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Cruises from San Diego

Choose from 62 unique cruises starting in San Diego, and traveling to Fort Lauderdale, London, Miami and Vancouver. December and January are the most popular months to join a cruise from San Diego and you can select from 130 departures available from five leading cruise lines.
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36 Days
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62 Cruises (130 Cruise Departures)
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Feb 2027 to Mar 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$442
Oceanview
$512
Balcony
$584
Suite
$715
From
US$442
Save 221
Per Person
View Trip
12 Day Mexican Riviera & Sea Of Cortez with Holland America
Cruise
 (3)

12 Days (11 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 07 April 2026
Visit: USA, Mexico
Have It All Fare Option
Inside
$1,354
Oceanview
$1,404
Balcony
-
Suite
-
From
US$1,354
Per Person
View Trip
19 Day Circle Hawaii Holiday with Holland America
Cruise
 (3)

19 Days (18 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 19 November 2026
Visit: USA, Mexico
Fare Saver
Inside
$1,739
Oceanview
$1,839
Balcony
$4,584
Suite
$10,072
From
US$1,739
Per Person
View Trip
25 Day Mexico Riviera & Circle Hawaii with Holland America
Cruise
 (2)

25 Days (24 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 02 January 2027
Visit: USA, Mexico
Fare Saver
Inside
$2,579
Oceanview
$3,389
Balcony
$3,952
Suite
$6,186
From
US$2,579
Per Person
View Trip
8 Day Wine Country & Pacific Northwest with Holland America
Cruise
 (3)

8 Days (7 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 04 April 2026
Visit: USA, Canada
Have It All Fare Option
Inside
$834
Oceanview
$884
Balcony
$1,284
Suite
-
From
US$834
Per Person
View Trip
36 Day Legendary Hawaii, Tahiti & Marquesas with Holland America
Cruise
 (3)

36 Days (35 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zaandam
Departure: 15 October 2026
Visit: USA, Kiribati, French Polynesia
Fare Saver
Exclusive Savings
Inside
$4,070
Oceanview
$4,560
Balcony
$11,763
Suite
-
From
US$4,070
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Nov 2026
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$697
Oceanview
$777
Balcony
$1,040
Suite
$1,412
From
US$697
Save 386
Per Person
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (6)

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Princess
Ship: Island Princess
Departure: 29 January 2027
Visit: USA, Mexico, Costa Rica, Panama, Aruba
Princess Standard
Inside
$1,749
Oceanview
$1,879
Balcony
$2,949
Suite
$3,744
From
US$1,749
Per Person
View Trip
7 Day Pacific Coastal Cruise with Holland America
Cruise

7 Days (6 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Eurodam
Departure: 17 April 2027
Visit: USA, Canada
Fare Saver
Inside
$859
Oceanview
$959
Balcony
$1,159
Suite
$1,809
From
US$859
Per Person
View Trip
8 Day Classic California Coast with Holland America
Cruise
 (3)

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 13 November 2027
Visit: USA, Mexico
Book Early & Have It All Fare Option
Inside
$1,069
Oceanview
$1,319
Balcony
$1,469
Suite
$1,919
From
US$1,069
Per Person
View Trip
5 Day Pacific Coastal Cruise with Holland America
Cruise
 (3)

5 Days (4 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ships: Koningsdam, Nieuw Amsterdam, Zaandam
Departures: May 2026 to Apr 2028
Visit: USA, Canada
Fare Saver
Inside
$309
Oceanview
$339
Balcony
$714
Suite
$1,034
From
US$309
Per Person
View Trip
19 Day Baja Peninsula, Mexican Riviera & Pacific Coast with Holland America
Cruise
 (3)

19 Days (18 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ships: Koningsdam, Zaandam
Departures: Apr 2026 to Mar 2028
Visit: USA, Mexico, Canada
Have It All Fare Option
Fare Saver
Book Early & Have It All Fare Option
Inside
$1,889
Oceanview
$2,019
Balcony
$3,089
Suite
$4,536
From
US$1,889
Per Person
View Trip
12 Day Mexican Riviera & Sea Of Cortez with Holland America
Cruise
 (2)

12 Days (11 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departures: Oct 2026 to Dec 2026
Visit: USA, Mexico
Fare Saver
Inside
$1,089
Oceanview
$1,289
Balcony
$1,699
Suite
$2,499
From
US$1,089
Per Person
View Trip
6 Day Pacific Coastal Cruise with Holland America
Cruise
 (2)

6 Days (5 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Koningsdam
Departure: 27 April 2026
Visit: USA, Canada
Advantage Fare
Inside
$474
Oceanview
$524
Balcony
$574
Suite
-
From
US$474
Per Person
View Trip
29 Day Mexico Riviera, Pacific Coastal & Circle Hawaii with Holland America
Cruise
 (2)

29 Days (28 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Koningsdam
Departure: 27 March 2027
Visit: USA, Mexico, Canada
Fare Saver
Inside
$3,114
Oceanview
$4,057
Balcony
$4,792
Suite
$6,958
From
US$3,114
Per Person
View Trip
17 Day Panama Canal with Holland America
Cruise
 (3)

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 02 October 2026
Visit: USA, Mexico, Guatemala, El Salvador, Panama, Colombia, Bahamas
Fare Saver
Inside
$1,719
Oceanview
$1,819
Balcony
$2,909
Suite
$4,999
From
US$1,719
Per Person
View Trip
5 Day Pacific Coastal Cruise with Holland America
Cruise

5 Days (4 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Eurodam
Departure: 20 April 2026
Visit: USA, Canada
Fare Saver
Inside
$289
Oceanview
$299
Balcony
$379
Suite
-
From
US$289
Per Person
View Trip
17 Day Panama Canal with Holland America
Cruise

