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Cruises from USA to Spain

Are you looking for a cruise from USA to Spain? April is the most popular month to cruise between USA and Spain and there are 41 departures available from eleven of the world's leading cruise lines.
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82 Days
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39 Cruises (41 Cruise Departures)
15 Day Transatlantic Miami to Morocco & Spain with Virgin Voyages
Cruise
 (1)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 24 April 2027
Visit: USA, Spain, Morocco
With Love From the World
Inside
$1,386
Oceanview
$1,526
Balcony
$1,666
Suite
$6,510
From
US$1,386
Per Person
View Trip
15 Day Bermuda & Iberia with Oceania Cruises
Cruise
 (3)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 April 2026
Visit: USA, Bermuda, Portugal, Gibraltar, Spain
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$3,092
Oceanview
-
Balcony
$3,706
Suite
-
From
US$3,092
Save 3,206
Per Person
View Trip
15 Day Spain & Morocco Transatlantic with Virgin Voyages
Cruise
 (5)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departure: 02 May 2027
Visit: USA, Spain, Morocco
With Love From the World
Inside
$1,386
Oceanview
$1,526
Balcony
$1,875
Suite
$5,740
From
US$1,386
Per Person
View Trip
15 Day Cultural Crossing With Morocco & Spain with Holland America
Cruise
 (2)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departure: 09 April 2027
Visit: USA, Morocco, Spain
Book Early & Have It All Fare Option
Inside
$1,044
Oceanview
$1,344
Balcony
$1,524
Suite
$3,680
From
US$1,044
Per Person
View Trip
15 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

15 Days (14 Nights) Philadelphia to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Pearl
Departure: 09 April 2028
Visit: USA, Portugal, Spain, France
Inside
$1,569
Oceanview
$1,719
Balcony
$2,502
Suite
$2,841
From
US$1,569
Per Person
View Trip
15 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

15 Days (14 Nights) Orlando to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 18 April 2027
Visit: USA, Portugal, Spain
Inside
$1,419
Oceanview
-
Balcony
$2,238
Suite
$2,422
From
US$1,419
Per Person
View Trip
15 Day Spanish Passage with Princess
Cruise
 (6)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departure: 28 March 2027
Visit: USA, Spain
Princess Standard
Sanctuary Collection
Inside
$908
Oceanview
$1,149
Balcony
$1,629
Suite
$2,019
From
US$908
Per Person
View Trip
24 Day A Grand Journey Into Island Whispers & Beauty-Rich Shores with Explora Journeys
Cruise

24 Days (23 Nights) San Juan to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 01 March 2027
Visit: Puerto Rico, Antigua and Barbuda, Anguilla, Virgin Islands (+5 more), Turks and Caicos Islands, USA, Saint Martin, Portugal, Spain
A Suite Invitation
Inside
-
Oceanview
-
Balcony
$11,735
Suite
$13,235
From
US$11,735
Per Person
View Trip
13 Day Transatlantic Repositioning Cruise From Miami To Barcelona with Norwegian Cruise Line
Cruise
 (1)

13 Days (12 Nights) Miami to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 23 May 2027
Visit: USA, Portugal, Spain
Inside
$1,509
Oceanview
$1,809
Balcony
$1,929
Suite
$2,860
From
US$1,509
Per Person
View Trip
15 Day Transatlantic to Spain & Morocco with Virgin Voyages
Cruise
 (1)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 26 April 2026
Visit: USA, Spain, Morocco
With Love From the World
Inside
$1,386
Oceanview
$1,526
Balcony
$1,666
Suite
$4,606
From
US$1,386
Per Person
View Trip
13 Day A Journey From Turquoise Shores To Volcanic Isles with Explora Journeys
Cruise

13 Days (12 Nights) Miami to Lanzarote
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 09 March 2026
Visit: USA, Puerto Rico, Saint Martin, Spain
A Suite Invitation
Inside
-
Oceanview
-
Balcony
$5,180
Suite
$5,845
From
US$5,180
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) New York to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 19 April 2026
Visit: USA, Canada, Portugal, Spain, France
Grand Voyages Sale
Inside
$810
Oceanview
$1,040
Balcony
$1,203
Suite
$7,095
From
US$810
Per Person
View Trip
15 Day South Beach To Sant Sebasti with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 10 March 2028
Visit: USA, Bermuda, Portugal, Gibraltar, Spain
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$2,942
Oceanview
$3,330
Balcony
$4,494
Suite
$6,240
From
US$2,942
Save 3,056
Per Person
View Trip
28 Day Springtime Atlantic Crossing with Regent Seven Seas
Cruise

28 Days (27 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 20 March 2028
Visit: USA, Dominican Republic, Puerto Rico, Saint Barthelemy (+8 more), Dominica, Guadeloupe, Saint Kitts and Nevis, Virgin Islands, Bahamas, Portugal, Spain, Morocco
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$14,651
Suite
$16,611
From
US$14,651
Save 24,147
Per Person
View Trip
16 Day Spain & Morocco Transatlantic with Royal Caribbean
Cruise
 (2)

