Cruises from Spain to Italy

Are you looking for a cruise from Spain to Italy? September is the most popular month to cruise between Spain and Italy and there are 205 departures available from sixteen of the world's leading cruise lines.
Filter Results
Departures
Show More...
Duration
4 Days
31 Days
Start & End Cities
Ship Size
Ship Features
Operators
Show More...
Price
$400pp
$38,195pp
Countries
Show More...
Filter Results
102 Cruises (205 Cruise Departures)
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Departures: Jun 2024 to Oct 2026
Countries Visited: Spain, Gibraltar, France, Italy
Exclusive Deal
INSIDE
$1,673
OCEANVIEW
$1,822
BALCONY
$1,980
SUITE
$2,594
From 1,673
Cruise

13 Days (12 Nights) Barcelona to Venice
Cruise Line: Viking Cruises
Departures: Aug 2024 to Aug 2026
Countries Visited: Spain, France, Italy, Greece (+1 more), Croatia
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$9,895
SUITE
$15,835
Save 1,372
From 9,895
Cruise
 (1)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Departure: 02 April 2025
Countries Visited: Spain, France, Corsica, Italy
INSIDE
$3,166
OCEANVIEW
$3,713
BALCONY
$4,230
SUITE
$5,782
From 3,166
Cruise
 (1)

13 Days (12 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Departure: 21 April 2025
Countries Visited: Spain, France, Italy, Montenegro (+2 more), Croatia, Slovenia
INSIDE
$4,134
OCEANVIEW
$5,026
BALCONY
$6,061
SUITE
$7,441
From 4,134
Cruise
 (2)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Departure: 06 May 2025
Countries Visited: Spain, France, Monaco, Italy
Exclusive Deal
INSIDE
$4,129
OCEANVIEW
$4,357
BALCONY
$6,109
SUITE
$12,287
Save 2,031
From 4,129
Cruise
 (1)

12 Days (11 Nights) Barcelona to Venice
Cruise Line: Holland America
Ship: Oosterdam
Departure: 10 September 2025
Countries Visited: Spain, France, Italy, Greece (+2 more), Croatia, Montenegro
Have It All Offer
INSIDE
$3,941
OCEANVIEW
$4,139
BALCONY
$5,278
SUITE
$7,159
From 3,941
Cruise
 (3)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Departure: 04 March 2025
Countries Visited: Spain, Gibraltar, Corsica, Italy
Exclusive Deal
INSIDE
$1,374
OCEANVIEW
-
BALCONY
$1,489
SUITE
$1,929
From 1,374
Cruise
 (1)

5 Days (4 Nights) Barcelona to Rome
Departures: Jul 2024 to Sep 2024
Countries Visited: Spain, France, Italy
INSIDE
$1,439
OCEANVIEW
$1,637
BALCONY
$1,944
SUITE
$2,051
From 1,439
Cruise
 (1)

13 Days (12 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Departure: 06 September 2025
Countries Visited: Spain, France, Monaco, Italy (+3 more), Montenegro, Croatia, Slovenia
INSIDE
$5,915
OCEANVIEW
$6,405
BALCONY
$7,095
SUITE
$9,394
From 5,915
Cruise
 (1)

11 Days (10 Nights) Barcelona to Venice
Departure: 23 June 2024
Countries Visited: Spain, France, Italy, Sicily (+2 more), Greece, Croatia
INSIDE
$2,324
OCEANVIEW
-
BALCONY
-
SUITE
-
From 2,324
Cruise
 (1)

23 Days (22 Nights) Malaga to Rome
Cruise Line: Oceania Cruises
Departure: 07 October 2025
Countries Visited: Spain, Morocco, Portugal, Tunisia (+4 more), Malta, Greece, Sicily, Italy
Exclusive Deal
INSIDE
$9,807
OCEANVIEW
$10,569
BALCONY
$15,608
SUITE
$21,152
Save 2,073
From 9,807
Cruise
 (2)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 02 October 2025
Countries Visited: Spain, France, Italy
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$8,301
SUITE
$13,907
Save 159
From 8,301
Cruise
 (1)

12 Days (11 Nights) Barcelona to Venice
Departures: Sep 2024 to Sep 2025
Countries Visited: Spain, France, Italy, Sicily (+3 more), Malta, Greece, Croatia
Exclusive Solo Offer
INSIDE
$3,982
OCEANVIEW
$4,670
BALCONY
$5,818
SUITE
$6,123
From 3,982
Cruise
 (1)

