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Cruises from Rome to Barcelona

Are you looking for a cruise from Rome to Barcelona? September is the most popular month to cruise between Rome and Barcelona and there are 241 departures available from fifteen of the world's leading cruise lines.
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109 Cruises (241 Cruise Departures)
8 Day Mediterranean Cruise From Rome To Barcalona with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: Jun 2026 to Oct 2027
Visit: Italy, Sicily, France, Spain
Inside
$579
Oceanview
$869
Balcony
$959
Suite
$1,109
From
US$579
Per Person
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Astrea, Viking Jupiter (+11 more), Viking Libra, Viking Lyra, Viking Mars, Viking Mira, Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Vesta
Departures: Jun 2026 to Sep 2028
Visit: Italy, Monaco, France, Spain
Multiple Deals Available
Inside
-
Oceanview
-
Balcony
$2,699
Suite
$3,499
From
US$2,699
Save 800
Per Person
View Trip
8 Day Mediterranean Cruise From Rome To Barcalona with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: Jun 2027 to Aug 2027
Visit: Italy, Sicily, France, Spain
Inside
$1,209
Oceanview
$1,629
Balcony
$1,699
Suite
$1,919
From
US$1,209
Per Person
View Trip
15 Day Italy, France And Spain with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 13 July 2026
Visit: Italy, France, Corsica, Spain
Inside
$1,809
Oceanview
$1,949
Balcony
$2,179
Suite
$4,749
From
US$1,809
Per Person
View Trip
21 Day An Extended Journey Between Continents & Coastlines with Explora Journeys
Cruise
 (1)

21 Days (20 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 04 January 2027
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain, Morocco
Inside
-
Oceanview
-
Balcony
-
Suite
$9,490
From
US$9,490
Per Person
View Trip
10 Day Italian Riviera, France & Spain with Celebrity Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: May 2027 to Oct 2027
Visit: Italy, France, Spain
Exclusive Savings
Inside
$1,839
Oceanview
$2,101
Balcony
$1,890
Suite
$4,299
From
US$1,839
Save 1,412
Per Person
View Trip
22 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 14 July 2028
Visit: Italy, Spain, France, Corsica (+5 more), Malta, Montenegro, Croatia, Greece, Sicily
Cunard Fare
Value Fare
Inside
$4,364
Oceanview
$4,859
Balcony
$5,939
Suite
$10,169
From
US$4,364
Per Person
View Trip
8 Day Rome To Romance with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 10 April 2028
Visit: Italy, Corsica, Monaco, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,199
Oceanview
$2,849
Balcony
$3,499
Suite
$4,799
From
US$2,199
Save 2,199
Per Person
View Trip
10 Day Italian Riviera & France with Celebrity Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Jun 2026 to Aug 2026
Visit: Italy, France, Spain
Exclusive Savings
Inside
$1,199
Oceanview
$1,207
Balcony
$1,430
Suite
$4,224
From
US$1,199
Save 777
Per Person
View Trip
11 Day Italy, France & Spain Cruise: Florence, Marseille & Barcelona with Azamara Cruises
Cruise
 (8)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 17 July 2027
Visit: Italy, Monaco, France, Spain
Azamara Always Included
Inside
$3,839
Oceanview
$3,719
Balcony
$4,879
Suite
$7,839
From
US$3,719
Per Person
View Trip
11 Day A Journey From Amalfi’s Cliffs To Andalusian Sun with Explora Journeys
Cruise
 (1)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 14 January 2027
Visit: Italy, Sardinia, Spain, Morocco
Inside
-
Oceanview
-
Balcony
-
Suite
$5,005
From
US$5,005
Per Person
View Trip
15 Day Mediterranean with Greece, Turkey, & Adriatic with Princess
Cruise
 (7)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Sep 2026 to Oct 2026
Visit: Italy, Greece, Turkey, Montenegro, Sicily, Spain
Princess Standard
Sanctuary Collection
Inside
$1,747
Oceanview
$2,197
Balcony
$2,570
Suite
$3,447
From
US$1,747
Per Person
View Trip
8 Day Regards From The Riviera with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 09 September 2027
Visit: Italy, France, Spain
Your World Included Credit
Your World Inclusions
Exclusive Savings
Inside
$2,099
Oceanview
$2,249
Balcony
$3,499
Suite
$4,749
From
US$2,099
Save 2,099
Per Person
View Trip
10 Day Italian Riviera, France & Spain with Celebrity Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 08 June 2027
Visit: Italy, France, Spain
Exclusive Savings
Inside
$1,763
Oceanview
$3,151
Balcony
$3,021
Suite
$6,363
From
US$1,763
Save 1,029
Per Person
View Trip
15 Day Spain, Italy And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 28 May 2027
Visit: Italy, Malta, Montenegro, Croatia, Sicily, Spain
Bonus Onboard Credit
Value Fare
Inside
$2,439
Oceanview
$2,679
Balcony
$3,129
Suite
$6,409
From
US$2,439
Per Person
View Trip
8 Day Mediterranean Cruise From Rome To Barcalona with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2027 to May 2027
Visit: Italy, Sicily, France, Spain
Inside
$1,159
Oceanview
$1,549
Balcony
$1,599
Suite
$1,779
From
US$1,159
Per Person
View Trip
10 Day Italian Riviera, France & Spain with Celebrity Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 06 July 2027
Visit: Italy, France, Spain
Exclusive Savings
Inside
$2,002
Oceanview
$2,280
Balcony
$2,513
Suite
$5,599
From
US$2,002
Save 1,180
Per Person
View Trip
15 Day Mediterranean And Croatia with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 22 September 2028
Visit: Italy, Malta, Croatia, Greece, Sicily, Spain
Cunard Fare
Value Fare
Inside
$2,979
Oceanview
$3,339
Balcony
$4,149
Suite
$7,479
From
US$2,979
Per Person
View Trip
29 Day Mediterranean, Adriatic, Greece And Turkiye with Cunard
Cruise
 (13)

