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Cruises from Rome to Barcelona

Are you looking for a cruise from Rome to Barcelona? September is the most popular month to cruise between Rome and Barcelona and there are 275 departures available from sixteen of the world's leading cruise lines.
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118 Cruises (275 Departures)
118 Cruises (275 Departures)
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Duration
4 Days
32 Days
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Price
$400pp
$33,050pp
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7 Day A Journey Of Sunset Shores & Mediterranean Icons with Explora Journeys
Cruise

7 Days (6 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 08 June 2027
Visits: Italy, Corsica, Spain
Exclusive Savings
Suite
$7,918
From (Per Person)
A$7,918
Save 162
Per Person
View Trip
8 Day Yacht Harbors Of The Cote D'azur with Seabourn
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departures: Jul 2028 to Sep 2028
Visits: Italy, France, Spain
Exclusive Savings
Balcony
$8,931
Suite
$13,635
From (Per Person)
A$8,931
Save 171
Per Person
View Trip
11 Day Rome to Barcelona with Silversea
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Muse
Departure: 31 July 2026
Visits: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Exclusive Savings
Oceanview
$11,766
Balcony
$12,586
Suite
-
From (Per Person)
A$11,766
Save 1,574
Per Person
View Trip
8 Day A Journey Through Fortresses, Medinas and Balearic Splendour with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora V
Departure: 02 January 2028
Visits: Italy, Sicily, Malta, Tunisia, Spain
Exclusive Savings
Suite
$6,840
From (Per Person)
A$6,840
Save 140
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 29 October 2026
Visits: Italy, Spain
Exclusive Savings
Inside
$457
Oceanview
$556
Balcony
$833
Suite
$1,002
From (Per Person)
A$457
Per Person
View Trip
8 Day A Journey Of Treasured Secrets & Chic Promenades with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 10 August 2026
Visits: Italy, Monaco, France, Spain
Exclusive Savings
Suite
$7,080
From (Per Person)
A$7,080
Save 145
Per Person
View Trip
10 Day Glories Of The Adriatic with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania
Ship: Oceania Allura
Departure: 01 April 2029
Visits: Italy, France, Spain
Your World Inclusions
Exclusive Savings
Balcony
$5,293
Suite
$8,746
From (Per Person)
A$5,293
Save 2,147
Per Person
View Trip
8 Day Riviera Reverie with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Prestige
Departure: 30 September 2027
Visits: Italy, France, Spain
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$15,576
Suite
$16,635
From (Per Person)
A$15,576
Save 2,294
Per Person
View Trip
16 Day Mediterranean Pilgrimage with Regent Seven Seas
Cruise

16 Days (15 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 20 November 2027
Visits: Italy, Sicily, Malta, Tunisia, Sardinia, Spain, France
Exclusive Savings
Balcony
$19,647
Suite
$22,156
From (Per Person)
A$19,647
Save 2,353
Per Person
View Trip
11 Day Old World Exploration with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 01 November 2026
Visits: Italy, Malta, Tunisia, Sicily, France, Spain
Exclusive Savings
Oceanview
-
Balcony
-
Suite
$6,703
From (Per Person)
A$6,703
Save 10,267
Per Person
View Trip
8 Day Italy, Spain & French Riviera with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 16 August 2027
Visits: Italy, France, Spain
Exclusive Savings
Inside
$1,334
Oceanview
$1,913
Balcony
$2,077
Suite
$2,966
From (Per Person)
A$1,559
Save 547
Per Person
View Trip
11 Day Iconic Italy & the French Riviera with Scenic
New ReleaseCruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Scenic
Ship: Scenic Ikon
Departure: 27 June 2028
Visits: Italy, Monaco, France, Spain
Exclusive Savings
Balcony
$18,702
Suite
$22,230
From (Per Person)
A$18,702
Save 4,843
Per Person
View Trip
9 Day Monaco, Italy, France & Spain with Seabourn
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 29 June 2027
Visits: Italy, Monaco, France, Spain
Exclusive Savings
Balcony
$11,181
Suite
$15,787
From (Per Person)
A$11,181
Save 217
Per Person
View Trip
8 Day A Journey Of Antique Treasures To Sumptuous Catalan with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 07 September 2026
Visits: Italy, Monaco, France, Spain
Exclusive Savings
Suite
$7,791
From (Per Person)
A$7,791
Save 159
Per Person
View Trip
10 Day Fairytales Afloat with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania
Ship: Oceania Allura
Departure: 03 September 2027
Visits: Italy, Sicily, Sardinia, Corsica, Monaco, France, Spain
Your World Inclusions
Exclusive Savings
Balcony
$6,596
Suite
$8,420
From (Per Person)
A$6,596
Save 2,164
Per Person
View Trip
11 Day Italian & Iberian Escapade with Oceania Cruises
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania
Ship: Oceania Allura
Departure: 07 February 2029
Visits: Italy, France, Spain
Your World Inclusions
Exclusive Savings
Balcony
$4,761
Suite
$8,408
From (Per Person)
A$4,761
Save 2,129
Per Person
View Trip
11 Day Artists & Aristocrats with Oceania Cruises
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania
Ship: Oceania Allura
Departure: 07 November 2026
Visits: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Your World Inclusions
Exclusive Savings
Balcony
$4,880
Suite
-
From (Per Person)
A$4,880
Save 6,190
Per Person
View Trip
10 Day Fountains To Flamenco with Oceania Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Oceania
Ship: Oceania Sonata
Departure: 09 November 2027
Visits: Italy, Sardinia, Corsica, France, Spain
Your World Inclusions
Exclusive Savings
Balcony
$6,956
Suite
$9,400
From (Per Person)
A$6,956
Save 2,174
Per Person
View Trip
8 Day A Journey Through Italy's Rich Heritage to Catalan Elegance with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora V
Departure: 19 December 2027
Visits: Italy, Sicily, Malta, Tunisia, Sardinia, Spain
Exclusive Savings
Suite
$7,262
From (Per Person)
A$7,262
Save 148
Per Person
View Trip
15 Day Maritime Memories In The Med with Oceania Cruises
Cruise

