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Cruises from San Diego

Choose from 75 unique cruises starting in San Diego, and traveling to Buenos Aires, Fort Lauderdale, London, Miami, Santiago and more. December and January are the most popular months to join a cruise from San Diego and you can select from 135 departures available from five leading cruise lines.
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75 Cruises (135 Cruise Departures)
15 Day Grand World Voyage with Holland America
Cruise

15 Days (14 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Volendam
Departure: 03 May 2026
Visit: USA, Mexico, El Salvador, Panama, Colombia
Advantage Fare
Inside
$2,399
Oceanview
$3,249
Balcony
$6,699
Suite
-
From
US$2,399
Per Person
View Trip
18 Day Panama Canal & Latin America Cruise: Mexico, Costa Rica & Colombia with Azamara Cruises
Cruise
 (5)

18 Days (17 Nights) San Diego to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 May 2027
Visit: USA, Mexico, Guatemala, El Salvador, Costa Rica, Panama, Colombia
Azamara Always Included
Inside
$6,129
Oceanview
$6,609
Balcony
$7,499
Suite
$12,339
From
US$6,129
Per Person
View Trip
17 Day Mexican Riviera Holiday with Holland America
Cruise
 (2)

17 Days (16 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 23 December 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$2,729
Oceanview
$3,439
Balcony
$3,969
Suite
$5,629
From
US$2,729
Per Person
View Trip
25 Day Mexico Riviera & Circle Hawaii with Holland America
Cruise
 (2)

25 Days (24 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 02 January 2027
Visit: USA, Mexico
Fare Saver
Inside
$2,549
Oceanview
$3,309
Balcony
$3,969
Suite
$6,439
From
US$2,549
Per Person
View Trip
8 Day Mexican Riviera with Holland America
Cruise
 (2)

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ships: Koningsdam, Zaandam
Departures: Dec 2026 to Dec 2027
Visit: USA, Mexico
Fare Saver
Book Early & Have It All Fare Option
Inside
$849
Oceanview
$949
Balcony
$1,699
Suite
$2,549
From
US$849
Per Person
View Trip
18 Day Circle Hawaii with Holland America
Cruise
 (2)

18 Days (17 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 09 January 2027
Visit: USA, Mexico
Fare Saver
Inside
$1,799
Oceanview
$2,499
Balcony
$3,099
Suite
$4,799
From
US$1,799
Per Person
View Trip
8 Day Classic California Coast with Holland America
Cruise
 (2)

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 14 November 2026
Visit: USA, Mexico
Fare Saver
Inside
$799
Oceanview
$899
Balcony
$1,099
Suite
$1,749
From
US$799
Per Person
View Trip
19 Day Circle Hawaii with Holland America
Cruise
 (3)

19 Days (18 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 18 November 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$2,334
Oceanview
$2,634
Balcony
$5,034
Suite
$9,734
From
US$2,334
Per Person
View Trip
29 Day Mexico Riviera, Pacific Coastal & Circle Hawaii with Holland America
Cruise
 (2)

29 Days (28 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Koningsdam
Departure: 01 April 2028
Visit: USA, Mexico, Canada
Book Early & Have It All Fare Option
Inside
$3,769
Oceanview
$4,959
Balcony
$5,579
Suite
$7,569
From
US$3,769
Per Person
View Trip
14 Day Historical Baja Peninsula with Holland America
Cruise
 (3)

14 Days (13 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 04 April 2027
Visit: USA, Mexico
Fare Saver
Inside
$1,399
Oceanview
$1,599
Balcony
$3,099
Suite
$6,199
From
US$1,399
Per Person
View Trip
8 Day Mexican Riviera From San Diego To San Diego with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Star
Departures: Jan 2027 to Jan 2027
Visit: USA, Mexico
Inside
$599
Oceanview
$659
Balcony
$889
Suite
$1,159
From
US$599
Per Person
View Trip
15 Day Mexican Riviera with Holland America
Cruise
 (3)

15 Days (14 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 13 November 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$1,954
Oceanview
$2,414
Balcony
$2,734
Suite
$3,634
From
US$1,954
Per Person
View Trip
8 Day Baja Peninsula with Holland America
Cruise
 (2)

