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Cruises from USA to Spain

Are you looking for a cruise from USA to Spain? April is the most popular month to cruise between USA and Spain and there are 44 departures available from eleven of the world's leading cruise lines.
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102 Days
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42 Cruises (44 Cruise Departures)
15 Day Spain & Morocco Transatlantic with Virgin Voyages
Cruise
 (5)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departure: 02 May 2027
Visit: USA, Spain, Morocco
With Love From the World
Inside
$1,476
Oceanview
$1,742
Balcony
$1,809
Suite
$5,740
From
US$1,476
Per Person
View Trip
14 Day Atlantic Ocean Passage with Viking Cruises
Cruise
 (8)

14 Days (13 Nights) Fort Lauderdale to Barcelona
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Jan 2027 to Feb 2028
Visit: USA, Sint Maarten, Portugal, Spain
Viking $799 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,099
Suite
$5,499
From
US$3,099
Save 100
Per Person
View Trip
16 Day Transatlantic Repositioning Cruise From Miami to Barcelona with Norwegian Cruise Line
Cruise
 (1)

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Pearl
Departure: 11 April 2026
Visit: USA, Portugal, Spain
Inside
$999
Oceanview
$1,099
Balcony
$1,489
Suite
$1,869
From
US$999
Per Person
View Trip
15 Day Spain & Gibraltar Transatlantic with Royal Caribbean
Cruise
 (1)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Royal Caribbean
Ship: Rhapsody of the Seas
Departure: 19 April 2027
Visit: USA, Bahamas, Gibraltar, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$940
Oceanview
$1,110
Balcony
$1,811
Suite
$2,790
From
US$940
Save 308
Per Person
View Trip
15 Day New York Transatlantic to Spain with Virgin Voyages
Cruise
 (1)

15 Days (14 Nights) New York to Barcelona
Cruise Line: Virgin Voyages
Ship: Valiant Lady
Departure: 25 April 2026
Visit: USA, Portugal, Morocco, Spain
With Love From the World
Inside
-
Oceanview
$2,086
Balcony
$2,366
Suite
$7,630
From
US$2,086
Per Person
View Trip
15 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

15 Days (14 Nights) Philadelphia to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Pearl
Departure: 09 April 2028
Visit: USA, Portugal, Spain, France
Inside
$1,599
Oceanview
$1,749
Balcony
$2,550
Suite
$2,909
From
US$1,599
Per Person
View Trip
15 Day Spanish Passage with Princess
Cruise
 (6)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Mar 2026 to Mar 2027
Visit: USA, Spain
Princess Standard
Princess Premier
Sanctuary Collection
Exclusive Savings
Inside
$998
Oceanview
$1,259
Balcony
$1,769
Suite
$2,189
From
US$998
Save 230
Per Person
View Trip
13 Day A Journey From Turquoise Shores To Volcanic Isles with Explora Journeys
Cruise

13 Days (12 Nights) Miami to Lanzarote
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 09 March 2026
Visit: USA, Puerto Rico, Saint Martin, Spain
A Suite Invitation
Inside
-
Oceanview
-
Balcony
$5,180
Suite
$5,845
From
US$5,180
Per Person
View Trip
13 Day Transatlantic Repositioning Cruise From Miami To Barcelona with Norwegian Cruise Line
Cruise
 (1)

13 Days (12 Nights) Miami to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 23 May 2027
Visit: USA, Portugal, Spain
Inside
$1,529
Oceanview
$1,829
Balcony
$1,919
Suite
$2,899
From
US$1,529
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) New York to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 19 April 2026
Visit: USA, Canada, Portugal, Spain, France
Grand Voyages Sale
Inside
$870
Oceanview
$1,040
Balcony
$1,270
Suite
$7,095
From
US$870
Per Person
View Trip
17 Day A Journey Through Vibrant Cultures Across The Atlantic & The Mediterranean with Explora Journeys
Cruise
 (1)

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 19 March 2028
Visit: USA, Puerto Rico, Antigua and Barbuda, Portugal, Spain
A Suite Invitation
Inside
-
Oceanview
-
Balcony
$8,340
Suite
$9,405
From
US$8,340
Per Person
View Trip
15 Day Transatlantic to Spain & Morocco with Virgin Voyages
Cruise
 (1)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 26 April 2026
Visit: USA, Spain, Morocco
With Love From the World
Inside
$1,386
Oceanview
$1,526
Balcony
$1,666
Suite
$5,320
From
US$1,386
Per Person
View Trip
15 Day Spain & Portugal Transatlantic with Royal Caribbean
Cruise

15 Days (14 Nights) Orlando to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 26 April 2027
Visit: USA, Portugal, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$1,143
Oceanview
$1,412
Balcony
$1,832
Suite
$3,097
From
US$1,143
Save 407
Per Person
View Trip
17 Day A Grand Journey From Miami To Barcelona with Explora Journeys
Cruise
 (1)

