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Antigua and Barbuda Cruises Starting In April 2026, 2027 and 2028

If you're looking at joining a cruise to Antigua and Barbuda in April 2026, 2027 or 2028, we have 9 unique cruise itineraries and 57 departures available, operated by three of the world's leading cruise lines departing in April.
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9 Cruises (57 Cruise Departures)
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Apr 2027 to Nov 2027
Visit: Martinique, Antigua and Barbuda, Dominican Republic, Barbados
Bonus Onboard Credit
Inside
$629
Oceanview
$789
Balcony
$1,229
Suite
$1,869
From
US$629
Per Person
View Trip
10 Day Antigua, St. Lucia & St. Thomas with Celebrity Cruises
Cruise
 (2)

10 Days (9 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Eclipse
Departures: Nov 2026 to Apr 2027
Visit: USA, Antigua and Barbuda, Saint Lucia, Saint Kitts and Nevis, Virgin Islands
Exclusive Savings
Inside
$934
Oceanview
$1,314
Balcony
$1,321
Suite
$4,128
From
US$934
Save 946
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Apr 2027 to Nov 2027
Visit: Dominican Republic, Virgin Islands, Saint Martin, Martinique, Antigua and Barbuda
Bonus Onboard Credit
Inside
$629
Oceanview
$789
Balcony
$1,229
Suite
$1,869
From
US$629
Per Person
View Trip
7 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

7 Days (6 Nights) San Juan to San Juan
Cruise Line: Royal Caribbean
Ship: Jewel of the Seas
Departure: 25 April 2026
Visit: Puerto Rico, Virgin Islands, Antigua and Barbuda, Saint Lucia, Saint Kitts and Nevis
Exclusive Savings
Inside
$874
Oceanview
$874
Balcony
$1,054
Suite
-
From
US$874
Save 530
Per Person
View Trip
10 Day Best Of Southern Caribbean with Celebrity Cruises
Cruise
 (2)

10 Days (9 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Eclipse
Departures: Dec 2027 to Apr 2028
Visit: USA, Saint Martin, Antigua and Barbuda, Saint Lucia, Saint Kitts and Nevis
Exclusive Savings
Inside
$981
Oceanview
$1,081
Balcony
$1,281
Suite
$4,472
From
US$981
Save 792
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) San Juan to San Juan
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 05 April 2026
Visit: Puerto Rico, Virgin Islands, Saint Kitts and Nevis, Antigua and Barbuda, Saint Lucia
Exclusive Savings
Inside
$634
Oceanview
$664
Balcony
-
Suite
$1,775
From
US$634
Save 403
Per Person
View Trip
8 Day Southern Caribbean Cruise with Royal Caribbean
Cruise
 (1)

8 Days (7 Nights) San Juan to San Juan
Cruise Line: Royal Caribbean
Ship: Rhapsody of the Seas
Departures: Feb 2028 to Apr 2028
Visit: Puerto Rico, Virgin Islands, Saint Martin, Antigua and Barbuda, Saint Kitts and Nevis
Bonus Onboard Credit
Exclusive Savings
Inside
$779
Oceanview
$840
Balcony
$1,499
Suite
$1,629
From
US$779
Save 495
Per Person
View Trip
9 Day Antigua, St. Kitts, & San Juan with Celebrity Cruises
Cruise
 (2)

9 Days (8 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Eclipse
Departures: Mar 2026 to Apr 2026
Visit: USA, Saint Kitts and Nevis, Antigua and Barbuda, Puerto Rico, Dominican Republic
Exclusive Savings
Inside
$788
Oceanview
$948
Balcony
$1,323
Suite
$4,020
From
US$788
Save 4,466
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Mar 2027 to Apr 2028
Visit: Dominican Republic, Virgin Islands, Saint Martin, Saint Kitts and Nevis, Antigua and Barbuda
Bonus Onboard Credit
Inside
$649
Oceanview
$799
Balcony
$1,289
Suite
$1,859
From
US$649
Per Person
View Trip
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