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Cruises from USA to Spain

Are you looking for a cruise from USA to Spain? April is the most popular month to cruise between USA and Spain and there are 31 departures available from eleven of the world's leading cruise lines.
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30 Cruises (31 Cruise Departures)
15 Day Spanish Passage with Princess
Cruise
 (7)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departure: 28 March 2027
Visit: USA, Spain
Princess Standard
Sanctuary Collection
Inside
$847
Oceanview
$949
Balcony
$1,212
Suite
$1,379
From
US$847
Per Person
View Trip
24 Day Across The Atlantic with Oceania Cruises
Cruise
 (3)

24 Days (23 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 25 March 2028
Visit: USA, Bermuda, Portugal, Spain (+4 more), France, Italy, Corsica, Monaco
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$5,449
Oceanview
$6,799
Balcony
$8,199
Suite
$11,399
From
US$5,449
Save 5,449
Per Person
View Trip
16 Day Spain & Morocco Transatlantic with Royal Caribbean
Cruise
 (2)

16 Days (15 Nights) Fort Lauderdale to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 23 April 2027
Visit: USA, Bahamas, Morocco, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$821
Oceanview
$912
Balcony
$1,554
Suite
$3,989
From
US$821
Save 421
Per Person
View Trip
15 Day Spain & Morocco Transatlantic with Virgin Voyages
Cruise
 (5)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departure: 02 May 2027
Visit: USA, Spain, Morocco
Inside
$1,475
Oceanview
$1,526
Balcony
$1,666
Suite
$5,530
From
US$1,475
Per Person
View Trip
17 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

17 Days (16 Nights) New York to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Escape
Departure: 26 September 2026
Visit: USA, Canada, Portugal, Gibraltar, Spain
Inside
$2,269
Oceanview
$2,589
Balcony
$2,799
Suite
$3,019
From
US$2,269
Per Person
View Trip
13 Day Transatlantic Repositioning Cruise From Miami To Barcelona with Norwegian Cruise Line
Cruise
 (1)

13 Days (12 Nights) Miami to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 23 May 2027
Visit: USA, Portugal, Spain
Inside
$1,599
Oceanview
$1,929
Balcony
$2,009
Suite
$3,149
From
US$1,599
Per Person
View Trip
15 Day South Beach To Sant Sebasti with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 10 March 2028
Visit: USA, Bermuda, Portugal, Gibraltar, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,999
Oceanview
$3,399
Balcony
$4,599
Suite
$6,399
From
US$2,999
Save 2,999
Per Person
View Trip
15 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

15 Days (14 Nights) Philadelphia to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Pearl
Departure: 09 April 2028
Visit: USA, Portugal, Spain, France
Inside
$1,569
Oceanview
$1,719
Balcony
$2,569
Suite
$2,919
From
US$1,569
Per Person
View Trip
15 Day Spain & Gibraltar Transatlantic with Royal Caribbean
Cruise
 (1)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Royal Caribbean
Ship: Rhapsody of the Seas
Departure: 19 April 2027
Visit: USA, Bahamas, Gibraltar, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$858
Oceanview
$858
Balcony
$1,480
Suite
$2,415
From
US$858
Save 433
Per Person
View Trip
15 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

15 Days (14 Nights) Orlando to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 18 April 2027
Visit: USA, Portugal, Spain
Inside
$1,379
Oceanview
-
Balcony
$2,139
Suite
$2,279
From
US$1,379
Per Person
View Trip
17 Day A Journey Through Vibrant Cultures Across The Atlantic & The Mediterranean with Explora Journeys
Cruise
 (1)

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 19 March 2028
Visit: USA, Puerto Rico, Antigua and Barbuda, Portugal, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$8,575
From
US$8,575
Per Person
View Trip
15 Day Transatlantic Miami to Morocco & Spain with Virgin Voyages
Cruise
 (1)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 24 April 2027
Visit: USA, Spain, Morocco
Inside
$1,386
Oceanview
$1,937
Balcony
$1,666
Suite
$5,586
From
US$1,386
Per Person
View Trip
16 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Star
Departure: 01 March 2027
Visit: USA, Dominican Republic, Puerto Rico, Portugal, Spain
Inside
$1,979
Oceanview
$2,229
Balcony
$3,279
Suite
$3,929
From
US$1,979
Per Person
View Trip
14 Day Atlantic Ocean Passage with Viking Cruises
Cruise
 (8)

14 Days (13 Nights) Fort Lauderdale to Barcelona
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Jan 2027 to Feb 2028
Visit: USA, Sint Maarten, Portugal, Spain
Viking $799 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,199
Suite
$5,799
From
US$3,199
Save 450
Per Person
View Trip
20 Day Transatlantic Combination Cruise: Miami To Barcelona with Azamara Cruises
Cruise
 (5)

