Home > Cruises > Europe Cruises > Mediterranean Cruises > Cruises from Rome to Barcelona

Cruises from Rome to Barcelona

Are you looking for a cruise from Rome to Barcelona? September is the most popular month to cruise between Rome and Barcelona and there are 250 departures available from fifteen of the world's leading cruise lines.
Filter Results
Departures
Show More...
Duration
4 Days
32 Days
Regions
Ship Size
Ship Features
Operators
Show More...
Price
$500pp
$33,050pp
Countries
Show More...
Filter Results
116 Cruises (250 Cruise Departures)
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+11 more), Viking Libra, Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Sep 2026 to Sep 2028
Visit: Italy, Monaco, France, Spain
Viking Savings Event
Bonus Shipboard Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,964
Suite
$6,414
From
A$3,964
Save 1,403
Per Person
View Trip
11 Day Italy & Spain Cruise: Florence, Marseille & Barcelona with Azamara Cruises
Cruise
 (8)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 03 March 2027
Visit: Italy, France, Spain
Azamara Circle Member - Quarterly Saving
Azamara Always Included
Exclusive Savings
Inside
$3,366
Oceanview
$4,425
Balcony
$4,317
Suite
$6,287
From
A$3,366
Per Person
View Trip
8 Day Western Mediterranean Cruise: Italy, France & Spain with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 31 October 2026
Visit: Italy, Monaco, France, Spain
Azamara Always Included
Exclusive Savings
Inside
$3,051
Oceanview
$3,678
Balcony
$4,129
Suite
$5,961
From
A$3,051
Save 48
Per Person
View Trip
22 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 14 July 2028
Visit: Italy, Spain, France, Corsica (+5 more), Malta, Montenegro, Croatia, Greece, Sicily
Exclusive Savings
Inside
$6,243
Oceanview
$6,936
Balcony
$7,926
Suite
$14,658
From
A$6,243
Per Person
View Trip
8 Day Mediterranean Cruise From Rome To Barcalona with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2027
Visit: Italy, Sicily, France, Spain
Just Cruise Fare
Exclusive Savings
Inside
$2,032
Oceanview
$2,613
Balcony
$2,688
Suite
$2,955
From
A$2,032
Per Person
View Trip
15 Day Mediterranean with Greece, Turkey, & Adriatic with Princess
Cruise
 (7)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Mar 2028 to Sep 2028
Visit: Italy, Sicily, Greece, Turkey, Montenegro, Spain
Princess Standard
Sanctuary Collection
Exclusive Savings
Inside
$2,676
Oceanview
$3,240
Balcony
$4,384
Suite
$4,953
From
A$2,676
Per Person
View Trip
8 Day Regards From The Riviera with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 09 September 2027
Visit: Italy, France, Spain
Your World Inclusions
Exclusive Savings
Inside
$2,896
Oceanview
$3,100
Balcony
$4,807
Suite
$6,514
From
A$2,896
Save 2,054
Per Person
View Trip
9 Day A Journey From Roman Shores To Contemporary Catalan Flair with Explora Journeys
Cruise
 (1)

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jun 2028 to Sep 2028
Visit: Italy, Corsica, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$7,120
From
A$7,120
Save 156
Per Person
View Trip
15 Day Spain, Italy And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 28 May 2027
Visit: Italy, Malta, Montenegro, Croatia, Sicily, Spain
First Come, First Served Offer
Exclusive Savings
Inside
$4,330
Oceanview
$4,895
Balcony
$5,300
Suite
$10,349
From
A$4,330
Per Person
View Trip
29 Day Mediterranean, Adriatic, Greece And Turkiye with Cunard
Cruise
 (13)

