Cruises from Spain to Italy

Are you looking for a cruise from Spain to Italy? September is the most popular month to cruise between Spain and Italy and there are 381 departures available from eighteen of the world's leading cruise lines.
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188 Cruises (381 Departures)
188 Cruises (381 Departures)
Departures
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Duration
3 Days
29 Days
Start & End Cities
Ship Size
Ship Features
Operators
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Price
$200pp
$41,750pp
Countries
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Cruise
 (1)

13 Days (12 Nights) Barcelona to Venice
Operator: Viking
Departures: Feb 2027 to Jun 2029
Visits: Spain, France, Italy, Greece, Croatia
Exclusive Savings
Balcony
$11,069
Suite
$15,283
From (Per Person)
A$11,069
Save 316
Per Person
Cruise
 (3)

5 Days (4 Nights) Barcelona to Rome
Operator: MSC Cruises
Departure: 24 April 2027
Visits: Spain, France, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$2,624
From (Per Person)
A$2,624
Per Person
Cruise
 (13)

15 Days (14 Nights) Barcelona to Trieste
Operator: Cunard
Departure: 25 August 2028
Visits: Spain, France, Italy, Malta, Croatia
Exclusive Savings
Inside
$3,340
Oceanview
$3,716
Balcony
$4,083
Suite
$7,795
From (Per Person)
A$3,340
Per Person
Cruise
 (4)

10 Days (9 Nights) Barcelona to Rome
Operator: Oceania
Departure: 13 September 2028
Visits: Spain, France, Monaco, Italy +4 more, Corsica, Sardinia, Sicily, Malta
Your World Inclusions
Exclusive Savings
Inside
$4,387
Oceanview
$5,289
Balcony
$6,269
Suite
$8,975
From (Per Person)
A$4,387
Save 2,123
Per Person
Cruise
 (9)

12 Days (11 Nights) Barcelona to Rome
Operator: Azamara
Departure: 20 February 2027
Visits: Spain, Sardinia, Tunisia, Malta, Sicily, Italy
Azamara Always Included
Exclusive Savings
Inside
$3,209
Oceanview
$4,963
Balcony
$6,501
Suite
$6,501
From (Per Person)
A$3,209
Per Person
Cruise
 (1)

7 Days (6 Nights) Barcelona to Trieste
Operator: MSC Cruises
Departure: 16 April 2027
Visits: Spain, Corsica, Italy, Greece
Exclusive Savings
Inside
$997
Oceanview
$1,265
Balcony
$1,383
Suite
$2,007
From (Per Person)
A$997
Per Person
Cruise
 (3)

15 Days (14 Nights) Barcelona to Rome
Operator: Holland America
Ship: Oosterdam
Departure: 28 August 2027
Visits: Spain, Malta, Greece, Turkey, Montenegro, Sicily, Italy
Exclusive Savings
Inside
$3,926
Oceanview
$4,510
Balcony
$5,193
Suite
$8,836
From (Per Person)
A$3,926
Per Person
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Operator: Oceania
Departure: 16 September 2027
Visits: Spain, France, Monaco, Italy, Corsica, Sardinia, Sicily
Your World Inclusions
Exclusive Savings
Inside
$3,512
Oceanview
$3,661
Balcony
$5,637
Suite
$10,450
From (Per Person)
A$3,512
Save 3,598
Per Person
Cruise
 (1)

10 Days (9 Nights) Barcelona to Bologna
Departure: 24 September 2027
Visits: Spain, France, Italy, Sicily, Greece, Montenegro, Croatia
Just Cruise Fare
Exclusive Savings
Inside
$4,638
Oceanview
$5,115
Balcony
$6,365
Suite
$8,002
From (Per Person)
A$4,638
Per Person
Cruise
 (13)

8 Days (7 Nights) Barcelona to Trieste
Operator: Cunard
Departures: Aug 2027 to Sep 2027
Visits: Spain, Malta, Montenegro, Croatia, Italy
Exclusive Savings
Inside
$1,744
Oceanview
$1,932
Balcony
$2,338
Suite
$4,080
From (Per Person)
A$1,744
Per Person
Cruise
 (13)

15 Days (14 Nights) Barcelona to Rome
Operator: Cunard
Departure: 10 September 2027
Visits: Spain, Malta, Montenegro, Croatia, Italy, Greece, Sicily
Exclusive Savings
Inside
$3,994
Oceanview
$4,152
Balcony
-
Suite
-
From (Per Person)
A$3,994
Per Person
Cruise
 (4)

10 Days (9 Nights) Barcelona to Venice
Operator: Oceania
Departure: 21 June 2027
Visits: Spain, France, Italy, Sicily, Greece, Montenegro, Croatia
Your World Inclusions
Exclusive Savings
Inside
$2,930
Oceanview
$2,971
Balcony
$4,216
Suite
$9,068
From (Per Person)
A$2,930
Save 4,040
Per Person
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Operator: Explora Journeys
Ship: Explora II
Departure: 16 October 2028
Visits: Spain, France, Monaco, Italy
Exclusive Savings
Suite
$5,713
From (Per Person)
A$5,713
Save 117
Per Person
Cruise
 (13)

22 Days (21 Nights) Barcelona to Rome
Operator: Cunard
Departure: 11 June 2027
Visits: Spain, Corsica, Italy, Malta +4 more, Montenegro, Croatia, Greece, Sicily
Exclusive Savings
Inside
$4,610
Oceanview
$5,055
Balcony
$6,837
Suite
$10,995
From (Per Person)
A$4,610
Per Person
Cruise
 (3)

