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Cruises from USA to Spain

Are you looking for a cruise from USA to Spain? April is the most popular month to cruise between USA and Spain and there are 46 departures available from eleven of the world's leading cruise lines.
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45 Cruises (46 Cruise Departures)
24 Day A Grand Journey Into Island Whispers & Beauty-Rich Shores with Explora Journeys
Cruise

24 Days (23 Nights) San Juan to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 01 March 2027
Visit: Puerto Rico, Antigua and Barbuda, Anguilla, Virgin Islands (+5 more), Turks and Caicos Islands, USA, Saint Martin, Portugal, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$10,955
From
US$10,955
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

20 Days (19 Nights) Miami to Palma de Mallorca
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 19 April 2026
Visit: USA, Saint Martin, Portugal, Spain, France, Italy
Drinks & WiFi Package
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$6,436
From
US$6,436
Save 183
Per Person
View Trip
14 Day Atlantic Ocean Passage with Viking Cruises
Cruise
 (8)

14 Days (13 Nights) Fort Lauderdale to Barcelona
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Jan 2027 to Feb 2028
Visit: USA, Sint Maarten, Portugal, Spain
Viking $799 Air Deal
Inside
-
Oceanview
-
Balcony
$2,999
Suite
$5,499
From
US$2,999
Per Person
View Trip
15 Day Exuberant Bermuda & Azores with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 18 March 2028
Visit: USA, Bermuda, Portugal, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,824
Suite
$11,294
From
US$9,824
Save 10,174
Per Person
View Trip
16 Day Spain & Portugal Transatlantic with Celebrity Cruises
Cruise

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departure: 11 April 2027
Visit: USA, Portugal, Spain, Morocco
Exclusive Savings
Inside
$1,980
Oceanview
$2,364
Balcony
$2,593
Suite
$6,605
From
US$1,980
Save 1,223
Per Person
View Trip
17 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

17 Days (16 Nights) New York to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Escape
Departure: 26 September 2026
Visit: USA, Canada, Portugal, Gibraltar, Spain
Exclusive Savings
Inside
$2,453
Oceanview
$2,870
Balcony
$3,035
Suite
$3,375
From
US$2,453
Save 66
Per Person
View Trip
16 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Pearl
Departure: 11 April 2026
Visit: USA, Portugal, Spain
Inside
$1,069
Oceanview
$1,119
Balcony
$1,249
Suite
$1,359
From
US$1,069
Per Person
View Trip
15 Day Spain & Gibraltar Transatlantic with Royal Caribbean
Cruise
 (1)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Royal Caribbean
Ship: Rhapsody of the Seas
Departure: 19 April 2027
Visit: USA, Bahamas, Gibraltar, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$848
Oceanview
$998
Balcony
$1,730
Suite
$2,450
From
US$848
Save 429
Per Person
View Trip
15 Day Spanish Passage with Princess
Cruise
 (6)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departure: 28 March 2027
Visit: USA, Spain
Princess Standard
Inside
$1,008
Oceanview
$1,029
Balcony
$1,459
Suite
$1,769
From
US$1,008
Per Person
View Trip
15 Day Spain & Morocco Transatlantic with Virgin Voyages
Cruise
 (5)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departure: 02 May 2027
Visit: USA, Spain, Morocco
Limited Time Offer
Inside
$1,386
Oceanview
$1,526
Balcony
$1,806
Suite
$5,740
From
US$1,386
Per Person
View Trip
16 Day Spain & Portugal Transatlantic with Celebrity Cruises
Cruise

16 Days (15 Nights) Fort Lauderdale to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departure: 26 April 2026
Visit: USA, Bermuda, Portugal, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,577
Suite
$12,976
From
US$4,577
Save 3,019
Per Person
View Trip
16 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Star
Departure: 01 March 2027
Visit: USA, Dominican Republic, Puerto Rico, Portugal, Spain
Exclusive Savings
Inside
$2,122
Oceanview
$2,510
Balcony
$3,577
Suite
$4,353
From
US$2,122
Save 57
Per Person
View Trip
15 Day Transatlantic Miami to Morocco & Spain with Virgin Voyages
Cruise
 (1)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 24 April 2027
Visit: USA, Spain, Morocco
Limited Time Offer
Inside
$1,386
Oceanview
$1,526
Balcony
$1,666
Suite
$6,510
From
US$1,386
Per Person
View Trip
16 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 14 April 2026
Visit: USA, Portugal, Spain, France
Inside
$1,139
Oceanview
$1,319
Balcony
$1,309
Suite
$2,178
From
US$1,139
Per Person
View Trip
15 Day Spain & Portugal Transatlantic with Royal Caribbean
Cruise

