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South America Luxury Cruises

Explore the best luxury cruises around South America. Choose from 174 unique cruise itineraries with 159 past traveller reviews from 11 leading cruise lines. January is the most popular month to join a luxury cruise around South America with 279 departures starting between September 2026 and March 2029.
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174 Cruises (279 Departures)
174 Cruises (279 Departures)
Departures
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Duration
6 Days
141 Days
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Price
$2,200pp
$133,895pp
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9 Day Chile & Peru Cruise: Arica, Pisco & Lima with Azamara Cruises
Cruise
 (5)

9 Days (8 Nights) Santiago to Lima
Operator: Azamara
Ship: Azamara Journey
Departure: 10 March 2027
Visits: Chile, Peru
Azamara Always Included
Exclusive Savings
Inside
$2,648
Oceanview
$3,021
Balcony
$3,648
Suite
-
From (Per Person)
A$2,648
Save 41
Per Person
View Trip
19 Day Valparaiso to Miami with Silversea
Cruise
 (1)

19 Days (18 Nights) Valparaiso to Miami
Operator: Silversea
Ship: Silver Nova
Departure: 05 March 2027
Visits: Chile, Peru, Ecuador, Panama, Mexico, USA
Exclusive Savings
Balcony
$17,562
Suite
$31,458
From (Per Person)
A$17,562
Save 8,038
Per Person
View Trip
57 Day Miami To Sydney Grand Voyage with Azamara Cruises
Cruise
 (8)

57 Days (56 Nights) Miami to Sydney
Operator: Azamara
Ship: Azamara Onward
Departure: 05 January 2028
Visits: USA, Aruba, Curacao, Colombia +8 more, Panama, Ecuador, Peru, Chile, Pitcairn Islands, French Polynesia, New Zealand, Australia
Azamara Always Included
Exclusive Savings
Inside
$28,075
Oceanview
$28,726
Balcony
-
Suite
$48,920
From (Per Person)
A$28,075
Save 1,944
Per Person
View Trip
24 Day Brazil & Argentina Cruise: Rio De Janeiro, Salvador & Buenos Aires with Azamara Cruises
Cruise
 (5)

24 Days (23 Nights) Bridgetown to Buenos Aires
Operator: Azamara
Ship: Azamara Journey
Departure: 25 January 2027
Visits: Barbados, Trinidad and Tobago, French Guiana, Brazil, Uruguay, Argentina
Azamara Always Included
Exclusive Savings
Inside
$8,215
Oceanview
$8,734
Balcony
$11,174
Suite
$15,594
From (Per Person)
A$8,215
Per Person
View Trip
14 Day Barbados, French Guiana & Brazil Cruise: Bridgetown, Ile Royale & Rio De Janeiro with Azamara Cruises
Cruise
 (5)

14 Days (13 Nights) Bridgetown to Rio de Janeiro
Operator: Azamara
Ship: Azamara Journey
Departure: 25 January 2027
Visits: Barbados, Trinidad and Tobago, French Guiana, Brazil
Azamara Always Included
Exclusive Savings
Inside
$4,464
Oceanview
$5,023
Balcony
$6,336
Suite
$9,129
From (Per Person)
A$4,464
Per Person
View Trip
37 Day Caribbean To Cape Horn with Oceania Cruises
Cruise
 (1)

37 Days (36 Nights) Miami to Buenos Aires
Operator: Oceania
Ship: Oceania Insignia
Departure: 19 December 2026
Visits: USA, Curacao, Aruba, Colombia +7 more, Panama, Ecuador, Peru, Chile, Argentina, Falkland Islands, Uruguay
Your World Inclusions
Exclusive Savings
Inside
$16,048
Oceanview
$16,737
From (Per Person)
A$16,048
Save 2,332
Per Person
View Trip
59 Day Valparaiso To Miami Grand Voyage with Azamara Cruises
Cruise
 (6)