16 Days (15 Nights) Fort Lauderdale to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 23 April 2027
Visit: USA, Bahamas, Morocco, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$1,181
Oceanview
$1,372
Balcony
$1,707
Suite
$3,154
From
US$1,181
Save 575
Per Person
View Trip
15 Day Transatlantic Aspirations with Oceania Cruises
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 18 March 2028
Visit: USA, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,027
Suite
$6,433
From
US$5,027
Save 5,271
Per Person
View Trip
15 Day Spain & Portugal Transatlantic with Royal Caribbean
Cruise

15 Days (14 Nights) Orlando to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 26 April 2027
Visit: USA, Portugal, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$1,000
Oceanview
$1,300
Balcony
$1,682
Suite
$2,677
From
US$1,000
Save 507
Per Person
View Trip
15 Day New York Transatlantic to Spain with Virgin Voyages
Cruise
 (1)

15 Days (14 Nights) New York to Barcelona
Cruise Line: Virgin Voyages
Ship: Valiant Lady
Departure: 25 April 2026
Visit: USA, Portugal, Morocco, Spain
With Love From the World
Up to $300 Onboard Credit
Inside
$1,878
Oceanview
$1,666
Balcony
$1,806
Suite
$5,586
From
US$1,666
Per Person
View Trip
15 Day Spain & Gibraltar Transatlantic with Royal Caribbean
Cruise
 (1)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Royal Caribbean
Ship: Rhapsody of the Seas
Departure: 19 April 2027
Visit: USA, Bahamas, Gibraltar, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$827
Oceanview
$998
Balcony
$1,661
Suite
$2,335
From
US$827
Save 421
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise

15 Days (14 Nights) Miami to Malaga
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 10 April 2027
Visit: USA, Saint Martin, Portugal, Spain
Bonus Onboard Credit
Inside
$1,208
Oceanview
$1,408
Balcony
$1,638
Suite
-
From
US$1,208
Per Person
View Trip
24 Day Across The Atlantic with Oceania Cruises
Cruise
 (3)

24 Days (23 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 25 March 2028
Visit: USA, Bermuda, Portugal, Spain (+4 more), France, Italy, Corsica, Monaco
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$5,343
Oceanview
$6,653
Balcony
$8,011
Suite
$11,115
From
US$5,343
Save 5,555
Per Person
View Trip
14 Day Atlantic Ocean Passage with Viking Cruises
Cruise
 (8)

14 Days (13 Nights) Fort Lauderdale to Barcelona
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Feb 2026 to Feb 2028
Visit: USA, Sint Maarten, Portugal, Spain
Viking $799 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,099
Suite
$5,499
From
US$3,099
Save 100
Per Person
View Trip
17 Day A Grand Journey From Miami To Barcelona with Explora Journeys
Cruise
 (1)

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 09 April 2026
Visit: USA, Bermuda, Portugal, Spain
A Suite Invitation
Inside
-
Oceanview
-
Balcony
$7,310
Suite
$8,250
From
US$7,310
Per Person
View Trip
16 Day Spain & Portugal Transatlantic with Celebrity Cruises
Cruise

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departure: 11 April 2027
Visit: USA, Portugal, Spain, Morocco
Exclusive Savings
Inside
$2,172
Oceanview
$2,460
Balcony
$2,825
Suite
$11,804
From
US$2,172
Save 1,219
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise

18 Days (17 Nights) Miami to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 10 April 2027
Visit: USA, Saint Martin, Portugal, Spain, France
Bonus Onboard Credit
Inside
$1,434
Oceanview
$1,674
Balcony
$1,934
Suite
$4,702
From
US$1,434
Per Person
View Trip
15 Day Spain & Portugal Transatlantic with Royal Caribbean
Cruise

15 Days (14 Nights) Orlando to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 23 April 2026
Visit: USA, Portugal, Spain
Exclusive Savings
Inside
$1,339
Oceanview
-
Balcony
$2,549
Suite
-
From
US$1,339
Save 631
Per Person
View Trip
15 Day Exuberant Bermuda & Azores with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 18 March 2028
Visit: USA, Bermuda, Portugal, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,394
Suite
$7,864
From
US$6,394
Save 13,604
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise

20 Days (19 Nights) Miami to Palma de Mallorca
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 19 April 2026
Visit: USA, Saint Martin, Portugal, Spain, France, Italy
Bonus Onboard Credit
Inside
$1,119
Oceanview
-
Balcony
$1,806
Suite
$3,526
From
US$1,119
Per Person
View Trip
17 Day A Journey Through Vibrant Cultures Across The Atlantic & The Mediterranean with Explora Journeys
Cruise
 (1)

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 19 March 2028
Visit: USA, Puerto Rico, Antigua and Barbuda, Portugal, Spain
A Suite Invitation
Inside
-
Oceanview
-
Balcony
$8,340
Suite
$9,405
From
US$8,340
Per Person
View Trip
29 Day Splendor Across The Seas with Regent Seven Seas
Cruise

29 Days (28 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 13 March 2026
Visit: USA, Bermuda, Portugal, Spain, Morocco, Italy, France
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$20,086
Suite
$21,262
From
US$20,086
Save 32,612
Per Person
View Trip
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