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Cruises from San Diego

Choose from 64 unique cruises starting in San Diego, and traveling to Fort Lauderdale, London, Miami, Sydney, Tahiti and more. December, January and March are the most popular months to join a cruise from San Diego and you can select from 132 departures available from six leading cruise lines.
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3 Days
94 Days
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64 Cruises (132 Cruise Departures)
94 Day Grand Australia & New Zealand with Holland America
Cruise
 (3)

94 Days (93 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 04 January 2026
Visit: USA, American Samoa, Samoa, Fiji (+8 more), New Caledonia, Vanuatu, Solomon Islands, Papua New Guinea, Australia, New Zealand, Tonga, French Polynesia
Advantage Fare
Exclusive Savings
Inside
$16,351
Oceanview
$18,703
Balcony
$38,891
Suite
-
From
US$16,351
Save 248
Per Person
View Trip
16 Day Panama Canal with Holland America
Cruise
 (3)

16 Days (15 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Zaandam
Departure: 19 December 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Colombia
Book Early & Have It All Fare Option
Inside
$2,464
Oceanview
$2,764
Balcony
$4,789
Suite
$9,101
From
US$2,464
Per Person
View Trip
12 Day Mexican Riviera & Sea Of Cortez with Holland America
Cruise
 (3)

12 Days (11 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 07 April 2026
Visit: USA, Mexico
Fare Saver
Inside
$1,149
Oceanview
$1,349
Balcony
$3,049
Suite
-
From
US$1,149
Per Person
View Trip
19 Day Circle Hawaii Holiday with Holland America
Cruise
 (3)

19 Days (18 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 19 November 2026
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$2,149
Oceanview
$2,299
Balcony
$4,790
Suite
$9,817
From
US$2,149
Per Person
View Trip
12 Day Mexican Riviera & Pacific Coast with Holland America
Cruise
 (2)

12 Days (11 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ships: Koningsdam, Zaandam
Departures: Apr 2026 to Mar 2027
Visit: USA, Mexico, Canada
Fare Saver
Book Early & Have It All Fare Option
Inside
$1,099
Oceanview
$1,199
Balcony
$2,094
Suite
$2,844
From
US$1,099
Per Person
View Trip
12 Day Mexican Riviera & Sea Of Cortez with Holland America
Cruise
 (2)

12 Days (11 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departures: Oct 2026 to Dec 2026
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$1,204
Oceanview
$1,684
Balcony
$1,834
Suite
$2,584
From
US$1,204
Per Person
View Trip
18 Day Panama Canal & Latin America Cruise: Mexico, Costa Rica & Colombia with Azamara Cruises
Cruise
 (4)

18 Days (17 Nights) San Diego to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 May 2027
Visit: USA, Mexico, Guatemala, El Salvador, Costa Rica, Panama, Colombia
Azamara Always Included
Exclusive Savings
Inside
$5,295
Oceanview
$5,741
Balcony
$6,604
Suite
$10,766
From
US$5,295
Save 114
Per Person
View Trip
13 Day Historical Baja Peninsula with Holland America
Cruise
 (3)

13 Days (12 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 07 December 2026
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$1,299
Oceanview
$1,399
Balcony
$3,149
Suite
$5,883
From
US$1,299
Per Person
View Trip
36 Day Hawaii, Tahiti & Marquesas with Holland America
Cruise
 (2)

36 Days (35 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 13 February 2027
Visit: USA, Kiribati, French Polynesia
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$4,263
Oceanview
$6,125
Balcony
$6,517
Suite
$9,163
From
US$4,263
Per Person
View Trip
14 Day Historical Baja Peninsula with Holland America
Cruise
 (3)

14 Days (13 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 04 April 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$1,704
Oceanview
$1,814
Balcony
$3,654
Suite
$6,526
From
US$1,704
Per Person
View Trip
36 Day Hawaii, Tahiti & Marquesas Legendary Voyage with Holland America
Cruise
 (2)