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 09 April 2026
Visit: USA, Bermuda, Portugal, Spain
A Suite Invitation
Inside
-
Oceanview
-
Balcony
$7,310
Suite
$8,250
From
US$7,310
Per Person
View Trip
15 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

15 Days (14 Nights) Orlando to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 18 April 2027
Visit: USA, Portugal, Spain
Inside
$1,439
Oceanview
-
Balcony
$2,267
Suite
$2,577
From
US$1,439
Per Person
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise

14 Days (13 Nights) Miami to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 19 April 2026
Visit: USA, Saint Martin, Portugal, Spain
Inside
$518
Oceanview
$808
Balcony
$888
Suite
-
From
US$518
Per Person
View Trip
15 Day Cultural Crossing With Morocco & Spain with Holland America
Cruise
 (2)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departure: 09 April 2027
Visit: USA, Morocco, Spain
Book Early & Have It All Fare Option
Inside
$1,044
Oceanview
$1,344
Balcony
$1,524
Suite
$3,680
From
US$1,044
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise

20 Days (19 Nights) Miami to Palma de Mallorca
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 19 April 2026
Visit: USA, Saint Martin, Portugal, Spain, France, Italy
Bonus Onboard Credit
Inside
$1,119
Oceanview
$1,359
Balcony
$1,659
Suite
$3,526
From
US$1,119
Per Person
View Trip
15 Day South Beach To Sant Sebasti with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 10 March 2028
Visit: USA, Bermuda, Portugal, Gibraltar, Spain
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$2,942
Oceanview
$3,330
Balcony
$4,494
Suite
$6,240
From
US$2,942
Save 3,056
Per Person
View Trip
15 Day Gilded Crossing with Regent Seven Seas
Cruise

15 Days (14 Nights) New York to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 27 April 2027
Visit: USA, Bermuda, Portugal, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$8,901
From
US$8,901
Save 16,197
Per Person
View Trip
15 Day Cultural Crossing With Madeira And Gibraltar with Holland America
Cruise
 (2)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departure: 08 April 2026
Visit: USA, Portugal, Spain
Have It All Fare Option
Inside
$1,159
Oceanview
$1,159
Balcony
$1,489
Suite
$2,839
From
US$1,159
Per Person
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise

16 Days (15 Nights) Miami to Palma de Mallorca
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 10 April 2027
Visit: USA, Saint Martin, Portugal, Spain
Bonus Onboard Credit
Inside
-
Oceanview
-
Balcony
$1,970
Suite
-
From
US$1,970
Per Person
View Trip
16 Day Spain & Morocco Transatlantic with Royal Caribbean
Cruise
 (2)

16 Days (15 Nights) Fort Lauderdale to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 23 April 2027
Visit: USA, Bahamas, Morocco, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$1,327
Oceanview
$1,527
Balcony
$1,857
Suite
$3,574
From
US$1,327
Save 476
Per Person
View Trip
15 Day Transatlantic Miami to Morocco & Spain with Virgin Voyages
Cruise
 (1)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 24 April 2027
Visit: USA, Spain, Morocco
With Love From the World
Inside
$1,473
Oceanview
$1,805
Balcony
$1,872
Suite
$6,510
From
US$1,473
Per Person
View Trip
15 Day Bermuda & Iberia with Oceania Cruises
Cruise
 (3)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 April 2026
Visit: USA, Bermuda, Portugal, Gibraltar, Spain
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,665
Suite
-
From
US$3,665
Save 5,133
Per Person
View Trip
24 Day Across The Atlantic with Oceania Cruises
Cruise
 (3)

24 Days (23 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 25 March 2028
Visit: USA, Bermuda, Portugal, Spain (+4 more), France, Italy, Corsica, Monaco
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$5,343
Oceanview
$6,653
Balcony
$8,011
Suite
$11,115
From
US$5,343
Save 5,555
Per Person
View Trip
17 Day A Grand Journey From Atlantic Exploration To Mediterranean Delights with Explora Journeys
Cruise

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 08 March 2027
Visit: USA, Puerto Rico, Saint Martin, Portugal, Spain
A Suite Invitation
Inside
-
Oceanview
-
Balcony
$7,990
Suite
$9,040
From
US$7,990
Per Person
View Trip
15 Day Atlantic Isle Exploration with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 07 April 2026
Visit: USA, Bermuda, Portugal, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,547
Suite
$9,233
From
US$8,547
Save 15,051
Per Person
View Trip
29 Day Splendor Across The Seas with Regent Seven Seas
Cruise

29 Days (28 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 13 March 2026
Visit: USA, Bermuda, Portugal, Spain, Morocco, Italy, France
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$20,086
Suite
$21,262
From
US$20,086
Save 32,612
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise

15 Days (14 Nights) Miami to Malaga
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 10 April 2027
Visit: USA, Saint Martin, Portugal, Spain
Bonus Onboard Credit
Inside
$1,208
Oceanview
$1,408
Balcony
$1,638
Suite
-
From
US$1,208
Per Person
View Trip
Results: 1-30 of 42

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