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Cruises from Rome to Barcelona

Are you looking for a cruise from Rome to Barcelona? September is the most popular month to cruise between Rome and Barcelona and there are 233 departures available from sixteen of the world's leading cruise lines.
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95 Cruises (233 Cruise Departures)
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+11 more), Viking Libra, Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Apr 2026 to Sep 2028
Visit: Italy, Monaco, France, Spain
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$2,599
Suite
$3,499
From
US$2,599
Save 650
Per Person
View Trip
8 Day Riviera Reverie with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 30 September 2027
Visit: Italy, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$9,275
Suite
$9,716
From
US$9,275
Save 9,623
Per Person
View Trip
10 Day Fountains To Flamenco with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sonata
Departure: 09 November 2027
Visit: Italy, Sardinia, Corsica, France, Spain
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,342
Suite
$6,428
From
US$4,342
Save 4,556
Per Person
View Trip
11 Day Old World Exploration with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 01 November 2026
Visit: Italy, Malta, Tunisia, Sicily, France, Spain
Exclusive Savings
Inside
-
Oceanview
$8,203
Balcony
$9,428
Suite
$10,996
From
US$8,203
Save 8,495
Per Person
View Trip
8 Day A Journey Of Shimmering Shores & Timeless Mediterranean Treasures with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departures: Jun 2026 to Sep 2026
Visit: Italy, Corsica, France, Spain
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$5,520
From
US$5,520
Per Person
View Trip
10 Day Western Mediterranean Cruise From Rome To Barcelona with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Prima
Departure: 28 April 2027
Visit: Italy, France, Sicily, Sardinia, Spain
Exclusive Savings
Inside
$1,878
Oceanview
$2,227
Balcony
$2,751
Suite
$3,595
From
US$1,878
Save 51
Per Person
View Trip
14 Day Civitavecchia to Barcelona with Silversea
Cruise

