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South America Luxury Cruises

Explore the best luxury cruises around South America. Choose from 135 unique cruise itineraries from 10 leading cruise lines. January is the most popular month to join a luxury cruise around South America with 271 departures starting between January 2026 and March 2028.
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177 Days
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135 Cruises (271 Cruise Departures)
15 Day Cartagena to Valparaiso with Silversea
Cruise

15 Days (14 Nights) Cartagena to Valparaiso
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 15 January 2028
Visit: Colombia, Panama, Ecuador, Peru, Chile
All-Inclusive Fare
Inside
-
Oceanview
$8,000
Balcony
$9,600
Suite
-
From
US$8,000
Per Person
View Trip
17 Day Patagonia & the Chilean Fjords with Scenic
New ReleaseCruise

17 Days (16 Nights) Buenos Aires to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 14 November 2027
Visit: Argentina, Uruguay, Chile
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,532
Suite
$18,879
From
US$15,532
Save 19,458
Per Person
View Trip
13 Day Buenos Aires to Rio De Janeiro with Silversea
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 15 February 2028
Visit: Argentina, Uruguay, Brazil
All-Inclusive Fare
Inside
-
Oceanview
$12,900
Balcony
$13,900
Suite
$36,200
From
US$12,900
Per Person
View Trip
13 Day Rio De Janeiro to Buenos Aires with Silversea
Cruise

13 Days (12 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 14 February 2026
Visit: Brazil, Uruguay, Argentina
Last Minute Fare
All-Inclusive Fare
Inside
-
Oceanview
$5,700
Balcony
$7,400
Suite
$13,920
From
US$5,700
Per Person
View Trip
19 Day Around Cape Horn with Oceania Cruises
Cruise

19 Days (18 Nights) Buenos Aires to Lima
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 03 February 2026
Visit: Argentina, Uruguay, Falkland Islands, Chile, Peru
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,035
Suite
$18,481
From
US$7,035
Save 7,363
Per Person
View Trip
13 Day Bossa Nova Reverie with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 07 March 2027
Visit: Argentina, Uruguay, Brazil
Your World Inclusions
Upgrade Your Experience
Exclusive Savings
Inside
$3,484
Oceanview
$3,727
Balcony
$5,133
Suite
$7,461
From
US$3,484
Save 3,614
Per Person
View Trip
15 Day Chilean Heritage & Fjords with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Lima to Punta Arenas
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 19 January 2028
Visit: Peru, Chile
Your World Inclusions
Black Friday Sale + Your World Included
Exclusive Savings
Inside
$4,305
Oceanview
$4,693
Balcony
$6,148
Suite
$8,670
From
US$4,305
Save 4,493
Per Person
View Trip
22 Day Patagonian Panorama with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Lima to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 03 January 2027
Visit: Peru, Chile, Argentina, Falkland Islands, Uruguay
Upgrade Your Experience
Your World Inclusions
Exclusive Savings
Inside
$5,642
Oceanview
$6,079
Balcony
$7,999
Suite
$11,142
From
US$5,642
Save 7,156
Per Person
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Jan 2026 to Mar 2028
Visit: Ecuador, Galapagos
Last Minute Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,160
Suite
$17,280
From
US$11,160
Save 1,600
Per Person
View Trip
15 Day Brazil Intensive Cruise: Salvador, Natal & Belem with Azamara Cruises
Cruise
 (4)

15 Days (14 Nights) Rio de Janeiro to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 28 February 2028
Visit: Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Exclusive Savings
Inside
$4,576
Oceanview
$5,381
Balcony
$6,478
Suite
$9,485
From
US$4,576
Save 103
Per Person
View Trip
21 Day Rio De Janeiro To San Antonio with Cunard
Cruise

21 Days (20 Nights) Rio de Janeiro to Santiago
Cruise Line: Cunard
Ship: Queen Anne
Departure: 08 February 2027
Visit: Brazil, Uruguay, Argentina, Chile
Inside
$4,699
Oceanview
$7,138
Balcony
$8,029
Suite
-
From
US$4,699
Per Person
View Trip
14 Day Chilean Fjords & The Glaciers of The Beagle Channel with Scenic
Cruise

14 Days (13 Nights) Buenos Aires to Santiago
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 08 March 2027
Visit: Chile, Argentina
Wave Offer
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,012
Suite
$25,331
From
US$13,012
Save 20,708
Per Person
View Trip
13 Day Brazil Intensive Cruise: Sao Paulo, Poto Belo & Rio De Janeiro with Azamara Cruises
Cruise
 (4)

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 16 February 2028
Visit: Argentina, Uruguay, Brazil
Azamara Always Included
Exclusive Savings
Inside
$4,149
Oceanview
$4,886
Balcony
$5,847
Suite
$8,417
From
US$4,149
Save 90
Per Person
View Trip
15 Day San Cristóbal to San Cristóbal with Silversea
Cruise

15 Days (14 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Jun 2026 to Mar 2027
Visit: Ecuador, Galapagos
All-Inclusive Plus Fare
Inside
-
Oceanview
-
Balcony
$21,400
Suite
$45,000
From
US$21,400
Per Person
View Trip
10 Day Wellness Retreat - Panama City to Valparaiso with Scenic
New ReleaseCruise

