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South America Luxury Cruises

Explore the best luxury cruises around South America. Choose from 122 unique cruise itineraries from 8 leading cruise lines. January and March are the most popular months to join a luxury cruise around South America with 253 departures starting between April 2024 and March 2026.
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86 Days
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122 Cruises (253 Cruise Departures)
20 Day Falklands, South Georgia & Valdes Peninsula: In The Heart Of The Wilderness with Ponant
Cruise
 (1)

20 Days (19 Nights) Buenos Aires to Buenos Aires
Cruise Line: Ponant
Ship: Le Boreal
Departure: 11 March 2025
Countries Visited: Argentina, Falkland Islands, South Georgia Island
Exclusive Savings
INSIDE
-
OCEANVIEW
$17,393
BALCONY
$19,402
SUITE
$28,614
Save 327
From 17,393
View Trip
23 Day Barbados To Brazil & Buenos Aires Voyage with Azamara Cruises
Cruise
 (1)

23 Days (22 Nights) Bridgetown to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 17 January 2026
Countries Visited: Barbados, Trinidad and Tobago, French Guiana, Brazil (+2 more), Uruguay, Argentina
INSIDE
$8,377
OCEANVIEW
$10,218
BALCONY
$12,057
SUITE
$14,011
From 8,377
View Trip
14 Day Chile, Peru & Panama Voyage with Azamara Cruises
Cruise
 (1)

14 Days (13 Nights) San Antonio to Panama City
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 02 March 2026
Countries Visited: Chile, Peru, Panama
INSIDE
$5,330
OCEANVIEW
$6,365
BALCONY
$7,515
SUITE
$8,780
From 5,330
View Trip
10 Day Ocean Voyage: Hanga Roa - Ushuaia with Ponant
Cruise
 (1)

10 Days (9 Nights) Hanga Roa to Ushuaia
Cruise Line: Ponant
Ship: Le Boreal
Departure: 05 November 2024
Countries Visited: Easter Island, Argentina
Exclusive Savings
INSIDE
-
OCEANVIEW
$3,296
BALCONY
$3,551
SUITE
$5,315
Save 54
From 3,296
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departure: 18 October 2025
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$17,919
SUITE
$40,095
From 17,919
View Trip
13 Day Buenos Aires to Rio De Janeiro with Silversea
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 16 December 2025
Countries Visited: Argentina, Uruguay, Brazil
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$11,187
BALCONY
$12,276
SUITE
$20,889
From 11,187
View Trip
12 Day Wonders of the Galápagos & Machu Picchu: Eastern Islands Route with Abercrombie & Kent
New ReleaseTour + Cruise

12 Days Guayaquil to Lima
Operated By: Abercrombie & Kent
Departures: Apr 2025 to Oct 2025
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos, Peru
From 27,245
View Trip
11 Day Buenos Aires to Rio De Janeiro with Silversea
Cruise

11 Days (10 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Silversea
Ship: Silver Ray
Departure: 21 February 2025
Countries Visited: Argentina, Brazil, Uruguay
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$15,246
From 15,246
View Trip
12 Day Crossing the Equator: Barbados to Brazil with Scenic
Cruise

12 Days (11 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 November 2024
Countries Visited: Brazil, French Guiana, Barbados
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$6,579
SUITE
$10,207
Save 8,566
From 6,579
View Trip
15 Day Season Of Samba with Regent Seven Seas
Cruise

15 Days (14 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 03 December 2025
Countries Visited: Barbados, Saint Vincent, Trinidad and Tobago, French Guiana (+1 more), Brazil
Land Package Credit
INSIDE
-
OCEANVIEW
-
BALCONY
$13,761
SUITE
$15,533
Save 8,269
From 13,761
View Trip
8 Day San Cristóbal, Galapagos to San Cristóbal, Galapagos with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Jul 2024 to Mar 2026
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$17,226
SUITE
$25,245
From 17,226
View Trip
13 Day Ushuaia to Valparaiso with Silversea
Cruise

13 Days (12 Nights) Ushuaia to Valparaiso
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 19 March 2025
Countries Visited: Argentina, Chile
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
$9,405
BALCONY
$12,870
SUITE
$19,107
From 9,405
View Trip
15 Day Amazon Delta & Coast Of Brazil with Seabourn
Cruise

15 Days (14 Nights) Manaus to Rio de Janeiro
Cruise Line: Seabourn
Ship: Venture
Departure: 21 October 2024
Countries Visited: Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$15,065
SUITE
$22,292
From 15,065
View Trip
31 Day South America Connoisseur with Oceania Cruises
Cruise

31 Days (30 Nights) San Antonio to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 06 March 2025
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay (+1 more), Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$16,732
SUITE
$22,662
Save 2,128
From 16,732
View Trip
15 Day The Best of Chilean Fjords with Ponant
Cruise

