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Cruises from Rome to Barcelona

Are you looking for a cruise from Rome to Barcelona? September is the most popular month to cruise between Rome and Barcelona and there are 146 departures available from fourteen of the world's leading cruise lines.
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86 Cruises (146 Cruise Departures)
15 Day Italy, Spain And Adriatic with Cunard
Cruise

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 24 August 2026
Countries Visited: Italy, Greece, Montenegro, Croatia (+2 more), Malta, Spain
INSIDE
$3,320
OCEANVIEW
$3,667
BALCONY
$4,162
SUITE
$8,914
From 3,320
View Trip
8 Day Italy, France And Spain with Cunard
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 08 July 2024
Countries Visited: Italy, France, Spain
INSIDE
$1,595
OCEANVIEW
$1,704
BALCONY
$2,001
SUITE
$4,120
From 1,595
View Trip
8 Day A Journey From Rome To Tarragona with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 16 September 2024
Countries Visited: Spain, Malta, Sicily, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$7,618
SUITE
$9,261
From 9,499
View Trip
8 Day Western Mediterranean with Cunard
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 01 September 2025
Countries Visited: Italy, France, Spain
INSIDE
$1,427
OCEANVIEW
$1,645
BALCONY
$1,873
SUITE
$3,833
From 1,427
View Trip
8 Day A Journey From Civitavecchia To Barcelona with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 29 September 2025
Countries Visited: Italy, Sicily, Tunisia, Sardinia (+1 more), Spain
Exclusive DealThe Total Luxury Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$5,846
SUITE
$7,108
From 7,276
View Trip
8 Day Mediterranean Tapestry with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 15 November 2024
Countries Visited: Italy, France, Spain
Mutiple Deals Available
INSIDE
-
OCEANVIEW
$3,830
BALCONY
$3,993
SUITE
$4,953
Save 7,440
From 3,830
View Trip
9 Day Civitavecchia to Barcelona with Silversea
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 23 September 2025
Countries Visited: Italy, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$12,078
From 12,078
View Trip
8 Day A Journey Of Limoncello Days And Catalonia Nights with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 02 September 2024
Countries Visited: Italy, Sicily, Tunisia, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$7,618
SUITE
$9,261
From 11,425
View Trip
12 Day Rome to Barcelona with Silversea
Cruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 07 May 2025
Countries Visited: Italy, Monaco, France, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$14,256
From 14,256
View Trip
13 Day Greek Isles, Italy & Turkey with Celebrity Cruises
Cruise

13 Days (12 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 23 September 2024
Countries Visited: Italy, Greece, Turkey, Malta (+1 more), Spain
Exclusive Offer
INSIDE
$3,694
OCEANVIEW
-
BALCONY
-
SUITE
$11,659
Save 4,282
From 3,694
View Trip
10 Day Wonders Of Spain with Regent Seven Seas
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 09 May 2025
Countries Visited: Italy, France, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$12,277
SUITE
$13,465
Save 5,263
From 12,277
View Trip
21 Day France & Spanish Treasures with Seabourn
Cruise

21 Days (20 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departures: Jul 2024 to Jun 2025
Countries Visited: Italy, Malta, Tunisia, France (+3 more), Spain, Gibraltar, Morocco
Earlybird SavingExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$17,838
SUITE
$32,985
From 17,838
View Trip
8 Day A Journey Of Storied Italian Islands and Starry Spanish Nights with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 19 August 2024
Countries Visited: Italy, Sicily, Sardinia, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$7,618
SUITE
$9,261
From 13,306
View Trip
8 Day Italy, France And Spain with Cunard
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 11 August 2025
Countries Visited: Italy, France, Corsica, Spain
INSIDE
$1,427
OCEANVIEW
$1,645
BALCONY
$1,873
SUITE
$3,833
From 1,427
View Trip
29 Day Istanbul, Greek Islands And Mediterranean with Cunard
Cruise

29 Days (28 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 15 September 2025
Countries Visited: Italy, Greece, Montenegro, Croatia (+3 more), Malta, Spain, Turkey
INSIDE
$5,741
OCEANVIEW
$6,305
BALCONY
$7,058
SUITE
$15,334
From 5,741
View Trip
11 Day Riviera & Mediterranean Jewels with Seabourn
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departure: 10 August 2025
Countries Visited: Italy, Malta, Tunisia, France (+1 more), Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$9,909
SUITE
$18,522
From 9,909
View Trip
15 Day Charming Coasts & Treasures with Regent Seven Seas
Cruise

