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Cruises from Rome to Barcelona

Are you looking for a cruise from Rome to Barcelona? June, August and September are the most popular months to cruise between Rome and Barcelona and there are 181 departures available from fifteen of the world's leading cruise lines.
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87 Cruises (181 Cruise Departures)
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise
 (5)

8 Days (7 Nights) Rome to Barcelona
Operated By: Viking Cruises
Ships: Viking Jupiter, Viking Libra (+9 more), Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Aug 2025 to Sep 2027
Countries Visited: Italy, Monaco, France, Spain
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$2,799
SUITE
$3,799
Save (per person) 1,000
From (per person) 2,799
View Trip
6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 12 December 2025
Countries Visited: Italy, France, Spain
One Way Cruise Offer
INSIDE
$479
OCEANVIEW
$559
BALCONY
$679
SUITE
$1,099
From (per person) 479
View Trip
12 Day Grand Western Mediterranean with Princess
Cruise
 (3)

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departure: 29 July 2025
Countries Visited: Italy, Sicily, France, Spain (+1 more), Gibraltar
Exclusive Deal
INSIDE
$1,799
OCEANVIEW
-
BALCONY
-
SUITE
-
From (per person) 1,799
View Trip
10 Day Italian Riviera & France with Celebrity Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Jun 2026 to Aug 2026
Countries Visited: Italy, France, Spain
Exclusive Deal
INSIDE
$1,176
OCEANVIEW
$1,176
BALCONY
$1,471
SUITE
$4,673
Save (per person) 968
From (per person) 1,176
View Trip
15 Day Mediterranean with Greek Isles, Italy & Turkey with Princess
Cruise
 (3)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Sep 2026 to Oct 2026
Countries Visited: Italy, Greece, Turkey, Montenegro (+2 more), Sicily, Spain
Exclusive DealSummer Swing Sale
INSIDE
$2,302
OCEANVIEW
$3,042
BALCONY
$3,566
SUITE
$3,942
From (per person) 2,302
View Trip
13 Day Roman Holiday To Toulon & Beyond with Regent Seven Seas
Cruise

13 Days (12 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 14 November 2025
Countries Visited: Italy, France, Spain, Corsica (+1 more), Sardinia
Sale Into SummerEarly Booking Saving
INSIDE
-
OCEANVIEW
-
BALCONY
$8,700
SUITE
$9,140
Save (per person) 18,698
From (per person) 8,700
View Trip
8 Day Italy & France Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Voyager of the Seas
Departure: 20 October 2025
Countries Visited: Italy, Sicily, France, Spain
Latest Offer
INSIDE
$975
OCEANVIEW
$1,073
BALCONY
$1,414
SUITE
-
Save (per person) 492
From (per person) 975
View Trip
21 Day France & Spanish Treasures with Seabourn
Cruise

21 Days (20 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 21 June 2025
Countries Visited: Italy, Malta, Tunisia, France (+3 more), Spain, Gibraltar, Morocco
A Sail To Remember
INSIDE
-
OCEANVIEW
-
BALCONY
$9,679
SUITE
$34,900
From (per person) 9,679
View Trip
15 Day Mediterranean with Greece, Turkey, & Italy with Princess
Cruise
 (3)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Apr 2026 to Sep 2026
Countries Visited: Italy, Greece, Turkey, Montenegro (+2 more), Sicily, Spain
Exclusive DealSummer Swing Sale
INSIDE
$2,013
OCEANVIEW
$2,543
BALCONY
$2,933
SUITE
$3,443
From (per person) 2,013
View Trip
11 Day Rome to Barcelona with Silversea
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Muse
Departure: 31 July 2026
Countries Visited: Italy, Sicily, Malta, Tunisia (+2 more), Sardinia, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$8,200
BALCONY
$9,200
SUITE
$21,000
From (per person) 8,200
View Trip
8 Day A Journey Of Antique Treasures To Sumptuous Catalan with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 07 September 2026
Countries Visited: Italy, Monaco, France, Spain
Explora Early Booking Benefit
INSIDE
-
OCEANVIEW
-
BALCONY
$5,285
SUITE
$6,095
From (per person) 5,285
View Trip
4 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

4 Days (3 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Allure of the Seas
Departures: Oct 2025 to Oct 2026
Countries Visited: Italy, Spain
Latest Offer
INSIDE
$756
OCEANVIEW
$796
BALCONY
$918
SUITE
$1,494
Save (per person) 367
From (per person) 756
View Trip
12 Day Rivieras & Yacht Havens Voyage with Azamara Cruises
Cruise
 (3)

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 26 August 2025
Countries Visited: Italy, Monaco, France, Spain
Azamara Circle Loyalty Quarterly Savings
INSIDE
$2,399
OCEANVIEW
$2,589
BALCONY
$3,159
SUITE
$7,319
From (per person) 2,399
View Trip
21 Day An Extended Journey To Castaway Canaries, Cadiz And Casablanca with Explora Journeys
Cruise
 (1)

