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Cruises from USA to Spain

Are you looking for a cruise from USA to Spain? April is the most popular month to cruise between USA and Spain and there are 39 departures available from thirteen of the world's leading cruise lines.
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37 Cruises (39 Departures)
37 Cruises (39 Departures)
Departures
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Duration
13 Days
138 Days
Start & End Cities
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Price
$700pp
$69,000pp
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17 Day A Journey Through Vibrant Cultures Across The Atlantic & The Mediterranean with Explora Journeys
Cruise
 (1)

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 19 March 2028
Visits: USA, Puerto Rico, Antigua and Barbuda, Portugal, Spain
Suite
$8,265
From (Per Person)
US$8,265
Per Person
View Trip
16 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Star
Departure: 01 March 2027
Visits: USA, Dominican Republic, Puerto Rico, Portugal, Spain
Inside
$1,679
Oceanview
$1,939
Balcony
$2,959
Suite
$3,489
From (Per Person)
US$1,679
Per Person
View Trip
15 Day Spanish Passage with Princess
Cruise
 (7)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departure: 28 March 2027
Visits: USA, Spain
Inside
$958
Oceanview
$1,142
Balcony
$1,372
Suite
$2,109
From (Per Person)
US$958
Per Person
View Trip
24 Day A Grand Journey Of Tropical Shores, Historic Streets & Renaissance Wonders with Explora Journeys
Cruise
 (1)

24 Days (23 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 19 March 2028
Visits: USA, Puerto Rico, Antigua and Barbuda, Portugal +4 more, Spain, France, Monaco, Italy
Suite
$12,975
From (Per Person)
US$12,975
Per Person
View Trip
24 Day Across The Atlantic with Oceania Cruises
Cruise
 (3)

24 Days (23 Nights) Miami to Barcelona
Cruise Line: Oceania
Ship: Oceania Marina
Departure: 25 March 2028
Visits: USA, Bermuda, Portugal, Spain +4 more, France, Italy, Corsica, Monaco
Your World Inclusions
Exclusive Savings
Inside
$5,449
Oceanview
$6,799
Balcony
$8,199
Suite
$11,399
From (Per Person)
US$5,449
Save 5,449
Per Person
View Trip
13 Day Transatlantic Repositioning Cruise From Miami To Barcelona with Norwegian Cruise Line
Cruise
 (1)

13 Days (12 Nights) Miami to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 23 May 2027
Visits: USA, Portugal, Spain
Inside
$1,499
Oceanview
$1,849
Balcony
$2,099
Suite
$3,149
From (Per Person)
US$1,499
Per Person
View Trip
15 Day Miami to Morocco & Spain Transatlantic with Virgin Voyages
Cruise
 (5)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departure: 02 May 2027
Visits: USA, Spain, Morocco
Inside
$1,106
Oceanview
$1,246
Balcony
$1,386
Suite
$5,530
From (Per Person)
US$1,106
Per Person
View Trip
15 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

15 Days (14 Nights) Orlando to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 18 April 2027
Visits: USA, Portugal, Spain
Inside
$1,359
Oceanview
-
Balcony
$1,909
Suite
$2,139
From (Per Person)
US$1,359
Per Person
View Trip
16 Day Spain & Morocco Transatlantic with Royal Caribbean
Cruise
 (2)

16 Days (15 Nights) Fort Lauderdale to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 23 April 2027
Visits: USA, Bahamas, Morocco, Spain
Exclusive Savings
Inside
$821
Oceanview
$971
Balcony
$1,344
Suite
$4,549
From (Per Person)
US$821
Save 421
Per Person
View Trip
20 Day Transatlantic Combination Cruise: Miami To Barcelona with Azamara Cruises
Cruise
 (5)