10 Days (9 Nights) Panama City to Santiago
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 26 October 2026
Visit: Panama, Chile
Wave Offer
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,157
Suite
$8,970
From
US$6,157
Save 12,833
Per Person
View Trip
7 Day Ecuador and Galápagos Islands Cruise with APT
New ReleaseTour + Cruise

7 Days Guayaquil to Guayaquil
Operated By: APT
Departure: 26 August 2026
Visit: Ecuador, Galapagos
Exclusive Savings
From
US$14,697
Save 298
Per Person
View Trip
13 Day Chilean Fjords & The Glaciers of The Beagle Channel with Scenic
Cruise

13 Days (12 Nights) Santiago to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 04 November 2026
Visit: Chile, Argentina
Wave Offer
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,686
Suite
$19,857
From
US$15,686
Save 22,704
Per Person
View Trip
11 Day Chile Intensive Cruise: Puerto Montt, Castro & Punta Arenas with Azamara Cruises
Cruise
 (4)

11 Days (10 Nights) Valparaiso to Ushuaia
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina
Azamara Always Included
Exclusive Savings
Inside
$3,174
Oceanview
$3,717
Balcony
$4,551
Suite
$6,976
From
US$3,174
Save 75
Per Person
View Trip
13 Day Buenos Aires to Rio De Janeiro with Silversea
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Silversea
Ship: Silver Ray
Departure: 17 February 2028
Visit: Argentina, Uruguay, Brazil
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,440
Suite
$14,470
From
US$11,440
Save 2,860
Per Person
View Trip
11 Day Panama, Ecuadaor & Peru Cruise: Panama City, Manta & Lima (Callao) with Azamara Cruises
Cruise
 (4)

11 Days (10 Nights) Panama City to Valparaiso
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 14 January 2028
Visit: Panama, Ecuador, Peru, Chile
Azamara Always Included
Exclusive Savings
Inside
$3,165
Oceanview
$3,708
Balcony
$4,552
Suite
$6,657
From
US$3,165
Save 74
Per Person
View Trip
12 Day Nights Of Samba & Tango with Regent Seven Seas
Cruise

12 Days (11 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 22 January 2027
Visit: Brazil, Uruguay, Argentina
Upgrade Your Horizon
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$12,434
Suite
$12,973
From
US$23,948
Save 450
Per Person
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departure: 19 September 2026
Visit: Galapagos, Ecuador
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,280
Suite
$18,840
From
US$11,280
Save 2,820
Per Person
View Trip
15 Day San Cristobal to San Cristobal with Silversea
Cruise

15 Days (14 Nights) Quito to Quito
Cruise Line: Silversea
Ship: Silver Origin
Departures: Aug 2026 to Dec 2026
Visit: Galapagos, Ecuador
All-Inclusive Plus Fare
Inside
-
Oceanview
-
Balcony
$21,400
Suite
$38,300
From
US$21,400
Per Person
View Trip
14 Day Chile, Peru & Panama Voyage with Azamara Cruises
Cruise
 (4)

14 Days (13 Nights) San Antonio to Panama City
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 02 March 2026
Visit: Chile, Peru, Panama
Azamara Always Included
Inside
-
Oceanview
$2,229
Balcony
$2,749
Suite
$4,640
From
US$2,229
Per Person
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) San Cristobal Island to San Cristobal Island
Cruise Line: Silversea
Ship: Silver Origin
Departures: Feb 2026 to Mar 2026
Visit: Ecuador, Galapagos
Last Minute Fare
All-Inclusive Plus Fare
Inside
-
Oceanview
-
Balcony
$11,600
Suite
$24,720
From
US$11,600
Per Person
View Trip
27 Day Brazil Intensive Cruise: Sao Paulo, Rio De Janiero & Salvador with Azamara Cruises
Cruise
 (4)

27 Days (26 Nights) Buenos Aires to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 16 February 2028
Visit: Argentina, Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Exclusive Savings
Inside
$8,636
Oceanview
$10,159
Balcony
$12,264
Suite
$17,812
From
US$8,636
Save 193
Per Person
View Trip
24 Day Brazil & Argentina Cruise: Rio De Janeiro, Salvador & Buenos Aires with Azamara Cruises
Cruise
 (3)

24 Days (23 Nights) Bridgetown to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 25 January 2027
Visit: Barbados, Trinidad and Tobago, French Guiana, Brazil, Uruguay, Argentina
Azamara Always Included
Exclusive Savings
Inside
$7,492
Oceanview
$8,375
Balcony
$10,480
Suite
$14,961
From
US$7,492
Save 167
Per Person
View Trip
12 Day Wellness Retreat: Barbados to Rio de Janeiro with Scenic
New ReleaseCruise

12 Days (11 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 23 October 2027
Visit: Barbados, Brazil
Early Booking Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,533
Suite
$8,376
From
US$6,533
Save 10,057
Per Person
View Trip
26 Day Peru, Amazon & the Chilean Fjords Expedition - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

26 Days Lima to Buenos Aires
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 22 October 2026
Trip Styles: Coach, Cruise, Wildlife, Scenic
Visit: Peru, Chile, Argentina
Fly Free Premium Economy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$27,158
Suite
$33,269
From
US$27,158
Save 22,997
Per Person
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Apr 2026 to Mar 2028
Visit: Ecuador, Galapagos
Last Minute Fare
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,200
Suite
$17,930
From
US$11,200
Save 2,800
Per Person
View Trip
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