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South America Luxury Cruises

Explore the best luxury cruises around South America. Choose from 140 unique cruise itineraries with 161 past traveler reviews from 10 leading cruise lines. January is the most popular month to join a luxury cruise around South America with 253 departures starting between May 2026 and March 2029.
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140 Cruises (253 Cruise Departures)
13 Day Bossa Nova Reverie with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 07 March 2027
Visit: Argentina, Uruguay, Brazil
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$3,899
Oceanview
$4,299
Balcony
-
Suite
-
From
US$3,899
Save 3,899
Per Person
View Trip
11 Day Rio De Janeiro to Buenos Aires with Silversea
Cruise
 (1)

11 Days (10 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Silversea
Ship: Silver Nova
Departure: 07 February 2027
Visit: Brazil, Uruguay, Argentina
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$12,100
Suite
$16,700
From
US$12,100
Per Person
View Trip
11 Day Panama, Ecuadaor & Peru Cruise: Panama City, Manta & Lima (Callao) with Azamara Cruises
Cruise
 (5)

11 Days (10 Nights) Panama City to Valparaiso
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 14 January 2028
Visit: Panama, Ecuador, Peru, Chile
Azamara Always Included
Inside
$3,239
Oceanview
$3,799
Balcony
$4,669
Suite
$6,839
From
US$3,239
Per Person
View Trip
21 Day Bridgetown to Rio De Janeiro with Silversea
Cruise
 (1)

21 Days (20 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Silversea
Ship: Silver Nova
Departure: 18 January 2027
Visit: Barbados, Brazil
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$19,300
Suite
$25,800
From
US$19,300
Save 3,500
Per Person
View Trip
24 Day Brazil & Argentina Cruise: Rio De Janeiro, Salvador & Buenos Aires with Azamara Cruises
Cruise
 (3)

24 Days (23 Nights) Bridgetown to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 25 January 2027
Visit: Barbados, Trinidad and Tobago, French Guiana, Brazil, Uruguay, Argentina
Azamara Circle Member - Quarterly Saving
Azamara Always Included
Inside
$7,659
Oceanview
$8,569
Balcony
$10,739
Suite
$15,359
From
US$7,659
Per Person
View Trip
11 Day Chile Intensive Cruise: Puerto Montt, Castro & Punta Arenas with Azamara Cruises
Cruise
 (5)

11 Days (10 Nights) Valparaiso to Ushuaia
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina
Azamara Always Included
Inside
$3,249
Oceanview
$3,809
Balcony
$4,669
Suite
$7,169
From
US$3,249
Per Person
View Trip
27 Day Brazil Intensive Cruise: Sao Paulo, Rio De Janiero & Salvador with Azamara Cruises
Cruise
 (5)

27 Days (26 Nights) Buenos Aires to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 16 February 2028
Visit: Argentina, Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Inside
$9,139
Oceanview
$10,399
Balcony
$12,569
Suite
$18,289
From
US$9,139
Per Person
View Trip
22 Day Patagonian Panorama with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Lima to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 03 January 2027
Visit: Peru, Chile, Argentina, Falkland Islands, Uruguay
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$6,549
Oceanview
$7,049
Balcony
-
Suite
$13,549
From
US$6,549
Save 6,549
Per Person
View Trip
13 Day Brazil Intensive Cruise: Sao Paulo, Poto Belo & Rio De Janeiro with Azamara Cruises
Cruise
 (5)

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 16 February 2028
Visit: Argentina, Uruguay, Brazil
Azamara Always Included
Inside
$4,239
Oceanview
$4,999
Balcony
$5,989
Suite
$8,639
From
US$4,239
Per Person
View Trip
15 Day Brazil Intensive Cruise: Salvador, Natal & Belem with Azamara Cruises
Cruise
 (5)

15 Days (14 Nights) Rio de Janeiro to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 28 February 2028
Visit: Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Inside
$4,679
Oceanview
$5,509
Balcony
$6,639
Suite
$9,739
From
US$4,679
Per Person
View Trip
7 Day Ocean Voyage: Ushuaia - Buenos Aires with Ponant
Cruise
 (2)

7 Days (6 Nights) Ushuaia to Buenos Aires
Cruise Line: Ponant
Ship: Le Boreal
Departure: 12 March 2028
Visit: Argentina
Inside
-
Oceanview
$1,950
Balcony
$2,080
Suite
$3,040
From
US$1,950
Per Person
View Trip
15 Day Chilean Heritage & Fjords with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Lima to Punta Arenas
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 19 January 2028
Visit: Peru, Chile
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$4,549
Oceanview
$4,799
Balcony
$6,299
Suite
-
From
US$4,549
Save 4,549
Per Person
View Trip
12 Day Nights Of Samba & Tango with Regent Seven Seas
Cruise

12 Days (11 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 22 January 2027
Visit: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,149
Suite
$14,149
From
US$13,149
Save 13,149
Per Person
View Trip
17 Day Patagonia & the Chilean Fjords with Scenic
New ReleaseCruise

17 Days (16 Nights) Buenos Aires to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 14 November 2027
Visit: Argentina, Uruguay, Chile
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$19,958
Suite
$24,422
From
US$19,958
Save 3,587
Per Person
View Trip
9 Day Cruising the Galapagos Islands with Tauck
Tour + Cruise

9 Days Guayaquil to Guayaquil
Operated By: Tauck
Departures: Nov 2026 to Dec 2027
Visit: Ecuador, Galapagos
From
US$9,490
Per Person
View Trip
12 Day Rhythms of the Brazilian Coastline with Scenic
New ReleaseCruise

