872
SUITE
$10,000
Save (per person) 2,048
From (per person) 6,872
Cruise

28 Days (27 Nights) Miami to Genoa
Cruise Line: MSC Cruises
Departure: 04 November 2024
Countries Visited: USA, Bahamas, Virgin Islands, Antigua and Barbuda (+6 more), Sint Maarten, Martinique, Barbados, Portugal, Spain, Italy
Save And Sail Offer
INSIDE
-
OCEANVIEW
$3,741
BALCONY
$4,226
SUITE
-
From (per person) 3,741
Cruise

16 Days (15 Nights) Fort Lauderdale to Rome
Cruise Line: Princess
Departure: 24 March 2025
Countries Visited: USA, Portugal, Gibraltar, Spain (+2 more), Corsica, Italy
Exclusive Deal
INSIDE
$1,591
OCEANVIEW
$1,993
BALCONY
$2,353
SUITE
$3,887
From (per person) 1,591
Cruise

16 Days (15 Nights) Fort Lauderdale to Rome
Cruise Line: Celebrity Cruises
Departure: 20 April 2025
Countries Visited: USA, Bermuda, Gibraltar, Spain (+1 more), Italy
Exclusive Deal
INSIDE
$2,076
OCEANVIEW
-
BALCONY
-
SUITE
$29,781
Save (per person) 3,579
From (per person) 2,076
Cruise

21 Days (20 Nights) Miami to Naples
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 06 April 2025
Countries Visited: USA, Sint Maarten, Antigua and Barbuda, Barbados (+4 more), Portugal, Spain, Sicily, Italy
Save And Sail Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$4,210
SUITE
$5,830
From (per person) 4,210
Cruise

17 Days (16 Nights) Miami to Rome
Cruise Line: Regent Seven Seas
Departure: 15 April 2027
Countries Visited: USA, Bermuda, Spain, Corsica (+1 more), Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$14,798
SUITE
$16,570
Save (per person) 7,382
From (per person) 14,798
Cruise

22 Days (21 Nights) Miami to Rome
Cruise Line: Oceania Cruises
Departure: 07 April 2026
Countries Visited: USA, Bermuda, Portugal, Gibraltar (+5 more), Spain, France, Italy, Corsica, Sardinia
Exclusive Deal
INSIDE
$7,917
OCEANVIEW
$9,264
BALCONY
$10,452
SUITE
$14,768
Save (per person) 2,053
From (per person) 7,917
Cruise

21 Days (20 Nights) Miami to Rome
Cruise Line: Seabourn
Ship: Encore
Departure: 28 April 2025
Countries Visited: USA, Portugal, Gibraltar, Corsica (+1 more), Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$11,403
SUITE
-
From (per person) 11,403
Cruise

24 Days (23 Nights) Miami to Genoa
Cruise Line: MSC Cruises
Departure: 08 November 2024
Countries Visited: USA, Virgin Islands, Antigua and Barbuda, Sint Maarten (+5 more), Martinique, Barbados, Portugal, Spain, Italy
Save And Sail Offer
INSIDE
$2,844
OCEANVIEW
$3,222
BALCONY
$3,746
SUITE
$6,588
From (per person) 2,844
Cruise

19 Days (18 Nights) Miami to Rome
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 09 April 2026
Countries Visited: USA, Virgin Islands, Antigua and Barbuda, Spain (+3 more), Morocco, France, Italy
Early Booking Offer
INSIDE
$2,787
OCEANVIEW
$3,185
BALCONY
$3,495
SUITE
$5,260
From (per person) 2,787
Cruise

17 Days (16 Nights) Tampa to Rome
Cruise Line: Celebrity Cruises
Departure: 12 April 2025
Countries Visited: USA, Bermuda, Gibraltar, Spain (+1 more), Italy
Exclusive Deal
INSIDE
$1,838
OCEANVIEW
$2,019
BALCONY
$2,966
SUITE
$9,168
Save (per person) 3,555
From (per person) 1,838
Cruise

15 Days (14 Nights) New York to Rome
Cruise Line: Royal Caribbean
Departure: 27 April 2025
Countries Visited: USA, Portugal, Spain, Italy
Exclusive Deal
INSIDE
$2,320
OCEANVIEW
$2,963
BALCONY
$2,981
SUITE
-
Save (per person) 1,039
From (per person) 2,320
Cruise

23 Days (22 Nights) Miami to Rome
Cruise Line: MSC Cruises
Departure: 08 November 2024
Countries Visited: USA, Virgin Islands, Antigua and Barbuda, Sint Maarten (+5 more), Martinique, Barbados, Portugal, Spain, Italy
Save And Sail Offer
INSIDE
-
OCEANVIEW
$2,976
BALCONY
$3,374
SUITE
$6,245
From (per person) 2,976
Results: 20 results

No Results found. Try changing your search filters.

Country Routes