59 Days (58 Nights) Valparaiso to Miami
Operator: Azamara
Ship: Azamara Quest
Departure: 24 January 2028
Visits: Chile, Argentina, Antarctica, Falkland Islands +12 more, Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados, Grenada, Saint Lucia, Martinique, Dominica, Saint Martin, Virgin Islands, USA
Azamara Always Included
Exclusive Savings
Inside
-
Oceanview
$34,033
Balcony
$41,341
Suite
$69,309
From (Per Person)
A$35,818
Save 601
Per Person
View Trip
27 Day Brazil Intensive Cruise: Sao Paulo, Rio De Janiero & Salvador with Azamara Cruises
Cruise
 (6)

27 Days (26 Nights) Buenos Aires to Bridgetown
Operator: Azamara
Ship: Azamara Quest
Departure: 16 February 2028
Visits: Argentina, Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Exclusive Savings
Inside
$12,448
Oceanview
$14,161
Balcony
$17,122
Suite
$24,905
From (Per Person)
A$13,100
Save 199
Per Person
View Trip
20 Day Panama, Peru & Chile Cruise: Panama Canal, Lima & Coquimbo with Azamara Cruises
Cruise
 (6)

20 Days (19 Nights) Miami to Valparaiso
Operator: Azamara
Ship: Azamara Quest
Departure: 05 January 2028
Visits: USA, Mexico, Belize, Honduras +5 more, Costa Rica, Panama, Ecuador, Peru, Chile
Azamara Always Included
Exclusive Savings
Inside
$11,523
Oceanview
$13,040
Balcony
$15,843
Suite
$23,430
From (Per Person)
A$11,523
Save 796
Per Person
View Trip
13 Day Brazil Intensive Cruise: Sao Paulo, Poto Belo & Rio De Janeiro with Azamara Cruises
Cruise
 (6)

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Operator: Azamara
Ship: Azamara Quest
Departure: 16 February 2028
Visits: Argentina, Uruguay, Brazil
Azamara Always Included
Exclusive Savings
Inside
$6,011
Oceanview
$7,091
Balcony
$8,515
Suite
$12,286
From (Per Person)
A$6,011
Save 408
Per Person
View Trip
13 Day Bossa Nova Reverie with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Operator: Oceania
Ship: Oceania Insignia
Departure: 07 March 2027
Visits: Argentina, Uruguay, Brazil
Your World Inclusions
Exclusive Savings
Oceanview
$11,768
Suite
$13,020
From (Per Person)
A$11,768
Save 2,302
Per Person
View Trip
42 Day Miami To Auckland Grand Voyage with Azamara Cruises
Cruise
 (8)

42 Days (41 Nights) Miami to Auckland
Operator: Azamara
Ship: Azamara Onward
Departure: 05 January 2028
Visits: USA, Aruba, Curacao, Colombia +7 more, Panama, Ecuador, Peru, Chile, Pitcairn Islands, French Polynesia, New Zealand
Azamara Always Included
Exclusive Savings
Inside
$18,780
Oceanview
$19,255
Balcony
$24,887
Suite
$33,899
From (Per Person)
A$18,780
Save 1,299
Per Person
View Trip
29 Day Caribbean, Central America & Peru Cruise: Aruba, Miami & Panama Canal with Azamara Cruises
Cruise
 (6)

29 Days (28 Nights) Bridgetown to Valparaiso
Operator: Azamara
Ship: Azamara Quest
Departure: 27 December 2027
Visits: Barbados, Bonaire, Curacao, Aruba +11 more, Dominican Republic, Bahamas, USA, Mexico, Belize, Honduras, Costa Rica, Panama, Ecuador, Peru, Chile
Azamara Always Included
Exclusive Savings
Inside
$15,366
Oceanview
$18,103
Balcony
$22,069
Suite
$32,282
From (Per Person)
A$16,171
Save 268
Per Person
View Trip
15 Day Panama Canal To Machu Picchu with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Miami to Lima
Operator: Oceania
Ship: Oceania Sirena
Departure: 05 January 2028
Visits: USA, Cayman Islands, Jamaica, Colombia, Panama, Ecuador, Peru
Your World Inclusions
Exclusive Savings
Inside
$6,961
Oceanview
$7,659
Balcony
$9,589
Suite
$12,616
From (Per Person)
A$6,961
Save 2,139
Per Person
View Trip
66 Day South American Adventure with Oceania Cruises
Cruise
 (1)

