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Cruises from Rome to Barcelona

Are you looking for a cruise from Rome to Barcelona? September is the most popular month to cruise between Rome and Barcelona and there are 251 departures available from fifteen of the world's leading cruise lines.
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117 Cruises (251 Cruise Departures)
8 Day Rome To Romance with Oceania Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 10 April 2028
Visit: Italy, Corsica, Monaco, France, Spain
Your World Inclusions
Exclusive Savings
Inside
$3,340
Oceanview
$4,320
Balcony
$5,300
Suite
$7,259
From
A$3,340
Save 2,070
Per Person
View Trip
9 Day A Journey Of Italian Grandeur, Riviera Glamour & Catalan Style with Explora Journeys
Cruise
 (1)

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jul 2028 to Sep 2028
Visit: Italy, France, Corsica, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$7,120
From
A$7,120
Save 156
Per Person
View Trip
8 Day Mediterranean Cruise From Rome To Barcalona with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: Jun 2026 to Oct 2027
Visit: Italy, Sicily, France, Spain
Just Cruise Fare
Exclusive Savings
Inside
$1,362
Oceanview
$1,660
Balcony
$1,958
Suite
$2,151
From
A$1,362
Per Person
View Trip
8 Day Italy, France And Spain with Cunard
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 20 July 2026
Visit: Italy, France, Corsica, Spain
Exclusive Savings
Inside
$1,813
Oceanview
$1,813
Balcony
$2,229
Suite
$4,367
From
A$1,813
Per Person
View Trip
8 Day Civitavecchia (Rome) to Barcelona with Silversea
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Nova
Departure: 07 November 2027
Visit: Italy, France, Spain
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,468
Suite
$11,858
From
A$5,468
Save 3,832
Per Person
View Trip
11 Day A Journey From Amalfi’s Cliffs To Andalusian Sun with Explora Journeys
Cruise
 (1)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 14 January 2027
Visit: Italy, Sardinia, Spain, Morocco
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$8,379
From
A$8,379
Save 171
Per Person
View Trip
15 Day Mediterranean with Greece, Turkey, & Adriatic with Princess
Cruise
 (7)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: May 2027 to Aug 2027
Visit: Italy, Greece, Turkey, Montenegro, Sicily, Spain
Princess Standard
Sanctuary Collection
Exclusive Savings
Inside
$2,859
Oceanview
$3,354
Balcony
$4,146
Suite
$4,858
From
A$2,859
Per Person
View Trip
5 Day A Journey From Italy’s Cultural Heart To The Western Mediterranean with Explora Journeys
Cruise
 (1)

