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Cruises from Barcelona to Rome

Are you looking for a cruise from Barcelona to Rome? September is the most popular month to cruise between Barcelona and Rome and there are 222 departures available from seventeen of the world's leading cruise lines.
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106 Cruises (222 Cruise Departures)
8 Day Mediterranean Cruise: Spain, France & Italy with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 28 November 2026
Visit: Spain, France, Italy
Azamara Always Included
Inside
$1,679
Oceanview
$1,679
Balcony
$1,609
Suite
$2,669
From
US$1,609
Per Person
View Trip
19 Day An Extended Journey From A Riviera New Year To The Mediterranean’s Deep Soul with Explora Journeys
Cruise
 (1)

19 Days (18 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 28 December 2026
Visit: Spain, France, Italy, Sicily, Malta, Tunisia
Inside
-
Oceanview
-
Balcony
-
Suite
$9,715
From
US$9,715
Per Person
View Trip
15 Day Greek Isles: Mykonos & Naples with Holland America
Cruise
 (3)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Holland America
Ship: Oosterdam
Departures: Jun 2027 to Aug 2027
Visit: Spain, Malta, Greece, Turkey, Montenegro, Sicily, Italy
Book Early & Have It All Fare Option
Inside
$2,569
Oceanview
$2,919
Balcony
$3,489
Suite
$5,439
From
US$2,569
Per Person
View Trip
8 Day Western Mediterranean with Italy with Princess
Cruise
 (7)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 05 September 2027
Visit: Spain, France, Italy, Corsica
Princess Standard
Sanctuary Collection
Inside
$1,209
Oceanview
$1,579
Balcony
$1,944
Suite
$2,189
From
US$1,209
Per Person
View Trip
13 Day Total Eclipse of the (Med) with Virgin Voyages
Cruise
 (1)