29 Days (28 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 26 May 2028
Visit: Italy, Sicily, Greece, Turkey (+4 more), Malta, Montenegro, Croatia, Spain
Exclusive Savings
Inside
$8,523
Oceanview
$9,612
Balcony
$10,701
Suite
$21,591
From
A$8,523
Per Person
View Trip
11 Day A Journey From Amalfi’s Cliffs To Andalusian Sun with Explora Journeys
Cruise
 (1)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 14 January 2027
Visit: Italy, Sardinia, Spain, Morocco
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$8,379
From
A$8,379
Save 171
Per Person
View Trip
8 Day Italy, Spain & French Riviera with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 07 September 2026
Visit: Italy, France, Spain
Exclusive Savings
Inside
$2,123
Oceanview
$2,497
Balcony
$2,264
Suite
$5,729
From
A$2,123
Save 1,126
Per Person
View Trip
15 Day Mediterranean with Greece, Turkey, & Adriatic with Princess
Cruise
 (7)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: May 2027 to Aug 2027
Visit: Italy, Greece, Turkey, Montenegro, Sicily, Spain
Princess Standard
Sanctuary Collection
Exclusive Savings
Inside
$2,859
Oceanview
$3,354
Balcony
$4,146
Suite
$4,858
From
A$2,859
Per Person
View Trip
10 Day A Journey To Spain's Icons & North Africa's Sunlit Shores with Explora Journeys
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 02 February 2027
Visit: Italy, Sicily, Tunisia, Algeria, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$7,531
From
A$7,531
Save 154
Per Person
View Trip
8 Day Mediterranean Cruise From Rome To Barcalona with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: Jun 2027 to Aug 2027
Visit: Italy, Sicily, France, Spain
Just Cruise Fare
Exclusive Savings
Inside
$2,107
Oceanview
-
Balcony
$2,836
Suite
$3,104
From
A$2,107
Per Person
View Trip
32 Day The Best of the Mediterranean with Princess
Cruise
 (2)

