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Cruises from Spain to Italy

Are you looking for a cruise from Spain to Italy? April and August are the most popular months to cruise between Spain and Italy and there are 178 departures available from fourteen of the world's leading cruise lines.
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94 Cruises (178 Cruise Departures)
12 Day Europe - Classic Mediterranean with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Barcelona to Venice
Ship: Norwegian Epic
Departure: 17 August 2023
Countries Visited: Spain, France, Italy, Sicily (+3 more), Greece, Montenegro, Croatia
Inside
$2,410
Oceanview
-
Balcony
$3,850
Suite
$3,675
From 2,410
View Trip
8 Day Mediterranean with Princess
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Enchanted Princess
Departures: Jun 2023 to Aug 2023
Countries Visited: Spain, Gibraltar, France, Italy
Inside
$1,488
Oceanview
$1,882
Balcony
$1,696
Suite
$2,340
From 1,488
View Trip
8 Day Mediterranean with France & Italy with Princess
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departures: May 2024 to Sep 2025
Countries Visited: Spain, Gibraltar, France, Italy
Inside
$1,545
Oceanview
$1,921
Balcony
$2,060
Suite
$3,059
From 1,545
View Trip
13 Day Vita Est Bona with Regent Seven Seas
Cruise

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 24 August 2024
Countries Visited: Spain, France, Monaco, Italy (+1 more), Sardinia
Early Booking Savings
Inside
-
Oceanview
-
Balcony
$16,892
Suite
$19,961
From 16,892
View Trip
10 Day Italian Riviera & France Cruise with Celebrity Cruises
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departures: Sep 2024 to Oct 2024
Countries Visited: Spain, France, Corsica, Italy (+2 more), Malta, Sicily
The Retreat Plus Bonus OffersSpring Into Summer Sale
Inside
$2,566
Oceanview
$2,838
Balcony
$3,248
Suite
$8,711
From 2,566
View Trip
15 Day France, Italy And Adriatic with Cunard
Cruise

15 Days (14 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departures: Jun 2024 to Sep 2024
Countries Visited: Spain, Sardinia, Corsica, Sicily (+4 more), Italy, Greece, Montenegro, Croatia
Inside
$2,776
Oceanview
$3,221
Balcony
$3,568
Suite
$7,379
From 2,776
View Trip
11 Day Marvelous Mediterranean with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 15 May 2024
Countries Visited: Spain, France, Monaco, Italy (+1 more), Corsica
Early Booking Savings
Inside
$4,446
Oceanview
$4,882
Balcony
-
Suite
-
From 4,446
View Trip
12 Day Europe - Western Mediterranean - Barcelona with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Barcelona to Venice
Ships: Norwegian Breakaway, Norwegian Escape
Departures: May 2024 to Sep 2025
Countries Visited: Spain, France, Italy, Sicily (+3 more), Malta, Greece, Croatia
Inside
$3,538
Oceanview
$4,299
Balcony
$4,604
Suite
$4,909
From 3,538
View Trip
3 Day Mediterranean with MSC Cruises
Cruise

3 Days (2 Nights) Alicante to Genoa
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 13 April 2024
Countries Visited: Spain, Italy
Inside
$158
Oceanview
$237
Balcony
$306
Suite
$455
From 148
View Trip
24 Day Mediterranean Tapestry & Empires with Holland America
Cruise

24 Days (23 Nights) Barcelona to Venice
Cruise Line: Holland America
Ship: Oosterdam
Departure: 12 June 2024
Countries Visited: Spain, France, Italy, Sicily (+6 more), Malta, Tunisia, Greece, Turkey, Albania, Croatia
Have It All Early Booking Bonus Offer
Inside
$7,385
Oceanview
$8,177
Balcony
$9,514
Suite
$12,979
From 7,385
View Trip
8 Day Mediterranean Spring with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 06 May 2025
Countries Visited: Spain, France, Monaco, Italy
Early Booking Savings
Inside
$3,019
Oceanview
$3,236
Balcony
$4,741
Suite
$6,375
From 3,019
View Trip
13 Day Barcelona to Rome with Silversea
Cruise

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Moon
Departure: 17 October 2023
Countries Visited: Spain, France, Italy, Sardinia
Port-to-Port Only
Inside
-
Oceanview
$11,632
Balcony
$12,127
Suite
-
From 11,632
View Trip
11 Day Charismatic Mediterranean with Oceania Cruises
Cruise

11 Days (10 Nights) Barcelona to Venice
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 19 April 2024
Countries Visited: Spain, France, Monaco, Italy (+4 more), Sicily, Greece, Montenegro, Croatia
Early Booking Savings
Inside
-
Oceanview
-
Balcony
$6,792
Suite
$9,386
From 6,792
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Malaga to Genoa
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 12 April 2024
Countries Visited: Spain, Italy
Inside
-
Oceanview
$307
Balcony
-
Suite
-
From 208
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Barcelona to Genoa
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 17 November 2023
Countries Visited: Spain, Morocco, Portugal, France (+1 more), Italy
Limited Time Sale
Inside
$1,318
Oceanview
-
Balcony
$2,080
Suite
$2,981
From 1,318
View Trip
8 Day Mediterranean with France & Italy with Princess
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Majestic Princess
Departure: 04 March 2025
Countries Visited: Spain, Gibraltar, Corsica, Italy
Inside
$1,869
Oceanview
-
Balcony
$2,661
Suite
$3,373
From 1,869
View Trip
13 Day Epicurean Spotlight On Wine with Regent Seven Seas
Cruise

