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Cruises from Spain to Italy

Are you looking for a cruise from Spain to Italy? August is the most popular month to cruise between Spain and Italy and there are 187 departures available from sixteen of the world's leading cruise lines.
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118 Cruises (187 Cruise Departures)
15 Day Italy And Adriatic with Cunard
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 18 August 2025
Countries Visited: Spain, Malta, Italy, Croatia (+2 more), Montenegro, Greece
INSIDE
$2,766
OCEANVIEW
$3,212
BALCONY
$3,657
SUITE
$7,667
From 2,766
View Trip
25 Day Mediterranean Autumn with Oceania Cruises
Cruise

25 Days (24 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 02 October 2024
Countries Visited: Spain, France, Corsica, Italy (+5 more), Sicily, Greece, Montenegro, Croatia, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$16,777
SUITE
$22,499
Save 2,143
From 16,777
View Trip
21 Day France & Spanish Treasures with Seabourn
Cruise

21 Days (20 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Ovation
Departure: 10 October 2024
Countries Visited: Spain, France, Tunisia, Italy (+2 more), Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$19,324
SUITE
-
From 19,324
View Trip
8 Day Western Mediterranean with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Royal Caribbean
Ship: Voyager of the Seas
Departure: 30 September 2024
Countries Visited: Spain, France, Corsica, Italy
Exclusive Deal
INSIDE
$2,096
OCEANVIEW
$2,137
BALCONY
$2,782
SUITE
$4,842
Save 788
From 1,737
View Trip
31 Day Jewels Of Spain, Italy & France with Seabourn
Cruise

31 Days (30 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Ovation
Departure: 15 April 2025
Countries Visited: Spain, Sardinia, France, Italy (+4 more), Monaco, Sicily, Malta, Corsica
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$28,738
SUITE
-
From 28,738
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Valencia to Genoa
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 25 October 2024
Countries Visited: Spain, Italy
Best Deal Offer
INSIDE
$362
OCEANVIEW
$471
BALCONY
$540
SUITE
-
From 362
View Trip
13 Day Best Of The Med Voyage with Azamara Cruises
Cruise

13 Days (12 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Pursuit
Departure: 13 July 2024
Countries Visited: Spain, France, Monaco, Italy (+3 more), Montenegro, Croatia, Slovenia
INSIDE
$3,424
OCEANVIEW
$3,027
BALCONY
$4,355
SUITE
$7,191
From 3,027
View Trip
13 Day Best Of The Mediterranean Voyage with Azamara Cruises
Cruise

13 Days (12 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 21 April 2025
Countries Visited: Spain, France, Italy, Montenegro (+2 more), Croatia, Slovenia
INSIDE
$5,078
OCEANVIEW
$5,539
BALCONY
$6,229
SUITE
$7,953
From 5,078
View Trip
8 Day Italy, Greece & Croatia with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Ravenna
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 11 May 2024
Countries Visited: Spain, Italy, Sicily, Greece (+2 more), Montenegro, Croatia
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$6,478
Save 3,163
From 6,478
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Royal Caribbean
Ship: Voyager of the Seas
Departures: Jun 2025 to Sep 2025
Countries Visited: Spain, France, Corsica, Italy
Exclusive Deal
INSIDE
$1,745
OCEANVIEW
$2,381
BALCONY
$3,046
SUITE
$3,926
Save 752
From 1,536
View Trip
8 Day Italy, France And Spain with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 July 2025
Countries Visited: Spain, Corsica, France, Italy
INSIDE
$1,516
OCEANVIEW
$1,645
BALCONY
$1,912
SUITE
$3,833
From 1,516
View Trip
8 Day A Journey from Barcelona to Rome with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 09 September 2024
Countries Visited: Spain, France, Corsica, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$7,618
SUITE
$9,261
From 7,618
View Trip
8 Day A Journey From Barcelona To Civitavecchia with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 08 September 2025
Countries Visited: Spain, France, Italy, Corsica (+1 more), Sardinia
The Total Luxury Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$5,846
SUITE
$7,108
From 5,846
View Trip
8 Day A Journey From Barcelona To Civitavecchia with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jun 2025 to Aug 2025
Countries Visited: Spain, France, Italy
The Total Luxury Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$6,192
SUITE
$7,529
From 6,192
View Trip
10 Day Italian Riviera & France with Celebrity Cruises
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 03 October 2024
Countries Visited: Spain, France, Italy
Exclusive Offer
INSIDE
$2,497
OCEANVIEW
$2,672
BALCONY
$2,949
SUITE
$7,133
Save 3,044
From 2,497
View Trip
15 Day France, Italy And Adriatic with Cunard
Cruise