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 23 October 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$1,029
Oceanview
$1,279
Balcony
$1,579
Suite
$2,079
From
US$1,029
Per Person
View Trip
12 Day Mexican Riviera & Sea Of Cortez with Holland America
Cruise
 (2)

12 Days (11 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 07 December 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$1,354
Oceanview
$1,704
Balcony
$2,004
Suite
$2,604
From
US$1,354
Per Person
View Trip
36 Day San Diego To London Grand Voyage with Azamara Cruises
Cruise
 (5)

36 Days (35 Nights) San Diego to London
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 May 2027
Visit: USA, Mexico, Guatemala, El Salvador (+7 more), Costa Rica, Panama, Colombia, Canada, Ireland, England, France
Azamara Always Included
Inside
-
Oceanview
$11,439
Balcony
$12,429
Suite
$22,629
From
US$11,439
Per Person
View Trip
22 Day Inca Coast Discovery Segment with Holland America
Cruise
 (3)

22 Days (21 Nights) San Diego to Santiago
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 12 October 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Ecuador, Peru, Chile
Book Early & Have It All Fare Option
Inside
$2,884
Oceanview
$3,164
Balcony
$4,634
Suite
$7,164
From
US$2,884
Per Person
View Trip
15 Day Baja Peninsula & Classic California Coast with Holland America
Cruise
 (3)

15 Days (14 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 06 November 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$1,914
Oceanview
$2,394
Balcony
$2,694
Suite
$3,554
From
US$1,914
Per Person
View Trip
11 Day Mexican Riviera & Sea Of Cortez with Holland America
Cruise
 (2)

11 Days (10 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departures: Nov 2026 to Nov 2027
Visit: USA, Mexico
Fare Saver
Book Early & Have It All Fare Option
Inside
$899
Oceanview
$1,099
Balcony
$1,299
Suite
$2,199
From
US$899
Per Person
View Trip
12 Day Mexican Riviera & Pacific Coast with Holland America
Cruise
 (3)

12 Days (11 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ships: Koningsdam, Zaandam
Departures: Apr 2026 to Apr 2028
Visit: USA, Mexico, Canada
Multiple Deals Available
Inside
$954
Oceanview
$1,054
Balcony
$1,899
Suite
$2,599
From
US$954
Per Person
View Trip
13 Day Mexican Riviera Holiday with Holland America
Cruise
 (2)

13 Days (12 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 18 December 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$1,954
Oceanview
$2,384
Balcony
$2,814
Suite
$3,904
From
US$1,954
Per Person
View Trip
19 Day Circle Hawaii with Holland America
Cruise
 (2)

19 Days (18 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 26 January 2027
Visit: USA, Mexico
Fare Saver
Inside
$1,899
Oceanview
$2,599
Balcony
$2,999
Suite
$4,899
From
US$1,899
Per Person
View Trip
19 Day Baja Peninsula, Mexican Riviera & Pacific Coast with Holland America
Cruise
 (3)

19 Days (18 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Koningsdam
Departures: Mar 2027 to Mar 2028
Visit: USA, Mexico, Canada
Fare Saver
Book Early & Have It All Fare Option
Inside
$1,869
Oceanview
$2,139
Balcony
$2,949
Suite
$4,299
From
US$1,869
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Feb 2027 to Mar 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$394
Oceanview
$455
Balcony
$525
Suite
$704
From
US$394
Save 192
Per Person
View Trip
8 Day Mexican Riviera with Holland America
Cruise
 (3)

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departures: Mar 2027 to Apr 2028
Visit: USA, Mexico
Fare Saver
Book Early & Have It All Fare Option
Inside
$979
Oceanview
$1,109
Balcony
$1,429
Suite
$1,929
From
US$979
Per Person
View Trip
17 Day Panama Canal with Holland America
Cruise
 (3)

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 02 October 2026
Visit: USA, Mexico, Guatemala, El Salvador, Panama, Colombia, Bahamas
Fare Saver
Inside
$1,629
Oceanview
$1,689
Balcony
$2,759
Suite
$4,939
From
US$1,629
Per Person
View Trip
36 Day Hawaii, Tahiti & Marquesas Legendary Voyage with Holland America
Cruise
 (3)

