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Antigua and Barbuda Cruises

Are you looking for a cruise to Antigua and Barbuda? Choose from 76 unique cruise itineraries to Antigua and Barbuda, departing from Boston, Bridgetown, Fort Lauderdale, Fort-de-France, La Romana and more. December is the most popular month to cruise to Antigua and Barbuda and we have over 153 departures available from sixteen of the world's leading cruise lines.
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76 Cruises (153 Cruise Departures)
8 Day Eastern Caribbean Holiday with Celebrity Cruises
Cruise

8 Days (7 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Reflection
Departure: 28 December 2026
Visit: USA, Dominican Republic, Virgin Islands, Antigua and Barbuda
Exclusive Savings
Inside
$1,759
Oceanview
$1,886
Balcony
$2,117
Suite
$4,713
From
US$1,759
Save 1,084
Per Person
View Trip
7 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

7 Days (6 Nights) San Juan to San Juan
Cruise Line: Royal Caribbean
Ship: Rhapsody of the Seas
Departure: 18 December 2027
Visit: Puerto Rico, Virgin Islands, Saint Kitts and Nevis, Antigua and Barbuda
Bonus Onboard Credit
Exclusive Savings
Inside
$794
Oceanview
$854
Balcony
$1,374
Suite
$1,559
From
US$794
Save 445
Per Person
View Trip
12 Day Wellness Retreat: Spain to Antigua with Scenic
New ReleaseCruise

12 Days (11 Nights) Tenerife to Saint John's
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 04 October 2027
Visit: Spain, Saint Martin, Saint Barthelemy, Antigua and Barbuda
Select Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,949
Suite
$10,018
From
US$6,949
Save 696
Per Person
View Trip
8 Day St. Thomas & Antigua Cruise with Celebrity Cruises
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Celebrity Cruises
Ship: Celebrity Xcel
Departures: Dec 2026 to Mar 2027
Visit: USA, Bahamas, Virgin Islands, Antigua and Barbuda
Exclusive Savings
Inside
$1,067
Oceanview
$1,136
Balcony
$1,376
Suite
$3,616
From
US$1,067
Save 1,079
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 05 December 2027
Visit: USA, Antigua and Barbuda, Virgin Islands, Dominican Republic
Inside
$659
Oceanview
$809
Balcony
$969
Suite
$1,489
From
US$659
Per Person
View Trip
15 Day History On The Horizon with Regent Seven Seas
Cruise

15 Days (14 Nights) Lisbon to New York
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 23 August 2026
Visit: Portugal, Antigua and Barbuda, Canada, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,049
Suite
$14,099
From
US$13,049
Save 13,049
Per Person
View Trip
4 Day South Caribbean with MSC Cruises
Cruise

4 Days (3 Nights) Fort-de-France to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 12 March 2027
Visit: Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic
Inside
-
Oceanview
$299
Balcony
$539
Suite
$719
From
US$299
Per Person
View Trip
8 Day Caribbean Yachting Discovery with Emerald Cruises
New ReleaseCruise

8 Days (7 Nights) Saint John's to San Juan
Cruise Line: Emerald Cruises
Ship: Emerald Kaia
Departures: Nov 2027 to Mar 2028
Visit: Antigua and Barbuda, Saint Barthelemy, Guadeloupe, Virgin Islands
Preferred Plus Fare + Air Credit
Exclusive Savings
Inside
-
Oceanview
$6,135
Balcony
-
Suite
$7,773
From
US$6,135
Save 640
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Apr 2027 to Nov 2027
Visit: Martinique, Antigua and Barbuda, Dominican Republic, Barbados
Inside
$629
Oceanview
$789
Balcony
$1,229
Suite
$1,869
From
US$629
Per Person
View Trip
8 Day Southern Caribbean Holiday with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) San Juan to San Juan
Cruise Line: Royal Caribbean
Ship: Rhapsody of the Seas
Departure: 26 December 2026
Visit: Puerto Rico, Virgin Islands, Saint Martin, Antigua and Barbuda, Saint Kitts and Nevis
Exclusive Savings
Inside
$1,389
Oceanview
$1,589
Balcony
$2,699
Suite
$2,812
From
US$1,389
Save 736
Per Person
View Trip
8 Day Southern Caribbean & Aruban Nights with Virgin Voyages
Cruise
 (1)

