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South America Luxury Cruises

Explore the best luxury cruises around South America. Choose from 134 unique cruise itineraries with 160 past traveler reviews from 10 leading cruise lines. January is the most popular month to join a luxury cruise around South America with 253 departures starting between April 2026 and February 2029.
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177 Days
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134 Cruises (253 Cruise Departures)
27 Day Brazil Intensive Cruise: Sao Paulo, Rio De Janiero & Salvador with Azamara Cruises
Cruise
 (5)

27 Days (26 Nights) Buenos Aires to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 16 February 2028
Visit: Argentina, Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Inside
$8,829
Oceanview
$10,399
Balcony
$12,569
Suite
$18,289
From
US$8,829
Per Person
View Trip
11 Day Chile Intensive Cruise: Puerto Montt, Castro & Punta Arenas with Azamara Cruises
Cruise
 (5)

11 Days (10 Nights) Valparaiso to Ushuaia
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina
Azamara Always Included
Inside
$3,249
Oceanview
$3,809
Balcony
$4,669
Suite
$7,169
From
US$3,249
Per Person
View Trip
7 Day Ocean Voyage: Ushuaia - Buenos Aires with Ponant
Cruise
 (2)

7 Days (6 Nights) Ushuaia to Buenos Aires
Cruise Line: Ponant
Ship: Le Boreal
Departure: 12 March 2028
Visit: Argentina
Inside
-
Oceanview
$1,950
Balcony
$2,080
Suite
$3,040
From
US$1,950
Per Person
View Trip
22 Day Treasures of South America with Chilean Fjords - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

22 Days Santiago to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 04 November 2026
Trip Styles: Coach, Cruise, Scenic
Visit: Chile, Argentina, Brazil
Inside
-
Oceanview
-
Balcony
$26,680
Suite
-
From
US$26,680
Per Person
View Trip
15 Day Brazil Intensive Cruise: Salvador, Natal & Belem with Azamara Cruises
Cruise
 (5)

15 Days (14 Nights) Rio de Janeiro to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 28 February 2028
Visit: Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Inside
$4,679
Oceanview
$5,509
Balcony
$6,639
Suite
$9,739
From
US$4,679
Per Person
View Trip
21 Day Bridgetown to Rio De Janeiro with Silversea
Cruise
 (1)

21 Days (20 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Silversea
Ship: Silver Nova
Departure: 18 January 2027
Visit: Barbados, Brazil
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$25,800
From
US$25,800
Save 3,500
Per Person
View Trip
14 Day Ancient Kingdoms and Natural Treasures: Panama to Chile with Scenic
New ReleaseCruise

14 Days (13 Nights) Panama City to Santiago
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 31 October 2027
Visit: Panama, Colombia, Ecuador, Peru, Chile
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,819
Suite
$16,648
From
US$12,819
Save 2,176
Per Person
View Trip
12 Day Wellness Retreat: Barbados to Rio de Janeiro with Scenic
New ReleaseCruise

12 Days (11 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 23 October 2027
Visit: Barbados, Brazil
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,400
Suite
$8,469
From
US$5,400
Save 2,195
Per Person
View Trip
11 Day Panama, Ecuadaor & Peru Cruise: Panama City, Manta & Lima (Callao) with Azamara Cruises
Cruise
 (5)

11 Days (10 Nights) Panama City to Valparaiso
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 14 January 2028
Visit: Panama, Ecuador, Peru, Chile
Azamara Always Included
Inside
$3,239
Oceanview
$3,799
Balcony
$4,669
Suite
$6,839
From
US$3,239
Per Person
View Trip
8 Day Galapagos: Wildlife Wonderland with Tauck
Tour + Cruise

8 Days Quito to Guayaquil
Operated By: Tauck
Departures: Jun 2026 to Dec 2026
Visit: Ecuador, Galapagos
From
US$6,690
Per Person
View Trip
15 Day The Best of Chilean Fjords with Ponant
Cruise

15 Days (14 Nights) Valparaiso to Buenos Aires
Cruise Line: Ponant
Ships: L'Austral, Le Lyrial
Departures: Nov 2026 to Nov 2026
Visit: Chile, Argentina
Inside
-
Oceanview
-
Balcony
$13,000
Suite
$24,410
From
US$13,000
Per Person
View Trip
13 Day Bossa Nova Reverie with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 07 March 2027
Visit: Argentina, Uruguay, Brazil
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$3,849
Oceanview
$4,199
Balcony
-
Suite
-
From
US$3,849
Save 3,849
Per Person
View Trip
15 Day San Cristobal to San Cristobal with Silversea
Cruise

15 Days (14 Nights) Quito to Quito
Cruise Line: Silversea
Ship: Silver Origin
Departure: 29 August 2026
Visit: Galapagos, Ecuador
All-Inclusive Plus Fare
Inside
-
Oceanview
-
Balcony
$21,400
Suite
$38,300
From
US$21,400
Per Person
View Trip
13 Day Brazil Intensive Cruise: Sao Paulo, Poto Belo & Rio De Janeiro with Azamara Cruises
Cruise
 (5)

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 16 February 2028
Visit: Argentina, Uruguay, Brazil
Azamara Always Included
Inside
$4,239
Oceanview
$4,999
Balcony
$5,989
Suite
$8,639
From
US$4,239
Per Person
View Trip
10 Day Wellness Retreat - Panama City to Valparaiso with Scenic
New ReleaseCruise

