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Cruises from Barcelona to Rome

Are you looking for a cruise from Barcelona to Rome? September is the most popular month to cruise between Barcelona and Rome and there are 235 departures available from seventeen of the world's leading cruise lines.
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106 Cruises (235 Cruise Departures)
8 Day Western Mediterranean with Italy with Princess
Cruise
 (6)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departures: Oct 2026 to Oct 2027
Visit: Spain, France, Corsica, Italy
Princess Standard
Sanctuary Collection
Inside
$1,225
Oceanview
$1,375
Balcony
$1,550
Suite
$1,825
From
US$1,225
Per Person
View Trip
8 Day Western Mediterranean with Italy with Princess
Cruise
 (6)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 02 May 2027
Visit: Spain, France, Corsica, Italy
Princess Standard
Sanctuary Collection
Inside
$1,235
Oceanview
$1,435
Balcony
$1,610
Suite
$1,985
From
US$1,235
Per Person
View Trip
11 Day Barcelona to Rome with Silversea
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Muse
Departure: 24 January 2026
Visit: Spain, Sardinia, Malta, Tunisia, Sicily, Italy
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,810
Suite
$6,860
From
US$5,810
Save 2,490
Per Person
View Trip
10 Day Mediterranean Horizons with Regent Seven Seas
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 07 October 2027
Visit: Spain, France, Italy, Corsica, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,599
Suite
$8,999
From
US$8,599
Save 13,599
Per Person
View Trip
11 Day Italian Celebration with Regent Seven Seas
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 15 May 2027
Visit: Spain, France, Monaco, Italy, Sicily, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$7,599
Suite
$8,649
From
US$7,599
Save 13,599
Per Person
View Trip
12 Day Spain & Italy Cruise: Barcelona, Salerno & Rome with Azamara Cruises
Cruise
 (6)

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 20 February 2027
Visit: Spain, Sardinia, Tunisia, Malta, Sicily, Italy
Azamara Always Included
Inside
$3,429
Oceanview
$4,009
Balcony
$4,599
Suite
$7,169
From
US$3,429
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 02 May 2027
Visit: Spain, Malta, Tunisia, Sicily, Italy
Inside
-
Oceanview
-
Balcony
-
Suite
$3,879
From
US$3,879
Per Person
View Trip
15 Day Mediterranean, Greece And Turkey with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 01 October 2027
Visit: Spain, Sicily, Greece, Turkey, Italy
Inside
$2,859
Oceanview
$3,209
Balcony
$3,609
Suite
$8,259
From
US$2,859
Per Person
View Trip
11 Day Fall In The Roman Empire with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 08 October 2027
Visit: Spain, France, Monaco, Italy
Your World Inclusions
Exclusive Savings
Inside
$3,099
Oceanview
$3,949
Balcony
$4,699
Suite
$6,699
From
US$3,099
Save 3,099
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise
 (2)