21 Days (20 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 13 October 2025
Countries Visited: Italy, Sicily, Malta, Tunisia (+4 more), Sardinia, Spain, Gibraltar, Morocco
Upgrade Your Ocean OfferBest Available Fare
INSIDE
-
OCEANVIEW
-
BALCONY
$11,920
SUITE
$19,045
From (per person) 11,920
View Trip
11 Day Mediterranean Melange with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 29 October 2025
Countries Visited: Italy, Sicily, Sardinia, Corsica (+3 more), Monaco, France, Spain
Fleetwide SaleExclusive Deal
INSIDE
$2,699
OCEANVIEW
$3,299
BALCONY
$5,349
SUITE
$6,699
Save (per person) 2,699
From (per person) 2,699
View Trip
8 Day Mediterranean Passage with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 02 December 2026
Countries Visited: Italy, Corsica, France, Spain
Exclusive Deal
INSIDE
$1,999
OCEANVIEW
$2,199
BALCONY
$3,199
SUITE
$4,499
Save (per person) 1,999
From (per person) 1,999
View Trip
8 Day Italy, Spain & French Riviera with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 27 July 2026
Countries Visited: Italy, France, Spain
Latest Offer
INSIDE
$1,435
OCEANVIEW
$1,442
BALCONY
$2,081
SUITE
$2,716
Save (per person) 673
From (per person) 1,435
View Trip
8 Day A Journey To Italian Hidden Gems & The Heartbeat Of Catalan Culture with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 13 May 2026
Countries Visited: Italy, Sicily, Tunisia, Spain
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$4,965
SUITE
$5,730
From (per person) 4,965
View Trip
8 Day Western Mediterranean Cruise: Italy, France & Spain with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 31 October 2026
Countries Visited: Italy, Monaco, France, Spain
INSIDE
$2,279
OCEANVIEW
$2,729
BALCONY
$3,039
SUITE
$4,199
From (per person) 2,279
View Trip
11 Day Grand Mediterranean with Princess
Cruise
 (3)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Majestic Princess
Departure: 30 June 2025
Countries Visited: Italy, Greece, Turkey, Sicily (+1 more), Spain
Exclusive Deal
INSIDE
$1,249
OCEANVIEW
-
BALCONY
$1,827
SUITE
$1,999
From (per person) 1,249
View Trip
11 Day Autumnal Mediterranean with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 18 October 2025
Countries Visited: Italy, Sicily, Malta, Tunisia (+3 more), Monaco, France, Spain
Fleetwide SaleExclusive Deal
INSIDE
$3,399
OCEANVIEW
$3,699
BALCONY
$5,199
SUITE
$7,199
Save (per person) 3,399
From (per person) 3,399
View Trip
8 Day A Journey Of Mediterranean Wonders From Ancient Secrets To Modren Buzzing Vibes with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 05 October 2026
Countries Visited: Italy, Monaco, France, Spain
Explora Early Booking BenefitBest Available Fare
INSIDE
-
OCEANVIEW
-
BALCONY
$4,380
SUITE
$5,055
From (per person) 4,380
View Trip
12 Day Rome to Barcelona with Silversea
Cruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 29 May 2026
Countries Visited: Italy, Corsica, Monaco, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$10,500
From (per person) 10,500
View Trip
10 Day A Journey to UNESCO Malta & Balearic Bliss with Explora Journeys
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 13 October 2025
Countries Visited: Italy, Sicily, Malta, Tunisia (+2 more), Sardinia, Spain
Upgrade Your Ocean OfferBest Available Fare
INSIDE
-
OCEANVIEW
-
BALCONY
$5,650
SUITE
$9,355
From (per person) 5,650
View Trip
10 Day Italy to France & Spain with Virgin Voyages
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 07 October 2025
Countries Visited: Italy, Sardinia, Corsica, France (+1 more), Spain
Sail Into Deeper Savings Best Rate
INSIDE
$1,566
OCEANVIEW
$1,783
BALCONY
$2,151
SUITE
$4,824
From (per person) 1,566
View Trip
15 Day Mediterranean with Greece, Turkey, & Italy with Princess
Cruise
 (3)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departure: 06 September 2025
Countries Visited: Italy, Greece, Turkey, Montenegro (+2 more), Sicily, Spain
Exclusive DealSummer Swing Sale
INSIDE
$3,211
OCEANVIEW
$3,561
BALCONY
-
SUITE
$5,191
From (per person) 3,211
View Trip
8 Day A Journey of Volcanic Vistas & Catalonian Culture with Explora Journeys
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 29 September 2025
Countries Visited: Italy, Sicily, Tunisia, Sardinia (+1 more), Spain
Upgrade Your Ocean OfferBest Available Fare
INSIDE
-
OCEANVIEW
-
BALCONY
$5,130
SUITE
$6,220
From (per person) 5,130
View Trip
11 Day Italy & Spain Cruise: Florence, Marseilles & Barcelona with Azamara Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 03 March 2027
Countries Visited: Italy, France, Spain
INSIDE
$2,889
OCEANVIEW
$3,319
BALCONY
$4,119
SUITE
$6,119
From (per person) 2,889
View Trip
8 Day Mediterranean Cruise: Itlay, France & Spain with Azamara Cruises
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 07 November 2026
Countries Visited: Italy, France, Spain
INSIDE
$2,079
OCEANVIEW
$2,409
BALCONY
$2,699
SUITE
$4,249
From (per person) 2,079
View Trip
8 Day Western Mediterranean: Italy, France & Gibraltar with Holland America
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departure: 29 August 2026
Countries Visited: Italy, Corsica, France, Gibraltar (+1 more), Spain
Exclusive Deal
INSIDE
$1,109
OCEANVIEW
$1,189
BALCONY
$1,619
SUITE
$2,489
From (per person) 1,109
View Trip
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