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 10 August 2026
Visit: Spain, France, Corsica, Italy, Sicily
Inside
$2,388
Oceanview
$2,508
Balcony
$2,628
Suite
$6,588
From
US$2,388
Per Person
View Trip
11 Day Greek Isles & Turkey Cruise with Celebrity Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 15 August 2026
Visit: Spain, Sicily, Greece, Turkey, Italy
Exclusive Savings
Inside
$1,745
Oceanview
$1,852
Balcony
$2,012
Suite
$3,679
From
US$2,055
Save 719
Per Person
View Trip
8 Day A Journey Of Mediterranean Elegance From Secluded Coves To Renaissance Splendour with Explora Journeys
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 18 September 2028
Visit: Spain, Sardinia, Italy, Monaco, France
Inside
-
Oceanview
-
Balcony
-
Suite
$5,050
From
US$5,050
Per Person
View Trip
15 Day Italy, Greece And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 10 September 2027
Visit: Spain, Malta, Montenegro, Croatia, Italy, Greece, Sicily
Bonus Onboard Credit
Value Fare
Inside
$2,219
Oceanview
$2,389
Balcony
$2,879
Suite
$5,999
From
US$2,219
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2026 to Oct 2027
Visit: Spain, France, Italy, Sicily
Inside
$619
Oceanview
$1,679
Balcony
$1,019
Suite
$1,299
From
US$619
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 17 October 2027
Visit: Spain, Tunisia, Malta, Sicily, Italy
Inside
$1,149
Oceanview
-
Balcony
$1,709
Suite
$1,969
From
US$1,149
Per Person
View Trip
8 Day Western Mediterranean with Italy with Princess
Cruise
 (7)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 18 July 2026
Visit: Spain, France, Corsica, Italy
Princess Standard
Princess Premier
Inside
$1,499
Oceanview
$1,649
Balcony
$2,093
Suite
$3,634
From
US$1,499
Per Person
View Trip
22 Day Italy, Spain, Greece And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 11 June 2027
Visit: Spain, Corsica, Italy, Malta (+4 more), Montenegro, Croatia, Greece, Sicily
Bonus Onboard Credit
Value Fare
Inside
$3,029
Oceanview
$3,629
Balcony
$4,319
Suite
$8,639
From
US$3,029
Per Person
View Trip
15 Day Italy, France And Spain with Cunard
Cruise
 (1)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Visit: Spain, Corsica, Sicily, Italy, France
Inside
$2,809
Oceanview
$2,869
Balcony
$3,479
Suite
$5,469
From
US$2,809
Per Person
View Trip
8 Day Mediterranean with Total Solar Eclipse with Princess
Cruise
 (7)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 08 August 2026
Visit: Spain, Gibraltar, Italy
Princess Standard
Inside
$2,179
Oceanview
$2,759
Balcony
$3,229
Suite
$4,275
From
US$2,179
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 02 May 2027
Visit: Spain, Malta, Tunisia, Sicily, Italy
Inside
$1,209
Oceanview
-
Balcony
$1,619
Suite
$1,759
From
US$1,209
Per Person
View Trip
11 Day Spain, Portugal & Morocco with Celebrity Cruises
Cruise
 (1)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 18 September 2027
Visit: Spain, Morocco, Portugal, Sardinia, Italy
Exclusive Savings
Inside
$2,400
Oceanview
$3,135
Balcony
$3,311
Suite
$6,973
From
US$2,841
Save 933
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: Aug 2026 to Sep 2026
Visit: Spain, France, Italy, Sicily
Inside
$879
Oceanview
-
Balcony
$1,129
Suite
$1,479
From
US$879
Per Person
View Trip
8 Day Amalfi Coast, Africa & Iberia with Viking Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Viking Cruises
Ships: Viking Libra, Viking Sea (+2 more), Viking Star, Viking Vela
Departures: Feb 2027 to Mar 2028
Visit: Spain, Sardinia, Tunisia, Sicily, Italy
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$2,899
Suite
$4,299
From
US$2,899
Save 100
Per Person
View Trip
8 Day Mediterranean Holiday with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 06 October 2026
Visit: Spain, France, Italy, Corsica, Sardinia, Sicily
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$3,049
Oceanview
$3,299
Balcony
$4,299
Suite
$5,399
From
US$3,049
Save 3,049
Per Person
View Trip
8 Day Western Mediterranean with Italy with Princess
Cruise
 (7)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departures: Oct 2026 to Oct 2027
Visit: Spain, France, Corsica, Italy
Princess Standard
Sanctuary Collection
Inside
$1,099
Oceanview
$1,439
Balcony
$1,634
Suite
$1,909
From
US$1,099
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2027 to Sep 2027
Visit: Spain, France, Italy, Sicily
Inside
$1,239
Oceanview
-
Balcony
$1,629
Suite
$1,819
From
US$1,239
Per Person
View Trip
15 Day Malta, Greece & Amalfi Coast Collectors' Voyage with Holland America
Cruise
 (3)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Holland America
Ship: Oosterdam
Departure: 26 June 2027
Visit: Spain, Malta, Greece, Turkey, Montenegro, Sicily, Italy
Book Early & Have It All Fare Option
Inside
$2,584
Oceanview
$2,964
Balcony
$3,454
Suite
$5,524
From
US$2,584
Per Person
View Trip
10 Day Italy & Spain Cruise: Florence, Portofino & Barcelona with Azamara Cruises
Cruise
 (8)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 13 August 2026
Visit: Spain, France, Monaco, Italy
Azamara Always Included
Inside
$2,599
Oceanview
$3,069
Balcony
$4,129
Suite
$4,509
From
US$2,599
Per Person
View Trip
8 Day Western Mediterranean with Italy with Princess
Cruise
 (7)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 02 May 2027
Visit: Spain, France, Corsica, Italy
Princess Standard
Sanctuary Collection
Inside
$1,309
Oceanview
$1,579
Balcony
$2,084
Suite
$2,289
From
US$1,309
Per Person
View Trip
11 Day Radiant Rivieras with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 05 November 2026
Visit: Spain, France, Monaco, Italy
Memorial Day Sale
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,025
Suite
$5,215
From
US$4,025
Save 7,473
Per Person
View Trip
8 Day Western Mediterranean From Barcelona To Rome with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 20 September 2026
Visit: Spain, France, Italy, Sicily
Inside
$1,099
Oceanview
-
Balcony
$1,649
Suite
$1,749
From
US$1,099
Per Person
View Trip
8 Day Spain, France & Italy Cruise: Barcelona, Nice & Portovenere with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 02 June 2028
Visit: Spain, France, Italy
Azamara Always Included
Inside
$2,049
Oceanview
$2,329
Balcony
$2,729
Suite
$4,129
From
US$2,049
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Visit: Spain, Corsica, Sicily, Italy
Inside
$1,359
Oceanview
$1,409
Balcony
$1,619
Suite
-
From
US$1,359
Per Person
View Trip
27 Day Ramblas To Renaissance with Oceania Cruises
Cruise
 (1)

27 Days (26 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 09 December 2026
Visit: Spain, Gibraltar, Morocco, Portugal, France, Italy, Corsica
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
$8,099
Balcony
$12,549
Suite
$17,449
From
US$8,099
Save 8,099
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (13)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 15 September 2028
Visit: Spain, France, Corsica, Italy
Cunard Fare
Value Fare
Inside
$1,639
Oceanview
$1,774
Balcony
$2,134
Suite
$4,159
From
US$1,639
Per Person
View Trip
Results: 31-60 of 106

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