22 Days (21 Nights) Barcelona to Trieste
Operator: Holland America
Departure: 04 May 2028
Visits: Spain, France, Italy, Sicily +4 more, Greece, Turkey, Albania, Croatia
Exclusive Savings
Inside
$6,038
Oceanview
$6,632
Balcony
$8,641
Suite
$11,611
From (Per Person)
A$6,038
Per Person
Cruise
 (6)

17 Days (16 Nights) Barcelona to Rome
Operator: Azamara
Departure: 23 September 2028
Visits: Spain, France, Corsica, Italy, Sardinia
Azamara Always Included
Exclusive Savings
Inside
$8,012
Oceanview
$8,669
Balcony
$10,609
Suite
$14,941
From (Per Person)
A$8,012
Per Person
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Departure: 17 October 2027
Visits: Spain, Tunisia, Malta, Sicily, Italy
Just Cruise Fare
Exclusive Savings
Inside
$2,183
Oceanview
-
Balcony
$2,971
Suite
$3,269
From (Per Person)
A$2,183
Per Person
Cruise
 (1)

10 Days (9 Nights) Barcelona to Bologna
Departure: 30 July 2027
Visits: Spain, France, Italy, Sicily, Greece, Montenegro, Croatia
Just Cruise Fare
Exclusive Savings
Inside
$4,727
Oceanview
$4,876
Balcony
$5,948
Suite
$7,363
From (Per Person)
A$4,727
Per Person
Cruise
 (1)

10 Days (9 Nights) Barcelona to Rome
Operator: Silversea
Ship: Silver Nova
Departure: 01 November 2028
Visits: Spain, Malta, Sicily, Italy
Exclusive Savings
Balcony
$7,680
Suite
$11,355
From (Per Person)
A$7,680
Save 2,770
Per Person
Cruise
 (6)

9 Days (8 Nights) Barcelona to Rome
Operator: Azamara
Departure: 15 September 2028
Visits: Spain, France, Monaco, Italy
Azamara Always Included
Exclusive Savings
Inside
$3,631
Oceanview
$3,915
Balcony
$4,797
Suite
$6,708
From (Per Person)
A$3,631
Per Person
Cruise
 (13)

15 Days (14 Nights) Barcelona to Trieste
Operator: Cunard
Departure: 15 September 2028
Visits: Spain, France, Corsica, Italy, Malta, Croatia
Exclusive Savings
Inside
$3,340
Oceanview
$3,716
Balcony
$4,380
Suite
$8,171
From (Per Person)
A$3,340
Per Person
Cruise
 (6)

9 Days (8 Nights) Barcelona to Rome
Operator: Azamara
Departure: 21 April 2028
Visits: Spain, France, Monaco, Italy
Azamara Always Included
Exclusive Savings
Inside
$4,801
Oceanview
$5,193
Balcony
$6,349
Suite
$8,877
From (Per Person)
A$4,801
Per Person
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Operator: Celebrity Cruises
Departures: Jun 2027 to Aug 2027
Visits: Spain, Morocco, Portugal, Corsica, Italy
Exclusive Savings
Inside
$2,185
Oceanview
$2,545
Balcony
$2,795
Suite
$8,100
From (Per Person)
A$2,185
Save 1,620
Per Person
Cruise
 (13)

22 Days (21 Nights) Barcelona to Trieste
Operator: Cunard
Departure: 01 October 2027
Visits: Spain, Sicily, Greece, Turkey, Italy, Croatia
Exclusive Savings
Inside
$4,570
Oceanview
$5,204
Balcony
$6,689
Suite
$11,510
From (Per Person)
A$4,570
Per Person
Cruise
 (1)

17 Days (16 Nights) Barcelona to Rome
Operator: Explora Journeys
Ship: Explora II
Departure: 29 April 2028
Visits: Spain, Portugal, Tunisia, Malta, Sicily, Italy
Exclusive Savings
Suite
$19,404
From (Per Person)
A$19,404
Save 396
Per Person
Cruise
 (2)

9 Days (8 Nights) Santa Cruz De Tenerife to Rome
Operator: MSC Cruises
Departures: Apr 2027 to Mar 2028
Visits: Spain, Morocco, Italy
Exclusive Savings
Inside
$1,014
Oceanview
$1,252
Balcony
$1,281
Suite
$2,281
From (Per Person)
A$1,014
Per Person
Cruise
 (1)

19 Days (18 Nights) Barcelona to Rome
Operator: Explora Journeys
Ship: Explora II
Departure: 28 December 2026
Visits: Spain, France, Italy, Sicily, Malta, Tunisia
Exclusive Savings
Suite
$19,551
From (Per Person)
A$19,551
Save 399
Per Person
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Operator: Explora Journeys
Ship: Explora II
Departures: May 2028 to Oct 2028
Visits: Spain, Tunisia, Malta, Sicily, Italy
Exclusive Savings
Suite
$5,865
From (Per Person)
A$5,865
Save 135
Per Person
Cruise
 (1)

10 Days (9 Nights) Barcelona to Venice
Operator: Oceania
Departure: 24 March 2028
Visits: Spain, Sardinia, Sicily, Greece, Croatia, Italy
Your World Inclusions
Exclusive Savings
Inside
$3,578
Oceanview
$3,918
Balcony
$6,032
Suite
$8,622
From (Per Person)
A$3,578
Save 2,072
Per Person
Cruise
 (1)

9 Days (8 Nights) Barcelona to Rome
Operator: Explora Journeys
Ship: Explora II
Departures: Jun 2028 to Aug 2028
Visits: Spain, Sardinia, Italy, Monaco, France
Exclusive Savings
Suite
$6,169
From (Per Person)
A$6,169
Save 135
Per Person
Results: 1-30 of 188

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