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South America Luxury Cruises

Explore the best luxury cruises around South America. Choose from 130 unique cruise itineraries from 8 leading cruise lines. January is the most popular month to join a luxury cruise around South America with 257 departures starting between June 2024 and March 2026.
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130 Cruises (257 Cruise Departures)
8 Day San Cristóbal, Galapagos to San Cristóbal, Galapagos with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departure: 05 April 2025
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$21,087
SUITE
$33,165
From 21,087
View Trip
15 Day Season Of Samba with Regent Seven Seas
Cruise

15 Days (14 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 03 December 2025
Countries Visited: Barbados, Saint Vincent, Trinidad and Tobago, French Guiana (+1 more), Brazil
Land Package Credit
INSIDE
-
OCEANVIEW
-
BALCONY
$13,761
SUITE
$15,533
Save 8,269
From 13,761
View Trip
12 Day Wonders of the Galápagos & Machu Picchu: Northern Islands Route with Abercrombie & Kent
New ReleaseTour + Cruise

12 Days Guayaquil to Lima
Operated By: Abercrombie & Kent
Departures: Feb 2025 to Nov 2025
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos, Peru
From 26,465
View Trip
19 Day Cape Horn Encounter with Oceania Cruises
Cruise

19 Days (18 Nights) San Antonio to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 06 March 2025
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Cabin Upgrade Offer
INSIDE
$8,111
OCEANVIEW
-
BALCONY
$9,794
SUITE
$12,160
From 8,111
View Trip
11 Day Brazilian Brilliance with Oceania Cruises
Cruise

11 Days (10 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 March 2026
Countries Visited: Argentina, Uruguay, Brazil
Exclusive Deal
INSIDE
$5,124
OCEANVIEW
$5,807
BALCONY
$6,421
SUITE
$8,955
Save 2,036
From 5,124
View Trip
26 Day Carnival Rio & Amazon Voyage with Azamara Cruises
Cruise

26 Days (25 Nights) Buenos Aires to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 25 February 2025
Countries Visited: Argentina, Uruguay, Brazil, French Guiana (+1 more), Barbados
INSIDE
$9,243
OCEANVIEW
$11,052
BALCONY
-
SUITE
-
From 9,243
View Trip
29 Day Wild Guianas, Amazon & Coast Of Brazil with Seabourn
Cruise

29 Days (28 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Seabourn
Ship: Venture
Departure: 07 October 2024
Countries Visited: Barbados, Trinidad and Tobago, French Guiana, Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$28,052
SUITE
-
From 28,052
View Trip
10 Day Heart Of The Amazon with Seabourn
Cruise

10 Days (9 Nights) Manaus to Manaus
Cruise Line: Seabourn
Ship: Venture
Departure: 21 October 2025
Countries Visited: Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$15,197
SUITE
$29,334
From 15,197
View Trip
8 Day San Cristóbal, Galapagos to San Cristóbal, Galapagos with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Jul 2024 to Mar 2026
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$17,226
SUITE
$25,245
From 17,226
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) San Cristobal Island to San Cristobal Island
Cruise Line: Silversea
Ship: Silver Origin
Departure: 21 March 2026
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$20,592
SUITE
$37,323
From 20,592
View Trip
12 Day Valparaiso to Puerto Williams with Silversea
Cruise

12 Days (11 Nights) Valparaiso to Santiago
Cruise Line: Silversea
Ship: Silver Endeavour
Departure: 12 October 2025
Countries Visited: Chile, Argentina
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$20,394
From 20,394
View Trip
11 Day Brazilian Rhythms with Oceania Cruises
Cruise

11 Days (10 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 24 January 2026
Countries Visited: Brazil, Uruguay, Argentina
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$6,420
SUITE
$8,955
Save 2,050
From 6,420
View Trip
23 Day Beauty At The End Of The World with Regent Seven Seas
Cruise

23 Days (22 Nights) Rio de Janeiro to Santiago
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 25 January 2025
Countries Visited: Brazil, Uruguay, Argentina, Falkland Islands (+1 more), Chile
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$15,501
SUITE
$16,980
Save 17,549
From 15,501
View Trip
13 Day Valparaiso to Puerto Williams with Silversea
Cruise

13 Days (12 Nights) Valparaiso to Puerto Williams
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 07 November 2024
Countries Visited: Argentina, Chile
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$10,593
BALCONY
$14,949
SUITE
$19,800
From 10,593
View Trip
17 Day Lima to Fort Lauderdale with Silversea
Cruise

17 Days (16 Nights) Lima to Fort Lauderdale
Cruise Line: Silversea
Ship: Silver Ray
Departure: 04 January 2025
Countries Visited: Aruba, Colombia, Ecuador, Panama (+2 more), Peru, USA
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$12,870
From 12,870
View Trip
15 Day Wild Guianas To The Amazon Basin with Seabourn
Cruise