10 Days (9 Nights) Panama City to Santiago
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 26 October 2026
Visit: Panama, Chile
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,494
Suite
$7,789
From
US$5,494
Save 2,351
Per Person
View Trip
11 Day Emblematic South American Shores and Cities with Ponant
Cruise

11 Days (10 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Ponant
Ship: L'Austral
Departure: 16 March 2027
Visit: Argentina, Uruguay, Brazil
Inside
-
Oceanview
-
Balcony
$9,290
Suite
$25,850
From
US$9,290
Per Person
View Trip
57 Day South America Discovery From Fort Lauderdale with Cunard
Cruise

57 Days (56 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Cunard
Ship: Queen Anne
Departure: 22 January 2027
Visit: USA, Turks and Caicos Islands, Barbados, Brazil (+7 more), Uruguay, Argentina, Chile, Peru, Ecuador, Panama, Aruba
Bonus Onboard Credit
Inside
$11,099
Oceanview
$14,809
Balcony
$15,499
Suite
$35,199
From
US$11,099
Per Person
View Trip
14 Day Chilean Fjords & The Glaciers of The Beagle Channel with Scenic
Cruise

14 Days (13 Nights) Buenos Aires to Santiago
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 08 March 2027
Visit: Chile, Argentina
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,529
Suite
$23,332
From
US$15,529
Save 3,901
Per Person
View Trip
13 Day Chairman’s Voyage: Chilean Fjords & The Glaciers of The Beagle Channel with Scenic
Cruise

13 Days (12 Nights) Santiago to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 13 November 2027
Visit: Chile, Argentina
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$21,258
Suite
$29,067
From
US$21,258
Save 2,517
Per Person
View Trip
22 Day Patagonian Panorama with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Lima to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 03 January 2027
Visit: Peru, Chile, Argentina, Falkland Islands, Uruguay
Your World Inclusions
Exclusive Savings
Inside
$5,567
Oceanview
$5,992
Balcony
-
Suite
-
From
US$5,567
Save 7,531
Per Person
View Trip
13 Day Buenos Aires to Rio De Janeiro with Silversea
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Silversea
Ship: Silver Ray
Departure: 17 February 2028
Visit: Argentina, Uruguay, Brazil
All-Inclusive Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,900
Suite
$19,800
From
US$11,900
Save 2,500
Per Person
View Trip
12 Day Nights Of Samba & Tango with Regent Seven Seas
Cruise

12 Days (11 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 22 January 2027
Visit: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,199
Suite
$12,999
From
US$12,199
Save 12,199
Per Person
View Trip
11 Day Rio De Janeiro to Buenos Aires with Silversea
Cruise
 (1)

11 Days (10 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Silversea
Ship: Silver Nova
Departure: 07 February 2027
Visit: Brazil, Uruguay, Argentina
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$12,100
Suite
-
From
US$12,100
Per Person
View Trip
24 Day Brazil & Argentina Cruise: Rio De Janeiro, Salvador & Buenos Aires with Azamara Cruises
Cruise
 (3)

24 Days (23 Nights) Bridgetown to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 25 January 2027
Visit: Barbados, Trinidad and Tobago, French Guiana, Brazil, Uruguay, Argentina
Azamara Circle Member - Quarterly Saving
Azamara Always Included
Inside
$7,659
Oceanview
$8,569
Balcony
$10,739
Suite
$15,359
From
US$7,659
Per Person
View Trip
11 Day From Panama’s Wild Beauty to Peruvian Shores with Ponant
Cruise

11 Days (10 Nights) Colon to Lima
Cruise Line: Ponant
Ship: L'Austral
Departure: 20 October 2026
Visit: Panama, Peru
Inside
-
Oceanview
$6,250
Balcony
$6,760
Suite
$10,670
From
US$6,250
Per Person
View Trip
18 Day Fjords & Glaciers of Southern Chile & Patagonia with Scenic
New ReleaseCruise

18 Days (17 Nights) Buenos Aires to Buenos Aires
Cruise Line: Scenic
Ships: Scenic Eclipse I, Scenic Ikon
Departures: Feb 2027 to Feb 2029
Visit: Argentina, Chile, Uruguay
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,108
Suite
$28,669
From
US$13,108
Save 3,517
Per Person
View Trip
15 Day Chilean Heritage & Fjords with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Lima to Punta Arenas
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 19 January 2028
Visit: Peru, Chile
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$4,549
Oceanview
$4,799
Balcony
$6,299
Suite
$8,899
From
US$4,549
Save 4,549
Per Person
View Trip
21 Day Rio De Janeiro To San Antonio with Cunard
Cruise

21 Days (20 Nights) Rio de Janeiro to Santiago
Cruise Line: Cunard
Ship: Queen Anne
Departure: 08 February 2027
Visit: Brazil, Uruguay, Argentina, Chile
Bonus Onboard Credit
Inside
$4,899
Oceanview
$7,199
Balcony
$7,999
Suite
-
From
US$4,899
Per Person
View Trip
12 Day Rhythms of the Brazilian Coastline with Scenic
New ReleaseCruise

12 Days (11 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 03 November 2027
Visit: Brazil, Uruguay, Argentina
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$10,751
Suite
$12,978
From
US$10,751
Save 2,679
Per Person
View Trip
22 Day Lima (Callao) to Buenos Aires with Silversea
Cruise

22 Days (21 Nights) Lima to Buenos Aires
Cruise Line: Silversea
Ship: Silver Ray
Departure: 27 January 2028
Visit: Peru, Chile, Argentina, Falkland Islands
All-Inclusive Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$16,800
Suite
$28,000
From
US$16,800
Save 3,500
Per Person
View Trip
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