66 Days (65 Nights) Miami to Miami
Operator: Oceania
Ship: Oceania Sirena
Departure: 05 January 2028
Visits: USA, Cayman Islands, Jamaica, Colombia +12 more, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, Barbados, Guadeloupe, Virgin Islands
Your World Inclusions
Exclusive Savings
Inside
$31,603
Oceanview
$32,845
Balcony
$43,389
Suite
-
From (Per Person)
A$31,603
Save 2,677
Per Person
View Trip
11 Day A Journey Through Amazonian Mesmerising Wonders to the Caribbean Sunlit Landscapes with Explora Journeys
Cruise
 (1)

11 Days (10 Nights) Manaus to San Juan
Operator: Explora Journeys
Ship: Explora II
Departure: 17 February 2028
Visits: Brazil, Trinidad and Tobago, Saint Lucia, Dominica, Saint Martin, Puerto Rico
Exclusive Savings
Suite
$9,673
From (Per Person)
A$9,673
Save 197
Per Person
View Trip
41 Day Amazon & Tropical Isles with Oceania Cruises
Cruise
 (1)

41 Days (40 Nights) Lisbon to Miami
Operator: Oceania
Ship: Oceania Insignia
Departure: 09 November 2026
Visits: Portugal, Spain, Puerto Rico, Dominican Republic +10 more, USA, Virgin Islands, Antigua and Barbuda, Saint Lucia, Trinidad and Tobago, Brazil, Barbados, Dominica, Saint Martin, Bahamas
Your World Inclusions
Exclusive Savings
Oceanview
$17,614
Balcony
$23,958
From (Per Person)
A$17,614
Save 2,386
Per Person
View Trip
11 Day Brazil Intensive Cruise: Rio De Janeiro, Paraty & Sao Paolo with Azamara Cruises
Cruise
 (5)

11 Days (10 Nights) Rio de Janeiro to Buenos Aires
Operator: Azamara
Ship: Azamara Journey
Departure: 07 February 2027
Visits: Brazil, Uruguay, Argentina
Azamara Always Included
Exclusive Savings
Inside
$3,506
Oceanview
$3,898
Balcony
$4,800
Suite
$6,740
From (Per Person)
A$3,506
Per Person
View Trip
20 Day Southern America & Panama Canal Cruise: Lima, Panama City & Cozumel with Azamara Cruises
Cruise
 (5)

20 Days (19 Nights) Santiago to Miami
Operator: Azamara
Ship: Azamara Journey
Departure: 10 March 2027
Visits: Chile, Peru, Panama, Costa Rica, Colombia, Mexico, USA
Azamara Always Included
Exclusive Savings
Inside
$6,289
Oceanview
$6,896
Balcony
$7,700
Suite
$12,247
From (Per Person)
A$6,289
Per Person
View Trip
15 Day Chilean Heritage & Fjords with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Lima to Punta Arenas
Operator: Oceania
Ship: Oceania Sirena
Departure: 19 January 2028
Visits: Peru, Chile
Your World Inclusions
Exclusive Savings
Inside
$6,669
Oceanview
$7,086
Balcony
$9,017
Suite
$12,877
From (Per Person)
A$6,669
Save 2,151
Per Person
View Trip
22 Day Amazonian Exploration with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Rio de Janeiro to Miami
Operator: Oceania
Ship: Oceania Sirena
Departure: 18 February 2028
Visits: Brazil, Barbados, Guadeloupe, Virgin Islands, USA
Your World Inclusions
Exclusive Savings
Inside
$10,062
Oceanview
$11,032
Balcony
$15,125
Suite
$27,793
From (Per Person)
A$10,062
Save 2,208
Per Person
View Trip
11 Day Panama, Ecuadaor & Peru Cruise: Panama City, Manta & Lima (Callao) with Azamara Cruises
Cruise
 (6)