36 Days (35 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 19 February 2028
Visit: USA, Kiribati, French Polynesia
Book Early & Have It All Fare Option
Exclusive Savings
Inside
$4,906
Oceanview
$6,278
Balcony
$7,013
Suite
$9,120
From
US$4,906
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Feb 2027 to Mar 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$452
Oceanview
$542
Balcony
$615
Suite
$704
From
US$452
Save 225
Per Person
View Trip
62 Day Grand Australia & New Zealand with Holland America
Cruise
 (3)

62 Days (61 Nights) San Diego to Sydney
Cruise Line: Holland America
Ship: Zaandam
Departure: 04 January 2026
Visit: USA, American Samoa, Samoa, Fiji (+5 more), New Caledonia, Vanuatu, Solomon Islands, Papua New Guinea, Australia
Advantage Fare
Exclusive Savings
Inside
$10,596
Oceanview
$12,262
Balcony
$30,196
Suite
-
From
US$10,596
Per Person
View Trip
8 Day Wine Country & Pacific Northwest with Holland America
Cruise
 (3)

8 Days (7 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Zaandam
Departure: 17 April 2027
Visit: USA, Canada
Book Early & Have It All Fare Option
Inside
$964
Oceanview
$1,044
Balcony
$2,414
Suite
$3,551
From
US$964
Per Person
View Trip
6 Day Pacific Coastal Cruise with Holland America
Cruise
 (2)

6 Days (5 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Koningsdam
Departure: 27 April 2026
Visit: USA, Canada
Fare Saver
Inside
$509
Oceanview
$549
Balcony
$599
Suite
$1,099
From
US$509
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departure: 29 January 2027
Visit: USA, Mexico, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,899
Oceanview
$2,049
Balcony
$3,044
Suite
$4,113
From
US$1,899
Per Person
View Trip
8 Day Ensenada, Cabo & Mazatlan with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Feb 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$713
Oceanview
$877
Balcony
$969
Suite
$1,935
From
US$713
Save 399
Per Person
View Trip
19 Day Baja Peninsula, Mexican Riviera & Pacific Coast with Holland America
Cruise
 (2)

19 Days (18 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ships: Koningsdam, Zaandam
Departures: Apr 2026 to Mar 2027
Visit: USA, Mexico, Canada
Fare Saver
Book Early & Have It All Fare Option
Inside
$1,759
Oceanview
$1,899
Balcony
$3,349
Suite
$4,663
From
US$1,759
Per Person
View Trip
17 Day Panama Canal with Holland America
Cruise

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Eurodam
Departure: 08 October 2026
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Book Early & Have It All Fare Option
Inside
$2,219
Oceanview
$2,579
Balcony
$3,607
Suite
$5,978
From
US$2,219
Per Person
View Trip
11 Day Mexican Riviera & Sea Of Cortez with Holland America
Cruise
 (2)

11 Days (10 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 28 November 2026
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$1,169
Oceanview
$1,639
Balcony
$1,769
Suite
$2,489
From
US$1,169
Per Person
View Trip
5 Day Pacific Coastal Cruise with Holland America
Cruise

5 Days (4 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ships: Koningsdam, Nieuw Amsterdam, Zaandam
Departures: May 2026 to Apr 2027
Visit: USA, Canada
Fare Saver
Inside
$399
Oceanview
$449
Balcony
$764
Suite
$1,014
From
US$399
Per Person
View Trip
6 Day Mexican Riviera From San Diego To San Diego with Norwegian Cruise Line
Cruise

6 Days (5 Nights) San Diego to San Diego
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Jade
Departure: 07 February 2026
Visit: USA, Mexico
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$1,869
From
US$1,869
Save 50
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$692
Oceanview
$852
Balcony
$1,004
Suite
$1,682
From
US$692
Save 416
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Dec 2026
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$1,070
Oceanview
$1,131
Balcony
$1,484
Suite
$2,333
From
US$1,070
Save 537
Per Person
View Trip
8 Day Mexican Riviera From San Diego To San Diego with Norwegian Cruise Line
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Jade
Departure: 03 January 2026
Visit: USA, Mexico
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$1,994
From
US$1,994
Save 55
Per Person
View Trip
3 Day Ensenada Cruise with Royal Caribbean
Cruise

