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Cruises from Rome to Barcelona

Are you looking for a cruise from Rome to Barcelona? September is the most popular month to cruise between Rome and Barcelona and there are 250 departures available from fifteen of the world's leading cruise lines.
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32 Days
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116 Cruises (250 Cruise Departures)
Cruise
 (4)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Departure: 04 March 2028
Visit: Italy, France, Spain
Azamara Always Included
Exclusive Savings
Inside
$2,191
Oceanview
$2,750
Balcony
$3,573
Suite
$5,386
From
A$2,191
Per Person
View Trip
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Departure: 26 September 2027
Visit: Italy, Monaco, France, Spain
Your World Inclusions
Exclusive Savings
Inside
$2,798
Oceanview
$3,080
Balcony
$5,020
Suite
$6,475
From
A$2,798
Save 2,052
Per Person
View Trip
Cruise
 (4)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Departure: 04 December 2027
Visit: Italy, France, Spain
Azamara Always Included
Exclusive Savings
Inside
$2,300
Oceanview
$2,868
Balcony
$3,682
Suite
$5,505
From
A$2,300
Per Person
View Trip
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Departure: 10 April 2028
Visit: Italy, Corsica, Monaco, France, Spain
Your World Inclusions
Exclusive Savings
Inside
$3,340
Oceanview
$4,320
Balcony
$5,300
Suite
$7,259
From
A$3,340
Save 2,070
Per Person
View Trip
Cruise
 (8)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Azamara Cruises
Departure: 27 May 2027
Visit: Italy, France, Spain
Azamara Always Included
Exclusive Savings
Inside
$2,869
Oceanview
$3,281
Balcony
$4,319
Suite
$6,897
From
A$2,869
Per Person
View Trip
Cruise
 (7)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Sep 2026 to Oct 2026
Visit: Italy, Greece, Turkey, Montenegro, Sicily, Spain
Princess Standard
Sanctuary Collection
Exclusive Savings
Inside
$2,465
Oceanview
$2,878
Balcony
$3,858
Suite
$4,541
From
A$2,465
Per Person
View Trip
Cruise
 (2)

22 Days (21 Nights) Rome to Barcelona
Cruise Line: Princess
Departure: 16 May 2028
Visit: Italy, Croatia, Montenegro, Greece, Turkey, Malta, Spain
Princess Standard
Exclusive Savings
Inside
$3,823
Oceanview
$4,796
Balcony
$4,514
Suite
$6,134
From
A$3,823
Per Person
View Trip
Cruise
 (3)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Departure: 15 November 2026
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Your World Inclusions
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$4,252
Suite
$5,777
From
A$4,252
Save 4,988
Per Person
View Trip
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Departure: 06 July 2027
Visit: Italy, France, Spain
Exclusive Savings
Inside
$2,174
Oceanview
$2,903
Balcony
$3,208
Suite
$7,872
From
A$2,174
Save 1,506
Per Person
View Trip
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Departure: 15 June 2026
Visit: Italy, France, Spain
Exclusive Savings
Inside
$1,710
Oceanview
-
Balcony
$4,364
Suite
-
From
A$2,449
Save 192
Per Person
View Trip
Cruise
 (7)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departures: Aug 2026 to Oct 2027
Visit: Italy, Greece, Turkey, Montenegro, Sicily, Spain
Princess Standard
Sanctuary Collection
Exclusive Savings
Inside
$2,838
Oceanview
$3,571
Balcony
$4,185
Suite
$4,917
From
A$2,838
Per Person
View Trip
Cruise
 (13)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Departure: 15 October 2027
Visit: Italy, Sicily, Greece, Croatia, Spain
First Come, First Served Offer
Exclusive Savings
Inside
$3,647
Oceanview
$3,984
Balcony
$4,499
Suite
$8,894
From
A$3,647
Per Person
View Trip
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Nova
Departure: 23 November 2026
Visit: Italy, Sicily, Tunisia, Sardinia, Spain
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$6,115
Suite
$11,662
From
A$6,115
Save 4,285
Per Person
View Trip
Cruise
 (1)

5 Days (4 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 05 December 2026
Visit: Italy, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$3,361
From
A$3,361
Save 69
Per Person
View Trip
Cruise
 (1)

