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South America Luxury Cruises

Explore the best luxury cruises around South America. Choose from 134 unique cruise itineraries with 160 past traveler reviews from 10 leading cruise lines. January is the most popular month to join a luxury cruise around South America with 253 departures starting between April 2026 and February 2029.
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134 Cruises (253 Cruise Departures)
27 Day Puerto Williams to Valparaiso with Silversea
Cruise

27 Days (26 Nights) Puerto Williams to Valparaiso
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 12 February 2027
Visit: Chile, South Georgia Island, Antarctica, Argentina
All-Inclusive Plus Fare
Inside
-
Oceanview
-
Balcony
$28,100
Suite
$79,900
From
US$28,100
Per Person
View Trip
29 Day Ultimate Antarctica & the Fjords of Southern Chile with Scenic
New ReleaseCruise

29 Days (28 Nights) Buenos Aires to Buenos Aires
Cruise Line: Scenic
Ships: Scenic Eclipse I, Scenic Ikon
Departures: Feb 2027 to Feb 2029
Visit: Argentina, Antarctica, Chile, Uruguay
Preferred Fare + Bonus Savings
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$35,366
Suite
$103,665
From
US$35,366
Save 6,948
Per Person
View Trip
22 Day Southern Fjords & Glaciers with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Valparaiso to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 14 February 2027
Visit: Chile, Argentina, Antarctica, Falkland Islands
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$6,599
Oceanview
$6,999
Balcony
$9,599
Suite
$13,099
From
US$6,599
Save 6,599
Per Person
View Trip
31 Day Verdant Empire with Regent Seven Seas
Cruise

31 Days (30 Nights) Lima to Rio de Janeiro
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 27 January 2028
Visit: Peru, Chile, Antarctica, Falkland Islands, Argentina, Uruguay, Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$32,399
From
US$32,399
Save 32,399
Per Person
View Trip
19 Day Journey to Austral Lands and Valdes Peninsula with Ponant
Cruise

19 Days (18 Nights) Buenos Aires to Buenos Aires
Cruise Line: Ponant
Ships: L'Austral, Le Boreal
Departures: Feb 2027 to Mar 2027
Visit: Argentina, Antarctica, South Georgia Island, Falkland Islands
Inside
-
Oceanview
$21,040
Balcony
$22,550
Suite
$35,310
From
US$21,040
Per Person
View Trip
19 Day Antarctic Encounter with Regent Seven Seas
Cruise

19 Days (18 Nights) Buenos Aires to Lima
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 20 February 2027
Visit: Argentina, Falkland Islands, Antarctica, Chile, Peru
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,099
Suite
$18,999
From
US$17,099
Save 17,099
Per Person
View Trip
37 Day Antarctic Voyage with South America and Galápagos Islands with APT
New ReleaseTour + Cruise

37 Days Guayaquil to Rio de Janeiro
Operated By: APT
Ship: Seabourn Venture
Departure: 23 January 2027
Trip Styles: Cruise, Wildlife, Scenic
Visit: Ecuador, Galapagos, Peru, Argentina, Antarctica, Brazil
Inside
-
Oceanview
-
Balcony
$42,795
Suite
$45,395
From
US$42,795
Per Person
View Trip
21 Day Valparaiso to Puerto Williams with Silversea
Cruise

21 Days (20 Nights) Valparaiso to Santiago
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 15 November 2027
Visit: Chile, Argentina, Antarctica
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$31,500
Suite
$43,100
From
US$31,500
Save 3,500
Per Person
View Trip
20 Day Easter & Pitcairn Islands: Marooned, Moai & Mutineers with Seabourn
Cruise

20 Days (19 Nights) Tahiti to Santiago
Cruise Line: Seabourn
Ship: Seabourn Pursuit
Departure: 16 October 2026
Visit: French Polynesia, Pitcairn Islands, Easter Island, Chile
Yours to Explore
Inside
-
Oceanview
-
Balcony
$17,499
Suite
$22,999
From
US$17,499
Per Person
View Trip
36 Day World Cruise: Panama Canal Crossing & Polynesia with Seabourn
Cruise
 (1)

36 Days (35 Nights) Miami to Tahiti
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 January 2027
Visit: USA, Panama, Ecuador, Peru, Chile, Easter Island, French Polynesia
Yours to Explore
Inside
-
Oceanview
$20,099
Balcony
$22,599
Suite
$45,099
From
US$20,099
Per Person
View Trip
37 Day San Antonio To Hamburg with Cunard
Cruise

