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Cruises from Santa Cruz de Tenerife

Choose from 18 unique cruises starting in Santa Cruz de Tenerife, and travelling to Lisbon, Malaga, Rome and Valletta. February and March are the most popular months to join a cruise from Santa Cruz de Tenerife and you can select from 94 departures available from four leading cruise lines.
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18 Cruises (94 Departures)
18 Cruises (94 Departures)
Departures
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Duration
6 Days
20 Days
Countries Visited
Start & End Cities
Ship Features
Operators
Price
$700pp
$7,860pp
Countries
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14 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise
 (1)

14 Days (13 Nights) Santa Cruz de Tenerife to Valletta
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 19 March 2027
Visits: Spain, Gibraltar, Italy, Sicily, Malta
Bonus Onboard Spend
Exclusive Savings
Inside
$1,823
Oceanview
$2,316
Balcony
$3,242
Suite
$5,033
From (Per Person)
A$1,823
Per Person
View Trip
10 Day Volcanic Islands and Historic Cities of the North Atlantic with Ponant
Cruise
 (2)

10 Days (9 Nights) Santa Cruz De Tenerife to Lisbon
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 13 April 2027
Visits: Spain, Portugal, Morocco
Exclusive Savings
Balcony
$7,644
Suite
$11,534
From (Per Person)
A$7,644
Save 216
Per Person
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Santa Cruz De Tenerife to Santa Cruz De Tenerife
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 27 December 2026
Visits: Spain, Portugal
Exclusive Savings
Inside
$2,548
Oceanview
$2,825
Balcony
$3,003
Suite
$3,726
From (Per Person)
A$2,548
Per Person
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise
 (1)

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Oct 2026 to Mar 2027
Visits: Spain, Portugal
Bonus Onboard Spend
Exclusive Savings
Inside
$829
Oceanview
$1,057
Balcony
$1,509
Suite
$2,623
From (Per Person)
A$829
Per Person
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise
 (1)

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Oct 2026 to Mar 2027
Visits: Spain, Portugal
Bonus Onboard Spend
Exclusive Savings
Inside
$2,089
Oceanview
$2,361
Balcony
$3,025
Suite
$4,366
From (Per Person)
A$2,089
Per Person
View Trip
20 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise
 (1)

20 Days (19 Nights) Santa Cruz De Tenerife to Valletta
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 13 March 2027
Visits: Spain, Portugal, Gibraltar, Italy, Sicily, Malta
Bonus Onboard Spend
Exclusive Savings
Inside
$2,483
Oceanview
$3,410
Balcony
$4,052
Suite
-
From (Per Person)
A$2,483
Per Person
View Trip
13 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise
 (1)

13 Days (12 Nights) Santa Cruz de Tenerife to Valletta
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 20 March 2027
Visits: Spain, Gibraltar, Italy, Sicily, Malta
Bonus Onboard Spend
Exclusive Savings
Inside
$1,805
Oceanview
$1,941
Balcony
$2,788
Suite
-
From (Per Person)
A$1,805
Per Person
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise
 (1)

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Nov 2026 to Nov 2027
Visits: Spain, Portugal
Bonus Onboard Spend
Exclusive Savings
Inside
$829
Oceanview
$1,057
Balcony
$1,564
Suite
$2,323
From (Per Person)
A$829
Per Person
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise
 (1)

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Oct 2026 to Mar 2027
Visits: Spain, Portugal
Bonus Onboard Spend
Exclusive Savings
Inside
$720
Oceanview
$1,057
Balcony
$1,564
Suite
$2,623
From (Per Person)
A$720
Save 11
Per Person
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise
 (1)

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Nov 2026 to Feb 2027
Visits: Spain, Portugal
Bonus Onboard Spend
Exclusive Savings
Inside
$1,839
Oceanview
$2,044
Balcony
$2,746
Suite
$8,634
From (Per Person)
A$1,839
Per Person
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise
 (1)

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Nov 2026 to Nov 2027
Visits: Spain, Portugal
Bonus Onboard Spend
Exclusive Savings
Inside
$749
Oceanview
$1,057
Balcony
$1,534
Suite
$2,522
From (Per Person)
A$749
Per Person
View Trip
6 Day A Journey From Atlantic Isles To Lisbon’s Maritime Grace with Explora Journeys
Cruise
 (1)

6 Days (5 Nights) Santa Cruz De Tenerife to Lisbon
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 16 December 2026
Visits: Spain, Portugal
Exclusive Savings
Suite
$4,185
From (Per Person)
A$4,185
Save 85
Per Person
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Santa Cruz De Tenerife to Santa Cruz De Tenerife
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 14 February 2027
Visits: Spain, Portugal
Exclusive Savings
Inside
$1,429
Oceanview
$1,706
Balcony
$1,726
Suite
$2,607
From (Per Person)
A$1,429
Per Person
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Santa Cruz De Tenerife to Santa Cruz De Tenerife
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Dec 2026 to Mar 2028
Visits: Spain, Portugal
Exclusive Savings
Inside
$1,241
Oceanview
$1,400
Balcony
$1,538
Suite
$2,251
From (Per Person)
A$1,241
Per Person
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise
 (1)

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Nov 2026 to Feb 2027
Visits: Spain, Portugal
Bonus Onboard Spend
Exclusive Savings
Inside
$1,939
Oceanview
$2,123
Balcony
$2,746
Suite
$7,822
From (Per Person)
A$1,939
Per Person
View Trip
9 Day Canary Islands with MSC Cruises
Cruise
 (2)

9 Days (8 Nights) Santa Cruz De Tenerife to Rome
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Apr 2027 to Mar 2028
Visits: Spain, Morocco, Italy
Exclusive Savings
Inside
$1,321
Oceanview
$1,588
Balcony
$1,638
Suite
$2,608
From (Per Person)
A$1,321
Per Person
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise
 (1)

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departures: Oct 2026 to Mar 2027
Visits: Spain, Portugal
Bonus Onboard Spend
Exclusive Savings
Inside
$1,987
Oceanview
$2,285
Balcony
$3,246
Suite
-
From (Per Person)
A$1,987
Per Person
View Trip
9 Day Rhythms of Spain: From the Canaries to Málaga with Ponant
Cruise

9 Days (8 Nights) Santa Cruz De Tenerife to Malaga
Cruise Line: Ponant
Ship: L'Austral
Departure: 08 April 2027
Visits: Spain, Portugal, Morocco
Exclusive Savings
Oceanview
$7,167
Balcony
$7,729
Suite
$12,540
From (Per Person)
A$7,167
Save 203
Per Person
View Trip
Results: 18 results

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