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jul 2028 to Sep 2028
Visit: Italy, France, Corsica, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$7,120
From
A$7,120
Save 156
Per Person
View Trip
Cruise
 (1)

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 15 May 2028
Visit: Italy, Corsica, Monaco, France, Spain
Sky & Sea
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$6,909
From
A$6,909
Save 141
Per Person
View Trip
Cruise
 (2)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Holland America
Departure: 19 February 2028
Visit: Italy, France, Gibraltar, Spain
Fare Saver
Exclusive Savings
Inside
$1,250
Oceanview
$1,507
Balcony
$1,745
Suite
$2,428
From
A$1,250
Per Person
View Trip
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Nova
Departure: 07 November 2027
Visit: Italy, France, Spain
All-Inclusive Plus Fare
All-Inclusive Fare
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$5,468
Suite
$11,858
From
A$5,468
Save 3,832
Per Person
View Trip
Cruise
 (1)

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 30 October 2026
Visit: Italy, Spain
Exclusive Savings
Inside
$560
Oceanview
$689
Balcony
$738
Suite
$1,144
From
A$560
Per Person
View Trip
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departures: Jul 2026 to Jun 2027
Visit: Italy, France, Gibraltar, Spain
Fare Saver
Exclusive Savings
Inside
$1,665
Oceanview
$1,814
Balcony
$2,556
Suite
$4,279
From
A$1,665
Per Person
View Trip
Cruise
 (7)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departure: 04 June 2028
Visit: Italy, Sicily, Greece, Turkey, Montenegro, Spain
Princess Standard
Sanctuary Collection
Exclusive Savings
Inside
$2,706
Oceanview
$3,270
Balcony
$4,493
Suite
$4,983
From
A$2,706
Per Person
View Trip
Cruise
 (13)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Departure: 01 September 2028
Visit: Italy, Malta, Croatia, Greece, Sicily, Spain
Exclusive Savings
Inside
$4,459
Oceanview
$5,152
Balcony
$5,993
Suite
$11,191
From
A$4,459
Per Person
View Trip
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Holland America
Ship: Oosterdam
Departures: Aug 2026 to Jul 2027
Visit: Italy, Corsica, France, Gibraltar, Spain
Fare Saver
Exclusive Savings
Inside
$2,012
Oceanview
$1,868
Balcony
$2,358
Suite
$3,051
From
A$1,868
Per Person
View Trip
Cruise
 (1)

21 Days (20 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 04 January 2027
Visit: Italy, Sicily, Malta, Tunisia, Sardinia, Spain, Morocco
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$15,876
From
A$15,876
Save 324
Per Person
View Trip
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Departure: 22 September 2026
Visit: Italy, France, Spain
Exclusive Savings
Inside
$1,785
Oceanview
$2,158
Balcony
$2,979
Suite
$8,893
From
A$1,785
Save 1,244
Per Person
View Trip
Cruise
 (3)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Viking Cruises
Departures: Oct 2026 to Jun 2028
Visit: Italy, Sicily, Tunisia, Sardinia, Spain
Viking Savings Event
Bonus Shipboard Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,964
Suite
$6,414
From
A$3,964
Save 1,425
Per Person
View Trip
Cruise
 (13)

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Cunard
Departure: 22 September 2028
Visit: Italy, Malta, Croatia, Greece, Sicily, Spain
Exclusive Savings
Inside
$4,261
Oceanview
$4,756
Balcony
$5,597
Suite
$10,894
From
A$4,261
Per Person
View Trip
Cruise
 (1)

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 06 June 2028
Visit: Italy, Corsica, Spain
Sky & Sea
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$6,595
From
A$6,595
Save 135
Per Person
View Trip
Cruise
 (13)

22 Days (21 Nights) Rome to Barcelona
Cruise Line: Cunard
Departure: 30 July 2027
Visit: Italy, Malta, Croatia, Greece, Sicily, Corsica, Spain
First Come, First Served Offer
Exclusive Savings
Inside
$5,768
Oceanview
$6,402
Balcony
$7,134
Suite
$16,460
From
A$5,768
Per Person
View Trip
Cruise
 (1)

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 05 March 2027
Visit: Italy, France, Corsica, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$8,085
From
A$8,085
Save 165
Per Person
View Trip
Results: 31-60 of 116

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