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Panama Canal Eastward Cruise

16 Days San Diego to Tampa
Panama Canal Eastward Cruise
Panama Canal Eastward Cruise
Panama Canal Eastward Cruise
Puerto Quetzal
Puerto Quetzal
Cartagena
Cartagena
San Diego
San Diego
Puntarenas
Puntarenas
Tampa Bay
Tampa Bay
Cruising At Sea
Cruising At Sea
Puerto Vallarta
Puerto Vallarta
Puerto Quetzal
Puerto Quetzal
Tampa Bay
Tampa Bay
Cartagena
Cartagena

Overview

Begin your journey in San Diego and cruise through to Tampa onboard Serenade of the Seas and enjoy exclusive savings and cruise inclusions with Royal Caribbean and Global Journeys.
Our Price From
US$2,375 per person
Price shown based on twin share
Check Availability
Trip Length
Cruise Length

16 Days

Trip Starts
Cruise Starts

San Diego

Trip Ends
Cruise Ends

Tampa

Trip Departures
Cruise Departures
Oct 2027
Cruise Line
Cruise Line
Royal Caribbean
Cruise Shi
Cruise Ship
Serenade of the Seas
Ship Class
Ship Class

Radiance Class

Passengers
Passengers

2,146

Crew
Crew

884

Ship Launch
Launched

2003

Ship Refurbished
Refurbished

2012

Cruise Code
Cruise Code

SR15T253

Itinerary

Departs: 17:00

The Port of San Diego is the fourth largest port in California and is  is located right in downtown San Diego. Major cruise lines depart from the B Street Pier Terminal which is located a 10-minute drive from San Diego International Airport (SAN) and San Diego Station (Amtrak) and is easily accessible from major freeways.  The Embarcadero and nearby areas offer plenty of options for paid parking during your cruise.

Cruise lines embark to destinations such as the Mexican Riviera, Hawaii, the California Coast and the Panama Canal. 


While at sea, take time to recharge before the next adventure. Lounge by the pool, be spoiled at the spa, dine at any of the onboard restaurants or explore the thrills on each deck until we arrive at the next destination. Make the most of your day at sea by enjoying our Wi-Fi, drink and Speciality Dining Packages. These services are available at an additional cost.

Arrives: 08:00 Departs: 17:00

Puerto Vallarta, nestled on Mexico’s Pacific coast, is famed for its vibrant arts scene and stunning natural beauty. The city balances quaint, traditional Mexican charm with the sophistication of a modern resort town. Art enthusiasts are drawn to the numerous galleries along its cobbled streets and the iconic sculptures that line the Malecón, a seaside promenade.

The area is encircled by lush jungles and clear blue waters. Beaches like Playa Los Muertos offer sunbathing and water sports, while nearby, the Vallarta Botanical Gardens provide a tranquil escape with native flora and fauna. For an authentic taste of local life, the Olas Altas Farmers Market showcases crafts, food, and music, enriching any visit to Puerto Vallarta.

While at sea, take time to recharge before the next adventure. Lounge by the pool, be spoiled at the spa, dine at any of the onboard restaurants or explore the thrills on each deck until we arrive at the next destination. Make the most of your day at sea by enjoying our Wi-Fi, drink and Speciality Dining Packages. These services are available at an additional cost.

Arrives: 08:00 Departs: 17:00

Puerto Quetzal, Guatemala’s principal Pacific Ocean port, is a gateway to some of the country’s most captivating attractions. While primarily a launch point for nearby destinations, its proximity to key sites allows visitors to delve into the rich tapestry of local culture and history swiftly. From here, the colonial beauty of Antigua, a UNESCO World Heritage site with its well-preserved Spanish Baroque architecture and stunning volcano views, is easily accessible (approx. 1hr15m drive - 90 km/56mi away).

For those interested in the natural beauty of Guatemala, the surrounding area offers activities such as visits to coffee plantations in the highlands where the unique, aromatic beans are cultivated. Additionally, the coastal town of Monterrico is within reach, known for its black volcanic sand beaches and as a nesting ground for sea turtles, making Puerto Quetzal a strategic starting point for exploring Guatemala’s diverse landscapes.

While at sea, take time to recharge before the next adventure. Lounge by the pool, be spoiled at the spa, dine at any of the onboard restaurants or explore the thrills on each deck until we arrive at the next destination. Make the most of your day at sea by enjoying our Wi-Fi, drink and Speciality Dining Packages. These services are available at an additional cost.

Arrives: 08:00 Departs: 17:00

Puntarenas beckons with its rich tapestry of lush landscapes making it a vibrant spot for adventure and relaxation. This coastal city is a treasure trove of biodiversity, offering thrilling activities like zip-lining and river rafting amidst its natural parks, and is a haven for wildlife enthusiasts eager to spot sloths, scarlet macaws, and capuchin monkeys in their natural habitats.

The city's history is as rich as its landscapes, from its indigenous roots to its emergence as a vital coffee exporting hub. Today, Puntarenas thrives with cultural landmarks such as the Casa de la Cultura and the Marine History Museum, blending educational experiences with natural exploration. Whether it's wandering through the Paseo de los Turistas, visiting the NATUWA Macaw Sanctuary, or exploring the Monteverde Cloud Forest, Puntarenas offers a unique blend of cultural and ecological wonders for every traveller.

Port:Puerto Caldera

Puerto Caldera's cruise terminal is approximately 23 kilometers (about 14 miles) from the city of Puntarenas, around 30 minutes away. For transportation, you can opt for taxis, which are readily available at the port, or consider an organized shore excursion to maximize your visit. A must-see is the Monteverde Cloud Forest Reserve, offering a glimpse into the country's diverse flora and fauna.