3 Days (2 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 October 2026
Visit: USA, Mexico
Exclusive Savings
Inside
$349
Oceanview
$409
Balcony
$501
Suite
$781
From
US$349
Save 173
Per Person
View Trip
8 Day Mexican Riviera with Holland America
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zuiderdam
Departure: 16 January 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$949
Oceanview
$1,204
Balcony
$1,349
Suite
$2,554
From
US$949
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Dec 2026 to Apr 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$404
Oceanview
$479
Balcony
$554
Suite
$657
From
US$404
Save 226
Per Person
View Trip
8 Day Cabo Overnight, Catalina & Ensenada with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 13 December 2026
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$743
Oceanview
$903
Balcony
$1,155
Suite
$1,886
From
US$743
Save 395
Per Person
View Trip
8 Day Pacific Coastal Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to Vancouver
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 02 May 2027
Visit: USA, Canada
Bonus Onboard Credit
Exclusive Savings
Inside
$658
Oceanview
$688
Balcony
$838
Suite
$1,688
From
US$658
Save 331
Per Person
View Trip
Results: 31-60 of 64

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Departure Months

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Cities

Amsterdam Anchorage Baltimore Boston Cape Liberty Fort Lauderdale Galveston Honolulu Jacksonville Los Angeles Miami New Orleans New York Orlando Philadelphia San Diego San Francisco Seattle Seward Tampa Vancouver

Routes

Anchorage to Vancouver Baltimore to Baltimore Barcelona to Fort Lauderdale Barcelona to Miami Boston to Montreal Boston to Quebec City Boston to Boston Bridgetown to Miami Cape Liberty to Cape Liberty Fort Lauderdale to Los Angeles Fort Lauderdale to Barcelona Fort Lauderdale to Fort Lauderdale Fort Lauderdale to San Diego Fort Lauderdale to Vancouver Galveston to Galveston Honolulu to Tahiti Honolulu to Vancouver Jacksonville to Jacksonville London to Fort Lauderdale London to New York Los Angeles to Miami Los Angeles to Vancouver Los Angeles to Los Angeles Miami to San Juan Miami to Lisbon Miami to Los Angeles Miami to Rome Miami to Bridgetown Miami to Panama City Miami to Barcelona Miami to Miami Miami to London Montreal to Boston Montreal to Miami Montreal to New York New Orleans to New Orleans New York to Montreal New York to New York New York to London Orlando to Orlando Panama City to Miami Philadelphia to Philadelphia Quebec City to Boston Rome to Miami Rome to Fort Lauderdale Rotterdam to Fort Lauderdale San Diego to Fort Lauderdale San Diego to Vancouver San Diego to San Diego San Francisco to San Francisco San Juan to Miami Seattle to Vancouver Seattle to Seattle Seward to Vancouver Sydney to Honolulu Tahiti to Honolulu Tampa to Tampa Vancouver to Los Angeles Vancouver to Honolulu Vancouver to Seward Vancouver to Seattle Vancouver to Anchorage Vancouver to San Diego

Country Routes

Argentina to USA Australia to USA Barbados to USA Canada to USA Chile to USA Dominican Republic to USA England to USA France to USA French Polynesia to USA Greece to USA Holland to USA Iceland to USA Italy to USA Japan to USA New Zealand to USA Panama to USA Peru to USA Portugal to USA Puerto Rico to USA Spain to USA USA to Portugal USA to Germany USA to Iceland USA to Puerto Rico USA to Brazil USA to Dominican Republic USA to Australia USA to Barbados USA to Canada USA to Chile USA to England USA to French Polynesia USA to Holland USA to Italy USA to Japan USA to Panama USA to Peru USA to Spain

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