5 Days (4 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 05 December 2026
Visit: Italy, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$3,361
From
A$3,361
Save 69
Per Person
View Trip
8 Day Rome to Barcelona with Silversea
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Nova
Departure: 23 November 2026
Visit: Italy, Sicily, Tunisia, Sardinia, Spain
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,115
Suite
$11,662
From
A$6,115
Save 4,285
Per Person
View Trip
8 Day Italy, Spain & French Riviera with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 15 June 2026
Visit: Italy, France, Spain
Exclusive Savings
Inside
$2,086
Oceanview
-
Balcony
$4,364
Suite
-
From
A$2,993
Save 198
Per Person
View Trip
11 Day Mediterranean Isles with Oceania Cruises
Cruise
 (3)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 15 November 2026
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,252
Suite
$5,777
From
A$4,252
Save 4,988
Per Person
View Trip
8 Day Mediterranean Cruise From Rome To Barcalona with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: Jun 2027 to Aug 2027
Visit: Italy, Sicily, France, Spain
Just Cruise Fare
Exclusive Savings
Inside
$2,107
Oceanview
-
Balcony
$2,836
Suite
$3,104
From
A$2,107
Per Person
View Trip
22 Day Mediterranean, Adriatic And Greece with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 30 July 2027
Visit: Italy, Malta, Croatia, Greece, Sicily, Corsica, Spain
First Come, First Served Offer
Exclusive Savings
Inside
$5,768
Oceanview
$6,402
Balcony
$7,134
Suite
$16,460
From
A$5,768
Per Person
View Trip
15 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 01 September 2028
Visit: Italy, Malta, Croatia, Greece, Sicily, Spain
Exclusive Savings
Inside
$4,459
Oceanview
$5,152
Balcony
$5,993
Suite
$11,191
From
A$4,459
Per Person
View Trip
8 Day Italy, France & Spain Cruise: Rome, Florence & Barcelona with Azamara Cruises
Cruise
 (4)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 15 May 2027
Visit: Italy, Monaco, France, Spain
Azamara Always Included
Exclusive Savings
Inside
$3,024
Oceanview
$3,485
Balcony
$4,612
Suite
$7,454
From
A$3,024
Per Person
View Trip
8 Day Italy, Spain & French Riviera with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 07 September 2026
Visit: Italy, France, Spain
Exclusive Savings
Inside
$2,123
Oceanview
$2,497
Balcony
$2,264
Suite
$5,729
From
A$2,123
Save 1,126
Per Person
View Trip
8 Day Western Mediterranean with Cunard
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 10 August 2026
Visit: Italy, Spain, France
Exclusive Savings
Inside
-
Oceanview
$1,882
Balcony
$2,625
Suite
$4,654
From
A$1,882
Per Person
View Trip
8 Day Western Mediterranean: Italy, France & Gibraltar with Holland America
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Holland America
Ship: Nieuw Statendam
Departure: 19 February 2028
Visit: Italy, France, Gibraltar, Spain
Fare Saver
Exclusive Savings
Inside
$1,250
Oceanview
$1,507
Balcony
$1,745
Suite
$2,428
From
A$1,250
Per Person
View Trip
8 Day Western Mediterranean: Italy, France & Gibraltar with Holland America
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departures: Jul 2026 to Jun 2027
Visit: Italy, France, Gibraltar, Spain
Fare Saver
Exclusive Savings
Inside
$1,665
Oceanview
$1,814
Balcony
$2,556
Suite
$4,279
From
A$1,665
Per Person
View Trip
8 Day A Journey Of Mediterranean Colour, Cuisine & Remarkable Landmarks with Explora Journeys
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 09 October 2028
Visit: Italy, Corsica, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$6,595
From
A$6,595
Save 135
Per Person
View Trip
8 Day Regards From The Riviera with Oceania Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 09 September 2027
Visit: Italy, France, Spain
Your World Inclusions
Exclusive Savings
Inside
$2,896
Oceanview
$3,100
Balcony
$4,807
Suite
$6,514
From
A$2,896
Save 2,054
Per Person
View Trip
15 Day Mediterranean with Greece, Turkey, & Adriatic with Princess
Cruise
 (7)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Sep 2026 to Oct 2026
Visit: Italy, Greece, Turkey, Montenegro, Sicily, Spain
Princess Standard
Sanctuary Collection
Exclusive Savings
Inside
$2,465
Oceanview
$2,878
Balcony
$3,858
Suite
$4,541
From
A$2,465
Per Person
View Trip
10 Day A Journey To Spain's Icons & North Africa's Sunlit Shores with Explora Journeys
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 02 February 2027
Visit: Italy, Sicily, Tunisia, Algeria, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$7,531
From
A$7,531
Save 154
Per Person
View Trip
22 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

22 Days (21 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departure: 14 July 2028
Visit: Italy, Spain, France, Corsica (+5 more), Malta, Montenegro, Croatia, Greece, Sicily
Exclusive Savings
Inside
$6,243
Oceanview
$6,936
Balcony
$7,926
Suite
$14,658
From
A$6,243
Per Person
View Trip
10 Day A Journey From Italian Gems To Spain’s Southern Coast with Explora Journeys
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 05 March 2027
Visit: Italy, France, Corsica, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$8,085
From
A$8,085
Save 165
Per Person
View Trip
8 Day Italy, France & Spain Cruise: Rome, Nice & Barcelona with Azamara Cruises
Cruise
 (4)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 04 March 2028
Visit: Italy, France, Spain
Azamara Always Included
Exclusive Savings
Inside
$2,191
Oceanview
$2,750
Balcony
$3,573
Suite
$5,386
From
A$2,191
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 30 October 2026
Visit: Italy, Spain
Exclusive Savings
Inside
$560
Oceanview
$689
Balcony
$738
Suite
$1,144
From
A$560
Per Person
View Trip
10 Day Italian Riviera & France with Celebrity Cruises
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Jun 2026 to Aug 2026
Visit: Italy, France, Spain
Exclusive Savings
Inside
$1,583
Oceanview
$1,778
Balcony
$2,072
Suite
$7,301
From
A$1,583
Save 1,357
Per Person
View Trip
15 Day Mediterranean And Adriatic with Cunard
Cruise
 (13)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Elizabeth
Departures: Jun 2028 to Aug 2028
Visit: Italy, Malta, Montenegro, Croatia, Greece, Sicily, Spain
Exclusive Savings
Inside
$4,261
Oceanview
$4,954
Balcony
$5,597
Suite
$10,894
From
A$4,261
Per Person
View Trip
15 Day Italy, France And Spain with Cunard
Cruise
 (1)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 13 July 2026
Visit: Italy, France, Corsica, Spain
Exclusive Savings
Inside
$3,429
Oceanview
$3,786
Balcony
$4,459
Suite
$8,775
From
A$3,429
Per Person
View Trip
Results: 31-60 of 117

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