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South America Luxury Cruises

Explore the best luxury cruises around South America. Choose from 149 unique cruise itineraries with 162 past traveller reviews from 10 leading cruise lines. January is the most popular month to join a luxury cruise around South America with 267 departures starting between August 2026 and March 2029.
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146 Days
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149 Cruises (267 Cruise Departures)
113 Day Cape To Cape World Cruise: Miami To Lisbon with Seabourn
Cruise
 (1)

113 Days (112 Nights) Miami to Lisbon
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visit: USA, Panama, Ecuador, Peru (+18 more), Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Saint Helena, South Africa, Mozambique, Namibia, Angola, Sao Tome and Principe, Benin, Ghana, Senegal, Cape Verde, Spain, Morocco, Portugal
Exclusive Savings
Inside
-
Oceanview
$100,089
Balcony
$123,707
Suite
$288,632
From
A$100,089
Save 1,810
Per Person
View Trip
21 Day Bridgetown to Rio De Janeiro with Silversea
Cruise
 (1)

21 Days (20 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Silversea
Ship: Silver Nova
Departure: 18 January 2027
Visit: Barbados, Brazil
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$39,788
From
A$39,788
Save 812
Per Person
View Trip
22 Day Southern Fjords & Glaciers with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Valparaiso to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 14 February 2027
Visit: Chile, Argentina, Antarctica, Falkland Islands
Your World Inclusions
Exclusive Savings
Inside
$9,058
Oceanview
$9,524
Balcony
$13,442
Suite
$18,176
From
A$9,058
Save 2,202
Per Person
View Trip
35 Day South America Cruise: Miami, Rio De Janeiro & Buenos Aires with Azamara Cruises
Cruise
 (4)

35 Days (34 Nights) Miami to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 14 January 2027
Visit: USA, Virgin Islands, Saint Martin, Saint Kitts and Nevis (+10 more), Antigua and Barbuda, Martinique, Saint Vincent, Grenada, Barbados, Trinidad and Tobago, French Guiana, Brazil, Uruguay, Argentina
Azamara Always Included
Exclusive Savings
Inside
$16,910
Oceanview
$17,057
Balcony
$20,830
Suite
$32,669
From
A$16,910
Save 259
Per Person
View Trip
22 Day Amazonian Spirit with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Rio de Janeiro to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 19 March 2027
Visit: Brazil, Barbados, Antigua and Barbuda, Virgin Islands, USA
Your World Inclusions
Exclusive Savings
Inside
$8,649
Oceanview
$8,921
Balcony
$12,665
Suite
$17,224
From
A$8,649
Save 2,171
Per Person
View Trip
146 Day World Cruise: Australia & South Pacific Panorama with Seabourn
Cruise
 (1)

146 Days (145 Nights) Miami to Miami
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 January 2027
Visit: USA, Panama, Ecuador, Peru (+15 more), Chile, French Polynesia, Cook Islands, Tonga, New Zealand, Australia, Papua New Guinea, New Caledonia, Vanuatu, Fiji, Samoa, Mexico, Guatemala, Costa Rica, Colombia
Exclusive Savings
Inside
-
Oceanview
$118,698
Balcony
$143,551
Suite
$269,922
From
A$118,698
Save 2,221
Per Person
View Trip
64 Day World Cruise: Panama Canal, Polynesia & New Zealand with Seabourn
Cruise
 (1)

64 Days (63 Nights) Miami to Sydney
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 January 2027
Visit: USA, Panama, Ecuador, Peru (+6 more), Chile, French Polynesia, Cook Islands, Tonga, New Zealand, Australia
Exclusive Deal
Exclusive Savings
Inside
-
Oceanview
$44,868
Balcony
$54,962
Suite
$103,570
From
A$44,868
Save 830
Per Person
View Trip
22 Day Antarctica & Chilean Fjords Cruise: Buenos Aires, Ushuaia & Santiago with Azamara Cruises
Cruise
 (4)

22 Days (21 Nights) Buenos Aires to Santiago
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 17 February 2027
Visit: Argentina, Uruguay, Falkland Islands, Antarctica, Chile
Azamara Always Included
Exclusive Savings
Inside
$12,113
Oceanview
$12,848
Balcony
$14,318
Suite
$22,707
From
A$12,113
Save 196
Per Person
View Trip
78 Day Circle South America Grand Voyage with Azamara Cruises
Cruise
 (5)

78 Days (77 Nights) Miami to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+19 more), Costa Rica, Panama, Ecuador, Peru, Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados, Grenada, Saint Lucia, Martinique, Dominica, Saint Martin, Virgin Islands
Azamara Always Included
Exclusive Savings
Inside
$38,419
Oceanview
$41,555
Balcony
$50,286
Suite
$72,797
From
A$38,419
Save 600
Per Person
View Trip
34 Day Brazil Unbound with Oceania Cruises
Cruise
 (1)

