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Cruises from San Diego

Choose from 90 unique cruises starting in San Diego, and travelling to Buenos Aires, Fort Lauderdale, Guayaquil, Lima, London and more. January is the most popular month to join a cruise from San Diego and you can select from 139 departures available from eight leading cruise lines.
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90 Cruises (139 Departures)
90 Cruises (139 Departures)
Departures
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Duration
3 Days
140 Days
Countries Visited
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Price
$400pp
$122,200pp
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3 Day Ensenada Cruise with Royal Caribbean
Cruise

3 Days (2 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 October 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$460
Oceanview
$474
Balcony
$530
Suite
$911
From (Per Person)
A$460
Save 268
Per Person
View Trip
26 Day San Diego to New York with Crystal Cruises
New ReleaseCruise

26 Days (25 Nights) San Diego to New York
Operator: Crystal
Ship: Crystal Serenity
Departure: 09 August 2027
Visits: USA, Mexico, El Salvador, Nicaragua +5 more, Costa Rica, Panama, Colombia, Jamaica, Cayman Islands
Exclusive Savings
Oceanview
$14,707
Balcony
$18,656
Suite
$19,007
From (Per Person)
A$14,707
Save 4,093
Per Person
View Trip
33 Day San Diego to New York City with Crystal Cruises
New ReleaseCruise

33 Days (32 Nights) San Diego to New York
Operator: Crystal
Ship: Crystal Symphony
Departure: 24 August 2026
Visits: USA, Mexico, El Salvador, Costa Rica +12 more, Ecuador, Panama, Colombia, Dominican Republic, Puerto Rico, Saint Martin, Dominica, Barbados, Saint Lucia, Antigua and Barbuda, Virgin Islands, Turks and Caicos Islands
Exclusive Savings
Oceanview
$21,445
Balcony
$28,465
Suite
$28,660
From (Per Person)
A$21,445
Save 2,955
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Mar 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$522
Oceanview
$555
Balcony
$663
Suite
$991
From (Per Person)
A$522
Save 296
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Dec 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$1,116
Oceanview
$1,238
Balcony
$1,531
Suite
$2,678
From (Per Person)
A$1,116
Save 628
Per Person
View Trip
17 Day Panama Canal with Holland America
Cruise

17 Days (16 Nights) San Diego to Fort Lauderdale
Operator: Holland America
Ship: Eurodam
Departures: Oct 2026 to Oct 2027
Visits: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Have It All Fare Option
Fare Saver
Exclusive Savings
Inside
$2,767
Oceanview
$2,846
Balcony
$4,420
Suite
$9,994
From (Per Person)
A$2,767
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Nov 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$903
Oceanview
$918
Balcony
$1,195
Suite
$3,291
From (Per Person)
A$903
Save 624
Per Person
View Trip
15 Day Mexican Riviera & Baja Peninsula with Holland America
Cruise

15 Days (14 Nights) San Diego to San Diego
Operator: Holland America
Ship: Zuiderdam
Departure: 16 January 2027
Visits: USA, Mexico
Fare Saver
Exclusive Savings
Inside
$2,460
Oceanview
$2,757
Balcony
$3,628
Suite
$6,974
From (Per Person)
A$2,460
Per Person
View Trip
16 Day Panama Canal with Holland America
Cruise

16 Days (15 Nights) San Diego to Miami
Operator: Holland America
Ship: Zuiderdam
Departure: 30 January 2027
Visits: USA, Mexico, Guatemala, Panama, Colombia, Bahamas
Fare Saver
Exclusive Savings
Inside
$3,049
Oceanview
$3,197
Balcony
$4,682
Suite
$6,910
From (Per Person)
A$3,049
Per Person
View Trip
10 Day Roundtrip San Diego with Crystal Cruises
New ReleaseCruise

