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Cruises from San Diego

Choose from 75 unique cruises starting in San Diego, and travelling to Buenos Aires, Fort Lauderdale, London, Melbourne, Miami and more. December and January are the most popular months to join a cruise from San Diego and you can select from 131 departures available from six leading cruise lines.
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91 Days
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75 Cruises (131 Cruise Departures)
7 Day Pacific Coastal Cruise with Holland America
Cruise

7 Days (6 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Eurodam
Departure: 17 April 2028
Visit: USA, Canada
Fare Saver
Exclusive Savings
Inside
$1,293
Oceanview
$1,452
Balcony
$1,907
Suite
$2,600
From
A$1,293
Per Person
View Trip
17 Day Panama Canal with Holland America
Cruise

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Eurodam
Departures: Oct 2026 to Oct 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Flash Deal
Have It All Fare Option
Fare Saver
Exclusive Savings
Inside
$2,767
Oceanview
$2,846
Balcony
$4,420
Suite
$7,866
From
A$2,767
Per Person
View Trip
8 Day Mexican Riviera with Holland America
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zuiderdam
Departure: 16 January 2027
Visit: USA, Mexico
Fare Saver
Exclusive Savings
Inside
$1,309
Oceanview
$1,467
Balcony
$1,923
Suite
$3,685
From
A$1,309
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Mar 2027
Visit: USA, Mexico
Exclusive Savings
Inside
$529
Oceanview
$571
Balcony
$688
Suite
$1,007
From
A$529
Save 339
Per Person
View Trip
8 Day Cabo Overnight, Catalina & Ensenada with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 13 December 2026
Visit: USA, Mexico
Exclusive Savings
Inside
$965
Oceanview
$995
Balcony
$1,172
Suite
$2,204
From
A$965
Save 451
Per Person
View Trip
3 Day Ensenada Cruise with Royal Caribbean
Cruise

3 Days (2 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 October 2026
Visit: USA, Mexico
Exclusive Savings
Inside
$475
Oceanview
$518
Balcony
$661
Suite
$1,148
From
A$475
Save 258
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 27 December 2026
Visit: USA, Mexico
Exclusive Savings
Inside
$1,829
Oceanview
$2,025
Balcony
$2,337
Suite
$4,183
From
A$1,829
Save 960
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 March 2027
Visit: USA, Mexico
Exclusive Savings
Inside
$644
Oceanview
$741
Balcony
$862
Suite
$1,202
From
A$644
Save 319
Per Person
View Trip
16 Day Panama Canal with Holland America
Cruise

16 Days (15 Nights) San Diego to Miami
Cruise Line: Holland America
Ship: Zuiderdam
Departure: 30 January 2027
Visit: USA, Mexico, Guatemala, Panama, Colombia, Bahamas
Fare Saver
Exclusive Savings
Inside
$3,049
Oceanview
$3,197
Balcony
$4,682
Suite
$6,910
From
A$3,049
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visit: USA, Mexico
Exclusive Savings
Inside
$637
Oceanview
$649
Balcony
$739
Suite
$1,105
From
A$637
Save 365
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Feb 2027 to Mar 2027
Visit: USA, Mexico
Exclusive Savings
Inside
$658
Oceanview
$662
Balcony
$789
Suite
$1,130
From
A$658
Save 365
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Dec 2026 to Apr 2027
Visit: USA, Mexico
Exclusive Savings
Inside
$530
Oceanview
$543
Balcony
$667
Suite
$1,013
From
A$530
Save 331
Per Person
View Trip
7 Day Pacific Coastal Cruise with Holland America
Cruise

7 Days (6 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Eurodam
Departure: 17 April 2027
Visit: USA, Canada
Fare Saver
Exclusive Savings
Inside
$1,189
Oceanview
$1,259
Balcony
$1,605
Suite
$2,447
From
A$1,189
Per Person
View Trip
16 Day Panama Canal Eastward Cruise with Royal Caribbean
Cruise

16 Days (15 Nights) San Diego to Tampa
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 October 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia, Cayman Islands
Exclusive Savings
Inside
$3,123
Oceanview
$3,446
Balcony
$5,905
Suite
-
From
A$3,123
Save 1,353
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Dec 2026
Visit: USA, Mexico
Exclusive Savings
Inside
$1,224
Oceanview
$1,360
Balcony
$1,549
Suite
$2,920
From
A$1,224
Save 738
Per Person
View Trip
Results: 61-75 of 75

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Trip Lengths

1 Month 10 Day 2 Week 3 Day 3 Week 4 Week 7 Day

Departure Months

October November December January February March April May

Cities

Amsterdam Anchorage Baltimore Boston Cape Liberty Fort Lauderdale Galveston Honolulu Jacksonville Los Angeles Miami New Orleans New York Orlando Philadelphia San Diego San Francisco San Juan Seattle Seward Tampa Vancouver

Routes

Anchorage to Vancouver Baltimore to Baltimore Barcelona to Fort Lauderdale Barcelona to Miami Boston to Montreal Boston to Quebec City Boston to Boston Bridgetown to Miami Cape Liberty to Cape Liberty Fort Lauderdale to London Fort Lauderdale to Barcelona Fort Lauderdale to Fort Lauderdale Fort Lauderdale to San Diego Fort Lauderdale to Vancouver Galveston to Galveston Honolulu to Tahiti Honolulu to Vancouver Jacksonville to Jacksonville Lisbon to Miami London to Fort Lauderdale London to New York Los Angeles to Miami Los Angeles to Vancouver Los Angeles to Los Angeles Miami to San Juan Miami to Lisbon Miami to Los Angeles Miami to Rome Miami to Bridgetown Miami to Panama City Miami to Barcelona Miami to Miami Miami to London Montreal to Boston Montreal to Miami Montreal to New York New Orleans to New Orleans New York to Montreal New York to New York New York to London Orlando to Orlando Panama City to Miami Philadelphia to Philadelphia Quebec City to Boston Rome to Miami Rome to Fort Lauderdale Rotterdam to Fort Lauderdale San Diego to Fort Lauderdale San Diego to Vancouver San Diego to San Diego San Francisco to San Francisco San Juan to Miami Seattle to Vancouver Seattle to Seattle Seward to Vancouver Sydney to Honolulu Tahiti to Honolulu Tampa to Tampa Toronto to Boston Vancouver to Los Angeles Vancouver to Honolulu Vancouver to Seward Vancouver to Seattle Vancouver to Anchorage Vancouver to San Diego

Country Routes

Argentina to USA Australia to USA Barbados to USA Canada to USA Chile to USA Denmark to USA Dominican Republic to USA England to USA French Polynesia to USA Germany to USA Greece to USA Holland to USA Iceland to USA Italy to USA Japan to USA New Zealand to USA Panama to USA Peru to USA Portugal to USA Puerto Rico to USA Spain to USA USA to Portugal USA to Germany USA to Iceland USA to Puerto Rico USA to Brazil USA to Dominican Republic USA to Argentina USA to Australia USA to Barbados USA to Canada USA to Chile USA to England USA to French Polynesia USA to Holland USA to Italy USA to Japan USA to Panama USA to Peru USA to Spain

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