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Cruises from USA to Spain

Are you looking for a cruise from USA to Spain? April is the most popular month to cruise between USA and Spain and there are 30 departures available from twelve of the world's leading cruise lines.
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14 Days
157 Days
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29 Cruises (30 Cruise Departures)
82 Day Grand Arctic Adventure with Regent Seven Seas
Cruise

82 Days (81 Nights) New York to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 29 June 2026
Countries Visited: USA, Canada, Greenland, Iceland (+16 more), Scotland, Ireland, England, Wales, France, Belgium, Holland, Sweden, Denmark, Germany, Lithuania, Finland, Estonia, Norway, Portugal, Spain
Early Booking Saving
INSIDE
-
OCEANVIEW
-
BALCONY
$68,699
SUITE
$73,099
Save (per person) 102,499
From (per person) 68,699
View Trip
15 Day Spain & Portugal Transatlantic with Royal Caribbean
Cruise

15 Days (14 Nights) Orlando to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 23 April 2026
Countries Visited: USA, Portugal, Spain
Latest OfferExclusive Solo Offer
INSIDE
$883
OCEANVIEW
$1,126
BALCONY
$1,669
SUITE
$6,349
Save (per person) 421
From (per person) 883
View Trip
16 Day Transatlantic Repositioning Cruise From New York to Barcelona with Norwegian Cruise Line
Cruise

16 Days (15 Nights) New York to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Gem
Departure: 09 April 2026
Countries Visited: USA, Canada, Portugal, Spain (+1 more), France
INSIDE
$1,318
OCEANVIEW
$1,468
BALCONY
$2,417
SUITE
$2,618
From (per person) 1,318
View Trip
15 Day Cultural Crossing With Morocco & Spain with Holland America
Cruise
 (2)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departure: 09 April 2027
Countries Visited: USA, Morocco, Spain
Exclusive Deal
INSIDE
$1,044
OCEANVIEW
$1,344
BALCONY
$1,524
SUITE
$3,744
From (per person) 1,044
View Trip
24 Day A Grand Journey From Caribbean Delights To Iberian Spectacle with Explora Journeys
Cruise
 (1)

24 Days (23 Nights) San Juan to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 02 April 2026
Countries Visited: Puerto Rico, Antigua and Barbuda, Saint Barthelemy, Dominican Republic (+4 more), USA, Bermuda, Portugal, Spain
Best Available FareGrand Journey Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$10,615
SUITE
$12,575
From (per person) 10,615
View Trip
26 Day Sunlit Isles To Iberia with Oceania Cruises
Cruise
 (1)

26 Days (25 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 27 March 2026
Countries Visited: USA, Bermuda, Portugal, Spain (+2 more), Morocco, Gibraltar
Exclusive Deal
INSIDE
$6,199
OCEANVIEW
$6,599
BALCONY
$8,899
SUITE
$12,399
Save (per person) 6,199
From (per person) 6,199
View Trip
16 Day Spain & Bermuda Transatlantic with Royal Caribbean
Cruise
 (2)

16 Days (15 Nights) Fort Lauderdale to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 26 April 2026
Countries Visited: USA, Bahamas, Bermuda, Portugal (+1 more), Spain
Latest OfferExclusive Solo Offer
INSIDE
$967
OCEANVIEW
$1,057
BALCONY
$1,459
SUITE
-
Save (per person) 383
From (per person) 967
View Trip
15 Day New York Transatlantic to Spain with Virgin Voyages
Cruise
 (1)

15 Days (14 Nights) New York to Barcelona
Cruise Line: Virgin Voyages
Ship: Valiant Lady
Departure: 25 April 2026
Countries Visited: USA, Portugal, Morocco, Spain
Swing Into Savings Best Rate
INSIDE
-
OCEANVIEW
-
BALCONY
$2,170
SUITE
$5,592
From (per person) 2,170
View Trip
17 Day A Grand Journey From Levely Latin Charm & Tropical Delights To Modernist Marvels with Explora Journeys
Cruise