34 Days (33 Nights) Buenos Aires to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 07 March 2027
Visit: Argentina, Uruguay, Brazil, Barbados, Antigua and Barbuda, Virgin Islands, USA
Your World Inclusions
Exclusive Savings
Inside
$13,676
Oceanview
$14,423
Balcony
-
Suite
-
From
A$13,676
Save 2,264
Per Person
View Trip
22 Day Patagonian Panorama with Oceania Cruises
Cruise
 (1)

22 Days (21 Nights) Lima to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 03 January 2027
Visit: Peru, Chile, Argentina, Falkland Islands, Uruguay
Your World Inclusions
Exclusive Savings
Inside
$9,316
Oceanview
$9,801
Balcony
$15,388
Suite
-
From
A$9,316
Save 2,204
Per Person
View Trip
20 Day Panama, Peru & Chile Cruise: Panama Canal, Lima & Coquimbo with Azamara Cruises
Cruise
 (5)

20 Days (19 Nights) Miami to Valparaiso
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 05 January 2028
Visit: USA, Mexico, Belize, Honduras (+5 more), Costa Rica, Panama, Ecuador, Peru, Chile
Azamara Always Included
Exclusive Savings
Inside
$8,608
Oceanview
$9,726
Balcony
$11,784
Suite
$16,831
From
A$8,608
Per Person
View Trip
50 Day Valparaiso To Bridgetown Grand Voyage with Azamara Cruises
Cruise
 (5)

50 Days (49 Nights) Valparaiso to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina, Antarctica, Falkland Islands (+5 more), Uruguay, Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Exclusive Savings
Inside
$24,424
Oceanview
$26,198
Balcony
$31,656
Suite
$54,118
From
A$24,424
Save 385
Per Person
View Trip
13 Day Bossa Nova Reverie with Oceania Cruises
Cruise
 (1)

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 07 March 2027
Visit: Argentina, Uruguay, Brazil
Your World Inclusions
Exclusive Savings
Inside
$5,327
Oceanview
$6,200
Balcony
$9,848
Suite
-
From
A$5,327
Save 2,103
Per Person
View Trip
15 Day Brazil Intensive Cruise: Salvador, Natal & Belem with Azamara Cruises
Cruise
 (5)

15 Days (14 Nights) Rio de Janeiro to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 28 February 2028
Visit: Brazil, French Guiana, Trinidad and Tobago, Barbados
Azamara Always Included
Exclusive Savings
Inside
$6,443
Oceanview
$7,570
Balcony
$9,109
Suite
$13,343
From
A$6,443
Per Person
View Trip
15 Day Chilean Heritage & Fjords with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Lima to Punta Arenas
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 19 January 2028
Visit: Peru, Chile
Your World Inclusions
Exclusive Savings
Inside
$6,136
Oceanview
$6,475
Balcony
$8,483
Suite
$12,897
From
A$6,136
Save 2,134
Per Person
View Trip
41 Day Buenos Aires To Miami Grand Voyage with Azamara Cruises
Cruise
 (4)

41 Days (40 Nights) Buenos Aires to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 17 February 2027
Visit: Argentina, Uruguay, Falkland Islands, Antarctica (+7 more), Chile, Peru, Panama, Costa Rica, Colombia, Mexico, USA
Azamara Always Included
Exclusive Savings
Inside
$23,280
Oceanview
$24,809
Balcony
$28,111
Suite
$42,772
From
A$23,280
Save 369
Per Person
View Trip
15 Day Panama Canal To Machu Picchu with Oceania Cruises
Cruise
 (1)

15 Days (14 Nights) Miami to Lima
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 January 2028
Visit: USA, Cayman Islands, Jamaica, Colombia, Panama, Ecuador, Peru
Your World Inclusions
Exclusive Savings
Inside
$6,214
Oceanview
$6,825
Balcony
$8,804
Suite
$12,082
From
A$6,214
Save 2,116
Per Person
View Trip
75 Day Circle South America Grand Voyage with Azamara Cruises
Cruise
 (4)

75 Days (74 Nights) Miami to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 14 January 2027
Visit: USA, Virgin Islands, Saint Martin, Saint Kitts and Nevis (+18 more), Antigua and Barbuda, Martinique, Saint Vincent, Grenada, Barbados, Trinidad and Tobago, French Guiana, Brazil, Uruguay, Argentina, Falkland Islands, Antarctica, Chile, Peru, Panama, Costa Rica, Colombia, Mexico
Azamara Always Included
Exclusive Savings
Inside
$40,492
Oceanview
$43,491
Balcony
$53,771
Suite
$77,125
From
A$40,492
Save 637
Per Person
View Trip
55 Day Epic Antarctic & Amazon with Oceania Cruises
Cruise
 (1)