13 Days (12 Nights) Tarragona to Venice
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 08 October 2023
Countries Visited: Spain, France, Monaco, Italy (+3 more), Montenegro, Croatia, Slovenia
Early Booking Savings
Inside
-
Oceanview
-
Balcony
$16,920
Suite
$18,455
From 16,920
View Trip
3 Day Mediterranean with MSC Cruises
Cruise

3 Days (2 Nights) Barcelona to Genoa
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Seaview
Departures: Oct 2023 to Apr 2024
Countries Visited: Spain, France, Italy
Limited Time Sale
Inside
$222
Oceanview
$302
Balcony
$361
Suite
$569
From 212
View Trip
11 Day Barcelona to Rome with Silversea
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Moon
Departure: 16 August 2024
Countries Visited: France, Italy, Spain
Door-to-Door Economy Class Included
Inside
-
Oceanview
$11,781
Balcony
$13,365
Suite
$19,998
From 11,781
View Trip
8 Day Glory Of The Riviera with Regent Seven Seas
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 24 April 2024
Countries Visited: Spain, France, Monaco, Italy
Early Booking Savings
Inside
-
Oceanview
-
Balcony
$11,195
Suite
$12,521
From 11,195
View Trip
11 Day Inaugural Grand Mediterranean with Princess
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 08 February 2024
Countries Visited: Spain, Sicily, Greece, Turkey (+1 more), Italy
Inside
$1,918
Oceanview
$2,316
Balcony
$2,650
Suite
$3,448
From 1,918
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Royal Caribbean
Ship: Enchantment of the Seas
Departure: 25 September 2023
Countries Visited: Spain, France, Italy
Limited Time Sale
Inside
$1,161
Oceanview
$1,755
Balcony
$4,125
Suite
$4,071
From 1,161
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Malaga to Genoa
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 24 November 2023
Countries Visited: Spain, France, Italy
Limited Time Sale
Inside
$401
Oceanview
$500
Balcony
$609
Suite
$1,064
From 401
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Alicante to Genoa
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 05 November 2023
Countries Visited: Spain, Sardinia, Italy
Limited Time Sale
Inside
$332
Oceanview
-
Balcony
$658
Suite
$1,203
From 332
View Trip
13 Day Europe - France & Iberia with Norwegian Cruise Line
Cruise

13 Days (12 Nights) Bilbao to Rome
Ship: Norwegian Gem
Departure: 19 September 2023
Countries Visited: Spain, Portugal, Gibraltar, France (+1 more), Italy
Inside
$2,061
Oceanview
$2,594
Balcony
$3,585
Suite
$4,040
From 2,061
View Trip
21 Day Western Mediterranean & Adriatic Explorer with Princess
Cruise
 (1)

21 Days (20 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Island Princess
Departure: 05 August 2024
Countries Visited: Spain, Gibraltar, France, Italy (+5 more), Sicily, Malta, Greece, Montenegro, Croatia
Inside
$4,296
Oceanview
$4,557
Balcony
$6,227
Suite
$7,368
From 4,296
View Trip
9 Day Mediterranean with MSC Cruises
Cruise

9 Days (8 Nights) Barcelona to Genoa
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 07 April 2024
Countries Visited: Spain, Morocco, Italy
Inside
$870
Oceanview
$1,108
Balcony
-
Suite
$2,098
From 870
View Trip
13 Day Mediterranean Odyssey with Viking Cruises
Cruise

13 Days (12 Nights) Barcelona to Venice
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Saturn (+2 more), Viking Sea, Viking Star
Departures: Apr 2024 to Aug 2025
Countries Visited: Spain, France, Italy, Greece (+1 more), Croatia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,619
Suite
$12,735
Save 190
From 8,619
View Trip
11 Day Europe - Western Mediterranean with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Barcelona to Venice
Ship: Norwegian Escape
Departure: 11 August 2024
Countries Visited: Spain, France, Italy, Sicily (+3 more), Malta, Greece, Croatia
Inside
$3,356
Oceanview
$3,995
Balcony
$4,757
Suite
$4,909
From 3,356
View Trip
10 Day Italian Riviera & France with Celebrity Cruises
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Jul 2024 to Aug 2024
Countries Visited: Spain, Italy, France
The Retreat Plus Bonus OffersSpring Into Summer Sale
Inside
$2,061
Oceanview
$2,375
Balcony
$2,641
Suite
$7,204
From 2,061
View Trip
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