8 Days (7 Nights) San Juan to San Juan
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departures: Jan 2028 to Mar 2028
Visit: Puerto Rico, Aruba, Saint Lucia, Antigua and Barbuda, Saint Martin
Limited Time Offer
Inside
$763
Oceanview
$903
Balcony
$1,253
Suite
$3,850
From
US$763
Per Person
View Trip
8 Day A Journey Across Oceanic Gems & The Unresistible Caribbean Charm with Explora Journeys
Cruise
 (1)

8 Days (7 Nights) Miami to San Juan
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 05 March 2028
Visit: USA, Anguilla, Virgin Islands, Antigua and Barbuda, Puerto Rico
Inside
-
Oceanview
-
Balcony
-
Suite
$3,655
From
US$3,655
Per Person
View Trip
10 Day Antigua, St. Kitts & St. Thomas with Celebrity Cruises
Cruise
 (2)

10 Days (9 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Eclipse
Departure: 19 February 2027
Visit: USA, Antigua and Barbuda, Dominica, Saint Kitts and Nevis, Virgin Islands
Exclusive Savings
Inside
$1,163
Oceanview
$1,253
Balcony
$1,545
Suite
$5,189
From
US$1,163
Save 767
Per Person
View Trip
8 Day Southern Caribbean Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Juan to San Juan
Cruise Line: Royal Caribbean
Ship: Vision of the Seas
Departure: 27 December 2026
Visit: Puerto Rico, Virgin Islands, Antigua and Barbuda, Dominica, Saint Martin
Exclusive Savings
Inside
$1,553
Oceanview
$1,804
Balcony
$2,723
Suite
$2,561
From
US$1,553
Save 806
Per Person
View Trip
8 Day Southern Caribbean & Aruban Nights with Virgin Voyages
Cruise
 (1)

8 Days (7 Nights) San Juan to San Juan
Cruise Line: Virgin Voyages
Ship: Valiant Lady
Departure: 06 February 2027
Visit: Puerto Rico, Aruba, Curacao, Antigua and Barbuda, Saint Martin
Limited Time Offer
Inside
$1,043
Oceanview
$1,253
Balcony
$1,463
Suite
$3,983
From
US$1,043
Per Person
View Trip
7 Day Southern Caribbean Cruise with Virgin Voyages
Cruise
 (1)

7 Days (6 Nights) San Juan to San Juan
Cruise Line: Virgin Voyages
Ship: Valiant Lady
Departure: 14 November 2026
Visit: Puerto Rico, Virgin Islands, Antigua and Barbuda, Saint Lucia, Saint Kitts and Nevis
Limited Time Offer
Inside
$1,014
Oceanview
$1,134
Balcony
$1,314
Suite
$3,294
From
US$1,014
Per Person
View Trip
10 Day Best Of Southern Caribbean with Celebrity Cruises
Cruise
 (2)

10 Days (9 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Eclipse
Departure: 29 January 2028
Visit: USA, Virgin Islands, Antigua and Barbuda, Saint Lucia, Saint Martin
Exclusive Savings
Inside
$1,110
Oceanview
$1,210
Balcony
$1,410
Suite
$4,683
From
US$1,110
Save 683
Per Person
View Trip
5 Day South Caribbean with MSC Cruises
Cruise

5 Days (4 Nights) Bridgetown to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 11 March 2027
Visit: Barbados, Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic
Inside
-
Oceanview
$399
Balcony
-
Suite
-
From
US$399
Per Person
View Trip
8 Day Southern Caribbean & Aruban Nights with Virgin Voyages
Cruise
 (1)

8 Days (7 Nights) San Juan to San Juan
Cruise Line: Virgin Voyages
Ship: Valiant Lady
Departure: 27 March 2027
Visit: Puerto Rico, Curacao, Aruba, Antigua and Barbuda, Saint Martin
Limited Time Offer
Inside
-
Oceanview
-
Balcony
$1,708
Suite
-
From
US$1,708
Per Person
View Trip
7 Day Splendours of the Caribbean with Emerald Cruises
New ReleaseCruise