10 Days (9 Nights) San Diego to San Diego
Operator: Crystal
Ship: Crystal Serenity
Departure: 21 December 2026
Visits: USA, Mexico
Exclusive Savings
Oceanview
$8,017
Balcony
$9,967
Suite
$10,552
From (Per Person)
A$8,017
Save 1,183
Per Person
View Trip
32 Day San Diego to Papeete with Crystal Cruises
New ReleaseCruise

32 Days (31 Nights) San Diego to Tahiti
Operator: Crystal
Ship: Crystal Serenity
Departure: 08 January 2027
Visits: USA, Mexico, El Salvador, Costa Rica +5 more, Ecuador, Peru, Chile, Pitcairn Islands, French Polynesia
Exclusive Savings
Oceanview
$24,827
Balcony
$29,897
Suite
$32,920
From (Per Person)
A$24,827
Save 573
Per Person
View Trip
8 Day Cabo Overnight, Catalina & Ensenada with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 13 December 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$908
Oceanview
$948
Balcony
$1,197
Suite
-
From (Per Person)
A$908
Save 411
Per Person
View Trip
12 Day San Diego to Fuerte Amador with Crystal Cruises
New ReleaseCruise

12 Days (11 Nights) San Diego to Panama City
Operator: Crystal
Ship: Crystal Serenity
Departure: 09 August 2027
Visits: USA, Mexico, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
Oceanview
$6,891
Balcony
$8,997
Suite
$9,173
From (Per Person)
A$6,891
Save 1,809
Per Person
View Trip
8 Day Mexican Riviera From San Diego To San Diego with Norwegian Cruise Line
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Norwegian Cruise Line
Ship: Norwegian Star
Departures: Dec 2026 to Feb 2027
Visits: USA, Mexico
Just Cruise Fare
Exclusive Savings
Inside
$1,244
Oceanview
$1,378
Balcony
$2,019
Suite
$2,302
From (Per Person)
A$1,244
Per Person
View Trip
19 Day Roundtrip San Diego, California with Crystal Cruises
New ReleaseCruise

19 Days (18 Nights) San Diego to San Diego
Operator: Crystal
Ship: Crystal Serenity
Departure: 21 December 2026
Visits: USA, Mexico
Exclusive Savings
Oceanview
$18,765
Balcony
$22,762
Suite
$24,810
From (Per Person)
A$18,765
Save 2,435
Per Person
View Trip
140 Day 2027 World Cruise: San Diego to Vancouver with Crystal Cruises
New ReleaseCruise

140 Days (139 Nights) San Diego to Vancouver
Operator: Crystal
Ship: Crystal Serenity
Departure: 08 January 2027
Visits: USA, Mexico, El Salvador, Costa Rica +24 more, Ecuador, Peru, Chile, Pitcairn Islands, French Polynesia, American Samoa, Samoa, Fiji, Vanuatu, New Caledonia, New Zealand, Australia, Papua New Guinea, Indonesia, Singapore, Thailand, Vietnam, Brunei, Malaysia, Philippines, China, South Korea, Japan, Canada
Exclusive Savings
Oceanview
$119,462
Balcony
$132,625
Suite
$149,590
From (Per Person)
A$119,462
Save 2,738
Per Person
View Trip
13 Day San Diego to Guayaquil (Crystal Wellness Retreat Cruise) with Crystal Cruises
New ReleaseCruise

13 Days (12 Nights) San Diego to Guayaquil
Operator: Crystal
Ship: Crystal Symphony
Departure: 24 August 2026
Visits: USA, Mexico, El Salvador, Costa Rica, Ecuador
Exclusive Savings
Oceanview
$8,707
Balcony
$10,462
Suite
$10,950
From (Per Person)
A$8,707
Save 193
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Dec 2026 to Apr 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$521
Oceanview
$553
Balcony
$633
Suite
$995
From (Per Person)
A$521
Save 331
Per Person
View Trip
19 Day San Diego to Vancouver with Crystal Cruises
New ReleaseCruise