17 Days (16 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Eurodam
Departures: Oct 2026 to Oct 2027
Visit: USA, Mexico, Guatemala, Costa Rica, Panama, Aruba
Fare Saver
Book Early & Have It All Fare Option
Inside
$1,779
Oceanview
$1,879
Balcony
$2,999
Suite
$5,331
From
US$1,779
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 28 January 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$671
Oceanview
$881
Balcony
$1,073
Suite
$2,098
From
US$994
Save 50
Per Person
View Trip
8 Day Mexican Riviera From San Diego To San Diego with Norwegian Cruise Line
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Jade
Departure: 04 April 2026
Visit: USA, Mexico
Inside
$799
Oceanview
$859
Balcony
$1,179
Suite
$1,229
From
US$799
Per Person
View Trip
5 Day Catalina & Ensenada Cruise with Royal Caribbean
Cruise

5 Days (4 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 07 March 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$472
Oceanview
$562
Balcony
$624
Suite
$774
From
US$472
Save 217
Per Person
View Trip
15 Day Mexican Riviera & Baja Peninsula with Holland America
Cruise

15 Days (14 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Zuiderdam
Departure: 16 January 2027
Visit: USA, Mexico
Fare Saver
Inside
$1,599
Oceanview
$1,789
Balcony
$2,359
Suite
$4,562
From
US$1,599
Per Person
View Trip
8 Day Ensenada, Cabo & La Paz Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Apr 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$647
Oceanview
$797
Balcony
$974
Suite
$1,492
From
US$652
Save 408
Per Person
View Trip
15 Day Grand World Voyage with Holland America
Cruise

15 Days (14 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Volendam
Departure: 03 May 2026
Visit: USA, Mexico, El Salvador, Panama, Colombia
Advantage Fare
Inside
$2,399
Oceanview
$3,249
Balcony
$6,591
Suite
-
From
US$2,399
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Dec 2026 to Apr 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$376
Oceanview
$436
Balcony
$518
Suite
$626
From
US$394
Save 226
Per Person
View Trip
9 Day Pacific Coastal Repositioning Cruise with Norwegian Cruise Line
Cruise

9 Days (8 Nights) San Diego to Vancouver
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Jade
Departure: 11 April 2026
Visit: USA, Canada
Inside
$549
Oceanview
$649
Balcony
$1,149
Suite
$1,389
From
US$549
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Nov 2026 to Dec 2026
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$949
Oceanview
$1,119
Balcony
$1,461
Suite
$1,934
From
US$1,401
Save 50
Per Person
View Trip
8 Day Cabo Overnight, Catalina & Ensenada with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 13 December 2026
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$660
Oceanview
$821
Balcony
$1,063
Suite
$1,745
From
US$988
Save 50
Per Person
View Trip
8 Day Cabo, Mazatlan & La Paz Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departure: 27 December 2026
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$1,178
Oceanview
$1,238
Balcony
$1,691
Suite
$2,633
From
US$1,728
Save 50
Per Person
View Trip
4 Day Ensenada Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) San Diego to San Diego
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2026 to Mar 2027
Visit: USA, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$384
Oceanview
$445
Balcony
$537
Suite
$647
From
US$384
Save 250
Per Person
View Trip
Results: 31-60 of 62

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Departure Months

March April May October November December January February

Cities

Amsterdam Anchorage Baltimore Boston Cape Liberty Fort Lauderdale Galveston Honolulu Jacksonville Los Angeles Miami New Orleans New York Orlando Philadelphia San Diego San Francisco San Juan Seattle Seward Tampa Vancouver

Routes

Anchorage to Vancouver Baltimore to Baltimore Barcelona to Fort Lauderdale Barcelona to Miami Boston to Montreal Boston to Quebec City Boston to Boston Bridgetown to Miami Cape Liberty to Cape Liberty Fort Lauderdale to Los Angeles Fort Lauderdale to Barcelona Fort Lauderdale to Fort Lauderdale Fort Lauderdale to San Diego Fort Lauderdale to Vancouver Galveston to Galveston Honolulu to Tahiti Honolulu to Vancouver Jacksonville to Jacksonville London to Fort Lauderdale London to New York Los Angeles to Vancouver Los Angeles to Los Angeles Miami to San Juan Miami to Lisbon Miami to Los Angeles Miami to Rome Miami to Bridgetown Miami to Panama City Miami to Barcelona Miami to Miami Miami to London Montreal to Boston Montreal to Miami Montreal to New York New Orleans to New Orleans New York to Montreal New York to New York New York to London Orlando to Orlando Philadelphia to Philadelphia Quebec City to Boston Rome to Miami Rome to Fort Lauderdale Rotterdam to Fort Lauderdale San Diego to Fort Lauderdale San Diego to Vancouver San Diego to San Diego San Francisco to San Francisco San Juan to Miami Seattle to Vancouver Seattle to Seattle Seward to Vancouver Sydney to Honolulu Tahiti to Honolulu Tampa to Tampa Vancouver to Los Angeles Vancouver to Honolulu Vancouver to Seward Vancouver to Seattle Vancouver to Anchorage Vancouver to San Diego

Country Routes

Argentina to USA Australia to USA Barbados to USA Canada to USA Chile to USA Dominican Republic to USA England to USA French Polynesia to USA Greece to USA Holland to USA Iceland to USA Italy to USA Japan to USA New Zealand to USA Panama to USA Peru to USA Portugal to USA Puerto Rico to USA Spain to USA USA to Portugal USA to Iceland USA to Puerto Rico USA to Brazil USA to Dominican Republic USA to Australia USA to Barbados USA to Canada USA to Chile USA to England USA to French Polynesia USA to Holland USA to Italy USA to Japan USA to Panama USA to Peru USA to Spain

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