14 Days (13 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 12 July 2026
Visit: Italy, France, Monaco, Spain
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$6,800
Suite
$11,800
From
US$6,800
Per Person
View Trip
8 Day Italy, France & Spain Cruise: Rome, Florence & Barcelona with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 15 May 2027
Visit: Italy, Monaco, France, Spain
Azamara Always Included
Inside
$2,119
Oceanview
$2,383
Balcony
$3,150
Suite
$5,080
From
US$2,119
Per Person
View Trip
11 Day Italy, France & Spain Cruise: Florence, Marseille & Barcelona with Azamara Cruises
Cruise
 (8)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 17 July 2027
Visit: Italy, Monaco, France, Spain
Azamara Always Included
Exclusive Savings
Inside
$3,747
Oceanview
$3,630
Balcony
$4,756
Suite
$7,627
From
US$3,630
Save 89
Per Person
View Trip
8 Day Christmas Cruise: Florence, Mahon & Palma with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 22 December 2026
Visit: Italy, Spain
Azamara Always Included
Inside
$2,049
Oceanview
$2,039
Balcony
$2,326
Suite
$4,237
From
US$2,039
Per Person
View Trip
8 Day Italy, Spain & French Riviera with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departures: May 2027 to Sep 2027
Visit: Italy, France, Spain
Bonus Onboard Credit
Exclusive Savings
Inside
$1,075
Oceanview
$1,425
Balcony
$1,687
Suite
$2,212
From
US$1,075
Save 614
Per Person
View Trip
8 Day Essential Mediterranean with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 09 June 2026
Visit: Italy, Monaco, France, Spain
Your World Inclusions
Exclusive Savings
Inside
$1,725
Oceanview
$1,875
Balcony
$3,482
Suite
-
From
US$1,725
Save 2,873
Per Person
View Trip
8 Day Civitavecchia (Rome) to Barcelona with Silversea
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Nova
Departure: 07 November 2027
Visit: Italy, France, Spain
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$6,900
Suite
$10,100
From
US$6,900
Per Person
View Trip
15 Day Mediterranean with Greece, Turkey, & Adriatic with Princess
Cruise
 (6)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Sep 2026 to Oct 2026
Visit: Italy, Greece, Turkey, Montenegro, Sicily, Spain
Princess Standard
Inside
$1,947
Oceanview
$2,427
Balcony
$2,647
Suite
$3,488
From
US$1,947
Per Person
View Trip
11 Day Mediterranean Isles with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 November 2026
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Your World Inclusions
Exclusive Savings
Inside
$3,710
Oceanview
-
Balcony
$3,454
Suite
$4,643
From
US$3,454
Save 6,644
Per Person
View Trip
8 Day Italy, France & Spain Cruise: Rome, Nice & Barcelona with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 04 March 2028
Visit: Italy, France, Spain
Azamara Always Included
Inside
$1,599
Oceanview
$2,009
Balcony
$2,549
Suite
$3,839
From
US$1,599
Per Person
View Trip
10 Day Italian Riviera & France with Celebrity Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: May 2026 to Sep 2026
Visit: Italy, France, Spain
Exclusive Savings
Inside
$1,598
Oceanview
$1,999
Balcony
$2,127
Suite
$3,928
From
US$1,598
Save 1,263
Per Person
View Trip
8 Day Italy, Spain & French Riviera with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 27 July 2026
Visit: Italy, France, Spain
Exclusive Savings
Inside
$1,310
Oceanview
$1,602
Balcony
$1,876
Suite
$3,950
From
US$1,310
Save 838
Per Person
View Trip
8 Day Rome to Barcelona with Silversea
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Nova
Departure: 23 November 2026
Visit: Italy, Sicily, Tunisia, Sardinia, Spain
All-Inclusive Fare
Inside
-
Oceanview
-
Balcony
$6,200
Suite
$9,200
From
US$6,200
Per Person
View Trip
8 Day European Yearnings with Oceania Cruises
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 02 July 2027
Visit: Italy, Monaco, France, Spain
Your World Inclusions
Your World Included Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,175
Suite
$4,921
From
US$3,175
Save 3,323
Per Person
View Trip
12 Day Spanish Flavors & Rhythms with Regent Seven Seas
Cruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 11 October 2027
Visit: Italy, Monaco, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$11,290
Suite
$13,054
From
US$11,290
Save 11,708
Per Person
View Trip
8 Day A Journey Of Treasured Secrets & Chic Promenades with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 10 August 2026
Visit: Italy, Monaco, France, Spain
Sky & Sea
Inside
-
Oceanview
-
Balcony
-
Suite
$5,310
From
US$5,310
Per Person
View Trip
8 Day Mediterranean Cruise From Rome To Barcalona with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2027 to Aug 2027
Visit: Italy, Sicily, France, Spain
Inside
$1,069
Oceanview
$1,709
Balcony
$1,599
Suite
$1,779
From
US$1,069
Per Person
View Trip
8 Day Italy, Spain & French Riviera with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 15 June 2026
Visit: Italy, France, Spain
Exclusive Savings
Inside
$1,145
Oceanview
$1,294
Balcony
$1,507
Suite
$2,752
From
US$1,294
Save 648
Per Person
View Trip
8 Day Italy, Spain & French Riviera with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 07 September 2026
Visit: Italy, France, Spain
Exclusive Savings
Inside
$1,519
Oceanview
-
Balcony
$1,981
Suite
$2,616
From
US$1,519
Save 746
Per Person
View Trip
10 Day Pasta To Paella with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Allura
Departure: 15 April 2028
Visit: Italy, Sardinia, Monaco, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,613
Suite
$6,135
From
US$3,613
Save 3,785
Per Person
View Trip
11 Day Italy & Spain Cruise: Florence, Marseille & Barcelona with Azamara Cruises
Cruise
 (8)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 03 March 2027
Visit: Italy, France, Spain
Azamara Circle Member - Quarterly Saving
Azamara Always Included
Inside
$2,579
Oceanview
$2,898
Balcony
$3,295
Suite
$5,061
From
US$2,579
Per Person
View Trip
8 Day Coastal Kaleidoscope with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 26 September 2027
Visit: Italy, Monaco, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$1,899
Oceanview
$2,199
Balcony
$3,222
Suite
$4,677
From
US$1,899
Save 1,899
Per Person
View Trip
8 Day A Journey To Italian Hidden Gems & The Heartbeat Of Catalan Culture with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 13 May 2026
Visit: Italy, Sicily, Tunisia, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$5,520
From
US$5,520
Per Person
View Trip
8 Day A Journey through Italian Treasures & French Riviera Elegance with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departures: May 2027 to Sep 2027
Visit: Italy, Corsica, Monaco, France, Spain
Inside
-
Oceanview
-
Balcony
-
Suite
$4,450
From
US$4,450
Per Person
View Trip
Results: 1-30 of 95

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