15 Days (14 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 08 September 2025
Countries Visited: Spain, Sardinia, Corsica, Sicily (+4 more), Italy, Greece, Montenegro, Croatia
INSIDE
$2,627
OCEANVIEW
$2,855
BALCONY
$3,301
SUITE
$7,043
From 2,627
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Malaga to Genoa
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 22 April 2025
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$808
SUITE
$2,431
From 808
View Trip
15 Day Italy, Spain And Adriatic with Cunard
Cruise

15 Days (14 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 17 August 2026
Countries Visited: Spain, Sardinia, Sicily, Italy (+3 more), Greece, Montenegro, Croatia
INSIDE
$3,172
OCEANVIEW
$3,518
BALCONY
$4,112
SUITE
$8,518
From 3,172
View Trip
11 Day Barcelona to Rome with Silversea
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Moon
Departure: 16 August 2024
Countries Visited: France, Italy, Spain
Essential FareDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$8,959
BALCONY
$10,543
SUITE
-
From 8,959
View Trip
11 Day Italian Riviera & France with Celebrity Cruises
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 08 June 2024
Countries Visited: Spain, Corsica, Italy, France (+3 more), Sardinia, Malta, Sicily
Exclusive Offer
INSIDE
$2,708
OCEANVIEW
$3,318
BALCONY
$4,079
SUITE
$10,627
Save 3,377
From 2,708
View Trip
8 Day Italy, France And Spain with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Countries Visited: Spain, Corsica, Sicily, Italy
INSIDE
$1,635
OCEANVIEW
$1,783
BALCONY
$1,932
SUITE
$4,258
From 1,635
View Trip
13 Day Vita Est Bona with Regent Seven Seas
Cruise

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 24 August 2024
Countries Visited: Spain, France, Monaco, Italy (+1 more), Sardinia
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$9,523
SUITE
$10,140
Save 10,557
From 9,523
View Trip
13 Day Barcelona to Rome with Silversea
Cruise

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 18 May 2025
Countries Visited: Spain, France, Monaco, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$18,315
From 18,315
View Trip
15 Day Adriatic And Western Mediterranean with Cunard
Cruise

15 Days (14 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departures: May 2026 to Jun 2026
Countries Visited: Spain, Corsica, Sicily, Italy (+3 more), Greece, Montenegro, Croatia
INSIDE
$2,974
OCEANVIEW
$3,320
BALCONY
$3,766
SUITE
$7,924
From 2,974
View Trip
10 Day Canary Islands And Madeira with MSC Cruises
Cruise

10 Days (9 Nights) Santa Cruz de Tenerife to Bari
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 23 March 2025
Countries Visited: Spain, Morocco, Sicily, Greece (+1 more), Italy
Save And Sail Offer
INSIDE
$1,748
OCEANVIEW
$2,194
BALCONY
$4,016
SUITE
$5,213
From 1,748
View Trip
8 Day A Journey From Barcelona To Civitavecchia with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jun 2025 to Sep 2025
Countries Visited: Spain, France, Italy
The Total Luxury Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$5,846
SUITE
$7,108
From 5,846
View Trip
11 Day Mediterranean Jewels & Malta with Seabourn
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Ovation
Departure: 20 October 2024
Countries Visited: Spain, Tunisia, Italy, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,701
SUITE
$21,294
From 10,701
View Trip
8 Day Italy And Spain with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 17 August 2026
Countries Visited: Spain, Sardinia, Sicily, Italy
INSIDE
$1,684
OCEANVIEW
$1,882
BALCONY
$2,080
SUITE
$4,654
From 1,684
View Trip
Results: 91-118 of 118

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