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Cruises from USA to Spain

Are you looking for a cruise from USA to Spain? April is the most popular month to cruise between USA and Spain and there are 33 departures available from eleven of the world's leading cruise lines.
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13 Days
84 Days
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32 Cruises (33 Cruise Departures)
15 Day Spanish Passage with Princess
Cruise
 (3)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Princess
Ship: Majestic Princess
Departure: 18 February 2025
Countries Visited: USA, Portugal, Spain
INSIDE
$1,226
OCEANVIEW
-
BALCONY
$1,514
SUITE
$2,572
From 1,226
View Trip
15 Day Cultural Crossing With Madeira And Morocco with Holland America
Cruise
 (1)

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departure: 19 April 2025
Countries Visited: USA, Bermuda, Portugal, Morocco (+1 more), Spain
Have It All Offer
INSIDE
$2,730
OCEANVIEW
$3,027
BALCONY
$3,473
SUITE
$6,789
From 2,730
View Trip
32 Day Fire, Ice & Greenland Grand Adventure with Princess
Cruise
 (2)

32 Days (31 Nights) New York to Barcelona
Cruise Line: Princess
Ship: Island Princess
Departure: 05 July 2024
Countries Visited: USA, Canada, Greenland, Iceland (+5 more), Scotland, England, Spain, Portugal, Morocco
INSIDE
$7,942
OCEANVIEW
$8,170
BALCONY
$10,318
SUITE
$12,265
From 7,942
View Trip
14 Day Atlantic Ocean Passage with Viking Cruises
Cruise
 (4)

14 Days (13 Nights) Fort Lauderdale to Barcelona
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Mar 2025 to Feb 2026
Countries Visited: USA, Sint Maarten, Portugal, Spain
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$4,945
SUITE
$8,905
Save 1,065
From 4,945
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25 Day Transatlantic Tranquility with Oceania Cruises
Cruise
 (2)

25 Days (24 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 12 April 2025
Countries Visited: USA, Curacao, Aruba, Grenada (+9 more), Barbados, Guadeloupe, Saint Kitts and Nevis, Puerto Rico, Saint Barthelemy, Antigua and Barbuda, Portugal, Morocco, Spain
Exclusive Deal
INSIDE
$9,254
OCEANVIEW
$10,165
BALCONY
$13,065
SUITE
$16,956
Save 2,066
From 9,254
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19 Day MSC Grand Voyages with MSC Cruises
Cruise

19 Days (18 Nights) Miami to Alicante
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 08 November 2024
Countries Visited: USA, Virgin Islands, Antigua and Barbuda, Sint Maarten (+4 more), Martinique, Barbados, Portugal, Spain
Early Booking Offer
INSIDE
$2,212
OCEANVIEW
$2,420
BALCONY
$2,985
SUITE
$6,004
From 2,212
View Trip
14 Day Bermuda & Portugal Transatlantic with Celebrity Cruises
Cruise

14 Days (13 Nights) Fort Lauderdale to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Apex
Departure: 08 March 2025
Countries Visited: USA, Bermuda, Portugal, Spain
Exclusive Offer
INSIDE
$1,791
OCEANVIEW
$1,888
BALCONY
$2,558
SUITE
$7,665
Save 2,778
From 1,791
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20 Day MSC Grand Voyages with MSC Cruises
Cruise

20 Days (19 Nights) Miami to Valencia
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 08 November 2024
Countries Visited: USA, Virgin Islands, Antigua and Barbuda, Sint Maarten (+4 more), Martinique, Barbados, Portugal, Spain
Early Booking Offer
INSIDE
$2,294
OCEANVIEW
$2,591
BALCONY
$2,927
SUITE
$5,462
From 2,294
View Trip
15 Day Spanish Passage with Princess
Cruise

15 Days (14 Nights) Fort Lauderdale to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departure: 22 March 2025
Countries Visited: USA, Spain
INSIDE
$1,879
OCEANVIEW
$2,572
BALCONY
$3,424
SUITE
$4,255
From 1,879
View Trip
29 Day Splendor Across The Seas with Regent Seven Seas
Cruise