37 Days (36 Nights) Santiago to Hamburg
Cruise Line: Cunard
Ship: Queen Anne
Departure: 28 February 2027
Visit: Chile, Peru, Ecuador, Panama (+6 more), Aruba, USA, Portugal, England, Belgium, Germany
Bonus Onboard Credit
Inside
$5,929
Oceanview
$8,189
Balcony
$9,319
Suite
$20,069
From
US$5,929
Per Person
View Trip
20 Day Panama, Peru & Chile Cruise: Panama Canal, Lima & Coquimbo with Azamara Cruises
Cruise
 (5)

20 Days (19 Nights) Miami to Valparaiso
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+5 more), Costa Rica, Panama, Ecuador, Peru, Chile
Azamara Always Included
Inside
$6,249
Oceanview
$7,069
Balcony
$8,579
Suite
$12,279
From
US$6,249
Per Person
View Trip
19 Day Valparaiso to Miami with Silversea
Cruise
 (1)

19 Days (18 Nights) Valparaiso to Miami
Cruise Line: Silversea
Ship: Silver Nova
Departure: 05 March 2027
Visit: Chile, Peru, Ecuador, Panama, Mexico, USA
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$13,200
Suite
$18,700
From
US$13,200
Save 3,500
Per Person
View Trip
20 Day Southern America & Panama Canal Cruise: Lima, Panama City & Cozumel with Azamara Cruises
Cruise
 (3)

20 Days (19 Nights) Santiago to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 10 March 2027
Visit: Chile, Peru, Panama, Costa Rica, Colombia, Mexico, USA
Azamara Circle Member - Quarterly Saving
Azamara Always Included
Inside
$6,529
Oceanview
$7,339
Balcony
$7,879
Suite
$13,089
From
US$6,529
Per Person
View Trip
13 Day Miami, Fl to Lima (Callao) with Silversea
Cruise

13 Days (12 Nights) Miami to Lima
Cruise Line: Silversea
Ship: Silver Ray
Departure: 15 January 2028
Visit: USA, Mexico, Costa Rica, Panama, Ecuador, Peru
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,900
Suite
$14,700
From
US$8,900
Save 2,500
Per Person
View Trip
17 Day Machu Picchu & Mayan Ruins with Regent Seven Seas
Cruise

17 Days (16 Nights) Lima to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 10 March 2027
Visit: Peru, Ecuador, Costa Rica, Panama (+4 more), Honduras, Belize, Mexico, USA
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,399
Suite
$16,899
From
US$15,399
Save 15,399
Per Person
View Trip
91 Day South America Discovery with Cunard
Cruise

91 Days (90 Nights) Hamburg to Hamburg
Cruise Line: Cunard
Ship: Queen Anne
Departure: 05 January 2027
Visit: Germany, Holland, Belgium, England (+13 more), Bermuda, USA, Turks and Caicos Islands, Barbados, Brazil, Uruguay, Argentina, Chile, Peru, Ecuador, Panama, Aruba, Portugal
Bonus Onboard Credit
Inside
$14,289
Oceanview
$19,779
Balcony
$21,799
Suite
$42,999
From
US$14,289
Per Person
View Trip
41 Day Amazon & Tropical Isles with Oceania Cruises
Cruise
 (1)

41 Days (40 Nights) Lisbon to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 09 November 2026
Visit: Portugal, Spain, Puerto Rico, Bahamas (+9 more), USA, Virgin Islands, Antigua and Barbuda, Saint Lucia, Trinidad and Tobago, Brazil, Barbados, Dominica, Saint Martin
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
$11,149
Balcony
$16,249
Suite
$40,799
From
US$11,149
Save 11,149
Per Person
View Trip
30 Day Southampton To Rio De Janeiro with Cunard
Cruise

30 Days (29 Nights) London to Rio de Janeiro
Cruise Line: Cunard
Ship: Queen Anne
Departure: 10 January 2027
Visit: England, Bermuda, USA, Turks and Caicos Islands, Barbados, Brazil
Bonus Onboard Credit
Inside
$4,289
Oceanview
$5,909
Balcony
$6,399
Suite
$14,879
From
US$4,289
Per Person
View Trip
83 Day South America Discovery with Cunard
Cruise

83 Days (82 Nights) London to London
Cruise Line: Cunard
Ship: Queen Anne
Departure: 10 January 2027
Visit: England, Bermuda, USA, Turks and Caicos Islands (+10 more), Barbados, Brazil, Uruguay, Argentina, Chile, Peru, Ecuador, Panama, Aruba, Portugal
Bonus Onboard Credit
Inside
$13,249
Oceanview
$18,259
Balcony
$20,219
Suite
$40,029
From
US$13,249
Per Person
View Trip
55 Day Epic Antarctic & Amazon with Oceania Cruises
Cruise
 (1)