12 Days (11 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Scenic
Ships: Scenic Eclipse I
Departures: Mar 2027 to Mar 2028
Visit: Argentina, Uruguay, Brazil
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,707
Suite
$11,624
From
US$9,707
Save 3,193
Per Person
View Trip
15 Day The Best of Chilean Fjords with Ponant
Cruise

15 Days (14 Nights) Valparaiso to Buenos Aires
Cruise Line: Ponant
Ships: L'Austral, Le Lyrial
Departures: Nov 2026 to Nov 2026
Visit: Chile, Argentina
Inside
-
Oceanview
-
Balcony
$13,000
Suite
$24,410
From
US$13,000
Per Person
View Trip
13 Day Chilean Fjords & The Glaciers of The Beagle Channel with Scenic
Cruise

13 Days (12 Nights) Santiago to Buenos Aires
Cruise Line: Scenic
Ships: Scenic Eclipse I
Departures: Nov 2026 to Nov 2028
Visit: Chile, Argentina
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,645
Suite
$25,734
From
US$15,645
Save 4,270
Per Person
View Trip
17 Day Trinidad To Rio: South American Expedition with Seabourn
Cruise

17 Days (16 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Seabourn
Ship: Seabourn Venture
Departures: Oct 2026 to Oct 2028
Visit: Barbados, Trinidad and Tobago, French Guiana, Brazil
Yours to Explore
Inside
-
Oceanview
-
Balcony
-
Suite
$10,299
From
US$10,299
Per Person
View Trip
26 Day Peru, Amazon & the Chilean Fjords Expedition - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

26 Days Lima to Buenos Aires
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 22 October 2026
Trip Styles: Coach, Cruise, Wildlife, Scenic
Visit: Peru, Chile, Argentina
Inside
-
Oceanview
-
Balcony
$51,100
Suite
-
From
US$51,100
Per Person
View Trip
14 Day Chilean Fjords & The Glaciers of The Beagle Channel with Scenic
Cruise

14 Days (13 Nights) Buenos Aires to Santiago
Cruise Line: Scenic
Ships: Scenic Eclipse II
Departures: Mar 2027 to Mar 2028
Visit: Chile, Argentina
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,345
Suite
$23,332
From
US$16,345
Save 4,045
Per Person
View Trip
21 Day Rio De Janeiro to Bridgetown with Silversea
Cruise

21 Days (20 Nights) Rio de Janeiro to Bridgetown
Cruise Line: Silversea
Ship: Silver Ray
Departure: 29 February 2028
Visit: Brazil, French Guiana, Barbados
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,600
Suite
$26,500
From
US$16,600
Save 3,500
Per Person
View Trip
15 Day Cartagena to Valparaiso with Silversea
Cruise

15 Days (14 Nights) Cartagena to Valparaiso
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 15 January 2028
Visit: Colombia, Panama, Ecuador, Peru, Chile
All-Inclusive Fare
Inside
-
Oceanview
$8,000
Balcony
$9,600
Suite
$26,400
From
US$8,000
Per Person
View Trip
15 Day San Cristobal to San Cristobal with Silversea
Cruise

15 Days (14 Nights) Quito to Quito
Cruise Line: Silversea
Ship: Silver Origin
Departure: 29 August 2026
Visit: Galapagos, Ecuador
All-Inclusive Plus Fare
Inside
-
Oceanview
-
Balcony
$21,400
Suite
$38,300
From
US$21,400
Per Person
View Trip
27 Day Treasures of South America: Chilean Fjords to the Iguazu falls - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

27 Days Buenos Aires to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 28 February 2027
Trip Styles: Coach, Cruise, Scenic
Visit: Argentina, Chile, Brazil
Inside
-
Oceanview
-
Balcony
$36,115
Suite
$83,955
From
US$36,115
Per Person
View Trip
22 Day Treasures of South America with Chilean Fjords - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

22 Days Santiago to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 04 November 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Brazil
Inside
-
Oceanview
-
Balcony
$26,680
Suite
-
From
US$26,680
Per Person
View Trip
12 Day Rhythms of the Brazilian Coastline with Scenic
New ReleaseCruise

12 Days (11 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 03 November 2027
Visit: Brazil, Uruguay, Argentina
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,751
Suite
$12,978
From
US$10,751
Save 2,679
Per Person
View Trip
18 Day Valparaiso to Buenos Aires with Silversea
Cruise

18 Days (17 Nights) Valparaiso to Buenos Aires
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 29 January 2028
Visit: Chile, Argentina, Falkland Islands
All-Inclusive Fare
Inside
-
Oceanview
$13,800
Balcony
$15,500
Suite
$42,500
From
US$13,800
Per Person
View Trip
15 Day Peru & the Galapagos Islands with Tauck
Tour + Cruise

15 Days Lima to Guayaquil
Operated By: Tauck
Departures: May 2026 to Oct 2027
Visit: Peru, Ecuador, Galapagos
From
US$14,190
Per Person
View Trip
16 Day Hidden Galapagos & Peru with Tauck
Tour + Cruise

16 Days Lima to Guayaquil or Lima to Quito
Operated By: Tauck
Ships: Silver Origin
Departures: Sep 2026 to Oct 2027
Visit: Peru, Ecuador, Galapagos
Inside
-
Oceanview
-
Balcony
$16,990
Suite
$29,235
From
US$16,990
Per Person
View Trip
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