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 25 October 2025
Countries Visited: Italy, Sicily, Malta, Tunisia (+3 more), Corsica, Monaco, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$17,161
SUITE
$19,002
Save 6,959
From 17,161
View Trip
7 Day A Journey From Italian Piazzas To Tunisian Souks with Explora Journeys
Cruise

7 Days (6 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 30 September 2024
Countries Visited: Italy, Sicily, Tunisia, Spain (+3 more), Gibraltar, Portugal, Morocco
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$6,866
SUITE
$7,945
From 10,296
View Trip
11 Day Greek Isles & Turkey with Celebrity Cruises
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 17 August 2024
Countries Visited: Italy, Greece, Turkey, Sicily (+1 more), Spain
Exclusive Offer
INSIDE
$2,318
OCEANVIEW
$2,488
BALCONY
$3,236
SUITE
$7,199
Save 3,116
From 2,318
View Trip
9 Day Rome to Barcelona with Silversea
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 10 November 2025
Countries Visited: Italy, France, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$8,118
BALCONY
$9,306
SUITE
$9,009
From 8,118
View Trip
15 Day Mediterranean with Greek Isles, Italy & Turkey with Princess
Cruise

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Apr 2025 to Aug 2025
Countries Visited: Italy, Greece, Turkey, Montenegro (+2 more), Sicily, Spain
INSIDE
$3,648
OCEANVIEW
$4,628
BALCONY
$5,202
SUITE
$6,282
From 3,648
View Trip
8 Day A Journey From Civitavecchia To Barcelona with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jun 2025 to Sep 2025
Countries Visited: Italy, Sicily, Tunisia, Sardinia (+1 more), Spain
Exclusive DealThe Total Luxury Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$5,197
SUITE
$6,341
From 7,796
View Trip
15 Day Mediterranean with Greek Isles, Italy & Turkey with Princess
Cruise

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Jun 2024 to Jul 2024
Countries Visited: Italy, Greece, Turkey, Montenegro (+2 more), Sicily, Spain
INSIDE
$5,447
OCEANVIEW
$5,902
BALCONY
$7,358
SUITE
$8,768
From 5,447
View Trip
8 Day A Journey From Civitavecchia To Barcelona with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Aug 2025 to Sep 2025
Countries Visited: Italy, Sicily, Sardinia, Spain
Exclusive DealThe Total Luxury Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$5,846
SUITE
$7,108
From 8,747
View Trip
8 Day Azure Summer with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 31 May 2025
Countries Visited: Italy, France, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$9,034
SUITE
$9,766
Save 5,826
From 9,034
View Trip
15 Day Spain, Italy And Adriatic with Cunard
Cruise

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 01 June 2026
Countries Visited: Italy, Greece, Montenegro, Croatia (+2 more), Malta, Spain
INSIDE
$3,172
OCEANVIEW
$3,518
BALCONY
$3,964
SUITE
$8,518
From 3,172
View Trip
10 Day Italian Riviera & France Cruise with Celebrity Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 05 August 2025
Countries Visited: Italy, France, Spain
Exclusive Offer
INSIDE
$2,766
OCEANVIEW
$3,225
BALCONY
$3,301
SUITE
$8,496
Save 3,546
From 2,766
View Trip
10 Day Italian Riviera & France Cruise with Celebrity Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Jun 2025 to Sep 2025
Countries Visited: Italy, France, Spain
Exclusive Offer
INSIDE
$2,461
OCEANVIEW
$2,920
BALCONY
$3,226
SUITE
$8,190
Save 3,479
From 2,461
View Trip
8 Day Italy, France, & Spain Cruise with Celebrity Cruises
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 10 August 2024
Countries Visited: Italy, Corsica, France, Spain
Exclusive Offer
INSIDE
$1,965
OCEANVIEW
$2,201
BALCONY
$2,690
SUITE
$5,497
Save 2,418
From 1,965
View Trip
11 Day Mediterranean Overture with Seabourn
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departure: 30 October 2024
Countries Visited: Italy, Sardinia, Corsica, Monaco (+2 more), France, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,701
SUITE
$16,740
From 10,701
View Trip
Results: 31-60 of 86

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