29 Days (28 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 26 May 2028
Visit: Italy, Sicily, Greece, Turkey (+4 more), Malta, Montenegro, Croatia, Spain
Cunard Fare
Value Fare
Inside
$5,929
Oceanview
$6,649
Balcony
$7,729
Suite
$14,659
From
US$5,929
Per Person
View Trip
8 Day Italy, Spain & French Riviera with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 27 July 2026
Visit: Italy, France, Spain
Exclusive Savings
Inside
$1,475
Oceanview
$1,642
Balcony
$1,773
Suite
$4,063
From
US$1,475
Save 765
Per Person
View Trip
10 Day Italian Riviera & France with Celebrity Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Jun 2026 to Sep 2026
Visit: Italy, France, Spain
Exclusive Savings
Inside
$1,648
Oceanview
$2,148
Balcony
$3,256
Suite
$6,724
From
US$1,648
Save 1,118
Per Person
View Trip
8 Day Rome to Barcelona with Silversea
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Nova
Departure: 23 November 2026
Visit: Italy, Sicily, Tunisia, Sardinia, Spain
All-Inclusive Plus Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,400
Suite
$7,400
From
US$4,400
Save 4,000
Per Person
View Trip
15 Day Italy, Spain And Adriatic with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 24 August 2026
Visit: Italy, Greece, Montenegro, Croatia, Malta, Spain
Inside
$2,499
Oceanview
$2,649
Balcony
$3,489
Suite
$5,219
From
US$2,499
Per Person
View Trip
15 Day Mediterranean with Greece, Turkey, & Adriatic with Princess
Cruise
 (7)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Jun 2026 to Oct 2027
Visit: Italy, Greece, Turkey, Montenegro, Sicily, Spain
Princess Standard
Sanctuary Collection
Inside
$1,814
Oceanview
$2,399
Balcony
$2,757
Suite
$3,080
From
US$1,814
Per Person
View Trip
8 Day Italy, France & Spain Cruise: Florence, Nice & Barcelona with Azamara Cruises
Cruise
 (8)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 27 May 2027
Visit: Italy, France, Spain
Azamara Always Included
Inside
$2,099
Oceanview
$2,399
Balcony
$3,159
Suite
$5,049
From
US$2,099
Per Person
View Trip
8 Day Western Mediterranean: Italy, France & Gibraltar with Holland America
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departures: Aug 2026 to Jul 2027
Visit: Italy, Corsica, France, Gibraltar, Spain
Fare Saver
Book Early & Have It All Fare Option
Inside
$1,299
Oceanview
$824
Balcony
$1,024
Suite
$1,674
From
US$824
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 20 July 2026
Visit: Italy, France, Corsica, Spain
Inside
$699
Oceanview
$799
Balcony
$999
Suite
$2,199
From
US$699
Per Person
View Trip
8 Day Italy, France & Spain Cruise: Rome, Florence & Barcelona with Azamara Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 15 May 2027
Visit: Italy, Monaco, France, Spain
Azamara Always Included
Inside
$1,919
Oceanview
$2,209
Balcony
$2,919
Suite
$4,709
From
US$1,919
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (13)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departures: Aug 2027 to Sep 2027
Visit: Italy, Corsica, Spain
Bonus Onboard Credit
Value Fare
Inside
$1,069
Oceanview
$1,159
Balcony
$1,309
Suite
$2,899
From
US$1,069
Per Person
View Trip
15 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departures: Jun 2028 to Aug 2028
Visit: Italy, Malta, Montenegro, Croatia, Greece, Sicily, Spain
Cunard Fare
Value Fare
Inside
$2,979
Oceanview
$3,384
Balcony
$4,149
Suite
$7,659
From
US$2,979
Per Person
View Trip
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