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Cruises from Barcelona to Rome

Are you looking for a cruise from Barcelona to Rome? September is the most popular month to cruise between Barcelona and Rome and there are 191 departures available from sixteen of the world's leading cruise lines.
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90 Cruises (191 Cruise Departures)
12 Day Enchanted Evenings with Regent Seven Seas
Cruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 18 September 2026
Countries Visited: Spain, Monaco, Italy
Early Booking Saving
INSIDE
-
OCEANVIEW
-
BALCONY
$9,599
SUITE
$11,299
Save (per person) 14,999
From (per person) 9,599
View Trip
8 Day A Journey From Elegance & Cultural Essence To Glamour & Antiquities with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 14 September 2026
Countries Visited: Spain, Sardinia, Corsica, France (+1 more), Italy
Best Available Fare
INSIDE
-
OCEANVIEW
-
BALCONY
$5,565
SUITE
$6,415
From (per person) 5,565
View Trip
8 Day Luminous Mediterranean with Oceania Cruises
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 31 October 2026
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$2,999
SUITE
$4,699
Save (per person) 2,999
From (per person) 2,999
View Trip
11 Day Greek Isles & Turkey Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Jun 2025 to Oct 2025
Countries Visited: Spain, Greece, Turkey, Italy
Bonus Onboard CreditExciting Deals
INSIDE
$1,746
OCEANVIEW
$2,905
BALCONY
$1,965
SUITE
$5,015
Save (per person) 1,789
From (per person) 1,746
View Trip
9 Day Spain & Italy Cruise: Barcelona, Portofino & Florence with Azamara Cruises
Cruise
 (1)

9 Days (8 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 09 April 2026
Countries Visited: Spain, France, Italy
INSIDE
$2,079
OCEANVIEW
$2,269
BALCONY
$2,759
SUITE
$4,299
From (per person) 2,079
View Trip
8 Day Mediterranean Cruise: Spain, France & Italy with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 28 November 2026
Countries Visited: Spain, France, Italy
INSIDE
$1,729
OCEANVIEW
$1,999
BALCONY
$2,559
SUITE
$3,999
From (per person) 1,729
View Trip
8 Day A Journey of Golden Ibiza Days & Warm Riviera Nights with Explora Journeys
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 25 August 2025
Countries Visited: Spain, France, Italy
Best Available Fare
INSIDE
-
OCEANVIEW
-
BALCONY
$4,815
SUITE
$6,255
From (per person) 4,815
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Countries Visited: Spain, Corsica, Sicily, Italy (+1 more), France
Exclusive Deal
INSIDE
$1,919
OCEANVIEW
$2,169
BALCONY
$2,739
SUITE
$7,619
From (per person) 1,919
View Trip
8 Day A Journey to White Isle Bohemia & Italian Riviera Romance with Explora Journeys
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jun 2025 to Sep 2025
Countries Visited: Spain, France, Italy
Best Available Fare
INSIDE
-
OCEANVIEW
-
BALCONY
$4,320
SUITE
$6,315
From (per person) 4,320
View Trip
11 Day Greek Isles & Turkey Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 23 August 2025
Countries Visited: Spain, Turkey, Greece, Italy
Exciting DealsBonus Onboard Credit
INSIDE
$1,408
OCEANVIEW
-
BALCONY
$2,089
SUITE
-
Save (per person) 1,100
From (per person) 1,408
View Trip
8 Day Mediterranean with Total Solar Eclipse with Princess
Cruise
 (3)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 08 August 2026
Countries Visited: Spain, Gibraltar, Italy
Exclusive DealBonus Instant Savings
INSIDE
$2,110
OCEANVIEW
$2,840
BALCONY
$3,560
SUITE
$3,910
From (per person) 2,110
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2026 to Oct 2026
Countries Visited: Spain, France, Italy, Sicily
INSIDE
$1,019
OCEANVIEW
$1,519
BALCONY
$1,499
SUITE
$1,599
From (per person) 1,019
View Trip
8 Day Mediterranean with Princess
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sapphire Princess
Departure: 01 March 2026
Countries Visited: Spain, Gibraltar, France, Italy
Exclusive DealBonus Instant Savings
INSIDE
$770
OCEANVIEW
$814
BALCONY
$1,140
SUITE
$1,220
From (per person) 770
View Trip
21 Day Barcelona to Rome with Silversea
Cruise

21 Days (20 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 28 September 2026
Countries Visited: Spain, France, Monaco, Corsica (+2 more), Italy, Sicily
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$15,200
From (per person) 15,200
View Trip
8 Day Yachting Havens with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 05 May 2026
Countries Visited: Spain, France, Italy
Fleetwide SaleExclusive Deal
INSIDE
$1,980
OCEANVIEW
$2,160
BALCONY
$3,240
SUITE
$4,500
Save (per person) 2,418
From (per person) 1,980
View Trip
11 Day Charmed Rivieras with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 21 April 2026
Countries Visited: Spain, France, Corsica, Sardinia (+1 more), Italy
Fleetwide SaleExclusive Deal
INSIDE
$2,880
OCEANVIEW
$3,195
BALCONY
$4,545
SUITE
$6,300
Save (per person) 3,518
From (per person) 2,880
View Trip
29 Day Mediterranean And Greek Islands with Cunard
Cruise