4 Days (3 Nights) Barcelona to Rome
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 07 November 2025
Visit: Spain, France, Italy
Inside
-
Oceanview
$349
Balcony
-
Suite
-
From
US$349
Per Person
View Trip
10 Day Western Med: Barcelona to Rome with Virgin Voyages
Cruise
 (5)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Virgin Voyages
Ship: Resilient Lady
Departure: 08 August 2027
Visit: Spain, France, Italy, Sicily, Malta
Set, Sail and Save Offer
Inside
$2,016
Oceanview
$2,287
Balcony
$2,511
Suite
$5,715
From
US$2,016
Per Person
View Trip
11 Day Spain, Portugal & Morocco with Celebrity Cruises
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 18 September 2027
Visit: Spain, Morocco, Portugal, Sardinia, Italy
Exclusive Savings
Inside
$1,776
Oceanview
$1,997
Balcony
$2,090
Suite
$5,115
From
US$1,776
Save 1,039
Per Person
View Trip
10 Day Epicurean Odyssey with Oceania Cruises
Cruise
 (1)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 27 September 2027
Visit: Spain, France, Monaco, Italy, Corsica, Sardinia
Your World Inclusions
Exclusive Savings
Inside
$2,499
Oceanview
$2,749
Balcony
$4,299
Suite
$6,299
From
US$2,499
Save 2,499
Per Person
View Trip
11 Day Greek Isles & Malta Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Apr 2026 to Oct 2027
Visit: Spain, Malta, Greece, Turkey, Italy
Exclusive Savings
Inside
$1,658
Oceanview
$1,858
Balcony
$2,131
Suite
$5,179
From
US$1,658
Save 1,043
Per Person
View Trip
15 Day Malta, Greece & Amalfi Coast Collectors' Voyage with Holland America
Cruise
 (2)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Holland America
Ship: Oosterdam
Departures: Jul 2026 to Aug 2027
Visit: Spain, Malta, Greece, Turkey, Montenegro, Sicily, Italy
Book Early & Have It All Fare Option
Inside
$2,204
Oceanview
$2,404
Balcony
$3,254
Suite
$4,054
From
US$2,204
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (13)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 11 June 2027
Visit: Spain, Corsica, Italy
Inside
$1,389
Oceanview
$1,489
Balcony
$1,739
Suite
$4,139
From
US$1,389
Per Person
View Trip
8 Day Western Mediterranean with Italy with Princess
Cruise
 (6)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departures: Apr 2026 to Apr 2027
Visit: Spain, France, Corsica, Italy
Princess Standard
Sanctuary Collection
Inside
$1,134
Oceanview
$1,314
Balcony
$1,574
Suite
$1,844
From
US$1,134
Per Person
View Trip
12 Day Best Of Italy, France & Spain with Celebrity Cruises
Cruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Constellation
Departure: 24 May 2027
Visit: Spain, Corsica, France, Italy, Sicily
Exclusive Savings
Inside
$1,881
Oceanview
$2,023
Balcony
$2,242
Suite
$5,172
From
US$1,881
Save 1,079
Per Person
View Trip
11 Day Spain, Portugal & Morocco with Celebrity Cruises
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Jun 2027 to Aug 2027
Visit: Spain, Morocco, Portugal, Corsica, Italy
Exclusive Savings
Inside
$1,428
Oceanview
$1,649
Balcony
$1,742
Suite
$4,767
From
US$1,428
Save 1,050
Per Person
View Trip
11 Day A Journey Of Unique Architecture Seamlessely Blending Culture & Scenic Beauty with Explora Journeys
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 03 May 2026
Visit: Spain, Gibraltar, Colombia, France, Monaco, Italy
Sky & Sea
Inside
-
Oceanview
-
Balcony
$7,605
Suite
$8,755
From
US$7,605
Per Person
View Trip
8 Day A Journey of Riviera Starlets & Napoleon's Corsica with Explora Journeys
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 06 October 2025
Visit: Spain, France, Sardinia, Corsica, Italy
Inside
-
Oceanview
-
Balcony
-
Suite
$10,400
From
US$10,400
Per Person
View Trip
11 Day Radiant Rivieras with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 05 November 2026
Visit: Spain, France, Monaco, Italy
Your World Inclusions
Fall Upgrade Offer
Exclusive Savings
Inside
$3,299
Oceanview
$4,049
Balcony
$4,049
Suite
$5,499
From
US$3,299
Save 3,299
Per Person
View Trip
13 Day Mediterranean Nights with Regent Seven Seas
Cruise

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 28 September 2026
Visit: Spain, France, Italy, Malta
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,049
Suite
$11,999
From
US$11,049
Save 16,449
Per Person
View Trip
8 Day Western Mediterranean with Italy with Princess
Cruise
 (6)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departures: May 2026 to Jul 2026
Visit: Spain, France, Corsica, Italy
Princess Standard
Sanctuary Collection
Inside
$1,264
Oceanview
$1,544
Balcony
$1,869
Suite
$2,274
From
US$1,264
Per Person
View Trip
11 Day Croissants & Cannoli with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 16 September 2027
Visit: Spain, France, Monaco, Italy, Corsica, Sardinia, Sicily
Your World Inclusions
Exclusive Savings
Inside
$2,999
Oceanview
$3,249
Balcony
$4,999
Suite
$7,099
From
US$2,999
Save 2,999
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 17 October 2027
Visit: Spain, Tunisia, Malta, Sicily, Italy
Inside
-
Oceanview
-
Balcony
-
Suite
$3,639
From
US$3,639
Per Person
View Trip
27 Day Ramblas To Renaissance with Oceania Cruises
Cruise
 (3)

27 Days (26 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 09 December 2026
Visit: Spain, Gibraltar, Morocco, Portugal, France, Italy, Corsica
Your World Inclusions
Exclusive Savings
Inside
$7,199
Oceanview
$7,899
Balcony
$11,999
Suite
$16,699
From
US$7,199
Save 7,199
Per Person
View Trip
8 Day Mediterranean Cruise: Spain, France & Italy with Azamara Cruises
Cruise
 (6)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 28 November 2026
Visit: Spain, France, Italy
Azamara Always Included
Inside
$1,769
Oceanview
$2,029
Balcony
$2,339
Suite
$3,999
From
US$1,769
Per Person
View Trip
8 Day Elegant Shores with Regent Seven Seas
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 10 April 2026
Visit: Spain, France, Italy, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,999
Suite
$6,099
From
US$4,999
Save 9,399
Per Person
View Trip
10 Day Toast To Toulon with Regent Seven Seas
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 31 August 2027
Visit: Spain, France, Italy, Sardinia
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$8,199
Suite
$8,599
From
US$8,199
Save 13,199
Per Person
View Trip
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