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Antigua and Barbuda Cruises

Are you looking for a cruise to Antigua and Barbuda? Choose from 71 unique cruise itineraries to Antigua and Barbuda, departing from Boston, Bridgetown, Fort Lauderdale, Fort-de-France, La Romana and more. December is the most popular month to cruise to Antigua and Barbuda and we have over 148 departures available from sixteen of the world's leading cruise lines.
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71 Cruises (148 Cruise Departures)
15 Day San Juan to Lisbon with Silversea
Cruise

15 Days (14 Nights) San Juan to Lisbon
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 09 March 2027
Visit: Puerto Rico, Virgin Islands, Antigua and Barbuda, Spain, Portugal
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
$4,700
Balcony
$5,000
Suite
$8,600
From
US$4,700
Save 2,500
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Apr 2027 to Nov 2027
Visit: Martinique, Antigua and Barbuda, Dominican Republic, Barbados
Inside
$629
Oceanview
$789
Balcony
$1,229
Suite
$1,869
From
US$629
Per Person
View Trip
8 Day Southern Caribbean Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Juan to San Juan
Cruise Line: Royal Caribbean
Ship: Vision of the Seas
Departure: 27 December 2026
Visit: Puerto Rico, Virgin Islands, Antigua and Barbuda, Dominica, Saint Martin
Exclusive Savings
Inside
$1,474
Oceanview
$1,754
Balcony
$2,626
Suite
$2,350
From
US$1,474
Save 771
Per Person
View Trip
12 Day Wellness Retreat: Spain to Antigua with Scenic
New ReleaseCruise

12 Days (11 Nights) Tenerife to Saint John's
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 04 October 2027
Visit: Spain, Saint Martin, Saint Barthelemy, Antigua and Barbuda
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,449
Suite
$8,518
From
US$5,449
Save 2,196
Per Person
View Trip
9 Day Caribbean And Antilles with MSC Cruises
Cruise

9 Days (8 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 13 March 2027
Visit: USA, Saint Martin, Antigua and Barbuda, Virgin Islands, Bahamas
Inside
$708
Oceanview
$888
Balcony
$1,038
Suite
$2,958
From
US$708
Per Person
View Trip
7 Day Splendours of the Caribbean with Emerald Cruises
New ReleaseCruise

7 Days (6 Nights) San Juan to Saint Thomas
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 07 December 2026
Visit: Puerto Rico, Virgin Islands, Saint Kitts and Nevis, Antigua and Barbuda, Saint Barthelemy
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$5,052
From
US$5,052
Save 1,403
Per Person
View Trip
10 Day Boston To San Juan Cruise with Celebrity Cruises
Cruise

10 Days (9 Nights) Boston to San Juan
Cruise Line: Celebrity Cruises
Ship: Celebrity Summit
Departure: 20 October 2027
Visit: USA, Dominican Republic, Virgin Islands, Antigua and Barbuda, Puerto Rico
Exclusive Savings
Inside
$979
Oceanview
$1,029
Balcony
$1,204
Suite
$4,079
From
US$979
Save 551
Per Person
View Trip
9 Day Caribbean And Antilles with MSC Cruises
Cruise

9 Days (8 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 20 November 2027
Visit: USA, Dominican Republic, Virgin Islands, Antigua and Barbuda, Saint Martin
Inside
$878
Oceanview
$1,028
Balcony
$1,198
Suite
$1,768
From
US$878
Per Person
View Trip
10 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

10 Days (9 Nights) Miami to Miami
Cruise Line: Royal Caribbean
Ship: Independence of the Seas
Departure: 10 December 2027
Visit: USA, Antigua and Barbuda, Barbados, Saint Kitts and Nevis, Saint Martin
Bonus Onboard Credit
Exclusive Savings
Inside
$958
Oceanview
$1,079
Balcony
$1,369
Suite
$2,249
From
US$958
Save 495
Per Person
View Trip
15 Day History On The Horizon with Regent Seven Seas
Cruise

15 Days (14 Nights) Lisbon to New York
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 23 August 2026
Visit: Portugal, Antigua and Barbuda, Canada, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,399
Suite
$14,299
From
US$13,399
Save 13,399
Per Person
View Trip
11 Day Lesser Antilles Journey with Regent Seven Seas
Cruise

11 Days (10 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 19 December 2026
Visit: USA, Virgin Islands, Dominica, Antigua and Barbuda, Saint Kitts and Nevis
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,149
Suite
$11,849
From
US$11,149
Save 11,149
Per Person
View Trip
Results: 61-71 of 71

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