29 Days (28 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 04 May 2026
Countries Visited: Spain, Greece, Turkey, Sicily (+3 more), France, Italy, Corsica
Exclusive Deal
INSIDE
$3,679
OCEANVIEW
$3,949
BALCONY
$4,869
SUITE
$13,469
From (per person) 3,679
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 15 June 2026
Countries Visited: Spain, France, Italy, Sardinia (+2 more), Corsica, Sicily
Exclusive Deal
INSIDE
$1,939
OCEANVIEW
$2,189
BALCONY
$2,669
SUITE
$6,559
From (per person) 1,939
View Trip
16 Day Barcelona to Civitavecchia with Silversea
Cruise

16 Days (15 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 27 June 2026
Countries Visited: Spain, France, Monaco, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$10,600
From (per person) 10,600
View Trip
28 Day Solar Eclipse Collectors' Voyage: Iberia & Italy with Holland America
Cruise
 (2)

28 Days (27 Nights) Barcelona to Rome
Cruise Line: Holland America
Ship: Oosterdam
Departure: 02 August 2026
Countries Visited: Spain, Morocco, Portugal, Corsica (+4 more), Italy, Montenegro, Greece, Sicily
Exclusive Deal
INSIDE
$5,634
OCEANVIEW
$6,434
BALCONY
-
SUITE
-
From (per person) 5,634
View Trip
22 Day An Extended Journey Through Mediterranean Charm, Rugged Beauty And Iconic Culture with Explora Journeys
Cruise
 (1)

22 Days (21 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 22 September 2025
Countries Visited: Spain, France, Italy, Sicily (+4 more), Tunisia, Monaco, Sardinia, Corsica
Explora Extended Journey SavingBest Available Fare
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$20,805
From (per person) 20,805
View Trip
27 Day Ramblas To Renaissance with Oceania Cruises
Cruise
 (3)

27 Days (26 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 09 December 2026
Countries Visited: Spain, Gibraltar, Morocco, Portugal (+3 more), France, Italy, Corsica
Exclusive Deal
INSIDE
$7,199
OCEANVIEW
$7,899
BALCONY
$11,999
SUITE
$16,699
Save (per person) 7,199
From (per person) 7,199
View Trip
13 Day French & Italian Treasures with Oceania Cruises
Cruise
 (3)

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 30 September 2026
Countries Visited: Spain, France, Italy, Corsica (+3 more), Sardinia, Sicily, Malta
Fleetwide SaleExclusive Deal
INSIDE
$3,599
OCEANVIEW
$3,999
BALCONY
$6,199
SUITE
$8,599
Save (per person) 3,599
From (per person) 3,599
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (13)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 11 June 2027
Countries Visited: Spain, Corsica, Italy
Exclusive Deal
INSIDE
$1,389
OCEANVIEW
$1,489
BALCONY
$1,739
SUITE
$4,139
From (per person) 1,389
View Trip
29 Day Istanbul, Greek Islands And Mediterranean with Cunard
Cruise

29 Days (28 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Countries Visited: Spain, Corsica, Sicily, Italy (+3 more), France, Greece, Turkey
Exclusive Deal
INSIDE
$3,899
OCEANVIEW
$4,219
BALCONY
$5,099
SUITE
$15,939
From (per person) 3,899
View Trip
22 Day An Extended Journey Of Luscious Landscapes And Historic Scenery with Explora Journeys
Cruise
 (1)

22 Days (21 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 08 September 2025
Countries Visited: Spain, Monaco, France, Italy (+3 more), Corsica, Sardinia, Sicily
Explora Extended Journey SavingBest Available Fare
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$26,835
From (per person) 26,835
View Trip
8 Day Costa Brave & Italy with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 29 October 2026
Countries Visited: Spain, France, Corsica, Italy (+1 more), Sardinia
Fleetwide SaleExclusive Deal
INSIDE
$2,099
OCEANVIEW
$2,299
BALCONY
$3,399
SUITE
$4,699
Save (per person) 2,099
From (per person) 2,099
View Trip
22 Day An Extended Journey Of Spectacular Nature And Historic Hotspots with Explora Journeys
Cruise
 (1)

22 Days (21 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 11 August 2025
Countries Visited: Spain, France, Monaco, Corsica (+3 more), Sardinia, Italy, Sicily
Explora Extended Journey SavingBest Available Fare
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$25,335
From (per person) 25,335
View Trip
22 Day Italy, Spain, Greece And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 11 June 2027
Countries Visited: Spain, Corsica, Italy, Malta (+4 more), Montenegro, Croatia, Greece, Sicily
Exclusive Deal
INSIDE
$3,769
OCEANVIEW
$4,119
BALCONY
$5,119
SUITE
$11,419
From (per person) 3,769
View Trip
8 Day A Journey of Riviera Starlets & Napoleon's Corsica with Explora Journeys
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 06 October 2025
Countries Visited: Spain, France, Sardinia, Corsica (+1 more), Italy
Best Available Fare
INSIDE
-
OCEANVIEW
-
BALCONY
$6,030
SUITE
$7,740
From (per person) 6,030
View Trip
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