19 Days (18 Nights) San Diego to Vancouver
Operator: Crystal
Ship: Crystal Symphony
Departure: 25 June 2028
Visits: USA, Canada
Exclusive Savings
Oceanview
$12,981
Balcony
$17,368
Suite
$17,456
From (Per Person)
A$12,981
Save 2,519
Per Person
View Trip
8 Day Ensenada, Cabo & Mazatlan with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Feb 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$990
Oceanview
$1,057
Balcony
$1,164
Suite
$2,644
From (Per Person)
A$990
Save 609
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visits: USA, Mexico
Exclusive Savings
Inside
$558
Oceanview
$635
Balcony
$688
Suite
$1,221
From (Per Person)
A$558
Save 346
Per Person
View Trip
10 Day Roundtrip San Diego with Crystal Cruises
New ReleaseCruise

10 Days (9 Nights) San Diego to San Diego
Operator: Crystal
Ship: Crystal Serenity
Departure: 30 December 2026
Visits: USA, Mexico
Exclusive Savings
Oceanview
$8,700
Balcony
$10,845
Suite
$11,722
From (Per Person)
A$8,700
Save 1,200
Per Person
View Trip
8 Day Pacific Coastal Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to Vancouver
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 May 2027
Visits: USA, Canada
Exclusive Savings
Inside
$1,011
Oceanview
$1,018
Balcony
$1,335
Suite
$3,704
From (Per Person)
A$1,011
Save 386
Per Person
View Trip
140 Day San Diego to Vancouver with Crystal Cruises
New ReleaseCruise

140 Days (139 Nights) San Diego to Vancouver
Operator: Crystal
Ship: Crystal Serenity
Departure: 08 January 2027
Visits: USA, Mexico, El Salvador, Costa Rica +24 more, Ecuador, Peru, Chile, Pitcairn Islands, French Polynesia, American Samoa, Samoa, Fiji, Vanuatu, New Caledonia, New Zealand, Australia, Papua New Guinea, Indonesia, Singapore, Thailand, Vietnam, Brunei, Malaysia, Philippines, China, South Korea, Japan, Canada
Exclusive Savings
Oceanview
$119,462
Balcony
$132,625
Suite
$149,590
From (Per Person)
A$119,462
Save 2,738
Per Person
View Trip
16 Day San Diego to Callao (Lima) with Crystal Cruises
New ReleaseCruise

16 Days (15 Nights) San Diego to Lima
Operator: Crystal
Ship: Crystal Serenity
Departure: 08 January 2027
Visits: USA, Mexico, El Salvador, Costa Rica, Ecuador, Peru
Exclusive Savings
Oceanview
$12,225
Balcony
$14,175
Suite
$16,710
From (Per Person)
A$12,225
Save 275
Per Person
View Trip
8 Day Mexican Riviera with Holland America
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Holland America
Ship: Zuiderdam
Departure: 16 January 2027
Visits: USA, Mexico
Fare Saver
Exclusive Savings
Inside
$1,309
Oceanview
$1,467
Balcony
$1,923
Suite
$3,685
From (Per Person)
A$1,309
Per Person
View Trip
7 Day Pacific Coastal Cruise with Holland America
Cruise

7 Days (6 Nights) San Diego to Vancouver
Operator: Holland America
Ship: Eurodam
Departure: 17 April 2027
Visits: USA, Canada
Fare Saver
Exclusive Savings
Inside
$1,189
Oceanview
$1,259
Balcony
$1,605
Suite
$2,447
From (Per Person)
A$1,189
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Operator: Royal Caribbean
Ship: Serenade of the Seas
Departure: 27 December 2026
Visits: USA, Mexico
Exclusive Savings
Inside
$1,569
Oceanview
$1,723
Balcony
$2,012
Suite
$3,562
From (Per Person)
A$1,569
Save 839
Per Person
View Trip
9 Day San Diego to Vancouver with Crystal Cruises
New ReleaseCruise

