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South America Luxury Cruises

Explore the best luxury cruises around South America. Choose from 130 unique cruise itineraries from 8 leading cruise lines. January is the most popular month to join a luxury cruise around South America with 257 departures starting between June 2024 and March 2026.
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130 Cruises (257 Cruise Departures)
9 Day Lima to Valparaiso with Silversea
Cruise

9 Days (8 Nights) Lima to Valparaiso
Cruise Line: Silversea
Ship: Silver Wind
Departure: 10 November 2024
Countries Visited: Peru, Chile
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
$7,326
BALCONY
$8,712
SUITE
-
From 7,326
View Trip
31 Day South America Connoisseur with Oceania Cruises
Cruise

31 Days (30 Nights) San Antonio to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 06 March 2025
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay (+1 more), Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$16,732
SUITE
$22,662
Save 2,128
From 16,732
View Trip
21 Day Rio De Janeiro to Bridgetown with Silversea
Cruise

21 Days (20 Nights) Rio de Janeiro to Bridgetown
Cruise Line: Silversea
Ship: Silver Ray
Departure: 03 March 2025
Countries Visited: Barbados, Brazil, French Guiana
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$21,978
From 21,978
View Trip
34 Day Hamburg To Rio De Janeiro with Cunard
Cruise

34 Days (33 Nights) Hamburg to Rio de Janeiro
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 04 January 2025
Countries Visited: Germany, Holland, Belgium, England (+5 more), Portugal, USA, Turks and Caicos Islands, Barbados, Brazil
INSIDE
$8,216
OCEANVIEW
$9,614
BALCONY
$12,584
SUITE
$28,721
From 8,216
View Trip
17 Day Canary Islands Crossing with Regent Seven Seas
Cruise

17 Days (16 Nights) Rio de Janeiro to Lisbon
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 13 March 2025
Countries Visited: Brazil, Cape Verde, Spain, Portugal
Non-Use Land Package Credit
INSIDE
-
OCEANVIEW
-
BALCONY
$10,831
SUITE
$12,316
Save 5,659
From 10,831
View Trip
25 Day Amazonian Mystique with Oceania Cruises
Cruise
 (1)

25 Days (24 Nights) Miami to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 09 November 2024
Countries Visited: USA, Antigua and Barbuda, Saint Lucia, Grenada (+7 more), Trinidad and Tobago, Brazil, Barbados, Dominica, Virgin Islands, Puerto Rico, Bahamas
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$16,077
SUITE
$21,264
Save 2,123
From 16,077
View Trip
19 Day Amazon Trailblazer with Oceania Cruises
Cruise
 (2)

19 Days (18 Nights) Bridgetown to Bridgetown
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 04 January 2025
Countries Visited: Barbados, Trinidad and Tobago, Brazil, French Guiana (+3 more), Grenada, Guadeloupe, Saint Lucia
Exclusive Deal
INSIDE
$9,186
OCEANVIEW
-
BALCONY
-
SUITE
-
Save 2,064
From 9,186
View Trip
26 Day Amazing Amazon To Antilles with Oceania Cruises
Cruise
 (2)

26 Days (25 Nights) Bridgetown to Bridgetown
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 04 January 2025
Countries Visited: Barbados, Trinidad and Tobago, Brazil, French Guiana (+7 more), Grenada, Guadeloupe, Saint Lucia, Martinique, Saint Barthelemy, Dominica, Saint Vincent
Exclusive Deal
INSIDE
$12,106
OCEANVIEW
-
BALCONY
-
SUITE
-
Save 2,084
From 12,106
View Trip
17 Day Colombia, Ecuador & Peru Voyage with Azamara Cruises
Cruise

17 Days (16 Nights) Miami to Lima
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 07 January 2025
Countries Visited: USA, Aruba, Bonaire, Curacao (+3 more), Colombia, Ecuador, Peru
INSIDE
$6,626
OCEANVIEW
$7,826
BALCONY
$9,665
SUITE
$15,182
From 6,626
View Trip
25 Day The Colors Of Carnival with Regent Seven Seas
Cruise

