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Cruises from USA to Spain

Are you looking for a cruise from USA to Spain? April is the most popular month to cruise between USA and Spain and there are 40 departures available from eleven of the world's leading cruise lines.
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39 Cruises (40 Cruise Departures)
17 Day A Grand Journey From Miami To Barcelona with Explora Journeys
Cruise
 (1)

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 09 April 2026
Visit: USA, Bermuda, Portugal, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$6,540
From
US$6,540
Per Person
View Trip
15 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

15 Days (14 Nights) Philadelphia to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Pearl
Departure: 09 April 2028
Visit: USA, Portugal, Spain, France
Inside
$1,569
Oceanview
$1,719
Balcony
$2,502
Suite
$2,841
From
US$1,569
Per Person
View Trip
15 Day Spanish Passage with Princess
Cruise
 (6)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departure: 28 March 2027
Visit: USA, Spain
Princess Standard
Sanctuary Collection
Inside
$1,087
Oceanview
$1,169
Balcony
$1,589
Suite
$1,869
From
US$1,087
Per Person
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

14 Days (13 Nights) Miami to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 19 April 2026
Visit: USA, Saint Martin, Portugal, Spain
Inside
-
Oceanview
$698
Balcony
$849
Suite
$2,425
From
US$698
Per Person
View Trip
15 Day Bermuda & Iberia with Oceania Cruises
Cruise
 (3)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 April 2026
Visit: USA, Bermuda, Portugal, Gibraltar, Spain
Your World Inclusions
Upgrade Your Experience
Exclusive Savings
Inside
-
Oceanview
$3,625
Balcony
$3,665
Suite
-
From
US$3,625
Save 3,773
Per Person
View Trip
28 Day Springtime Atlantic Crossing with Regent Seven Seas
Cruise

28 Days (27 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 20 March 2028
Visit: USA, Dominican Republic, Puerto Rico, Saint Barthelemy (+8 more), Dominica, Guadeloupe, Saint Kitts and Nevis, Virgin Islands, Bahamas, Portugal, Spain, Morocco
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$19,061
Suite
$21,021
From
US$19,061
Save 19,737
Per Person
View Trip
15 Day Atlantic Isle Exploration with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 07 April 2026
Visit: USA, Bermuda, Portugal, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,634
Suite
$12,320
From
US$11,634
Save 12,064
Per Person
View Trip
15 Day South Beach To Sant Sebasti with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 10 March 2028
Visit: USA, Bermuda, Portugal, Gibraltar, Spain
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$2,942
Oceanview
$3,330
Balcony
$4,494
Suite
$6,240
From
US$2,942
Save 3,056
Per Person
View Trip
17 Day A Journey Through Vibrant Cultures Across The Atlantic & The Mediterranean with Explora Journeys
Cruise
 (1)

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 19 March 2028
Visit: USA, Puerto Rico, Antigua and Barbuda, Portugal, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$8,340
From
US$8,340
Per Person
View Trip
15 Day Exuberant Bermuda & Azores with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 18 March 2028
Visit: USA, Bermuda, Portugal, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,824
Suite
$11,294
From
US$9,824
Save 10,174
Per Person
View Trip
24 Day Across The Atlantic with Oceania Cruises
Cruise
 (3)

24 Days (23 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 25 March 2028
Visit: USA, Bermuda, Portugal, Spain (+4 more), France, Italy, Corsica, Monaco
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
$5,343
Oceanview
$6,653
Balcony
$8,011
Suite
$11,115
From
US$5,343
Save 5,555
Per Person
View Trip
16 Day Spain & Morocco Transatlantic with Royal Caribbean
Cruise
 (2)

16 Days (15 Nights) Fort Lauderdale to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 23 April 2027
Visit: USA, Bahamas, Morocco, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$1,181
Oceanview
$1,372
Balcony
$1,707
Suite
$3,208
From
US$1,181
Save 575
Per Person
View Trip
15 Day Spain & Morocco Transatlantic with Virgin Voyages
Cruise
 (5)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departure: 02 May 2027
Visit: USA, Spain, Morocco
Limited Time Offer
Inside
$1,386
Oceanview
$1,526
Balcony
$1,806
Suite
$5,740
From
US$1,386
Per Person
View Trip
15 Day Transatlantic Repositioning Cruise with Norwegian Cruise Line
Cruise
 (1)

15 Days (14 Nights) Orlando to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 18 April 2027
Visit: USA, Portugal, Spain
Inside
$1,419
Oceanview
-
Balcony
$2,238
Suite
$2,422
From
US$1,419
Per Person
View Trip
14 Day Atlantic Ocean Passage with Viking Cruises
Cruise
 (8)