20 Days (19 Nights) Miami to Barcelona
Cruise Line: Azamara
Ship: Azamara Quest
Departure: 02 April 2028
Visits: USA, Bermuda, Portugal, Spain, Gibraltar
Azamara Always Included
Exclusive Savings
Inside
$3,514
Oceanview
$3,847
Balcony
$4,825
Suite
$6,953
From (Per Person)
US$3,514
Save 185
Per Person
View Trip
15 Day South Beach To Sant Sebasti with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania
Ship: Oceania Sirena
Departure: 10 March 2028
Visits: USA, Bermuda, Portugal, Gibraltar, Spain
Your World Inclusions
Exclusive Savings
Inside
$2,999
Oceanview
$3,399
Balcony
$4,599
Suite
$6,399
From (Per Person)
US$2,999
Save 2,999
Per Person
View Trip
15 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

15 Days (14 Nights) Philadelphia to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Pearl
Departure: 09 April 2028
Visits: USA, Portugal, Spain, France
Inside
$1,569
Oceanview
$1,719
Balcony
$2,569
Suite
$2,919
From (Per Person)
US$1,569
Per Person
View Trip
16 Day Spanish Passage with Princess
Cruise
 (7)

16 Days (15 Nights) Fort Lauderdale to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departure: 19 February 2028
Visits: USA, Spain, Gibraltar
Sanctuary Collection
Inside
$1,250
Oceanview
$1,475
Balcony
$2,150
Suite
$2,700
From (Per Person)
US$1,250
Per Person
View Trip
17 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

17 Days (16 Nights) New York to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Escape
Departure: 26 September 2026
Visits: USA, Canada, Portugal, Gibraltar, Spain
Inside
$1,669
Oceanview
$2,019
Balcony
$2,319
Suite
$2,369
From (Per Person)
US$1,669
Per Person
View Trip
15 Day Miami to Morocco & Spain Transatlantic with Virgin Voyages
Cruise
 (2)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 24 April 2027
Visits: USA, Spain, Morocco
Inside
$1,106
Oceanview
$1,246
Balcony
$1,386
Suite
$5,180
From (Per Person)
US$1,106
Per Person
View Trip
15 Day Cultural Crossing With Morocco & Spain with Holland America
Cruise
 (3)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Holland America
Ships: Oosterdam, Zuiderdam
Departures: Apr 2027 to Feb 2028
Visits: USA, Morocco, Spain
Book Early & Have It All Fare Option
Inside
$739
Oceanview
$829
Balcony
$1,079
Suite
$2,879
From (Per Person)
US$739
Per Person
View Trip
15 Day Transatlantic Aspirations with Oceania Cruises
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania
Ship: Oceania Sonata
Departure: 18 March 2028
Visits: USA, Spain
Your World Inclusions
Exclusive Savings
Balcony
$5,149
Suite
$6,599
From (Per Person)
US$5,149
Save 5,149
Per Person
View Trip
15 Day Spain & Portugal Transatlantic with Royal Caribbean
Cruise

15 Days (14 Nights) Orlando to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 26 April 2027
Visits: USA, Portugal, Spain
Exclusive Savings
Inside
$740
Oceanview
$890
Balcony
$1,283
Suite
$2,718
From (Per Person)
US$740
Save 395
Per Person
View Trip
16 Day Spain & Portugal Transatlantic with Celebrity Cruises
Cruise

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departure: 11 April 2027
Visits: USA, Portugal, Spain, Morocco
Exclusive Savings
Inside
$2,664
Oceanview
-
Balcony
$4,735
Suite
-
From (Per Person)
US$2,664
Save 1,434
Per Person
View Trip
24 Day A Grand Journey Into Island Whispers & Beauty-Rich Shores with Explora Journeys
Cruise

24 Days (23 Nights) San Juan to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 01 March 2027
Visits: Puerto Rico, Antigua and Barbuda, Anguilla, Virgin Islands +5 more, Turks and Caicos Islands, USA, Saint Martin, Portugal, Spain
Suite
$12,825
From (Per Person)
US$12,825
Per Person
View Trip
16 Day Elegance Of The Atlantic with Regent Seven Seas
Cruise