11 Days (10 Nights) Panama City to Valparaiso
Operator: Azamara
Ship: Azamara Quest
Departure: 14 January 2028
Visits: Panama, Ecuador, Peru, Chile
Azamara Always Included
Exclusive Savings
Inside
$5,979
Oceanview
$7,012
Balcony
$8,614
Suite
$12,645
From (Per Person)
A$5,979
Save 420
Per Person
View Trip
7 Day Valparaiso to Callao (Lima) with Crystal Cruises
Cruise

7 Days (6 Nights) Valparaiso to Lima
Operator: Crystal
Ship: Crystal Serenity
Departure: 29 November 2027
Visits: Chile, Peru
Exclusive Savings
Oceanview
$5,277
Balcony
$6,252
Suite
$6,155
From (Per Person)
A$5,277
Save 123
Per Person
View Trip
13 Day Fort Lauderdale to Manaus with Crystal Cruises
Cruise

13 Days (12 Nights) Fort Lauderdale to Manaus
Operator: Crystal
Ship: Crystal Serenity
Departure: 18 January 2028
Visits: USA, Virgin Islands, Guadeloupe, Saint Lucia, Trinidad and Tobago, Brazil
Exclusive Savings
Oceanview
$10,945
Balcony
$12,895
Suite
$13,772
From (Per Person)
A$10,945
Save 255
Per Person
View Trip
26 Day Peru, Amazon & the Chilean Fjords Expedition - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

26 Days Lima to Buenos Aires
Operator: Scenic
Ship: Scenic Eclipse I
Departure: 22 October 2026
Trip Styles: Coach, Cruise, Wildlife, Scenic
Visits: Peru, Chile, Argentina
Exclusive Savings
Balcony
$40,865
Suite
-
From (Per Person)
A$40,865
Save 7,225
Per Person
View Trip
13 Day A Journey Of Amazon Exploration & Cultural Discovery with Explora Journeys
Cruise

13 Days (12 Nights) San Juan to Manaus
Operator: Explora Journeys
Ship: Explora I
Departure: 05 February 2027
Visits: Puerto Rico, Saint Barthelemy, Martinique, Barbados, Trinidad and Tobago, Brazil
Exclusive Savings
Suite
$12,833
From (Per Person)
A$12,833
Save 262
Per Person
View Trip
25 Day Ultimate Voyage: South America & Antarctica with Scenic
New ReleaseCruise

25 Days (24 Nights) Buenos Aires to Santiago
Operator: Scenic
Ship: Scenic Eclipse I
Departure: 01 March 2029
Visits: Argentina, Antarctica, Chile
Exclusive Savings
Balcony
$46,785
Suite
$64,229
From (Per Person)
A$46,785
Save 10,835
Per Person
View Trip
14 Day Ancient Kingdoms and Natural Treasures: Chile to Panama with Scenic
New ReleaseCruise

14 Days (13 Nights) Santiago to Panama City
Operator: Scenic
Ship: Scenic Eclipse II
Departure: 21 March 2027
Visits: Chile, Peru, Ecuador, Colombia, Panama
Exclusive Savings
Balcony
$12,533
Suite
$17,712
From (Per Person)
A$12,533
Save 4,212
Per Person
View Trip
11 Day From Panama’s Wild Beauty to Peruvian Shores with Ponant
Cruise

11 Days (10 Nights) Colon to Lima
Operator: Ponant
Ship: L'Austral
Departure: 20 October 2026
Visits: Panama, Peru
Exclusive Savings
Oceanview
$8,452
Balcony
$9,101
Suite
$16,939
From (Per Person)
A$8,452
Save 218
Per Person
View Trip
12 Day Rhythms of the Brazilian Coastline with Scenic
New ReleaseCruise

12 Days (11 Nights) Rio de Janeiro to Buenos Aires
Operator: Scenic
Ship: Scenic Eclipse II
Departure: 03 November 2027
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Balcony
$12,831
Suite
$17,138
From (Per Person)
A$12,831
Save 4,214
Per Person
View Trip
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