20 Days (19 Nights) Miami to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 02 April 2028
Visit: USA, Bermuda, Portugal, Spain, Gibraltar
Azamara Always Included
Inside
$3,539
Oceanview
$3,869
Balcony
$4,849
Suite
$6,989
From
US$3,539
Per Person
View Trip
15 Day Gilded Crossing with Regent Seven Seas
Cruise

15 Days (14 Nights) New York to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 27 April 2027
Visit: USA, Bermuda, Portugal, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$14,049
From
US$14,049
Save 14,049
Per Person
View Trip
15 Day Exuberant Bermuda & Azores with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 18 March 2028
Visit: USA, Bermuda, Portugal, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,999
Suite
$11,199
From
US$9,999
Save 9,999
Per Person
View Trip
28 Day Springtime Atlantic Crossing with Regent Seven Seas
Cruise

28 Days (27 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 20 March 2028
Visit: USA, Dominican Republic, Puerto Rico, Saint Barthelemy (+8 more), Dominica, Guadeloupe, Saint Kitts and Nevis, Virgin Islands, Bahamas, Portugal, Spain, Morocco
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$19,299
Suite
$21,299
From
US$19,299
Save 19,299
Per Person
View Trip
23 Day Caribbean And Antilles with MSC Cruises
Cruise

23 Days (22 Nights) Miami to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 19 March 2028
Visit: USA, Turks and Caicos Islands, Bahamas, Saint Martin, Portugal, Spain, France
Inside
$2,035
Oceanview
$2,405
Balcony
$2,965
Suite
$5,945
From
US$2,035
Per Person
View Trip
16 Day Spain & Portugal Transatlantic with Celebrity Cruises
Cruise

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departure: 11 April 2027
Visit: USA, Portugal, Spain, Morocco
Exclusive Savings
Inside
$1,958
Oceanview
$2,206
Balcony
$2,962
Suite
$17,360
From
US$1,958
Save 1,090
Per Person
View Trip
16 Day Elegance Of The Atlantic with Regent Seven Seas
Cruise

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 01 April 2028
Visit: USA, Bahamas, Portugal, Spain, Morocco
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,449
Suite
$12,549
From
US$11,449
Save 11,449
Per Person
View Trip
17 Day A Grand Journey From Atlantic Exploration To Mediterranean Delights with Explora Journeys
Cruise

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 08 March 2027
Visit: USA, Puerto Rico, Saint Martin, Portugal, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$7,620
From
US$7,620
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise

15 Days (14 Nights) Miami to Malaga
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 10 April 2027
Visit: USA, Saint Martin, Portugal, Spain
Inside
$1,198
Oceanview
$1,307
Balcony
$1,681
Suite
-
From
US$1,198
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) Miami to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 25 March 2028
Visit: USA, Saint Martin, Portugal, Spain, France
Inside
$1,393
Oceanview
$1,803
Balcony
$2,203
Suite
$3,563
From
US$1,393
Per Person
View Trip
18 Day Spain & Morocco Transatlantic with Royal Caribbean
Cruise

18 Days (17 Nights) New Orleans to Barcelona
Cruise Line: Royal Caribbean
Ship: Mariner of the Seas
Departure: 24 April 2027
Visit: USA, Morocco, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$942
Oceanview
$1,342
Balcony
$1,991
Suite
$3,621
From
US$942
Save 483
Per Person
View Trip
17 Day Brilliant Bermuda & Iberia with Oceania Cruises
Cruise

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 31 March 2027
Visit: USA, Bermuda, Portugal, Spain, Gibraltar
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,149
Suite
$8,899
From
US$5,149
Save 5,149
Per Person
View Trip
15 Day Transatlantic Aspirations with Oceania Cruises
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 18 March 2028
Visit: USA, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,149
Suite
$6,599
From
US$5,149
Save 5,149
Per Person
View Trip
15 Day Spain & Portugal Transatlantic with Royal Caribbean
Cruise

15 Days (14 Nights) Orlando to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 26 April 2027
Visit: USA, Portugal, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$740
Oceanview
$920
Balcony
$1,322
Suite
$2,578
From
US$740
Save 395
Per Person
View Trip
24 Day A Grand Journey Into Island Whispers & Beauty-Rich Shores with Explora Journeys
Cruise

24 Days (23 Nights) San Juan to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 01 March 2027
Visit: Puerto Rico, Antigua and Barbuda, Anguilla, Virgin Islands (+5 more), Turks and Caicos Islands, USA, Saint Martin, Portugal, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$12,530
From
US$12,530
Per Person
View Trip
15 Day The Sea To Seville with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 22 March 2029
Visit: USA, Bahamas, Portugal, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,599
Suite
$13,149
From
US$11,599
Save 11,599
Per Person
View Trip
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