While at sea, take time to recharge before the next adventure. Lounge by the pool, be spoiled at the spa, dine at any of the onboard restaurants or explore the thrills on each deck until we arrive at the next destination. Make the most of your day at sea by enjoying our Wi-Fi, drink and Speciality Dining Packages. These services are available at an additional cost.

Arrives: 06:00 Departs: 18:00

The Panama Canal, a marvel of engineering, links the Atlantic and Pacific Oceans, facilitating global maritime trade. Stretching approximately 80km/50mi, this intricate waterway features three locks - Miraflores, Pedro Miguel, and Gatun - that elevate and lower vessels to overcome the variation in sea levels.

The Miraflores Locks' visitor center offers an insightful experience, allowing observers to witness massive ships navigating the locks. The Gatun Locks, a crucial part of the canal, showcase the impressive process of raising and lowering water levels to enable the passage of ships.

Traversing the Panama Canal provides a firsthand glimpse into the intricate operations that have shaped international shipping for over a century.

Arrives: 11:30 Departs: 19:00

Cartagena is a feast for the senses, with its consistently warm air, bright colours, history and nightlife. Filled with legends, romance and splendour, the walled city features Spanish colonial architecture, cobblestone streets, and cultural sites. Ships will dock at this port.

Top Things to Do in Cartagena:

  • join a walking tour through the city
  • visit the Rosario Islands
  • explore the Castillo San Felipe de Barajas
  • visit the chocolate or emerald museums
  • wander the streets of Old Town and the Plaza Santo Domingo

While at sea, take time to recharge before the next adventure. Lounge by the pool, be spoiled at the spa, dine at any of the onboard restaurants or explore the thrills on each deck until we arrive at the next destination. Make the most of your day at sea by enjoying our Wi-Fi, drink and Speciality Dining Packages. These services are available at an additional cost.

Arrives: 07:00 Departs: 16:00

Georgetown, the capital of the Cayman Islands, serves as a vibrant hub of activity and culture. Located on Grand Cayman, it is known for its excellent duty-free shopping, ranging from luxury boutiques to local crafts. The city also boasts a rich maritime history, which can be explored in depth at the Cayman Islands National Museum.

Visitors arriving by cruise are welcomed by the picturesque harbour and its crystal-clear waters, ideal for snorkelling and diving. Just offshore, the famous Stingray City offers a unique opportunity to swim alongside and feed the friendly southern stingrays in their natural habitat.

While at sea, take time to recharge before the next adventure. Lounge by the pool, be spoiled at the spa, dine at any of the onboard restaurants or explore the thrills on each deck until we arrive at the next destination. Make the most of your day at sea by enjoying our Wi-Fi, drink and Speciality Dining Packages. These services are available at an additional cost.

Arrives: 05:00

Tampa Bay is a lively port city located off the beautiful Gulf Coast of Central Florida. Ripe for exploration, Tampa is a great location to spend a couple of days before or after your cruise.

The Ybor City district is alive with history, shopping and fine dining. Thrill seekers can head to Busch Gardens, home to spectacular roller coasters guaranteed to get your heart racing and no trip to Tampa is complete without discovering why its beaches are consistently ranked among the best in the country.

Ships will dock at the Port Tampa Bay cruise terminal.

Note: Ship ports may not be located in the starting & ending cities listed. Port and transfer details will be provided in your travel documentation. The provided itinerary is for informational purposes only. Activities and sightseeing attractions listed may not be available or achievable within the time in port.

Life On Board

Royal Caribbean
 (17) Reviews
Total No. of Cruises 744
Royal Caribbean International is known for driving innovation at sea and has continuously redefined cruise holidays since its launch in 1969. Each successive class of ships is an architectural marvel and pushes the envelope of what is possible on a cruise ship. Onboard, the global cruise line has debuted countless industry more 'firsts' – such as rock climbing, ice skating and surfing at sea – to capture the imagination of families and adventurous holiday-makers alike. Throughout, guests sail on exciting itineraries to some of the world’s most-popular destinations and enjoy Royal Caribbean’s friendly and engaging service.
Serenade of the Seas
Serenade of the Seas

Enjoy a cruising vacation on Serenade of the Seas, with professional service and on board activities for all ages. Read more

The Royal Experience
The Royal Experience

Showcasing impeccable award winning service, and best in class innovations, the Royal experience is bound to exceed expectations. Read more

On board Activities
On board Activities

With an abundance of on board activities, a range of classes and fitness facilities, life on the Serenade will offer you plenty to do. Read more

Foodie Heaven
Foodie Heaven

Tantalise your tastebuds in the global flavours of the complimentary and specialty dining options, from casual treats to fine dining. Read more

That's Entertainment
That's Entertainment

You will be dazzled by the world class original stage performances, guest performers, dancing and musicians to serenade you every night. Read more

Relax and Revive
Relax and Revive

With a luxury on board spa offering indulgent professional treatments, an adult-only solarium and an elegant library, me-time is a thing on board. Read more

Dates & Pricing USD USD

Cabin Layout Options:

Select Cabin Preference:

From $1,729
From $2,159
From $2,879
From $5,313
Thursday 07 Oct 2027 07 Oct 27 San Diego
Friday 22 Oct 2027 22 Oct 27 Tampa
Details
Serenade of the Seas
Bonus Onboard Credit
Exclusive Savings
Inside
US$1,729
Save $696
Twin Share (Per Personpp)
Note
Tour & cruises prices are per person. Prices shown have savings applied, are subject to availability and may be withdrawn at any time without notice. Pricing and trip details are correct at this point in time, however are subject to confirmation at the time of booking and are subject to change by Royal Caribbean. For cruise itineraries, cabin images are sourced from the cruise-line and should be treated as indicative only. Cabin inclusions, upholsteries and room layout may differ to the image(s) shown depending on the ship selected and your sailing dates.

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