36 Days (35 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 14 October 2027
Visit: USA, Kiribati, French Polynesia
Book Early & Have It All Fare Option
Inside
$4,324
Oceanview
$4,924
Balcony
$10,724
Suite
$19,424
From
US$4,324
Per Person
View Trip
12 Day Mexican Riviera & Sea Of Cortez with Holland America
Cruise
 (2)

12 Days (11 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departures: Oct 2026 to Dec 2026
Visit: USA, Mexico
Fare Saver
Inside
$899
Oceanview
$1,049
Balcony
$1,399
Suite
$2,299
From
US$899
Per Person
View Trip
36 Day Legendary Hawaii, Tahiti & Marquesas with Holland America
Cruise
 (3)

36 Days (35 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 15 October 2026
Visit: USA, Kiribati, French Polynesia
Fare Saver
Inside
-
Oceanview
$4,699
Balcony
$11,599
Suite
-
From
US$4,699
Per Person
View Trip
8 Day Baja Peninsula & Sea Of Cortez with Holland America
Cruise
 (3)

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ships: Koningsdam, Zaandam, Zuiderdam
Departures: Oct 2026 to Mar 2028
Visit: USA, Mexico
Fare Saver
Book Early & Have It All Fare Option
Inside
$709
Oceanview
$779
Balcony
$1,199
Suite
$1,799
From
US$709
Per Person
View Trip
6 Day Pacific Coastal Cruise with Holland America
Cruise
 (2)

6 Days (5 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Koningsdam
Departure: 27 April 2026
Visit: USA, Canada
Advantage Fare
Inside
$424
Oceanview
$474
Balcony
$644
Suite
$1,124
From
US$424
Per Person
View Trip
Results: 31-60 of 75

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Trip Lengths

1 Month 10 Day 2 Week 3 Day 3 Week 4 Week 7 Day

Departure Months

April May October November December January February March

Cities

Amsterdam Anchorage Baltimore Boston Cape Liberty Fort Lauderdale Galveston Honolulu Jacksonville Los Angeles Miami New Orleans New York Orlando Philadelphia San Diego San Francisco San Juan Seattle Seward Tampa Vancouver

Routes

Anchorage to Vancouver Baltimore to Baltimore Barcelona to Fort Lauderdale Barcelona to Miami Boston to Montreal Boston to Quebec City Boston to Boston Bridgetown to Miami Cape Liberty to Cape Liberty Fort Lauderdale to London Fort Lauderdale to Barcelona Fort Lauderdale to Fort Lauderdale Fort Lauderdale to San Diego Fort Lauderdale to Vancouver Galveston to Galveston Honolulu to Tahiti Honolulu to Vancouver Jacksonville to Jacksonville London to Fort Lauderdale London to New York Los Angeles to Miami Los Angeles to Vancouver Los Angeles to Los Angeles Miami to San Juan Miami to Lisbon Miami to Los Angeles Miami to Rome Miami to Bridgetown Miami to Panama City Miami to Barcelona Miami to Miami Miami to London Montreal to Boston Montreal to Miami Montreal to New York New Orleans to New Orleans New York to Montreal New York to New York New York to London Orlando to Orlando Panama City to Miami Philadelphia to Philadelphia Quebec City to Boston Rome to Fort Lauderdale Rotterdam to Fort Lauderdale San Diego to Fort Lauderdale San Diego to Vancouver San Diego to San Diego San Francisco to San Francisco San Juan to Miami Seattle to Vancouver Seattle to Seattle Seward to Vancouver Sydney to Honolulu Tahiti to Honolulu Tampa to Tampa Toronto to Boston Vancouver to Los Angeles Vancouver to Honolulu Vancouver to Seward Vancouver to Seattle Vancouver to Anchorage Vancouver to San Diego

Country Routes

Argentina to USA Australia to USA Barbados to USA Canada to USA Chile to USA Dominican Republic to USA England to USA France to USA French Polynesia to USA Greece to USA Holland to USA Iceland to USA Italy to USA Japan to USA New Zealand to USA Panama to USA Peru to USA Portugal to USA Puerto Rico to USA Spain to USA USA to Portugal USA to Germany USA to Iceland USA to Puerto Rico USA to Brazil USA to Dominican Republic USA to Argentina USA to Australia USA to Barbados USA to Canada USA to Chile USA to England USA to French Polynesia USA to Holland USA to Italy USA to Japan USA to Panama USA to Peru USA to Spain

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