32 Days (31 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Enchanted Princess
Departure: 05 August 2028
Visit: Italy, Corsica, Malta, Montenegro (+5 more), Croatia, Greece, Cyprus, Turkey, Spain
Princess Standard
Exclusive Savings
Inside
$5,978
Oceanview
-
Balcony
$6,764
Suite
$9,072
From
A$5,978
Per Person
View Trip
8 Day Mediterranean Passage with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 02 December 2026
Visit: Italy, Corsica, France, Spain
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
$2,904
Balcony
$2,568
Suite
$3,390
From
A$2,568
Save 4,182
Per Person
View Trip
10 Day Italian Riviera, France & Spain with Celebrity Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: May 2027 to Oct 2027
Visit: Italy, France, Spain
Exclusive Savings
Inside
$1,912
Oceanview
$2,518
Balcony
$2,735
Suite
$6,023
From
A$1,912
Save 1,676
Per Person
View Trip
8 Day Italy, Spain & French Riviera with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 27 July 2026
Visit: Italy, France, Spain
Exclusive Savings
Inside
$2,146
Oceanview
$2,301
Balcony
$2,503
Suite
$6,442
From
A$2,146
Save 1,139
Per Person
View Trip
8 Day Western Mediterranean with Cunard
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 10 August 2026
Visit: Italy, Spain, France
Exclusive Savings
Inside
-
Oceanview
$1,882
Balcony
$2,625
Suite
$4,654
From
A$1,882
Per Person
View Trip
15 Day Italy, France And Spain with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 13 July 2026
Visit: Italy, France, Corsica, Spain
Exclusive Savings
Inside
$3,429
Oceanview
$3,786
Balcony
$4,459
Suite
$8,775
From
A$3,429
Per Person
View Trip
8 Day A Journey Of Mediterranean Colour, Cuisine & Remarkable Landmarks with Explora Journeys
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 09 October 2028
Visit: Italy, Corsica, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$6,595
From
A$6,595
Save 135
Per Person
View Trip
10 Day Italian Riviera & France with Celebrity Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Jun 2026 to Aug 2026
Visit: Italy, France, Spain
Exclusive Savings
Inside
$1,583
Oceanview
$1,778
Balcony
$2,072
Suite
$7,301
From
A$1,583
Save 1,357
Per Person
View Trip
10 Day Italian Riviera, France & Spain with Celebrity Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 08 June 2027
Visit: Italy, France, Spain
Exclusive Savings
Inside
$2,148
Oceanview
$2,908
Balcony
$3,393
Suite
$8,627
From
A$2,148
Save 1,477
Per Person
View Trip
8 Day Mediterranean Cruise From Rome To Barcalona with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: Jun 2026 to Oct 2027
Visit: Italy, Sicily, France, Spain
Just Cruise Fare
Exclusive Savings
Inside
$1,362
Oceanview
$1,660
Balcony
$1,958
Suite
$2,151
From
A$1,362
Per Person
View Trip
8 Day Italy And France with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 24 September 2027
Visit: Italy, France, Corsica, Spain
Exclusive Savings
Inside
$2,031
Oceanview
$2,278
Balcony
$2,526
Suite
$4,951
From
A$2,031
Per Person
View Trip
8 Day Christmas Cruise: Florence, Mahon & Palma with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 22 December 2026
Visit: Italy, Spain
Azamara Always Included
Exclusive Savings
Inside
$2,672
Oceanview
$3,103
Balcony
$3,514
Suite
$5,778
From
A$2,672
Per Person
View Trip
11 Day Italy, France & Spain Cruise: Florence, Marseille & Barcelona with Azamara Cruises
Cruise
 (8)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 17 July 2027
Visit: Italy, Monaco, France, Spain
Azamara Always Included
Exclusive Savings
Inside
$4,626
Oceanview
$4,479
Balcony
$5,861
Suite
$9,370
From
A$4,479
Save 70
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departures: Aug 2027 to Sep 2027
Visit: Italy, Corsica, Spain
Exclusive Savings
Inside
$2,278
Oceanview
$2,476
Balcony
$2,872
Suite
$5,545
From
A$2,278
Per Person
View Trip
8 Day Italy, France & Spain Cruise: Rome, Florence & Barcelona with Azamara Cruises
Cruise
 (4)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 15 May 2027
Visit: Italy, Monaco, France, Spain
Azamara Always Included
Exclusive Savings
Inside
$3,024
Oceanview
$3,485
Balcony
$4,612
Suite
$7,454
From
A$3,024
Per Person
View Trip
Results: 1-30 of 116

No trips found. Try adjusting the search filters.




Cruises found! Scroll up to view.

Europe Cruises

All Europe Cruises Adriatic Cruises Aegean Cruises Baltic Cruises Croatia Cruises Med Cruises Greek Islands Cruises UK Cruises Western Europe Cruises

Travel Styles

Festivals & Events Luxury Cruises Short Cruise Breaks

Countries

Albania Corsica Croatia Cyprus Egypt England France Gibraltar Italy Malta Mexico Monaco Montenegro Morocco Portugal Sardinia Sicily Slovenia Spain Tunisia Turkey USA

Cities

Cruises from Rome

Routes

Cruises from Bologna to Barcelona Cruises from Rome to Barcelona Cruises from Trieste to Barcelona Cruises from Venice to Barcelona

Country Routes

Cruises from Italy to Spain

Cruise Lines Exploring The Med

APT Med Cruises Azamara Med Cruises Celebrity Med Cruises Cunard Med Cruises Emerald Med Cruises G Adventures Med Cruises Intrepid Med Cruises MSC Med Cruises NCL Med Cruises Oceania Med Cruises P&O (UK) Med Cruises Ponant Med Cruises Princess Med Cruises Regent Seven Seas Med Cruises Royal Caribbean Med Cruises Scenic Med Cruises Silversea Med Cruises Viking Med Cruises Virgin Voyages Med Cruises

© 2010-2026. Global Journeys. You're viewing our site in Australian dollars.

    

Global Journeys | Terms & Conditions

Global Journeys Pty Ltd. Accredited Member of The Australian Travel Industry Association (ATIA). No. A11351.

Travel Industry Associations