15 Days (14 Nights) Valparaiso to Buenos Aires
Cruise Line: Ponant
Ships: Le Boreal, Le Lyrial
Departures: Oct 2024 to Nov 2025
Countries Visited: Chile, Argentina
Exclusive Savings
INSIDE
-
OCEANVIEW
$11,206
BALCONY
$12,000
SUITE
$19,438
Save 229
From 11,206
View Trip
13 Day Bounty Of Brazil with Oceania Cruises
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 10 January 2026
Countries Visited: Argentina, Uruguay, Brazil
Exclusive Deal
INSIDE
$6,185
OCEANVIEW
$6,947
BALCONY
$7,709
SUITE
$10,719
Save 2,045
From 6,185
View Trip
17 Day Lima to Fort Lauderdale with Silversea
Cruise

17 Days (16 Nights) Lima to Fort Lauderdale
Cruise Line: Silversea
Ship: Silver Ray
Departure: 04 January 2025
Countries Visited: Aruba, Colombia, Ecuador, Panama (+2 more), Peru, USA
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$12,870
From 12,870
View Trip
15 Day Wild Guianas To The Amazon Basin with Seabourn
Cruise

15 Days (14 Nights) Bridgetown to Manaus
Cruise Line: Seabourn
Ship: Venture
Departure: 07 October 2024
Countries Visited: Barbados, Trinidad and Tobago, French Guiana, Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$21,595
SUITE
$40,999
From 21,595
View Trip
11 Day Brazilian Brilliance with Oceania Cruises
Cruise

11 Days (10 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 March 2026
Countries Visited: Argentina, Uruguay, Brazil
Exclusive Deal
INSIDE
$5,124
OCEANVIEW
$5,807
BALCONY
$6,421
SUITE
$8,955
Save 2,036
From 5,124
View Trip
10 Day Heart Of The Amazon with Seabourn
Cruise

10 Days (9 Nights) Manaus to Manaus
Cruise Line: Seabourn
Ship: Venture
Departure: 12 October 2025
Countries Visited: Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$17,870
SUITE
$34,502
From 17,870
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) San Cristobal Island to San Cristobal Island
Cruise Line: Silversea
Ship: Silver Origin
Departure: 21 March 2026
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$20,592
SUITE
$37,323
From 20,592
View Trip
12 Day Wonders of the Galápagos & Machu Picchu: Northern Islands Route with Abercrombie & Kent
New ReleaseTour + Cruise

12 Days Guayaquil to Lima
Operated By: Abercrombie & Kent
Departures: Feb 2025 to Nov 2025
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos, Peru
From 26,465
View Trip
8 Day San Cristóbal, Galapagos to San Cristóbal, Galapagos with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Apr 2025 to Feb 2026
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$17,919
SUITE
$26,334
From 17,919
View Trip
15 Day Peru & the Galapagos Islands with Tauck
Tour + Cruise

15 Days Lima to Guayaquil
Operated By: Tauck
Departures: Apr 2024 to Oct 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
From 19,700
View Trip
12 Day Lautoka to Tahiti with Silversea
Cruise

12 Days (11 Nights) Lautoka to Tahiti
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 29 September 2025
Countries Visited: Fiji, Cook Islands, Tonga, French Polynesia
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$22,473
BALCONY
$25,641
SUITE
$38,709
From 22,473
View Trip
13 Day Ushuaia to Valparaiso with Silversea
Cruise

13 Days (12 Nights) Ushuaia to Valparaiso
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 16 March 2026
Countries Visited: Argentina, Chile
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
$10,692
BALCONY
$12,771
SUITE
$28,611
From 10,692
View Trip
13 Day Amazon Delta & Coast Of Brazil with Seabourn
Cruise

13 Days (12 Nights) Manaus to Rio de Janeiro
Cruise Line: Seabourn
Ship: Venture
Departure: 30 October 2025
Countries Visited: Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$13,496
SUITE
$20,129
From 13,496
View Trip
10 Day Heart Of The Amazon with Seabourn
Cruise

10 Days (9 Nights) Manaus to Manaus
Cruise Line: Seabourn
Ship: Venture
Departure: 21 October 2025
Countries Visited: Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$17,870
SUITE
$34,502
From 17,870
View Trip
22 Day The Complete Amazon Experience & Coast Of Brazil with Seabourn
Cruise

22 Days (21 Nights) Manaus to Rio de Janeiro
Cruise Line: Seabourn
Ship: Venture
Departure: 21 October 2025
Countries Visited: Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$28,297
SUITE
$49,186
From 28,297
View Trip
9 Day Lima to Valparaiso with Silversea
Cruise

9 Days (8 Nights) Lima to Valparaiso
Cruise Line: Silversea
Ship: Silver Ray
Departure: 01 February 2025
Countries Visited: Chile, Peru
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$7,969
From 7,969
View Trip
Results: 1-30 of 122

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