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 09 March 2026
Countries Visited: USA, Puerto Rico, Saint Martin, Spain (+1 more), Gibraltar
Best Available FareGrand Journey Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$6,545
SUITE
$7,525
From (per person) 6,545
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise

14 Days (13 Nights) Miami to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 19 April 2026
Countries Visited: USA, Saint Martin, Portugal, Spain
Escape To Sea
INSIDE
$939
OCEANVIEW
$1,069
BALCONY
$1,279
SUITE
$4,099
From (per person) 939
View Trip
17 Day Transatlantic Repositioning Cruise From New York to Barcelona with Norwegian Cruise Line
Cruise
 (1)

17 Days (16 Nights) New York to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Escape
Departure: 26 September 2026
Countries Visited: USA, Canada, Portugal, Spain (+1 more), Gibraltar
INSIDE
$1,788
OCEANVIEW
$2,128
BALCONY
$2,588
SUITE
$3,067
From (per person) 1,788
View Trip
15 Day Bermuda & Iberia with Oceania Cruises
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 April 2026
Countries Visited: USA, Bermuda, Portugal, Gibraltar (+1 more), Spain
Exclusive DealSolo Offer
INSIDE
$2,899
OCEANVIEW
$3,649
BALCONY
$4,399
SUITE
$6,199
Save (per person) 2,899
From (per person) 2,899
View Trip
157 Day Azamara World Voyage with Azamara Cruises
Cruise
 (3)

157 Days (156 Nights) Miami to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 06 January 2026
Countries Visited: USA, Mexico, Panama, Ecuador (+31 more), Peru, Chile, Pitcairn Islands, French Polynesia, Cook Islands, New Zealand, Australia, Papua New Guinea, Palau, Philippines, China, Vietnam, Thailand, Singapore, Malaysia, Indonesia, Sri Lanka, India, Maldives, Seychelles, Kenya, Tanzania, France, Madagascar, South Africa, Namibia, Cape Verde, Spain, Morocco, Gibraltar, Italy
INSIDE
-
OCEANVIEW
$48,939
BALCONY
$60,939
SUITE
$90,939
From (per person) 48,939
View Trip
17 Day A Grand Journey From Miami To Barcelona with Explora Journeys
Cruise
 (1)

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 09 April 2026
Countries Visited: USA, Bermuda, Portugal, Spain
Best Available FareGrand Journey Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$7,310
SUITE
$8,760
From (per person) 7,310
View Trip
15 Day Spanish Passage with Princess
Cruise
 (3)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departure: 05 March 2026
Countries Visited: USA, Spain
Exclusive DealSummer Swing Sale
INSIDE
$999
OCEANVIEW
$1,079
BALCONY
$1,189
SUITE
$1,589
From (per person) 999
View Trip
17 Day A Grand Journey From Atlantic Exploration To Mediterranean Delights with Explora Journeys
Cruise

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 08 March 2027
Countries Visited: USA, Puerto Rico, Saint Martin, Portugal (+1 more), Spain
Explora Early Booking BenefitGrand Journey Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$6,925
SUITE
$7,980
From (per person) 6,925
View Trip
16 Day Transatlantic Repositioning Cruise From Miami to Barcelona with Norwegian Cruise Line
Cruise
 (1)

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 14 April 2026
Countries Visited: USA, Portugal, Spain, Italy (+1 more), France
INSIDE
$1,819
OCEANVIEW
$1,989
BALCONY
$2,469
SUITE
$3,689
From (per person) 1,819
View Trip
14 Day Atlantic Ocean Passage with Viking Cruises
Cruise
 (8)

14 Days (13 Nights) Fort Lauderdale to Barcelona
Operated By: Viking Cruises
Ship: Viking Mars
Departures: Feb 2026 to Jan 2027
Countries Visited: USA, Sint Maarten, Portugal, Spain
Viking $799 Air Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$2,999
SUITE
$4,999
From (per person) 2,999
View Trip
15 Day Cultural Crossing With Madeira And Gibraltar with Holland America
Cruise
 (2)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departure: 08 April 2026
Countries Visited: USA, Portugal, Spain
Exclusive Deal
INSIDE
$869
OCEANVIEW
$999
BALCONY
$1,349
SUITE
$2,999
From (per person) 869
View Trip
16 Day Transatlantic Repositioning Cruise From Miami to Barcelona with Norwegian Cruise Line
Cruise