29 Days (28 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 13 March 2026
Countries Visited: USA, Bermuda, Portugal, Spain (+3 more), Morocco, Italy, France
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$26,485
SUITE
$30,475
Save 11,835
From 26,485
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15 Day Bermuda & Spain Transatlantic with Celebrity Cruises
Cruise

15 Days (14 Nights) Orlando to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 19 April 2025
Countries Visited: USA, Bermuda, Portugal, Spain
Exclusive Offer
INSIDE
$1,640
OCEANVIEW
$1,881
BALCONY
$2,389
SUITE
$8,471
Save 2,751
From 1,640
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17 Day A Journey From Miami To Barcelona with Explora Journeys
Cruise

17 Days (16 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 02 April 2025
Countries Visited: USA, Bermuda, Portugal, Spain
The Total Luxury Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$9,148
SUITE
$11,157
From 9,148
View Trip
15 Day Royal Bermuda & Regal Spain with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 19 March 2025
Countries Visited: USA, Bahamas, Bermuda, Portugal (+1 more), Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,954
SUITE
$12,726
Save 4,496
From 10,954
View Trip
16 Day Miami to Casablanca & Barcelona with Virgin Voyages
Cruise

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 03 May 2025
Countries Visited: USA, Spain, Morocco
INSIDE
$2,632
OCEANVIEW
$3,199
BALCONY
$3,505
SUITE
$8,563
From 2,632
View Trip
14 Day Spain & Canary Crossing with Royal Caribbean
Cruise

14 Days (13 Nights) Miami to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 28 April 2024
Countries Visited: USA, Spain
Exclusive Deal
INSIDE
$2,468
OCEANVIEW
-
BALCONY
-
SUITE
-
Save 877
From 1,985
View Trip
24 Day MSC Grand Voyages with MSC Cruises
Cruise

24 Days (23 Nights) Miami to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 06 April 2025
Countries Visited: USA, Sint Maarten, Antigua and Barbuda, Barbados (+5 more), Portugal, Spain, Sicily, Italy, France
Early Booking Offer
INSIDE
$3,289
OCEANVIEW
$3,834
BALCONY
$4,467
SUITE
$6,339
From 3,289
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise

21 Days (20 Nights) Miami to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 08 November 2024
Countries Visited: USA, Virgin Islands, Antigua and Barbuda, Sint Maarten (+4 more), Martinique, Barbados, Portugal, Spain
Early Booking Offer
INSIDE
$2,484
OCEANVIEW
$2,722
BALCONY
$3,365
SUITE
$7,196
From 2,484
View Trip
15 Day Atlantic Isle Exploration with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 07 April 2026
Countries Visited: USA, Bermuda, Portugal, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$11,104
SUITE
$12,648
Save 7,046
From 11,104
View Trip
84 Day Grand Arctic Adventure with Regent Seven Seas
Cruise

84 Days (83 Nights) New York to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 02 June 2024
Countries Visited: USA, Canada, Greenland, Iceland (+18 more), Faroe Islands, Scotland, Ireland, England, Wales, France, Belgium, Holland, Denmark, Sweden, Germany, Poland, Lithuania, Finland, Estonia, Norway, Spain, Portugal
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$101,022
SUITE
$107,674
Save 18,618
From 101,022
View Trip
13 Day A Journey From Miami To Lanzarote with Explora Journeys
Cruise

13 Days (12 Nights) Miami to Arrecife
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 31 May 2024
Countries Visited: USA, Saint Barthelemy, Antigua and Barbuda, Spain
Exclusive DealThe Total Luxury Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$5,341
SUITE
$6,207
From 5,341
View Trip
45 Day A Grand Journey Connecting Continents with Explora Journeys
Cruise