15 Days (14 Nights) Orlando to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 23 April 2026
Visit: USA, Portugal, Spain
Exclusive Savings
Inside
$1,549
Oceanview
-
Balcony
-
Suite
-
From
US$1,549
Save 721
Per Person
View Trip
15 Day New York Transatlantic to Spain with Virgin Voyages
Cruise
 (1)

15 Days (14 Nights) New York to Barcelona
Cruise Line: Virgin Voyages
Ship: Valiant Lady
Departure: 25 April 2026
Visit: USA, Portugal, Morocco, Spain
Limited Time Offer
Inside
$1,878
Oceanview
$1,666
Balcony
$1,806
Suite
$9,786
From
US$1,666
Per Person
View Trip
15 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

15 Days (14 Nights) Philadelphia to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Pearl
Departure: 09 April 2028
Visit: USA, Portugal, Spain, France
Inside
$1,569
Oceanview
$1,719
Balcony
$2,502
Suite
$2,841
From
US$1,569
Per Person
View Trip
17 Day A Grand Journey From Miami To Barcelona with Explora Journeys
Cruise
 (1)

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 09 April 2026
Visit: USA, Bermuda, Portugal, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$6,540
From
US$6,540
Per Person
View Trip
16 Day Elegance Of The Atlantic with Regent Seven Seas
Cruise

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 01 April 2028
Visit: USA, Bahamas, Portugal, Spain, Morocco
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,389
Suite
$12,516
From
US$11,389
Save 11,809
Per Person
View Trip
15 Day Gilded Crossing with Regent Seven Seas
Cruise

15 Days (14 Nights) New York to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 27 April 2027
Visit: USA, Bermuda, Portugal, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,331
Suite
$12,772
From
US$12,331
Save 12,767
Per Person
View Trip
13 Day Transatlantic Repositioning Cruise From Miami To Barcelona with Norwegian Cruise Line
Cruise
 (1)

13 Days (12 Nights) Miami to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 23 May 2027
Visit: USA, Portugal, Spain
Inside
$1,599
Oceanview
$1,899
Balcony
$1,929
Suite
$2,996
From
US$1,599
Per Person
View Trip
15 Day Bermuda & Iberia with Oceania Cruises
Cruise
 (3)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 April 2026
Visit: USA, Bermuda, Portugal, Gibraltar, Spain
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,304
Suite
-
From
US$4,304
Save 4,494
Per Person
View Trip
15 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

15 Days (14 Nights) Orlando to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 18 April 2027
Visit: USA, Portugal, Spain
Inside
$1,389
Oceanview
-
Balcony
$2,180
Suite
$2,218
From
US$1,389
Per Person
View Trip
14 Day A Journey Of Azure Islands & Volcanic Wonders with Explora Journeys
Cruise
 (1)

14 Days (13 Nights) Miami to Cadiz
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 09 April 2026
Visit: USA, Bermuda, Portugal, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,905
From
US$5,905
Per Person
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

14 Days (13 Nights) Miami to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 09 April 2026
Visit: USA, Virgin Islands, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$3,951
From
US$3,951
Save 110
Per Person
View Trip
24 Day Across The Atlantic with Oceania Cruises
Cruise
 (3)

24 Days (23 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 25 March 2028
Visit: USA, Bermuda, Portugal, Spain (+4 more), France, Italy, Corsica, Monaco
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$5,343
Oceanview
$6,653
Balcony
$8,011
Suite
$11,115
From
US$5,343
Save 5,555
Per Person
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

14 Days (13 Nights) Miami to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 19 April 2026
Visit: USA, Saint Martin, Portugal, Spain
Inside
-
Oceanview
-
Balcony
$849
Suite
$2,425
From
US$849
Per Person
View Trip
16 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise

16 Days (15 Nights) New York to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Gem
Departure: 09 April 2026
Visit: USA, Portugal, Gibraltar, Spain, France
Inside
$1,169
Oceanview
-
Balcony
-
Suite
-
From
US$1,169
Per Person
View Trip
15 Day Transatlantic to Spain & Morocco with Virgin Voyages
Cruise
 (1)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 26 April 2026
Visit: USA, Spain, Morocco
Limited Time Offer
Inside
$1,246
Oceanview
$1,386
Balcony
$1,526
Suite
$3,906
From
US$1,246
Per Person
View Trip
16 Day Spain & Morocco Transatlantic with Royal Caribbean
Cruise
 (2)

16 Days (15 Nights) Fort Lauderdale to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 23 April 2027
Visit: USA, Bahamas, Morocco, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$1,211
Oceanview
$1,321
Balcony
$1,684
Suite
$3,551
From
US$1,211
Save 588
Per Person
View Trip
Results: 1-30 of 45

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