7 Days (6 Nights) Saint Thomas to San Juan
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 03 January 2027
Visit: Virgin Islands, Saint Kitts and Nevis, Antigua and Barbuda, Saint Barthelemy, Puerto Rico
Preferred Plus Fare + Air Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$5,765
From
US$5,765
Save 940
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) San Juan to San Juan
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 05 April 2026
Visit: Puerto Rico, Virgin Islands, Saint Kitts and Nevis, Antigua and Barbuda, Saint Lucia
Exclusive Savings
Inside
$1,127
Oceanview
-
Balcony
-
Suite
-
From
US$1,691
Save 50
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Dec 2026 to Mar 2027
Visit: Dominican Republic, Barbados, Martinique, Antigua and Barbuda, Virgin Islands
Inside
$709
Oceanview
$919
Balcony
$1,498
Suite
$2,029
From
US$709
Per Person
View Trip
11 Day Caribbean Cruise From Philadelphia To Philadelphia with Norwegian Cruise Line
Cruise
 (1)

11 Days (10 Nights) Philadelphia to Philadelphia
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Pearl
Departure: 13 December 2027
Visit: USA, Dominican Republic, Puerto Rico, Antigua and Barbuda, Saint Martin
Inside
$1,099
Oceanview
$1,349
Balcony
$1,699
Suite
$2,099
From
US$1,099
Per Person
View Trip
8 Day Southern Caribbean Holiday with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) San Juan to San Juan
Cruise Line: Royal Caribbean
Ship: Rhapsody of the Seas
Departure: 24 December 2027
Visit: Puerto Rico, Virgin Islands, Antigua and Barbuda, Saint Martin, Saint Kitts and Nevis
Bonus Onboard Credit
Exclusive Savings
Inside
$1,052
Oceanview
$1,122
Balcony
$1,902
Suite
$2,162
From
US$1,052
Save 546
Per Person
View Trip
7 Day Southern Caribbean Cruise with Virgin Voyages
Cruise
 (1)

7 Days (6 Nights) San Juan to San Juan
Cruise Line: Virgin Voyages
Ship: Valiant Lady
Departures: Jan 2027 to Mar 2027
Visit: Puerto Rico, Virgin Islands, Saint Kitts and Nevis, Antigua and Barbuda, Saint Lucia
Limited Time Offer
Inside
$834
Oceanview
$1,014
Balcony
$1,194
Suite
$3,414
From
US$834
Per Person
View Trip
8 Day Wonders of the Caribbean with Ponant
Cruise
 (1)

8 Days (7 Nights) Fort-de-France to Fort-de-France
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 10 February 2027
Visit: Martinique, Antigua and Barbuda, Virgin Islands, Saint Kitts and Nevis, Guadeloupe
Inside
-
Oceanview
-
Balcony
$5,060
Suite
$7,560
From
US$5,060
Per Person
View Trip
12 Day Eastern Caribbean with Cunard
Cruise
 (6)

12 Days (11 Nights) New York to New York
Cruise Line: Cunard
Ship: Queen Mary 2
Departure: 17 November 2026
Visit: USA, Virgin Islands, Saint Kitts and Nevis, Antigua and Barbuda, Saint Martin
Bonus Onboard Credit
Inside
$1,299
Oceanview
$1,579
Balcony
$1,599
Suite
$4,999
From
US$1,299
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) San Juan to San Juan
Cruise Line: Royal Caribbean
Ship: Rhapsody of the Seas
Departure: 02 May 2026
Visit: Puerto Rico, Virgin Islands, Antigua and Barbuda, Saint Martin, Dominica
Exclusive Savings
Inside
$989
Oceanview
$1,003
Balcony
$1,467
Suite
-
From
US$989
Save 560
Per Person
View Trip
8 Day West Indies Island Hopping with Emerald Cruises
New ReleaseCruise

8 Days (7 Nights) San Juan to San Juan
Cruise Line: Emerald Cruises
Ship: Emerald Kaia
Departure: 27 December 2027
Visit: Puerto Rico, Virgin Islands, Saint Martin, Antigua and Barbuda, Saint Kitts and Nevis
Preferred Plus Fare + Air Credit
Exclusive Savings
Inside
-
Oceanview
$6,501
Balcony
-
Suite
$8,139
From
US$6,501
Save 644
Per Person
View Trip
9 Day Antigua, St. Kitts, & San Juan with Celebrity Cruises
Cruise
 (2)

9 Days (8 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Eclipse
Departure: 11 April 2026
Visit: USA, Saint Kitts and Nevis, Antigua and Barbuda, Puerto Rico, Dominican Republic
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$2,009
Suite
$9,932
From
US$2,009
Save 1,359
Per Person
View Trip
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