25 Days (24 Nights) Buenos Aires to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 17 February 2026
Countries Visited: Argentina, Uruguay, Brazil, French Guiana (+4 more), Saint Lucia, Dominica, Sint Maarten, USA
Land Package Credit
INSIDE
-
OCEANVIEW
-
BALCONY
$20,998
SUITE
$23,513
Save 9,692
From 20,998
View Trip
26 Day Call Of The Amazon with Oceania Cruises
Cruise

26 Days (25 Nights) Miami to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 12 November 2025
Countries Visited: USA, Antigua and Barbuda, Saint Lucia, Grenada (+6 more), Trinidad and Tobago, Brazil, Barbados, Dominica, Sint Maarten, Puerto Rico
Exclusive Deal
INSIDE
$10,748
OCEANVIEW
$11,511
BALCONY
$16,094
SUITE
$22,589
Save 2,072
From 10,748
View Trip
18 Day Escape & Delight In Brazil with Regent Seven Seas
Cruise

18 Days (17 Nights) Miami to Rio de Janeiro
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 08 January 2025
Countries Visited: USA, Dominica, Barbados, French Guiana (+1 more), Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,342
SUITE
$11,673
Save 13,348
From 10,342
View Trip
32 Day Island & Amazon Immersion with Oceania Cruises
Cruise

32 Days (31 Nights) Miami to Bridgetown
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 15 January 2026
Countries Visited: USA, Aruba, Curacao, Trinidad and Tobago (+8 more), Grenada, Saint Lucia, Saint Vincent, Dominica, Martinique, Barbados, Brazil, French Guiana
Exclusive Deal
INSIDE
$13,073
OCEANVIEW
$14,300
BALCONY
$19,943
SUITE
$28,022
Save 2,087
From 13,073
View Trip
22 Day Heart Of The Amazon with Oceania Cruises
Cruise

22 Days (21 Nights) Rio de Janeiro to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 17 March 2026
Countries Visited: Brazil, Saint Lucia, Saint Kitts and Nevis, USA
Exclusive Deal
INSIDE
$9,433
OCEANVIEW
$10,968
BALCONY
$12,413
SUITE
$18,106
Save 2,067
From 9,433
View Trip
42 Day Caribbean & Amazon Icons with Oceania Cruises
Cruise

42 Days (41 Nights) Boston to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 27 October 2025
Countries Visited: USA, Bermuda, Saint Barthelemy, Antigua and Barbuda (+10 more), Saint Lucia, Barbados, Grenada, Bonaire, Aruba, Trinidad and Tobago, Brazil, Dominica, Sint Maarten, Puerto Rico
Exclusive Deal
INSIDE
$15,016
OCEANVIEW
$15,778
BALCONY
$22,342
SUITE
$31,272
Save 2,094
From 15,016
View Trip
30 Day Rio De Janeiro to Fort Lauderdale with Silversea
Cruise

30 Days (29 Nights) Rio de Janeiro to Fort Lauderdale
Cruise Line: Silversea
Ship: Silver Ray
Departure: 03 March 2025
Countries Visited: Brazil, French Guiana, Barbados, Saint Vincent (+5 more), Saint Lucia, Antigua and Barbuda, Virgin Islands, Puerto Rico, USA
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$22,869
From 22,869
View Trip
20 Day Amazon To Caribbean Gems with Oceania Cruises
Cruise

20 Days (19 Nights) Bridgetown to Bridgetown
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 27 January 2026
Countries Visited: Barbados, Brazil, French Guiana, Trinidad and Tobago (+3 more), Grenada, Saint Vincent, Saint Lucia
Exclusive Deal
INSIDE
$8,405
OCEANVIEW
$9,246
BALCONY
$13,296
SUITE
$19,275
Save 2,055
From 8,405
View Trip
19 Day Vibrant Voyage To Rio with Oceania Cruises
Cruise

19 Days (18 Nights) Miami to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 06 January 2026
Countries Visited: USA, Saint Barthelemy, Dominica, Barbados (+2 more), French Guiana, Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$9,860
SUITE
$15,830
Save 2,080
From 9,860
View Trip
32 Day Mythical Secrets Of Brazil with Oceania Cruises
Cruise

32 Days (31 Nights) Buenos Aires to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 07 March 2026
Countries Visited: Argentina, Uruguay, Brazil, Saint Lucia (+2 more), Saint Kitts and Nevis, USA
Exclusive Deal
INSIDE
$13,546
OCEANVIEW
$15,526
BALCONY
$17,516
SUITE
$25,436
Save 2,094
From 13,546
View Trip
18 Day San Antonio To Fort Lauderdale with Cunard
Cruise