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Oceania
Ship: Oceania Allura
Departure: 03 January 2028
Visits: Italy, Sicily, Malta, Tunisia, Sardinia, Spain, Morocco
Your World Inclusions
Exclusive Savings
Balcony
$6,827
Suite
$11,939
From (Per Person)
A$6,827
Save 2,153
Per Person
View Trip
21 Day Ode On A Grecian Journey with Oceania Cruises
Cruise

21 Days (20 Nights) Rome to Barcelona
Cruise Line: Oceania
Ship: Oceania Allura
Departure: 17 July 2027
Visits: Italy, Sicily, Malta, Greece, Montenegro, Croatia, Spain
Your World Inclusions
Exclusive Savings
Balcony
$11,947
Suite
$19,561
From (Per Person)
A$11,947
Save 2,283
Per Person
View Trip
8 Day A Journey Through Riviera Reverie & Centres Of Culture with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora VI
Departure: 02 October 2028
Visits: Italy, Corsica, France, Spain
Exclusive Savings
Suite
$6,982
From (Per Person)
A$6,982
Save 143
Per Person
View Trip
11 Day Elegant Arrivals with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Explorer
Departure: 11 July 2028
Visits: Italy, Monaco, France, Spain
Exclusive Savings
Balcony
$18,387
Suite
$20,984
From (Per Person)
A$18,387
Save 2,343
Per Person
View Trip
8 Day Monaco, Italy, France & Spain with Seabourn
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Seabourn Ovation
Departure: 18 September 2027
Visits: Italy, Monaco, France, Spain
Exclusive Savings
Balcony
$10,984
Suite
$16,962
From (Per Person)
A$10,984
Save 214
Per Person
View Trip
11 Day Western Mediterranean Cruise From Rome To Barcelona with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Dawn
Departure: 29 April 2027
Visits: Italy, Sicily, Malta, Tunisia, France, Spain
Just Cruise Fare
Exclusive Savings
Inside
$2,669
Oceanview
$3,056
Balcony
$4,351
Suite
$4,753
From (Per Person)
A$2,669
Per Person
View Trip
13 Day Masterpiece At Sea with Regent Seven Seas
Cruise

13 Days (12 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 06 October 2028
Visits: Italy, Sicily, Sardinia, Corsica, France, Spain
Exclusive Savings
Balcony
$16,987
Suite
$19,858
From (Per Person)
A$16,987
Save 2,313
Per Person
View Trip
15 Day Mediterranean Masterpieces with Oceania Cruises
Cruise

15 Days (14 Nights) Rome to Barcelona
Cruise Line: Oceania
Ship: Oceania Vista
Departure: 23 April 2028
Visits: Italy, Sicily, Malta, Tunisia, Sardinia, France, Spain
Your World Inclusions
Exclusive Savings
Balcony
$8,140
Suite
$13,688
From (Per Person)
A$8,140
Save 2,230
Per Person
View Trip
11 Day Civitavecchia (Rome) to Barcelona with Silversea
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 29 May 2027
Visits: Italy, France, Corsica, Monaco, Spain
Exclusive Savings
Balcony
$15,827
Suite
$21,413
From (Per Person)
A$15,827
Save 323
Per Person
View Trip
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