11 Days (10 Nights) Barcelona to Venice
Departure: 11 August 2024
Countries Visited: Spain, France, Italy, Sicily (+3 more), Malta, Greece, Croatia
INSIDE
$3,028
OCEANVIEW
$3,486
BALCONY
$3,562
SUITE
$4,175
From 3,028
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Departures: Jul 2024 to Sep 2024
Countries Visited: Spain, Sardinia, Corsica, Sicily (+1 more), Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$2,328
BALCONY
$2,674
SUITE
$5,149
From 2,328
Cruise

21 Days (20 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Ovation
Departures: May 2025 to Oct 2025
Countries Visited: Spain, France, Gibraltar, Morocco (+4 more), Monaco, Italy, Corsica, Sardinia
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$15,755
SUITE
$28,714
From 15,755
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Royal Caribbean
Departures: Jul 2024 to Sep 2024
Countries Visited: Spain, France, Corsica, Italy
Exclusive Deal
INSIDE
$2,464
OCEANVIEW
$2,340
BALCONY
$3,387
SUITE
$5,366
Save 2,039
From 2,340
Cruise

10 Days (9 Nights) Santa Cruz de Tenerife to Bari
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 23 March 2025
Countries Visited: Spain, Morocco, Sicily, Greece (+1 more), Italy
Save And Sail Offer
INSIDE
$1,748
OCEANVIEW
$2,194
BALCONY
$3,382
SUITE
$5,213
From 1,748
Cruise

29 Days (28 Nights) Barcelona to Rome
Cruise Line: Cunard
Departure: 07 September 2026
Countries Visited: Spain, Corsica, Sicily, Italy (+3 more), France, Greece, Turkey
Exclusive Deal
INSIDE
$4,909
OCEANVIEW
$5,305
BALCONY
$6,097
SUITE
$17,829
From 4,909
Cruise

6 Days (5 Nights) Barcelona to Ravenna
Cruise Line: Royal Caribbean
Departure: 12 May 2025
Countries Visited: Spain, Corsica, Italy, Sicily
Exclusive Deal
INSIDE
$1,531
OCEANVIEW
$1,953
BALCONY
$2,026
SUITE
$3,224
Save 524
From 1,284
Cruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 03 November 2024
Countries Visited: Spain, France, Italy, Corsica (+1 more), Sardinia
INSIDE
$3,441
OCEANVIEW
$4,152
BALCONY
$4,152
SUITE
-
From 3,441
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Departure: 07 July 2025
Countries Visited: Spain, Corsica, France, Italy
Exclusive Deal
INSIDE
$1,486
OCEANVIEW
$1,734
BALCONY
$2,080
SUITE
$4,258
From 1,486
Cruise

7 Days (6 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 19 March 2026
Countries Visited: Spain, Gibraltar, France, Italy
Exclusive Deal
INSIDE
$1,466
OCEANVIEW
$1,704
BALCONY
$1,852
SUITE
$2,466
From 1,466
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Departure: 01 March 2026
Countries Visited: Spain, Gibraltar, France, Italy
Exclusive Deal
INSIDE
$1,724
OCEANVIEW
$1,803
BALCONY
$2,338
SUITE
$2,872
From 1,724
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Departure: 30 August 2025
Countries Visited: Spain, Malta, Greece, Turkey (+1 more), Italy
Exclusive DealExclusive Offer
INSIDE
$2,350
OCEANVIEW
$2,597
BALCONY
$3,029
SUITE
$9,303
Save 3,505
From 2,350
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Departures: Sep 2024 to Oct 2024
Countries Visited: Spain, France, Corsica, Italy (+2 more), Malta, Sicily
Exclusive DealExclusive Offer
INSIDE
$2,584
OCEANVIEW
$3,641
BALCONY
$3,634
SUITE
$9,798
Save 3,676
From 2,584
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Departure: 18 August 2025
Countries Visited: Spain, Malta, Italy, Croatia (+2 more), Montenegro, Greece
Exclusive Deal
INSIDE
$2,875
OCEANVIEW
$3,122
BALCONY
$3,568
SUITE
$8,518
From 2,875
Cruise

31 Days (30 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Ovation
Departure: 15 April 2025
Countries Visited: Spain, Sardinia, France, Italy (+4 more), Monaco, Sicily, Malta, Corsica
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$24,432
SUITE
-
From 24,432
Cruise

7 Days (6 Nights) Santa Cruz de Tenerife to Genoa
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 07 November 2024
Countries Visited: Spain, Portugal, France, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$1,159
SUITE
-
From 1,159
Cruise

5 Days (4 Nights) Tarragona to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 31 October 2024
Countries Visited: Spain, Sardinia, Italy
Exclusive Deal
INSIDE
$558
OCEANVIEW
$667
BALCONY
$815
SUITE
$1,508
From 558
Results: 1-30 of 102

No Results found. Try changing your search filters.