18 Days (17 Nights) Santiago to Fort Lauderdale
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 25 February 2025
Countries Visited: Chile, Peru, Ecuador, Panama (+3 more), Aruba, Bahamas, USA
INSIDE
$4,658
OCEANVIEW
$5,450
BALCONY
$7,232
SUITE
$16,340
From 4,658
View Trip
26 Day Emerald Reefs & Amazon Adventure with Regent Seven Seas
Cruise

26 Days (25 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 24 February 2025
Countries Visited: USA, Saint Barthelemy, Trinidad and Tobago, Grenada (+6 more), Brazil, Barbados, Dominica, Sint Maarten, Puerto Rico, Bahamas
Exclusive Deal
INSIDE
-
OCEANVIEW
$17,473
BALCONY
-
SUITE
$31,650
Save 4,547
From 17,473
View Trip
25 Day Radiant Amazon with Regent Seven Seas
Cruise

25 Days (24 Nights) Miami to Miami
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 17 November 2024
Countries Visited: USA, Saint Barthelemy, Trinidad and Tobago, Grenada (+6 more), Brazil, Barbados, Dominica, Sint Maarten, Puerto Rico, Bahamas
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$13,528
SUITE
$14,781
Save 11,552
From 13,528
View Trip
23 Day Antilles To Amazon with Oceania Cruises
Cruise

23 Days (22 Nights) Miami to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 05 January 2025
Countries Visited: USA, Sint Maarten, Dominica, Barbados (+1 more), Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
$11,885
BALCONY
$14,944
SUITE
-
Save 2,085
From 11,885
View Trip
16 Day King George Island to Puerto Williams with Silversea
Cruise

16 Days (15 Nights) King George Island to Puerto Williams
Cruise Line: Silversea
Ship: Silver Endeavour
Departure: 06 January 2025
Countries Visited: Antarctica, South Georgia Island, Falkland Islands, Chile
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$49,698
From 49,698
View Trip
24 Day Southern Journey Voyage with Azamara Cruises
Cruise

24 Days (23 Nights) San Antonio to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 02 February 2025
Countries Visited: Chile, Argentina, Antarctica, Falkland Islands (+1 more), Uruguay
INSIDE
$8,702
OCEANVIEW
$10,579
BALCONY
$12,693
SUITE
-
From 8,702
View Trip
23 Day Puerto Williams to Valparaiso with Silversea
Cruise

23 Days (22 Nights) Santiago to Valparaiso
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 06 March 2026
Countries Visited: Chile, Argentina, Antarctica
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$26,433
BALCONY
$30,888
SUITE
$50,193
From 26,433
View Trip
23 Day Puerto Williams to Valparaiso with Silversea
Cruise

23 Days (22 Nights) Puerto Williams to Valparaiso
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 09 March 2025
Countries Visited: Argentina, Chile, Antarctica
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$28,809
BALCONY
$33,264
SUITE
$46,728
From 28,809
View Trip
19 Day Far & Wide: The Ultimate Odyssey with Oceania Cruises
Cruise

19 Days (18 Nights) Buenos Aires to San Antonio
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 16 February 2025
Countries Visited: Argentina, Falkland Islands, Antarctica, Chile
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$57,799
SUITE
$78,302
Save 2,501
From 57,799
View Trip
19 Day Puerto Williams to Puerto Williams with Silversea
Cruise

19 Days (18 Nights) Santiago to Santiago
Cruise Line: Silversea
Ship: Silver Endeavour
Departures: Oct 2024 to Feb 2026
Countries Visited: Chile, Falkland Islands, South Georgia Island, Antarctica
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$39,105
From 39,105
View Trip
22 Day Puerto Williams to Buenos Aires with Silversea
Cruise

22 Days (21 Nights) Puerto Williams to Buenos Aires
Cruise Line: Silversea
Ship: Silver Endeavour
Departure: 10 March 2025
Countries Visited: Argentina, Chile, Falkland Islands, Antarctica
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$33,462
From 33,462
View Trip
Results: 61-90 of 130

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