55 Days (54 Nights) Valparaiso to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 14 February 2027
Visit: Chile, Argentina, Antarctica, Falkland Islands (+6 more), Uruguay, Brazil, Barbados, Antigua and Barbuda, Virgin Islands, USA
Your World Inclusions
Exclusive Savings
Inside
$22,521
Oceanview
$23,539
Balcony
-
Suite
-
From
A$22,521
Save 2,459
Per Person
View Trip
34 Day Captain Drake's Crossroads with Oceania Cruises
Cruise
 (1)

34 Days (33 Nights) Valparaiso to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 14 February 2027
Visit: Chile, Argentina, Antarctica, Falkland Islands, Uruguay, Brazil
Your World Inclusions
Exclusive Savings
Inside
$14,182
Oceanview
$14,987
Balcony
-
Suite
-
From
A$14,182
Save 2,298
Per Person
View Trip
41 Day Amazon & Tropical Isles with Oceania Cruises
Cruise
 (1)

41 Days (40 Nights) Lisbon to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 09 November 2026
Visit: Portugal, Spain, Puerto Rico, Bahamas (+9 more), USA, Virgin Islands, Antigua and Barbuda, Saint Lucia, Trinidad and Tobago, Brazil, Barbados, Dominica, Saint Martin
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
$15,945
Balcony
$22,425
Suite
$55,230
From
A$15,945
Save 2,335
Per Person
View Trip
42 Day Miami To Auckland Grand Voyage with Azamara Cruises
Cruise
 (8)

42 Days (41 Nights) Miami to Auckland
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 05 January 2028
Visit: USA, Aruba, Curacao, Colombia (+7 more), Panama, Ecuador, Peru, Chile, Pitcairn Islands, French Polynesia, New Zealand
Azamara Always Included
Exclusive Savings
Inside
$17,716
Oceanview
$19,117
Balcony
$21,998
Suite
$33,641
From
A$17,716
Save 273
Per Person
View Trip
13 Day Brazil Intensive Cruise: Sao Paulo, Poto Belo & Rio De Janeiro with Azamara Cruises
Cruise
 (5)

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 16 February 2028
Visit: Argentina, Uruguay, Brazil
Azamara Always Included
Exclusive Savings
Inside
$5,826
Oceanview
$6,864
Balcony
$8,217
Suite
$11,833
From
A$5,826
Per Person
View Trip
58 Day Panama Canal, Chilean Fjords, Antarctica & Falklands with Seabourn
Cruise
 (1)

58 Days (57 Nights) Miami to Buenos Aires
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 07 January 2028
Visit: USA, Panama, Ecuador, Peru (+5 more), Chile, Argentina, Antarctica, Falkland Islands, Uruguay
Exclusive Deal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$57,689
Suite
-
From
A$57,689
Save 1,059
Per Person
View Trip
11 Day Chile Intensive Cruise: Puerto Montt, Castro & Punta Arenas with Azamara Cruises
Cruise
 (5)

11 Days (10 Nights) Valparaiso to Ushuaia
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 24 January 2028
Visit: Chile, Argentina
Azamara Always Included
Exclusive Savings
Inside
$4,469
Oceanview
$5,234
Balcony
$6,419
Suite
$9,820
From
A$4,469
Save 70
Per Person
View Trip
36 Day World Cruise: Panama Canal Crossing & Polynesia with Seabourn
Cruise
 (1)

36 Days (35 Nights) Miami to Tahiti
Cruise Line: Seabourn
Ship: Seabourn Quest
Departure: 05 January 2027
Visit: USA, Panama, Ecuador, Peru, Chile, Easter Island, French Polynesia
Exclusive Deal
Exclusive Savings
Inside
-
Oceanview
$23,860
Balcony
$27,878
Suite
$58,748
From
A$23,860
Save 438
Per Person
View Trip
19 Day Valparaiso to Miami with Silversea
Cruise
 (1)

19 Days (18 Nights) Valparaiso to Miami
Cruise Line: Silversea
Ship: Silver Nova
Departure: 05 March 2027
Visit: Chile, Peru, Ecuador, Panama, Mexico, USA
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,767
Suite
$31,458
From
A$17,767
Save 8,133
Per Person
View Trip
7 Day Ocean Voyage: Ushuaia - Buenos Aires with Ponant
Cruise
 (2)

7 Days (6 Nights) Ushuaia to Buenos Aires
Cruise Line: Ponant
Ship: Le Boreal
Departure: 12 March 2028
Visit: Argentina
Exclusive Savings
Inside
-
Oceanview
$2,341
Balcony
$2,516
Suite
$4,019
From
A$2,341
Save 59
Per Person
View Trip
11 Day Rio De Janeiro to Buenos Aires with Silversea
Cruise
 (1)

11 Days (10 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Silversea
Ship: Silver Nova
Departure: 07 February 2027
Visit: Brazil, Uruguay, Argentina
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$17,248
Suite
$28,322
From
A$17,248
Save 352
Per Person
View Trip
Results: 31-60 of 149

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