45 Days (44 Nights) Vancouver to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 06 May 2024
Countries Visited: Canada, USA, Mexico, Guatemala (+7 more), Costa Rica, Panama, Colombia, Saint Barthelemy, Antigua and Barbuda, Morocco, Spain
The Total Luxury Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$28,156
From 28,156
View Trip
15 Day Bermuda & Iberia with Oceania Cruises
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 April 2026
Countries Visited: USA, Bermuda, Portugal, Gibraltar (+1 more), Spain
Exclusive Deal
INSIDE
$4,839
OCEANVIEW
$5,987
BALCONY
$6,829
SUITE
$9,403
Save 2,031
From 4,839
View Trip
39 Day A Grand Journey From Latin Shores To European Enclaves with Explora Journeys
Cruise

39 Days (38 Nights) Los Angeles to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 12 May 2024
Countries Visited: USA, Mexico, Guatemala, Costa Rica (+6 more), Panama, Colombia, Saint Barthelemy, Antigua and Barbuda, Spain, Morocco
The Total Luxury Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$23,849
From 23,849
View Trip
17 Day Transatlantic Cruise with Royal Caribbean
Cruise

17 Days (16 Nights) Galveston to Barcelona
Cruise Line: Royal Caribbean
Ship: Harmony of the Seas
Departure: 16 March 2026
Countries Visited: USA, Bahamas, Spain
Exclusive Deal
INSIDE
$2,729
OCEANVIEW
$3,289
BALCONY
$3,271
SUITE
-
Save 1,016
From 2,404
View Trip
20 Day A Transatlantic Journey From Miami To Moroccan Fantasies with Explora Journeys
Cruise

20 Days (19 Nights) Miami to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 31 May 2024
Countries Visited: USA, Saint Barthelemy, Antigua and Barbuda, Spain (+1 more), Morocco
Exclusive DealThe Total Luxury Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$10,583
SUITE
$12,291
From 10,583
View Trip
16 Day Azores & Spain Transatlantic with Royal Caribbean
Cruise

16 Days (15 Nights) Galveston to Barcelona
Cruise Line: Royal Caribbean
Ship: Voyager of the Seas
Departure: 01 May 2024
Countries Visited: USA, Bahamas, Portugal, Spain
Exclusive Deal
INSIDE
$2,768
OCEANVIEW
$3,274
BALCONY
-
SUITE
-
From 2,908
View Trip
84 Day Grand Arctic Adventure with Regent Seven Seas
Cruise

84 Days (83 Nights) New York to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 10 July 2025
Countries Visited: USA, Canada, Greenland, Iceland (+18 more), Faroe Islands, Scotland, Northern Ireland, Ireland, Wales, England, France, Belgium, Holland, Denmark, Germany, Poland, Lithuania, Latvia, Sweden, Norway, Spain, Portugal
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$96,144
SUITE
$106,044
Save 29,326
From 96,144
View Trip
13 Day Spain & Azores Transatlantic with Royal Caribbean
Cruise

13 Days (12 Nights) Miami to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 30 April 2025
Countries Visited: USA, Portugal, Spain
Exclusive Deal
INSIDE
$1,473
OCEANVIEW
$1,767
BALCONY
$2,200
SUITE
$3,405
From 1,894
View Trip
13 Day Spain Transatlantic with Royal Caribbean
Cruise

13 Days (12 Nights) Miami to Barcelona
Cruise Line: Royal Caribbean
Ship: Allure of the Seas
Departure: 10 February 2025
Countries Visited: USA, Spain
Exclusive Deal
INSIDE
$1,606
OCEANVIEW
$1,906
BALCONY
$1,964
SUITE
$6,209
Save 964
From 1,680
View Trip
14 Day Spain & Azores Transatlantic with Royal Caribbean
Cruise

14 Days (13 Nights) Orlando to Barcelona
Cruise Line: Royal Caribbean
Ship: Voyager of the Seas
Departure: 03 May 2025
Countries Visited: USA, Portugal, Spain
Exclusive Deal
INSIDE
$1,765
OCEANVIEW
$2,094
BALCONY
$3,059
SUITE
$4,886
Save 692
From 1,570
View Trip
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