9 Days (8 Nights) San Diego to Vancouver
Operator: Crystal
Ship: Crystal Symphony
Departure: 25 June 2028
Visits: USA, Canada
Exclusive Savings
Oceanview
$5,877
Balcony
$7,281
Suite
$7,193
From (Per Person)
A$5,877
Save 723
Per Person
View Trip
32 Day San Diego to Papeete with Crystal Cruises
New ReleaseCruise

32 Days (31 Nights) San Diego to Tahiti
Operator: Crystal
Ship: Crystal Serenity
Departure: 08 January 2027
Visits: USA, Mexico, El Salvador, Costa Rica +5 more, Ecuador, Peru, Chile, Pitcairn Islands, French Polynesia
Exclusive Savings
Oceanview
$25,802
Balcony
$30,872
Suite
$33,895
From (Per Person)
A$25,802
Save 598
Per Person
View Trip
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Travel Styles

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Trip Lengths

1 Month 10 Day 2 Week 3 Day 3 Week 4 Week 7 Day

Departure Months

August October November December January February March April May June

Cities

Amsterdam Anchorage Baltimore Boston Cape Liberty Fort Lauderdale Galveston Honolulu Jacksonville Los Angeles Miami New Orleans New York Orlando Philadelphia San Diego San Francisco San Juan Seattle Seward Tampa

Routes

Anchorage to Vancouver Baltimore to Baltimore Barcelona to Fort Lauderdale Barcelona to Miami Boston to Montreal Boston to Quebec City Boston to Boston Bridgetown to Miami Cape Liberty to Cape Liberty Fort Lauderdale to Rome Fort Lauderdale to San Juan Fort Lauderdale to Los Angeles Fort Lauderdale to London Fort Lauderdale to Barcelona Fort Lauderdale to Fort Lauderdale Fort Lauderdale to San Diego Fort Lauderdale to Vancouver Galveston to Galveston Honolulu to Tahiti Honolulu to Vancouver Jacksonville to Jacksonville Lisbon to Miami London to Fort Lauderdale London to New York Los Angeles to Miami Los Angeles to Vancouver Los Angeles to Los Angeles Miami to San Juan Miami to Lisbon Miami to Los Angeles Miami to Rome Miami to Bridgetown Miami to Panama City Miami to Barcelona Miami to Miami Miami to London Montreal to Boston Montreal to Miami Montreal to New York New Orleans to New Orleans New York to Miami New York to Montreal New York to Fort Lauderdale New York to New York New York to Quebec City New York to London Orlando to Orlando Panama City to Miami Philadelphia to Philadelphia Quebec City to Boston Quebec City to New York Reykjavik to New York Rome to Miami Rome to Fort Lauderdale Rotterdam to Fort Lauderdale San Diego to Fort Lauderdale San Diego to Vancouver San Diego to San Diego San Francisco to San Francisco San Juan to Fort Lauderdale San Juan to Miami Seattle to Vancouver Seattle to Seattle Seward to Vancouver Sydney to Honolulu Tahiti to Honolulu Tampa to Tampa Toronto to Boston Vancouver to Los Angeles Vancouver to Honolulu Vancouver to Seward Vancouver to Seattle Vancouver to Anchorage Vancouver to San Diego

Country Routes

Argentina to USA Australia to USA Barbados to USA Brazil to USA Canada to USA Chile to USA Denmark to USA Dominican Republic to USA England to USA French Polynesia to USA Germany to USA Greece to USA Holland to USA Iceland to USA Italy to USA Japan to USA New Zealand to USA Panama to USA Peru to USA Portugal to USA Puerto Rico to USA Spain to USA USA to Portugal USA to Germany USA to Iceland USA to Puerto Rico USA to Brazil USA to Dominican Republic USA to Argentina USA to Australia USA to Barbados USA to Canada USA to Chile USA to England USA to French Polynesia USA to Holland USA to Italy USA to Japan USA to Panama USA to Peru USA to Spain
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