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Pearl
Departure: 11 April 2026
Countries Visited: USA, Portugal, Spain
INSIDE
$1,319
OCEANVIEW
$1,469
BALCONY
$2,219
SUITE
$2,469
From (per person) 1,319
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise

20 Days (19 Nights) Miami to Palma de Mallorca
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 19 April 2026
Countries Visited: USA, Saint Martin, Portugal, Spain (+2 more), France, Italy
Escape To Sea
INSIDE
$1,469
OCEANVIEW
$1,649
BALCONY
$1,909
SUITE
-
From (per person) 1,469
View Trip
17 Day Brilliant Bermuda & Iberia with Oceania Cruises
Cruise

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 31 March 2027
Countries Visited: USA, Bermuda, Portugal, Spain (+1 more), Gibraltar
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$5,099
SUITE
$7,299
Save (per person) 5,099
From (per person) 5,099
View Trip
16 Day Spain & Portugal Transatlantic with Celebrity Cruises
Cruise

16 Days (15 Nights) Fort Lauderdale to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departure: 26 April 2026
Countries Visited: USA, Bermuda, Portugal, Spain
Exclusive DealExclusive Solo Offer
INSIDE
$1,388
OCEANVIEW
$1,736
BALCONY
$1,964
SUITE
$6,746
Save (per person) 824
From (per person) 1,388
View Trip
15 Day Atlantic Isle Exploration with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 07 April 2026
Countries Visited: USA, Bermuda, Portugal, Spain
Early Booking Saving
INSIDE
-
OCEANVIEW
-
BALCONY
$7,999
SUITE
$9,099
Save (per person) 14,199
From (per person) 7,999
View Trip
15 Day Transatlantic to Spain & Morocco with Virgin Voyages
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 26 April 2026
Countries Visited: USA, Spain, Morocco
Swing Into Savings Best Rate
INSIDE
$1,611
OCEANVIEW
$1,526
BALCONY
$1,667
SUITE
$5,586
From (per person) 1,526
View Trip
17 Day Spain & Bahamas Transatlantic with Royal Caribbean
Cruise

17 Days (16 Nights) Galveston to Barcelona
Cruise Line: Royal Caribbean
Ship: Harmony of the Seas
Departure: 16 March 2026
Countries Visited: USA, Bahamas, Spain
Latest OfferExclusive Solo Offer
INSIDE
$1,109
OCEANVIEW
$1,519
BALCONY
$1,691
SUITE
-
Save (per person) 498
From (per person) 1,109
View Trip
16 Day Spain & Portugal Transatlantic with Royal Caribbean
Cruise

16 Days (15 Nights) New York to Barcelona
Cruise Line: Royal Caribbean
Ship: Odyssey of the Seas
Departure: 15 March 2026
Countries Visited: USA, Portugal, Spain, Gibraltar
Latest OfferExclusive Solo Offer
INSIDE
$1,271
OCEANVIEW
$1,401
BALCONY
$1,744
SUITE
-
Save (per person) 559
From (per person) 1,271
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise

14 Days (13 Nights) Miami to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 09 April 2026
Countries Visited: USA, Virgin Islands, Spain
Grand Voyages Sale
INSIDE
$724
OCEANVIEW
$924
BALCONY
$1,114
SUITE
$2,364
From (per person) 724
View Trip
29 Day Splendor Across The Seas with Regent Seven Seas
Cruise

29 Days (28 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 13 March 2026
Countries Visited: USA, Bermuda, Portugal, Spain (+3 more), Morocco, Italy, France
Early Booking Saving
INSIDE
-
OCEANVIEW
-
BALCONY
$18,399
SUITE
$21,199
Save (per person) 30,199
From (per person) 18,399
View Trip
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