55 Days (54 Nights) Valparaiso to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 14 February 2027
Visit: Chile, Argentina, Antarctica, Falkland Islands (+6 more), Uruguay, Brazil, Barbados, Antigua and Barbuda, Virgin Islands, USA
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$15,999
Oceanview
$16,849
Balcony
-
Suite
-
From
US$15,999
Save 15,999
Per Person
View Trip
32 Day South America, Canary Islands, Spain & France with Seabourn
Cruise

32 Days (31 Nights) Rio de Janeiro to Amsterdam
Cruise Line: Seabourn
Ship: Seabourn Venture
Departure: 06 April 2027
Visit: Brazil, Cape Verde, Spain, Morocco, Portugal, France, Holland
Yours to Explore
Inside
-
Oceanview
-
Balcony
-
Suite
$18,699
From
US$18,699
Per Person
View Trip
35 Day Hamburg To Rio De Janeiro with Cunard
Cruise

35 Days (34 Nights) Hamburg to Rio de Janeiro
Cruise Line: Cunard
Ship: Queen Anne
Departure: 05 January 2027
Visit: Germany, Holland, Belgium, England (+5 more), Bermuda, USA, Turks and Caicos Islands, Barbados, Brazil
Bonus Onboard Credit
Inside
$5,369
Oceanview
$7,749
Balcony
$8,769
Suite
$18,599
From
US$5,369
Per Person
View Trip
44 Day Papeete to Puerto Williams with Silversea
Cruise

44 Days (43 Nights) Tahiti to Santiago
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 23 October 2027
Visit: French Polynesia, Pitcairn Islands, Easter Island, Chile, Argentina, Antarctica
All-Inclusive Plus Fare
Inside
-
Oceanview
-
Balcony
$31,500
Suite
$45,000
From
US$31,500
Per Person
View Trip
29 Day Caribbean, Central America & Peru Cruise: Aruba, Miami & Panama Canal with Azamara Cruises
Cruise
 (5)

29 Days (28 Nights) Bridgetown to Valparaiso
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 27 December 2027
Visit: Barbados, Bonaire, Curacao, Aruba (+11 more), Dominican Republic, Bahamas, USA, Mexico, Belize, Honduras, Costa Rica, Panama, Ecuador, Peru, Chile
Azamara Always Included
Inside
$8,779
Oceanview
$10,339
Balcony
$12,599
Suite
$18,419
From
US$8,779
Per Person
View Trip
54 Day Chilean Fjords, Antarctica & South Atlantic Explorer with Seabourn
Cruise
 (1)

54 Days (53 Nights) Valparaiso to Cape Town
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 February 2028
Visit: Chile, Argentina, Antarctica, Falkland Islands (+4 more), Uruguay, Saint Helena, South Africa, Mozambique
Yours to Explore
Inside
-
Oceanview
$35,999
Balcony
$39,999
Suite
-
From
US$35,999
Per Person
View Trip
64 Day World Cruise: Panama Canal, Polynesia & New Zealand with Seabourn
Cruise
 (1)

64 Days (63 Nights) Miami to Sydney
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 January 2027
Visit: USA, Panama, Ecuador, Peru (+6 more), Chile, French Polynesia, Cook Islands, Tonga, New Zealand, Australia
Yours to Explore
Inside
-
Oceanview
$35,299
Balcony
$41,599
Suite
-
From
US$35,299
Per Person
View Trip
83 Day South America, Antarctica, South Atlantic & Africa with Seabourn
Cruise
 (1)

83 Days (82 Nights) Miami to Cape Town
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visit: USA, Panama, Ecuador, Peru (+8 more), Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Saint Helena, South Africa, Mozambique
Yours to Explore
Inside
-
Oceanview
$54,999
Balcony
$61,999
Suite
-
From
US$54,999
Per Person
View Trip
41 Day Buenos Aires To Miami Grand Voyage with Azamara Cruises
Cruise
 (3)

41 Days (40 Nights) Buenos Aires to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 17 February 2027
Visit: Argentina, Uruguay, Falkland Islands, Antarctica (+7 more), Chile, Peru, Panama, Costa Rica, Colombia, Mexico, USA
Azamara Always Included
Inside
$16,979
Oceanview
$16,979
Balcony
$20,529
Suite
$32,239
From
US$16,979
Per Person
View Trip
43 Day Miami To Buenos Aires Grand Voyage with Azamara Cruises
Cruise
 (5)

43 Days (42 Nights) Miami to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+9 more), Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Azamara Always Included
Inside
$14,709
Oceanview
$16,609
Balcony
$20,709
Suite
$29,119
From
US$14,709
Per Person
View Trip
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