15 Days (14 Nights) Bridgetown to Manaus
Cruise Line: Seabourn
Ship: Venture
Departure: 07 October 2024
Countries Visited: Barbados, Trinidad and Tobago, French Guiana, Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$18,357
SUITE
$34,851
From 18,357
View Trip
13 Day Valparaiso to Buenos Aires with Silversea
Cruise

13 Days (12 Nights) Valparaiso to Buenos Aires
Cruise Line: Silversea
Ship: Silver Ray
Departure: 09 February 2025
Countries Visited: Argentina, Chile
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$13,711
From 13,711
View Trip
15 Day Amazon Delta & Coast Of Brazil with Seabourn
Cruise

15 Days (14 Nights) Manaus to Rio de Janeiro
Cruise Line: Seabourn
Ship: Venture
Departure: 21 October 2024
Countries Visited: Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$12,808
SUITE
$18,951
From 12,808
View Trip
17 Day Edge Of The World Expedition with Regent Seven Seas
Cruise

17 Days (16 Nights) Santiago to Buenos Aires
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 01 February 2026
Countries Visited: Chile, Argentina, Uruguay
Land Package Credit
INSIDE
-
OCEANVIEW
-
BALCONY
$18,481
SUITE
$20,115
Save 8,169
From 18,481
View Trip
12 Day Wonders of the Galápagos & Machu Picchu with Abercrombie & Kent
New ReleaseTour + Cruise

12 Days Guayaquil to Lima
Operated By: Abercrombie & Kent
Departures: Jul 2024 to Nov 2024
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos, Peru
Exclusive Solo Offer
From 26,490
View Trip
33 Day Fort Lauderdale to Buenos Aires with Silversea
Cruise

33 Days (32 Nights) Fort Lauderdale to Buenos Aires
Cruise Line: Silversea
Ship: Silver Ray
Departure: 20 January 2025
Countries Visited: USA, Mexico, Panama, Ecuador (+3 more), Peru, Chile, Argentina
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$26,532
From 26,532
View Trip
8 Day San Cristóbal, Galapagos to San Cristóbal, Galapagos with Silversea
Cruise

8 Days (7 Nights) Quito to Quito
Cruise Line: Silversea
Ship: Silver Origin
Departures: Jun 2024 to Aug 2025
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$17,226
SUITE
$22,968
Save 706
From 17,226
View Trip
10 Day Heart Of The Amazon with Seabourn
Cruise

10 Days (9 Nights) Manaus to Manaus
Cruise Line: Seabourn
Ship: Venture
Departure: 12 October 2025
Countries Visited: Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$15,197
SUITE
$29,334
From 15,197
View Trip
15 Day Peru & the Galapagos Islands with Tauck
Tour + Cruise

15 Days Lima to Guayaquil
Operated By: Tauck
Departures: Sep 2024 to Oct 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
From 19,700
View Trip
13 Day Ushuaia to Valparaiso with Silversea
Cruise

13 Days (12 Nights) Ushuaia to Valparaiso
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 19 March 2025
Countries Visited: Argentina, Chile
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$12,870
SUITE
$19,107
From 12,870
View Trip
25 Day Palms To Penguins with Oceania Cruises
Cruise

25 Days (24 Nights) Rio de Janeiro to San Antonio
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 22 January 2026
Countries Visited: Brazil, Uruguay, Argentina, Falkland Islands (+1 more), Chile
Exclusive Deal
INSIDE
$11,801
OCEANVIEW
$13,405
BALCONY
$15,009
SUITE
$21,493
Save 2,089
From 11,801
View Trip
15 Day The Best of Chilean Fjords with Ponant
Cruise

15 Days (14 Nights) Valparaiso to Buenos Aires
Cruise Line: Ponant
Ships: Le Boreal, Le Lyrial
Departures: Oct 2024 to Nov 2025
Countries Visited: Chile, Argentina
Exclusive Savings
INSIDE
-
OCEANVIEW
$11,206
BALCONY
$12,000
SUITE
$19,438
Save 275
From 11,206
View Trip
12 Day Wonders of the Galápagos & Machu Picchu: Eastern Islands Route with Abercrombie & Kent
New ReleaseTour + Cruise

12 Days Guayaquil to Lima
Operated By: Abercrombie & Kent
Departures: Apr 2025 to Oct 2025
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos, Peru
From 27,245
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departure: 01 November 2025
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$17,919
SUITE
$26,730
From 17,919
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) San Cristobal Island to San Cristobal Island
Cruise Line: Silversea
Ship: Silver Origin
Departures: Jul 2024 to Mar 2025
Countries Visited: Ecuador, Galapagos
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$13,414
SUITE
$22,374
Save 216
From 13,414
View Trip
Results: 31-60 of 130

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