14 Days (13 Nights) Fort Lauderdale to Barcelona
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Jan 2027 to Feb 2028
Visit: USA, Sint Maarten, Portugal, Spain
Viking $799 Air Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,099
Suite
$5,499
From
US$3,099
Save 100
Per Person
View Trip
15 Day Transatlantic to Spain & Morocco with Virgin Voyages
Cruise
 (1)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 26 April 2026
Visit: USA, Spain, Morocco
Limited Time Offer
Inside
$1,386
Oceanview
$1,526
Balcony
$1,666
Suite
$4,466
From
US$1,386
Per Person
View Trip
82 Day Grand Arctic Adventure with Regent Seven Seas
Cruise

82 Days (81 Nights) New York to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 29 June 2026
Visit: USA, Canada, Greenland, Iceland (+16 more), Scotland, Ireland, England, Wales, France, Belgium, Holland, Sweden, Denmark, Germany, Latvia, Finland, Estonia, Norway, Portugal, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$97,193
Suite
$104,347
From
US$97,193
Save 100,805
Per Person
View Trip
24 Day A Grand Journey Into Island Whispers & Beauty-Rich Shores with Explora Journeys
Cruise

24 Days (23 Nights) San Juan to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 01 March 2027
Visit: Puerto Rico, Antigua and Barbuda, Anguilla, Virgin Islands (+5 more), Turks and Caicos Islands, USA, Saint Martin, Portugal, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$10,955
From
US$10,955
Per Person
View Trip
13 Day Transatlantic Repositioning Cruise From Miami To Barcelona with Norwegian Cruise Line
Cruise
 (1)

13 Days (12 Nights) Miami to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Viva
Departure: 23 May 2027
Visit: USA, Portugal, Spain
Inside
$1,509
Oceanview
$1,849
Balcony
$1,938
Suite
$2,928
From
US$1,509
Per Person
View Trip
16 Day Elegance Of The Atlantic with Regent Seven Seas
Cruise

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 01 April 2028
Visit: USA, Bahamas, Portugal, Spain, Morocco
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,389
Suite
$12,516
From
US$11,389
Save 11,809
Per Person
View Trip
17 Day Brilliant Bermuda & Iberia with Oceania Cruises
Cruise

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 31 March 2027
Visit: USA, Bermuda, Portugal, Spain, Gibraltar
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,816
Suite
$7,708
From
US$5,816
Save 6,082
Per Person
View Trip
16 Day Spain & Portugal Transatlantic with Celebrity Cruises
Cruise

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departure: 11 April 2027
Visit: USA, Portugal, Spain, Morocco
Exclusive Savings
Inside
$2,108
Oceanview
$2,534
Balcony
$2,943
Suite
$13,189
From
US$2,108
Save 1,220
Per Person
View Trip
15 Day Transatlantic Miami to Morocco & Spain with Virgin Voyages
Cruise
 (1)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 24 April 2027
Visit: USA, Spain, Morocco
Limited Time Offer
Inside
$1,386
Oceanview
$1,526
Balcony
$1,666
Suite
$6,510
From
US$1,386
Per Person
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

14 Days (13 Nights) Miami to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 09 April 2026
Visit: USA, Virgin Islands, Spain
Inside
$477
Oceanview
$571
Balcony
$645
Suite
$2,054
From
US$477
Per Person
View Trip
15 Day Spain & Gibraltar Transatlantic with Royal Caribbean
Cruise
 (1)

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Royal Caribbean
Ship: Rhapsody of the Seas
Departure: 19 April 2027
Visit: USA, Bahamas, Gibraltar, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$827
Oceanview
$998
Balcony
$1,661
Suite
$2,390
From
US$827
Save 421
Per Person
View Trip
16 Day Spain & Portugal Transatlantic with Celebrity Cruises
Cruise

16 Days (15 Nights) Fort Lauderdale to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departure: 26 April 2026
Visit: USA, Bermuda, Portugal, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$27,654
From
US$33,195
Save 12,319
Per Person
View Trip
15 Day New York Transatlantic to Spain with Virgin Voyages
Cruise
 (1)

15 Days (14 Nights) New York to Barcelona
Cruise Line: Virgin Voyages
Ship: Valiant Lady
Departure: 25 April 2026
Visit: USA, Portugal, Morocco, Spain
Limited Time Offer
Inside
-
Oceanview
-
Balcony
$1,806
Suite
$5,586
From
US$1,806
Per Person
View Trip
15 Day Spain & Portugal Transatlantic with Royal Caribbean
Cruise

15 Days (14 Nights) Orlando to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 26 April 2027
Visit: USA, Portugal, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$980
Oceanview
$1,240
Balcony
$1,623
Suite
$2,772
From
US$980
Save 498
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

20 Days (19 Nights) Miami to Palma de Mallorca
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 19 April 2026
Visit: USA, Saint Martin, Portugal, Spain, France, Italy
Inside
$1,119
Oceanview
-
Balcony
$1,586
Suite
$3,526
From
US$1,119
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise

15 Days (14 Nights) Miami to Malaga
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 10 April 2027
Visit: USA, Saint Martin, Portugal, Spain
Inside
$1,208
Oceanview
$1,408
Balcony
$1,638
Suite
-
From
US$1,208
Per Person
View Trip
Results: 1-30 of 39

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