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 01 April 2028
Visits: USA, Bahamas, Portugal, Spain, Morocco
Exclusive Savings
Balcony
$8,299
Suite
$9,249
From (Per Person)
US$8,299
Save 15,299
Per Person
View Trip
15 Day Tropics To Iberia Crossing with Oceania Cruises
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania
Ship: Oceania Sonata
Departure: 29 March 2029
Visits: USA, Bahamas, Portugal, Spain
Your World Inclusions
Exclusive Savings
Balcony
$5,299
Suite
$6,899
From (Per Person)
US$5,299
Save 5,299
Per Person
View Trip
28 Day Springtime Atlantic Crossing with Regent Seven Seas
Cruise

28 Days (27 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 20 March 2028
Visits: USA, Dominican Republic, Puerto Rico, Saint Barthelemy +8 more, Dominica, Guadeloupe, Saint Kitts and Nevis, Virgin Islands, Bahamas, Portugal, Spain, Morocco
Exclusive Savings
Balcony
$15,149
Suite
$16,999
From (Per Person)
US$15,149
Save 24,149
Per Person
View Trip
15 Day Exuberant Bermuda & Azores with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 18 March 2028
Visits: USA, Bermuda, Portugal, Spain
Exclusive Savings
Balcony
$5,799
Suite
$6,899
From (Per Person)
US$5,799
Save 12,799
Per Person
View Trip
14 Day Atlantic Ocean Passage with Viking Cruises
Cruise

14 Days (13 Nights) Fort Lauderdale to Barcelona
Cruise Line: Viking
Ship: Viking Mars
Departures: Jan 2027 to Feb 2028
Visits: USA, Sint Maarten, Portugal, Spain
Balcony
$3,299
Suite
$5,699
From (Per Person)
US$3,299
Per Person
View Trip
18 Day Spain & Morocco Transatlantic with Royal Caribbean
Cruise

18 Days (17 Nights) New Orleans to Barcelona
Cruise Line: Royal Caribbean
Ship: Mariner of the Seas
Departure: 24 April 2027
Visits: USA, Morocco, Spain
Exclusive Savings
Inside
$979
Oceanview
$1,339
Balcony
$1,872
Suite
$4,936
From (Per Person)
US$979
Save 498
Per Person
View Trip
15 Day Gilded Crossing with Regent Seven Seas
Cruise

15 Days (14 Nights) New York to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 27 April 2027
Visits: USA, Bermuda, Portugal, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$11,099
From (Per Person)
US$11,099
Save 18,099
Per Person
View Trip
138 Day 2028 World Cruise: Fort Lauderdale to Barcelona with Crystal Cruises
New ReleaseCruise

138 Days (137 Nights) Fort Lauderdale to Barcelona
Cruise Line: Crystal
Ship: Crystal Symphony
Departure: 11 January 2028
Visits: USA, Mexico, Belize, Guatemala +34 more, Honduras, Costa Rica, Colombia, Panama, Ecuador, Peru, Chile, Pitcairn Islands, French Polynesia, American Samoa, Fiji, Vanuatu, New Caledonia, New Zealand, Australia, Indonesia, Philippines, Vietnam, Singapore, Malaysia, Thailand, India, Sri Lanka, Oman, United Arab Emirates, Saudi Arabia, Jordan, Egypt, Greece, Sicily, Malta, Tunisia, Italy, Spain
Oceanview
$69,000
Balcony
$88,000
Suite
$92,000
From (Per Person)
US$69,000
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise

18 Days (17 Nights) Miami to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 10 April 2027
Visits: USA, Saint Martin, Portugal, Spain, France
Inside
$994
Oceanview
$1,234
Balcony
$1,524
Suite
$4,944
From (Per Person)
US$994
Per Person
View Trip
13 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise

13 Days (12 Nights) Miami to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Jewel
Departure: 05 April 2028
Visits: USA, Portugal, Spain
Inside
$1,443
Oceanview
$1,593
Balcony
$2,293
Suite
$2,893
From (Per Person)
US$1,443
Per Person
View Trip
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