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Cruises from USA to Spain

Are you looking for a cruise from USA to Spain? April is the most popular month to cruise between USA and Spain and there are 41 departures available from eleven of the world's leading cruise lines.
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13 Days
82 Days
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39 Cruises (41 Cruise Departures)
15 Day Atlantic Isle Exploration with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 07 April 2026
Visit: USA, Bermuda, Portugal, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,547
Suite
$9,233
From
US$8,547
Save 15,051
Per Person
View Trip
15 Day Gilded Crossing with Regent Seven Seas
Cruise

15 Days (14 Nights) New York to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 27 April 2027
Visit: USA, Bermuda, Portugal, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$9,342
From
US$9,342
Save 16,656
Per Person
View Trip
13 Day A Journey From Turquoise Shores To Volcanic Isles with Explora Journeys
Cruise

13 Days (12 Nights) Miami to Lanzarote
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 09 March 2026
Visit: USA, Puerto Rico, Saint Martin, Spain
A Suite Invitation
Inside
-
Oceanview
-
Balcony
$5,180
Suite
$5,845
From
US$5,180
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise

18 Days (17 Nights) Miami to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 10 April 2027
Visit: USA, Saint Martin, Portugal, Spain, France
Bonus Onboard Credit
Inside
$1,434
Oceanview
$1,674
Balcony
$1,934
Suite
$4,702
From
US$1,434
Per Person
View Trip
29 Day Splendor Across The Seas with Regent Seven Seas
Cruise

29 Days (28 Nights) Miami to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 13 March 2026
Visit: USA, Bermuda, Portugal, Spain, Morocco, Italy, France
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$20,086
Suite
$21,262
From
US$20,086
Save 32,612
Per Person
View Trip
16 Day Spain & Portugal Transatlantic with Celebrity Cruises
Cruise

16 Days (15 Nights) Miami to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departure: 11 April 2027
Visit: USA, Portugal, Spain, Morocco
Exclusive Savings
Inside
$2,172
Oceanview
$2,460
Balcony
$2,825
Suite
$11,804
From
US$2,172
Save 1,219
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise

15 Days (14 Nights) Miami to Malaga
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 10 April 2027
Visit: USA, Saint Martin, Portugal, Spain
Bonus Onboard Credit
Inside
$1,208
Oceanview
$1,408
Balcony
$1,638
Suite
-
From
US$1,208
Per Person
View Trip
15 Day Transatlantic Aspirations with Oceania Cruises
Cruise

15 Days (14 Nights) Miami to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 18 March 2028
Visit: USA, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,027
Suite
$6,433
From
US$5,027
Save 5,271
Per Person
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise

14 Days (13 Nights) Miami to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 19 April 2026
Visit: USA, Saint Martin, Portugal, Spain
Inside
$518
Oceanview
$698
Balcony
$849
Suite
-
From
US$518
Per Person
View Trip
Results: 31-39 of 39

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Cruises from USA to Spain

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